SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 30/JAN/2005
Date Updated: 30/NOV/2004
Version 1.3
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name BENZALKONIUM CHLORIDE SIGMAULTRA
Product Number B6295
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
BENZALKONIUM CHLORIDE 63449-41-2 264-151-6 612-140-00-5
Synonyms Alkyl dimethylbenzyl ammonium chloride *
Alkyldimethyl(phenylmethyl)quaternary ammonium
chlorides * Ammonyx * Arquad dmmcb-75 * Barquat
MB-50 * Bayclean * Benirol * Benzalkonium A *
Benzalkonium chloride * Bionol * Bio-quat 50-24
* Bio-quat 50-25 * Bio-quat 50-30 * Bio-quat
50-40 * Bio-quat 50-42 * Bio-quat 50-60 *
Bio-quat 50-65 * Bio-quat 80-24 * Bio-quat 80-28
* Bio-quat 80-40 * Bio-quat 80-42 * BTC * BTC 50
* BTC 65 * BTC 100 * BTC 824 * BTC 2565 * BTC
8248 * BTC 8249 * BTC E-8358 * BTC 50 USP * BTC
65 USP * Cequartyl * Culversan LC 80 * Dimanin A
* Dodigen 226 * Drapolene * Drapolex * Enuclen *
Gardiquat 1450 * Gardiquart SV480 * Genamin KDS
* Germicin * Germitol * Intexan LB-50 * Kemamine
BAC * Marinol * Mefarol * Neo Germ-I-tol * Onyx
BTC (Onyx oil & chem Co) * Osvan * Paralkan *
Pheneene germicidal solution and tincture *
Quaternary ammonium compounds,
alkylbenzyldimethyl, chlorides * Quaternium-1 *
Romergal CB * Triton K-60 * Vikrol RQ * Zephiral
* Zephiran chloride
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Harmful in contact with skin and if swallowed. Causes burns. Very
toxic to aquatic organisms.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately. Do not induce vomiting.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Carbon dioxide. Dry chemical powder. Water spray.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Ventilate
area and wash spill site after material pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe dust. Do not get in
eyes, on skin, on clothing. Avoid prolonged or repeated exposure.
STORAGE
Conditions of Storage: Keep tightly closed.
SPECIAL REQUIREMENTS: Hygroscopic.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Use only in a chemical fume hood.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Discard contaminated
SIGMA - B6295 www.sigma-aldrich.com Page 2
shoes. Wash thoroughly after handling.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Color: Faintly yellow
Form: Fine crystals
Property Value At Temperature or Pressure
pH N/A
BP/BP Range N/A
MP/MP Range N/A
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density N/A
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content < 10 %
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Conditions to Avoid: Moisture.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Nitrogen oxides, Hydrogen chloride gas.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: BO3150000
ACUTE TOXICITY
LD50
Oral
Rat
SIGMA - B6295 www.sigma-aldrich.com Page 3
240 mg/kg
Remarks: Behavioral:Somnolence (general depressed activity).
Gastrointestinal:Nausea or vomiting.
LD50
Intraperitoneal
Rat
14500 UG/KG
Remarks: Behavioral:Ataxia. Lungs, Thorax, or
Respiration:Dyspnea. Gastrointestinal:Ulceration or bleeding
from small intestine.
LD50
Subcutaneous
Rat
400 MG/KG
Remarks: Behavioral:Somnolence (general depressed activity).
LD50
Intravenous
Rat
13900 UG/KG
Remarks: Behavioral:Convulsions or effect on seizure threshold.
Lungs, Thorax, or Respiration:Dyspnea.
LD50
Subcutaneous
Mouse
64 MG/KG
Remarks: Behavioral:Somnolence (general depressed activity).
IRRITATION DATA
Skin
Human
0.15 mg
3D
I
Remarks: Mild irritation effect
Eyes
Human
0.05 mg
Remarks: Severe irritation effect
Eyes
Monkey
2 mg
24H
Remarks: Severe irritation effect
Skin
Rabbit
50 mg
24H
Remarks: Moderate irritation effect
Eyes
Rabbit
0.1 mg
Eyes
SIGMA - B6295 www.sigma-aldrich.com Page 4
Rabbit
1 mg
24H
Remarks: Severe irritation effect
Eyes
Rabbit
10 mg
Remarks: Mild irritation effect
SIGNS AND SYMPTOMS OF EXPOSURE
Inhalation may result in spasm, inflammation and edema of the
larynxand bronchi, chemical pneumonitis, and pulmonary edema.
Symptoms of exposure may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea, and
vomiting. Material is extremely destructive to tissue of the
mucous membranes and upper respiratory tract, eyes, and skin. To
the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
ROUTE OF EXPOSURE
Skin Contact: Causes burns.
Skin Absorption: Harmful if absorbed through skin.
Eye Contact: Causes burns.
Inhalation: May be harmful if inhaled. Material is extremely
destructive to the tissue of the mucous membranes and upper
respiratory tract.
Ingestion: Harmful if swallowed.
CHRONIC EXPOSURE - MUTAGEN
Hamster
1 MG/L
Cell Type: Embryo
Sister chromatid exchange
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Rat
Dose: 50 MG/KG
Route of Application: Intravaginal
Exposure Time: (1D PREG)
Result: Effects on Fertility: Litter size (e.g.; # fetuses per
litter; measured before birth). Effects on Embryo or Fetus:
Fetotoxicity (except death, e.g., stunted fetus).
Species: Rat
Dose: 100 MG/KG
Route of Application: Intravaginal
Exposure Time: (1D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
Effects on Embryo or Fetus: Fetal death.
Species: Rat
Dose: 200 MG/KG
Route of Application: Intravaginal
Exposure Time: (1D PREG)
Result: Effects on Fertility: Pre-implantation mortality (e.g.,
reduction in number of implants per female; total number of
implants per corpora lutea).
SIGMA - B6295 www.sigma-aldrich.com Page 5
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
UN#: 3261
Class: 8
PG: III
Proper Shipping Name: Corrosive solid, acidic,
organic, n.o.s.
IMDG
UN#: 3261
Class: 8
PG: III
Proper Shipping Name: CORROSIVE SOLID, ACIDIC,
ORGANIC, N.O.S.
Marine Pollutant: No
Severe Marine Pollutant: No
Technical Name: Required
IATA
UN#: 3261
Class: 8
PG: III
Proper Shipping Name: Corrosive solid, acidic,
organic, n.o.s.
Inhalation Packing Group I: No
Technical Name: Required
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 612-140-00-5
INDICATION OF DANGER: C N
Corrosive. Dangerous for the environment.
R-PHRASES: 21/22 34 50
Harmful in contact with skin and if swallowed. Causes burns.
Very toxic to aquatic organisms.
S-PHRASES: 36/37/39 45 61
Wear suitable protective clothing, gloves, and eye/face
protection. In case of accident or if you feel unwell, seek
medical advice immediately (show the label where possible).
Avoid release to the environment. Refer to special
instructions/safety data sheets.
SWITZERLAND
SWISS POISON CLASS: 3
16 - Other Information
SIGMA - B6295 www.sigma-aldrich.com Page 6
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
SIGMA - B6295 www.sigma-aldrich.com Page 7
|