SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 31/JAN/2005
Date Updated: 13/MAR/2004
Version 1.3
According to 91/155/EEC
1 - Product and Company Information
Product Name BENZOIN
Product Number 12510
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
BENZOIN 119-53-9 204-331-3 None
Formula C14H12O2
Molecular Weight 212.25 AMU
Synonyms Acetophenone, 2-hydroxy-2-phenyl- *
Benzoylphenylcarbinol * Bitter almond oil
camphor * Ethanone, 2-hydroxy-1,2-diphenyl- *
Fenyl-alpha-hydroxybenzylketon (Czech) *
alpha-Hydroxybenzyl phenyl ketone *
alpha-Hydroxy-alpha-phenylacetophenone *
2-Hydroxy-2-phenylacetophenone * Ketone,
alpha-hydroxybenzyl phenyl * NCI-C50011 *
WY-42956
3 - Hazards Identification
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact, immediately flush eyes with copious amounts
of water for at least 15 minutes.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear respirator, chemical safety goggles, rubber boots, and
heavy rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Avoid inhalation. Avoid contact
with eyes, skin, and clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed. Store in a cool dry
place.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaust required.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling. Wash contaminated clothing before
reuse.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Color: Slightly yellow
Form: Fine crystals
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 194 掳C 12 mmHg
MP/MP Range 133 掳C
Flash Point 181 掳C Method: closed cup
Flammability N/A
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Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density N/A
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
11 - Toxicological Information
RTECS NUMBER: DI1590000
ACUTE TOXICITY
LD50
Oral
Rat
10000 mg/kg
LD50
Oral
Mouse
> 3000 mg/kg
Remarks: Behavioral:Somnolence (general depressed activity).
LD50
Skin
Rabbit
8870 mg/kg
SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Eye Contact: May cause eye irritation.
Inhalation: Material may be irritating to mucous membranes and
upper respiratory tract.
Multiple Routes: May be harmful by inhalation, ingestion, or
skin absorption.
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CHRONIC EXPOSURE - MUTAGEN
Rat
63700 UG/L
Cell Type: liver
DNA damage
Rat
500 MG/KG
Intraperitoneal
DNA damage
Rat
1 MMOL/L
Cell Type: liver
Unscheduled DNA synthesis
Rat
1 GM/KG
Oral
Unscheduled DNA synthesis
Mouse
10 MG/L (+S9)
Cell Type: lymphocyte
Mutation in microorganisms
Mouse
500 MG/KG
Intraperitoneal
Unscheduled DNA synthesis
Mouse
62500 UG/L
Cell Type: lymphocyte
Mutation in mammalian somatic cells.
Hamster
20 MG/L
Cell Type: lung
Cytogenetic analysis
Hamster
500 MG/L
Cell Type: ovary
Sister chromatid exchange
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Dissolve or mix the material with a combustible solvent and burn
in a chemical incinerator equipped with an afterburner and
scrubber. Observe all federal, state, and local environmental
regulations.
14 - Transport Information
RID/ADR
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Non-hazardous for road transport.
IMDG
Non-hazardous for sea transport.
IATA
Non-hazardous for air transport.
15 - Regulatory Information
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 2
SWITZERLAND
SWISS POISON CLASS: 3
16 - Other Information
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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