Material Safety Data Sheet
According to NOHSC:2007(1994)
Australia
English
1 . Chemical Product and Company Identification
Benzamidine Sepharose鈩? 4 Fast Flow (high sub), 25
Product name :
ml
9017512310
Catalogue Number :
17-5123-10
9517512310
Article Number :
STATEMENT OF HAZARDOUS NATURE
! Not classified as hazardous according to the criteria of NOHSC nor classified as dangerous goods according to the ADG Code.
Manufacturer Supplier
Amersham Biosciences Amersham Biosciences Pty Ltd
SE-751 84 Uppsala Unit 1, 22 Hudson Avenue
Sweden Castle Hill, NSW 2154
+46 (0) 18 612 0000 Australia
+61 2 9899 0999
Emergency telephone number 000 or +61 2 9899 0999
Area of Application : Industrial applications.
Product Use : Industrial applications: Analytical chemistry. Research. Liquid chromatography.
Composition/information on ingredients
2.
: Yes.
Mixture
Chemical name CAS no. % by Weight
Ethanol 64-17-5 18-24
Suspension (Chromatography/Separation Media)
water 7732-18-5
3. Hazards identification
Emergency Overview
: Liquid. (and Suspension)
Appearance
: Sweetish. Slight Alcohol-like.
Odour
: Flammable.
Physical/chemical Hazards
Dangerous Goods Classification (ADG Code)
Not regulated as Dangerous Goods according to the ADG Code
Source: SUSDP
: Not available.
Poison Schedule (Australia)
Source: NZ Toxic
: Not available.
Toxic Substances Schedule (NZ)
Substances Regulations
Potential Acute Health Effects
: Slightly hazardous in case of inhalation.
Inhalation
: Slightly hazardous in case of ingestion.
Ingestion
: Irritation of the product in case of skin contact: Not available. Sensitization of the
Skin contact
product: Not available.
: Not available.
Eye Contact
: Repeated or prolonged exposure is not known to aggravate medical condition.
Potential Chronic Health Effects
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Benzamidine Sepharose鈩? 4 Fast Flow (high sub), 25 ml 17-5123-10
4. First-aid measures
First-aid measures
Inhalation : If inhaled, remove to fresh air.
If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention if symptoms appear.
Ingestion : No specific treatment, treat symptomatically. Call medical doctor or poison
control centre immediately if large quantities are ingested.
Do NOT induce vomiting unless directed to do so by medical personnel. Never give
anything by mouth to an unconscious person. Loosen tight clothing such as a collar,
tie, belt or waistband. Get medical attention if symptoms appear.
Skin contact : Wash with soap and water.
Get medical attention if irritation develops. Cold water may be used.
Eye Contact : Check for and remove any contact lenses. In case of contact, immediately flush
eyes with a copious amount of water for at least 15 minutes.
Cold water may be used. Get medical attention if irritation occurs.
5. Fire-fighting measures
: Flammable liquid. Suspension
Nature of Material / Extinguishing
SMALL FIRE: Use DRY chemical powder.
media
LARGE FIRE: Use alcohol foam, water spray or fog. Cool containing vessels with
water jet in order to prevent pressure build-up, autoignition or explosion.
: These products are carbon oxides (CO, CO2).
Hazardous thermal (de)composition
products
: Fire fighters should wear self-contained positive pressure breathing apparatus
Special fire-fighting procedures
(SCBA) and full turnout gear.
: Be sure to use an approved/certified respirator or equivalent.
Protection of fire-fighters
6. Accidental release measures
: Splash goggles. Full suit. Boots. Gloves. Suggested protective clothing might not
Personal Precautions
be sufficient; consult a specialist BEFORE handling this product.
Environmental precautions and cleanup : Keep away from heat. Keep away from sources of ignition. Stop leak if without risk.
Absorb with dry earth, sand or other noncombustible material. Do not touch spilled
methods
material. Prevent entry into sewers, basements or confined areas; dike if needed.
Finish cleaning by spreading water on the contaminated surface and allow to evacuate
through the sanitary system.
7. Handling and storage
: Keep away from heat. Keep away from sources of ignition.
Handling
Do not breathe gas/fumes/vapour/spray. If you feel unwell, seek medical attention
and show the label when possible. Wear suitable protective clothing.
Keep away from incompatibles such as oxidizing agents.
: Keep container in a cool, well-ventilated area. Keep container tightly closed and
Storage
sealed until ready for use. Avoid all possible sources of ignition (spark or flame).
Packaging materials
: Use original container.
Recommended use
8 . Exposure controls/personal protection
Occupational Exposure Limits
Ingredient Name Occupational Exposure Limits
Ethanol NOHSC (Australia, 2002). Notes: Documentation for the substances with this
footnote can be found in the 5th Edition of the ACGIH documentation of the
threshold limit values and biological exposure indices.1 For all other substances
with 'H' in Column 7 the documentation can be found i n the 6th Edition of the
ACGIH documentation of the threshold limit values and biological exposure
indices.2
TWA: 1880 mg/m3 8 hour(s).
TWA: 1000 ppm 8 hour(s).
: Provide exhaust ventilation or other engineering controls to keep the airborne
Engineering measures
concentrations of vapours below their respective occupational exposure limits.
Ensure that eyewash stations and safety showers are close to the workstation location.
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Benzamidine Sepharose鈩? 4 Fast Flow (high sub), 25 ml 17-5123-10
: Wash hands after handling compounds and before eating, smoking, using lavatory,
Hygiene measures
and at the end of day.
Personal protective equipment
: Wear appropriate respirator when ventilation is inadequate.
Respiratory system
: Lab coat.
Skin and body
: Impervious gloves.
Hands
: Safety glasses.
Eyes
: Respiratory protection should conform to AS/NZS 1715 and AS/NZS 1716.
Notes
Eye protectors should conform to AS/NZS 1336 and AS/NZS 1337.
Chemically resistant gloves should conform to AS/NZS 2161.1.
Protective clothing should conform to AS 3765.1 or AS 3765.2.
Occupational footwear should conform to AS/NZS 2210.
9. Physical and chemical properties
: Liquid. (and Suspension)
Physical state
Colour : solution : Colourless. / Suspension : White.
Odour : Sweetish. Slight Alcohol-like.
Odour threshold : 180 ppm: Calculated value for the mixture
: The lowest known value is 78.4掳C (173.1掳F) (Ethanol).
Boiling point
: May start to solidify at 0掳C (32掳F) based on data for: water.
Melting point
: The highest known value is 5.3 kPa (40 mmHg) (at 20掳C) (Ethanol).
Vapour pressure
: The only known value is 0.79 (Water = 1) (Ethanol).
Specific gravity
: Closed cup: 36掳C (96.8掳F).
Flash point
: Not considered as a product presenting risks of explosion.
Explosive properties
: The greatest known range is LOWER: 3.3% UPPER: 19% (Ethanol)
Flammable Limits
: The highest known value is 1.6 (Air = 1) (Ethanol).
Vapour density
: The lowest known value is 398.9掳C (750掳F) (Ethanol).
Autoignition temperature
: The highest known value is 1.7 (Ethanol) Weighted average: 0.76compared to Butyl
Evaporation rate (butyl acetate = 1)
acetate.
: Not applicable. (Suspension)
Solubility
10 . Stability and reactivity
: The product is stable.
Stability
Materials to avoid : Incompatibility : hydrogen peroxide ; perchloric acid ; nitric acid ; metal perchlorates
; metal nitrates ; sodium metals ; potassium metals ; acid anhydrides ; acid chlorides
: These products are carbon oxides (CO, CO2).
Hazardous decomposition products
: Incompatibilities : Strong oxidizers, potassium dioxide, bromine pentafluoride, acetyl
Remarks
bromide, acetyl chloride, platinum, sodium--NIOSHP; Acetaldehyde, Barium
perchlorate, Chlorine, Diethyl aluminum bromide, Ethylene oxide, Hexamethylene
diisocyanate, Hydrogen peroxide and Sulfuric acid, Hypochlorous acid, Isocyanates,
Lithium aluminum hydride, Nitrogen tetroxide, Perchloric acid, Permonosulfuric acid,
Tri-iso-butyl aluminum--NFPA 491M Reactions with other materials :
Reactions with common materials : DANGEROUS: CAN REACT VIGOROUSLY
WITH OXIDIZING MATERIALS ,SAX (Ethanol)
11 . Toxicological information
Local effects
Skin irritation : Not available.
: This product may irritate eyes upon contact.
Eye irritation
Toxicity Data Test Result Route Species
Ethanol 99.9% LD50 7060 mg/kg Oral Rat
LD50 6300 mg/kg Oral Rabbit
LD50 3450 mg/kg Oral Mouse
LD50 >20000 mg/kg Dermal Rabbit
LDLo 1400 mg/kg Oral human
LDLo 5500 mg/kg Oral Dog
LC50 8000 mg/l (4 INHALATION Rat
hours)
Specific effects
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Benzamidine Sepharose鈩? 4 Fast Flow (high sub), 25 ml 17-5123-10
: Classified None. by NIOSH [Ethanol]. Classified A4 (Not classifiable for humans or
Carcinogenic effects
animals.) by ACGIH [Ethanol].
: Not available.
Mutagenic Effects
: Classified Reproductive system/toxin/female, Reproductive system/toxin/male
Reproduction toxicity
[PROVEN] [Ethanol].
12 . Ecological information
Persistence/degradability : Theoretical Oxygen Demand:
ThOD: 75000 to 84000 mg/l [20 day(s)] [Ethanol]
: Not available.
Ecotoxicity
13 . Disposal considerations
: All waste must be disposed of in accordance with Local Authority, State Pollution
Methods of disposal ; Waste of
Control Commission, EPA or Metropolitan Waste Disposal Authority requirements.
residues ; Contaminated packaging
14 . Transport information
Regulation UN Proper shipping name Class Sub-Risk PG Additional Information
number
Not - - - -
ADG
regulated.
Not - - - - -
IMDG
regulated.
Not - - - - -
IATA
regulated.
15 . Regulatory information
: S23 - Do not breathe vapour.
Safety Phrases
: Not available.
Carcinogenic Substances Schedule
(NOHSC)
: Australia (NICNAS): Ethanol; water
Australian Inventory Status
16 . Other information
: Indicates information that has changed from previously issued version.
Date of previous issue : No Previous Validation
To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its
subsidiaries assumes any liability whatsoever for the accuracy or completeness of the information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and
should be used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that
exist.
Enquiries regarding MSDS Content should be directed to: your local Amersham Biosciences office.
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