SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 02/FEB/2005
Date Updated: 10/JUN/2004
Version 1.5
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name BENZYL ALCOHOL, ANHYDROUS, 99.8%
Product Number 305197
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
BENZYL ALCOHOL 100-51-6 202-859-9 603-057-00-5
Formula C7H8O
Molecular Weight 108.14 AMU
Synonyms Benzal alcohol * Benzenecarbinol *
Benzenemethanol * Benzoyl alcohol *
Hydroxytoluene * alpha-Hydroxytoluene *
Methanol, phenyl- * NCI-C06111 * Phenolcarbinol
* Phenylcarbinol * Phenylmethanol * Phenylmethyl
alcohol * alpha-Toluenol
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Harmful by inhalation and if swallowed.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If breathing becomes difficult,
call a physician.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Absorb on sand or vermiculite and place in closed containers for
disposal. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Avoid
contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.
STORAGE
Conditions of Storage: Keep tightly closed. Handle and store
under nitrogen. Store in a cool dry place.
SPECIAL REQUIREMENTS: Handle and store under inert gas.
Hygroscopic.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaust required.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
EXPOSURE LIMITS
Country Source Type Value
Poland NDS 240 mg/m3
Poland NDSCh -
Poland NDSP
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
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9 - Physical and Chemical Properties
Appearance Physical State: Clear liquid
Color: Colorless
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 90 - 93 掳C 10 mmHg
MP/MP Range -16 掳C
Flash Point 96 掳C Method: closed cup
Flammability N/A
Autoignition Temp 436 掳C
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure 3.75 mmHg 77 掳C
SG/Density 1.044 g/cm3
Partition Coefficient Log Kow: 1.1
Viscosity 0.005 Pas 25 掳C
Vapor Density 3.7 g/l
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension 39 mN/m 20 掳C
Conductivity N/A
Miscellaneous Data N/A
Solubility Solubility in Water:33 mg/ml H2O, 20掳C
clear, colorless
Other Solvents: SOLUBLE IN ETHANOL, ETHER
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Conditions of Instability: Hygroscopic.
Conditions to Avoid: A mixture of benzyl alcohol and 58% sulfuric
acid decomposed violently when heated to 180掳C. Benzyl alcohol
containing 1.4% hydrogen bromide and 1.1% of an iron(II) salt
polymerized exothermally when heated above 100掳C.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: DN3150000
ACUTE TOXICITY
LD50
Oral
Rat
1230 mg/kg
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Remarks: Behavioral:Somnolence (general depressed activity).
Behavioral:Excitement. Behavioral:Coma.
LD50
Intraperitoneal
Rat
400 MG/KG
LD50
Intravenous
Rat
53 MG/KG
Remarks: Lungs, Thorax, or Respiration:Dyspnea.
LD50
Intraarterial
Rat
441 MG/KG
Remarks: Lungs, Thorax, or Respiration:Chronic pulmonary edema.
Lungs, Thorax, or Respiration:Dyspnea.
LD50
Oral
Mouse
1360 mg/kg
LD50
Intraperitoneal
Mouse
650 MG/KG
Remarks: Behavioral:Altered sleep time (including change in
righting reflex). Behavioral:Somnolence (general depressed
activity). Lungs, Thorax, or Respiration:Dyspnea.
LD50
Intravenous
Mouse
324 MG/KG
LD50
Oral
Rabbit
1040 mg/kg
Remarks: Behavioral:Somnolence (general depressed activity).
LD50
Skin
Rabbit
2000 mg/kg
LD50
Oral
Guinea pig
2500 mg/kg
LD50
Oral
Bird (wild)
100 mg/kg
IRRITATION DATA
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Skin
Man
16 mg
48H
Remarks: Mild irritation effect
Skin
Rabbit
100 mg
24H
Remarks: Moderate irritation effect
Skin
Pig
100 %
Remarks: Moderate irritation effect
SIGNS AND SYMPTOMS OF EXPOSURE
Can cause CNS depression.
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: Harmful if inhaled. Material may be irritating to
mucous membranes and upper respiratory tract.
Ingestion: Harmful if swallowed.
TARGET ORGAN INFORMATION
Central nervous system.
CHRONIC EXPOSURE - MUTAGEN
Rat
10 MMOL/L
Cell Type: liver
DNA damage
Mouse
250 MG/L (+S9)
Cell Type: lymphocyte
Mutation in microorganisms
Hamster
4 UG/L
Cell Type: ovary
Cytogenetic analysis
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Mouse
Dose: 6 GM/KG
Route of Application: Oral
Exposure Time: (6-13D PREG)
Result: Effects on Newborn: Growth statistics (e.g., reduced
weight gain).
12 - Ecological Information
ECOTOXICOLOGICAL EFFECTS
Test Type: EC50 Daphnia
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Species: Daphnia magna
Time: 24 h
Value: 55 mg/l
Test Type: LC50 Fish
Species: Lepomis macrochirus (Bluegill)
Time: 96 h
Value: 10 mg/l
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
Non-hazardous for road transport.
IMDG
Non-hazardous for sea transport.
IATA
Non-hazardous for air transport.
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 603-057-00-5
INDICATION OF DANGER: Xn
Harmful.
R-PHRASES: 20/22
Harmful by inhalation and if swallowed.
S-PHRASES: 26
In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 1
SWITZERLAND
SWISS POISON CLASS: 4
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
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paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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