SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 30/JAN/2005
Date Updated: 21/DEC/2004
Version 1.9
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name BENZENE, ANHYDROUS, 99.8%
Product Number 401765
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
BENZENE 71-43-2 200-753-7 601-020-00-8
Formula C6H6
Molecular Weight 78.11 AMU
Synonyms (6)Annulene * Benzeen (Dutch) * Benzen (Polish)
* Benzene (ACGIH:OSHA) * Benzin (Obs.) * Benzine
(Obs.) * Benzol (OSHA) * Benzole * Benzolene *
Benzolo (Italian) * Bicarburet of hydrogen *
Carbon oil * Coal naphtha * Cyclohexatriene *
Fenzen (Czech) * Mineral naphtha * NCI-C55276 *
Phene * Phenyl hydride * Pyrobenzol *
Pyrobenzole * RCRA waste number U019
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
May cause cancer. Highly flammable. Toxic: danger of serious
damage to health by prolonged exposure through inhalation, in
contact with skin and if swallowed.
Carc. Cat.1
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Flammable liquid. Vapor may travel
considerable distance to source of ignition and flash back.
Emits toxic fumes under fire conditions.
Explosion Hazards: Vapor may travel considerable distance to
source of ignition and flash back. Container explosion may occur
under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area. Shut off all sources of ignition.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Cover with dry-lime, sand, or soda ash. Place in covered
containers using non-sparking tools and transport outdoors.
Ventilate area and wash spill site after material pickup is
complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Avoid
contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.
STORAGE
Conditions of Storage: Keep container closed. Keep away from
heat, sparks, and open flame.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Use nonsparking tools. Use only in a
chemical fume hood.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Wash thoroughly after
handling.
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EXPOSURE LIMITS
Country Source Type Value
Poland NDS 1.6
Poland NDSCh -
Poland NDSP -
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 1.6 mg/m3
0.5 ppm
Remarks: HK
EXPOSURE LIMITS - GERMANY
Source Type Value
TRGS 900 OEL 1 ppm
3.25 mg/m3
Remarks: 4
Remarks: H,TRK, TRGS 901-15
EXPOSURE LIMITS - NORWAY
Source Type Value
OEL 3 mg/m3
1 ppm
Remarks: K
EXPOSURE LIMITS - SWEDEN
Source Type Value
LLV (Level1.5 mg/m3
0.5 ppm
Remarks: H, K
EXPOSURE LIMITS - SWITZERLAND
Source Type Value
OEL OEL 3.2 mg/m3
1 ppm
Remarks: H K
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL OEL 3 ppm
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Liquid
Color: Colorless
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 80 - 80.2 掳C 760 mmHg
MP/MP Range 5.5 掳C
Flash Point -11 掳C Method: closed cup
Flammability N/A
Autoignition Temp 562 掳C
Oxidizing Properties N/A
Explosive Properties N/A
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Explosion Limits Lower: 1.3 %
Upper: 8 %
Vapor Pressure 74.6 mmHg 20 掳C
SG/Density 0.879 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density 2.77 g/l
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Acids, Bases, Halogens, Strong oxidizing
agents, Avoid contact with metal salts.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: CY1400000
ACUTE TOXICITY
LCLO
Inhalation
Human
2 PPH/5M
LDLO
Oral
Man
50 mg/kg
LCLO
Inhalation
Human
65 mg/m3
5Y
Remarks: Blood:Other changes.
LD50
Oral
Rat
930 mg/kg
Remarks: Behavioral:Tremor. Behavioral:Convulsions or effect on
seizure threshold.
LC50
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Inhalation
Rat
10,000 ppm
7H
LD50
Intraperitoneal
Rat
1100 UG/KG
LD50
Oral
Mouse
4700 mg/kg
LC50
Inhalation
Mouse
9,980 ppm
Remarks: Behavioral:General anesthetic. Behavioral:Muscle
weakness. Lungs, Thorax, or Respiration:Dyspnea.
LD50
Skin
Mouse
48 mg/kg
LD50
Intraperitoneal
Mouse
340 MG/KG
LD50
Skin
Rabbit
>9400 UL/KG
LD50
Skin
Guinea pig
>9400 UL/KG
LD50
Oral
Mammal
5700 mg/kg
IRRITATION DATA
Skin
Rabbit
15 mg
24H
Remarks: Open irritation test
Skin
Rabbit
20 mg
24H
Remarks: Moderate irritation effect
Eyes
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Rabbit
88 mg
Remarks: Moderate irritation effect
Eyes
Rabbit
2 mg
24H
Remarks: Severe irritation effect
SIGNS AND SYMPTOMS OF EXPOSURE
Exposure can cause: Nausea, dizziness, and headache. Narcotic
effect. Inhalation of high concentrations of benzene may have an
initial stimulatory effect on the central nervous system
characterized by exhilaration, nervous excitation and/or
giddiness, depression, drowsiness, or fatigue. The victim may
experience tightness in the chest, breathlessness, and loss of
consciousness. Tremors, convulsions, and death due to
respiratory paralysis or circulatory collapse can occur in a few
minutes to several hours following severe exposures. Aspiration
of small amounts of liquid immediately causes pulmonary edema
and hemorrhage of pulmonary tissue. Direct skin contact may
cause erythema. Repeated or prolonged skin contact may result in
drying, scaling dermatitis, or development of secondary skin
infections. The chief target organ is the hematopoietic system.
Bleeding from the nose, gums, or mucous membranes and the
development of purpuric spots, pancytopenia, leukopenia,
thrombocytopenia, aplastic anemia, and leukemia may occur as the
condition progresses. The bone marrow may appear normal,
aplastic or hyperplastic, and may not correlate with peripheral
blood-forming tissues. The onset of effects of prolonged benzene
exposure may be delayed for many months or years after the
actual exposure has ceased. Blood effects.
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: Toxic if absorbed through skin.
Eye Contact: Causes severe eye irritation.
Inhalation: Toxic if inhaled. Vapor or mist is irritating to the
mucous membranes and upper respiratory tract.
Ingestion: Toxic if swallowed.
TARGET ORGAN INFORMATION
Blood. Bone marrow. Eyes. Female reproductive system.
CHRONIC EXPOSURE - CARCINOGEN
Result: This is or contains a component that has been reported
to be carcinogenic based on its IARC, OSHA, ACGIH, NTP, or EPA
classification.
Man
Route of Application: Inhalation
Exposure Time: 78W-
Result: Tumorigenic:Carcinogenic by RTECS criteria.
Blood:Leukemia Blood:Thrombocytopenia.
Human
Route of Application: Inhalation
Exposure Time: 8H/10Y
Result: Tumorigenic:Carcinogenic by RTECS criteria.
Blood:Leukemia
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Rat
Route of Application: Oral
Exposure Time: 52W
Result: Tumorigenic:Carcinogenic by RTECS criteria.
Endocrine:Tumors. Blood:Leukemia
Rat
Route of Application: Inhalation
Exposure Time: 6H/10W
Result: Tumorigenic:Equivocal tumorigenic agent by RTECS
criteria. Sense Organs and Special Senses (Nose, Eye, Ear, and
Taste):Ear:Tumors.
Mouse
Route of Application: Oral
Exposure Time: 2Y
Result: Tumorigenic:Carcinogenic by RTECS criteria.
Endocrine:Tumors. Blood:Lymphomas including Hodgkin's disease.
Mouse
Route of Application: Inhalation
Exposure Time: 6H/16W
Result: Tumorigenic:Equivocal tumorigenic agent by RTECS
criteria. Blood:Lymphomas including Hodgkin's disease.
Mouse
Route of Application: Skin
Exposure Time: 49W
Result: Tumorigenic:Neoplastic by RTECS criteria. Skin and
Appendages: Other: Tumors.
Mouse
Route of Application: Intraperitoneal
Exposure Time: 8W
Result: Tumorigenic:Neoplastic by RTECS criteria. Lungs, Thorax,
or Respiration:Tumors.
Mouse
Route of Application: Subcutaneous
Exposure Time: 17W
Result: Tumorigenic:Equivocal tumorigenic agent by RTECS
criteria. Blood:Leukemia Blood:Lymphomas including Hodgkin's
disease.
Mouse
Route of Application: Parenteral
Exposure Time: 19W
Result: Tumorigenic:Equivocal tumorigenic agent by RTECS
criteria. Blood:Leukemia Blood:Lymphomas including Hodgkin's
disease.
Human
Route of Application: Inhalation
Exposure Time: 15M/8Y
Result: Tumorigenic:Carcinogenic by RTECS criteria.
Blood:Leukemia
Rat
Route of Application: Oral
Exposure Time: 1Y
Result: Tumorigenic:Carcinogenic by RTECS criteria. Sense Organs
and Special Senses (Nose, Eye, Ear, and Taste):Ear:Tumors.
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Blood:Leukemia
Rat
Route of Application: Oral
Exposure Time: 52W
Result: Tumorigenic:Carcinogenic by RTECS criteria.
Endocrine:Tumors. Blood:Leukemia
Man
Route of Application: Inhalation
Exposure Time: 4Y-
Result: Tumorigenic:Carcinogenic by RTECS criteria.
Blood:Leukemia
Man
Route of Application: Inhalation
Exposure Time: 11Y
Result: Tumorigenic:Carcinogenic by RTECS criteria.
Blood:Lymphomas including Hodgkin's disease.
Mouse
Route of Application: Inhalation
Exposure Time: 6H/10W
Result: Tumorigenic:Equivocal tumorigenic agent by RTECS
criteria. Sense Organs and Special Senses (Nose, Eye, Ear, and
Taste):Ear:Tumors. Lungs, Thorax, or Respiration:Tumors.
Mouse
Route of Application: Oral
Exposure Time: 8W
Result: Tumorigenic:Neoplastic by RTECS criteria. Lungs, Thorax,
or Respiration:Tumors.
Human
Route of Application: Inhalation
Exposure Time: 4W
Result: Tumorigenic:Carcinogenic by RTECS criteria.
Blood:Leukemia
Human
Route of Application: Inhalation
Exposure Time: 11Y-
Result: Tumorigenic:Carcinogenic by RTECS criteria.
Blood:Leukemia
Mouse
Route of Application: Inhalation
Exposure Time: 6H/16W
Result: Tumorigenic:Carcinogenic by RTECS criteria.
Blood:Leukemia
IARC CARCINOGEN LIST
Rating: Group 1
CHRONIC EXPOSURE - MUTAGEN
Result: Laboratory experiments have shown mutagenic effects.
Human
2200 UMOL/L
Cell Type: leukocyte
DNA inhibition
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Human
2200 UMOL/L
Cell Type: HeLa cell
DNA inhibition
Human
5 UMOL/L
Cell Type: lymphocyte
Other mutation test systems
Human
125 PPM
Inhalation
1Y
Cytogenetic analysis
Human
1 MMOL/L
72H
Cell Type: leukocyte
Cytogenetic analysis
Human
1 MG/L
Cell Type: lymphocyte
Cytogenetic analysis
Human
10 PPM
Unreported
4W
Cytogenetic analysis
Human
200 UMOL/L
Cell Type: lymphocyte
Sister chromatid exchange
Human
1 GM/L
Cell Type: lymphocyte
Mutation in mammalian somatic cells.
Rat
1 PPM
Inhalation
6H
Micronucleus test
Rat
1 MMOL/L
Cell Type: liver
Unscheduled DNA synthesis
Rat
400 PPM
Inhalation
DNA inhibition
Rat
1 MMOL/L
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Cell Type: liver
Other mutation test systems
Rat
1 MMOL/L
Cell Type: Bone marrow
Other mutation test systems
Rat
1 GM/L
Subcutaneous
Other mutation test systems
Rat
2200 MG/KG
Subcutaneous
Other mutation test systems
Rat
300 MG/M3/16W-I
Inhalation
Cytogenetic analysis
Rat
2400 MG/KG
Subcutaneous
12D
Cytogenetic analysis
Rat
234 MG/KG
Intraperitoneal
Cytogenetic analysis
Rat
39060 UG/KG
Oral
Cytogenetic analysis
Rat
3 PPM
Inhalation
6H
Sister chromatid exchange
Rat
1 MMOL/L
Cell Type: leukocyte
Sister chromatid exchange
Mouse
12500 NMOL/L
Cell Type: Embryo
Micronucleus test
Mouse
440 MG/KG
Subcutaneous
Micronucleus test
Mouse
40 MG/KG
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Oral
Micronucleus test
Mouse
264 MG/KG
Intraperitoneal
24H
Micronucleus test
Mouse
10 PPM
Inhalation
6H
Micronucleus test
Mouse
62500 UG/L (+S9)
Cell Type: lymphocyte
Mutation in microorganisms
Mouse
2500 MG/L (+S9)
Cell Type: Embryo
Mutation in microorganisms
Mouse
1 GM/L
Cell Type: Embryo
Morphological transformation.
Mouse
150 GM/L
Cell Type: fibroblast
Morphological transformation.
Mouse
3840 UMOL/L
Cell Type: lymphocyte
DNA damage
Mouse
2640 MG/KG
Intraperitoneal
3D
DNA
Mouse
2 GM/KG
Oral
Other mutation test systems
Mouse
5 MMOL/L
Cell Type: Other cell types
Other mutation test systems
Mouse
20 GM/KG
Oral
DNA inhibition
Mouse
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10 MMOL/L
Cell Type: lymphocyte
Other mutation test systems
Mouse
880 MG/KG
Intraperitoneal
DNA inhibition
Mouse
3000 PPM
Inhalation
4H
DNA inhibition
Mouse
3 MMOL/L
Cell Type: Bone marrow
DNA inhibition
Mouse
10 PPM
Inhalation
6H
Sister chromatid exchange
Mouse
5 GM/KG
Intraperitoneal
Sister chromatid exchange
Mouse
20 MG/KG
Oral
Cytogenetic analysis
Mouse
264 MG/KG
Intraperitoneal
3D
Cytogenetic analysis
Mouse
3000 PPM
Inhalation
Cytogenetic analysis
Mouse
1 MG/KG
Oral
Dominant lethal test
Mouse
5 MG/KG
Intraperitoneal
Dominant lethal test
Mouse
12500 UG/L
Cell Type: lymphocyte
Mutation in mammalian somatic cells.
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Mouse
40 PPB/6W-C
Inhalation
Mutation in mammalian somatic cells.
Mouse
2 GM/KG
Oral
5D
Mutation in mammalian somatic cells.
Hamster
100 UG/L
Cell Type: Embryo
Morphological transformation.
Hamster
17 MMOL/L
Cell Type: ovary
DNA damage
Hamster
550 MG/L
Cell Type: lung
Cytogenetic analysis
Hamster
600 MG/L
Cell Type: ovary
Cytogenetic analysis
Hamster
750 MG/L
Cell Type: ovary
Sister chromatid exchange
Hamster
62500 UG/L
Cell Type: liver
SLN
Hamster
30 UMOL/L
Cell Type: Embryo
SLN
Hamster
10 UMOL/L
Cell Type: Embryo
Mutation in mammalian somatic cells.
Rabbit
2344 MG/KG
Subcutaneous
DNA damage
Rabbit
2 GM/KG
Subcutaneous
DNA inhibition
Rabbit
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1 MMOL/L
Cell Type: Bone marrow
Other mutation test systems
Cat
1 MMOL/L
Cell Type: Bone marrow
Other mutation test systems
Rabbit
8400 MG/KG
Subcutaneous
Cytogenetic analysis
CHRONIC EXPOSURE - TERATOGEN
Species: Rat
Dose: 50 PPM/24H
Route of Application: Inhalation
Exposure Time: (7-14D PREG)
Result: Effects on Embryo or Fetus: Extra embryonic structures
(e.g., placenta, umbilical cord). Effects on Embryo or Fetus:
Fetotoxicity (except death, e.g., stunted fetus).
Species: Mouse
Dose: 9 GM/KG
Route of Application: Oral
Exposure Time: (6-15D PREG)
Result: Effects on Embryo or Fetus: Fetotoxicity (except death,
e.g., stunted fetus).
Species: Mouse
Dose: 500 PPM/7H
Route of Application: Inhalation
Exposure Time: (6-15D PREG)
Result: Effects on Embryo or Fetus: Fetotoxicity (except death,
e.g., stunted fetus). Specific Developmental Abnormalities:
Musculoskeletal system.
Species: Mouse
Dose: 500 MG/M3/12H
Route of Application: Inhalation
Exposure Time: (6-15D PREG)
Result: Effects on Embryo or Fetus: Fetotoxicity (except death,
e.g., stunted fetus). Specific Developmental Abnormalities:
Musculoskeletal system.
Species: Mouse
Dose: 5 PPM
Route of Application: Inhalation
Exposure Time: (6-15D PREG)
Result: Effects on Embryo or Fetus: Cytological changes
(including somatic cell genetic material). Specific
Developmental Abnormalities: Blood and lymphatic system
(including spleen and marrow).
Species: Mouse
Dose: 20 PPM/6H
Route of Application: Inhalation
Exposure Time: (6-15D PREG)
Result: Specific Developmental Abnormalities: Blood and
lymphatic system (including spleen and marrow).
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Species: Mouse
Dose: 219 MG/KG
Route of Application: Intraperitoneal
Exposure Time: (14D PREG)
Result: Specific Developmental Abnormalities: Blood and
lymphatic system (including spleen and marrow). Specific
Developmental Abnormalities: Hepatobiliary system.
Species: Mouse
Dose: 1100 MG/KG
Route of Application: Subcutaneous
Exposure Time: (12D PREG)
Result: Effects on Embryo or Fetus: Other effects to embryo.
Species: Mouse
Dose: 7030 MG/KG
Route of Application: Subcutaneous
Exposure Time: (12-13D PREG)
Result: Effects on Embryo or Fetus: Extra embryonic structures
(e.g., placenta, umbilical cord). Effects on Embryo or Fetus:
Fetotoxicity (except death, e.g., stunted fetus). Specific
Developmental Abnormalities: Musculoskeletal system.
Species: Mouse
Dose: 13200 UG/KG
Route of Application: Intravenous
Exposure Time: (13-16D PREG)
Result: Effects on Embryo or Fetus: Cytological changes
(including somatic cell genetic material).
Species: Rabbit
Dose: 1 GM/M3/24H
Route of Application: Inhalation
Exposure Time: (7-20D PREG)
Result: Effects on Embryo or Fetus: Fetotoxicity (except death,
e.g., stunted fetus). Specific Developmental Abnormalities:
Other developmental abnormalities.
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Rat
Dose: 670 MG/M3/24H
Route of Application: Inhalation
Exposure Time: (15D PRE/1-22D PREG)
Result: Effects on Fertility: Female fertility index (e.g., #
females pregnant per # sperm positive females; # females
pregnant per # females mated ).
Species: Rat
Dose: 56600 UG/M3/24H
Route of Application: Inhalation
Exposure Time: (1-22D PREG)
Result: Effects on Newborn: Biochemical and metabolic.
Species: Rat
Dose: 150 PPM/24H
Route of Application: Inhalation
Exposure Time: (7-14D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
Specific Developmental Abnormalities: Musculoskeletal system.
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Species: Mouse
Dose: 12 GM/KG
Route of Application: Oral
Exposure Time: (6-15D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
Species: Mouse
Dose: 6500 MG/KG
Route of Application: Oral
Exposure Time: (8-12D PREG)
Result: Effects on Newborn: Growth statistics (e.g., reduced
weight gain).
Species: Mouse
Dose: 5 MG/KG
Route of Application: Intraperitoneal
Exposure Time: (1D MALE)
Result: Effects on Fertility: Pre-implantation mortality (e.g.,
reduction in number of implants per female; total number of
implants per corpora lutea). Effects on Embryo or Fetus: Fetal
death.
Species: Mouse
Dose: 4 GM/KG
Route of Application: Parenteral
Exposure Time: (12D PREG)
Result: Effects on Newborn: Weaning or lactation index (e.g., #
alive at weaning per # alive at day 4).
Species: Rabbit
Dose: 1 GM/M3/24H
Route of Application: Inhalation
Exposure Time: (7-20D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
Effects on Fertility: Abortion. Effects on Embryo or Fetus:
Fetal death.
Species: Rabbit
Dose: 500 PPM/7H
Route of Application: Inhalation
Exposure Time: (6-18D PREG)
Result: Maternal Effects: Other effects.
CMR CAT.: Carc. Cat.1
12 - Ecological Information
ELIMINATION
Classification: Substantially biodegradable.
ECOTOXICOLOGICAL EFFECTS
Test Type: EC50 Algae
Species: Selenastrum capricornutum resp.
Time: 72 h
Value: 29 mg/l
Test Type: EC50 Daphnia
Species: Daphnia magna
Time: 48 h
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Value: 22 mg/l
Test Type: EC50 Daphnia
Species: Daphnia magna
Time: 48 h
Value: 9.2 mg/l
Test Type: LC50 Fish
Species: Onchorhynchus mykiss (Rainbow trout)
Time: 96 h
Value: 5.9 mg/l
Test Type: LC50 Fish
Species: Pimephales promelas (Fathead minnow)
Time: 96 h
Value: 15 - 32 mg/l
Test Type: LC50 Fish
Species: Lepomis macrochirus (Bluegill)
Time: 96 h
Value: 230 mg/l
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Burn in a chemical incinerator equipped with an
afterburner and scrubber but exert extra care in igniting as this
material is highly flammable. Observe all federal, state, and
local environmental regulations.
14 - Transport Information
RID/ADR
UN#: 1114
Class: 3
PG: II
Proper Shipping Name: Benzene
IMDG
UN#: 1114
Class: 3
PG: II
Proper Shipping Name: Benzene
Marine Pollutant: No
Severe Marine Pollutant: No
IATA
UN#: 1114
Class: 3
PG: II
Proper Shipping Name: Benzene
Inhalation Packing Group I: No
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 601-020-00-8
INDICATION OF DANGER: F T
Highly Flammable. Toxic.
R-PHRASES: 45 11 48/23/24/25
May cause cancer. Highly flammable. Toxic: danger of serious
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damage to health by prolonged exposure through inhalation, in
contact with skin and if swallowed.
S-PHRASES: 53 45
Restricted to professional users. Attention - Avoid exposure -
obtain special instructions before use. In case of accident or
if you feel unwell, seek medical advice immediately (show the
label where possible).
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 3
SWITZERLAND
SWISS POISON CLASS: 1*
NORWAY
Labelling for organic solvents where the package is 1liter or
more.
YL-tall m3/l: 410666
YL-group: 5
Safety phrases: 38 42 210
In case of insufficient ventilation, wear suitable respiratory
equipment. During fumigation/spraying wear suitable respiratory
equipment. Use compressed air- or fresh air line breathing
apparatus in confined spaces.
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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