SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 28/JUN/2005
Date Updated: 13/MAR/2004
Version 1.1
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name DIBUTYLAMINE, 98+%
Product Number D44952
Company Sigma-Aldrich Pty. Ltd.
12 Anella Avenue
Castle Hill NSW 2154
Australia
Technical Phone # +61 2 9841 0555 (1800 800 097)
Fax +61 2 9841 0500 (1800 800 096)
Emergency Phone # +44 8701906777 (1800 448 465)
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
DI-N-BUTYLAMINE 111-92-2 203-921-8 612-049-00-0
Formula C8H19N
Molecular Weight 129.25 AMU
Synonyms 1-Butanamine, N-butyl- * N-Butyl-1-butanamine *
Dibutilamina (Romanian) * n-Dibutylamine
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Flammable. Harmful by inhalation, in contact with skin and if
swallowed.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER EYE CONTACT
Assure adequate flushing of the eyes by separating the eyelids
with fingers.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Foam and water spray are effective but may cause
frothing. Carbon dioxide, dry chemical powder, or appropriate
foam. Use water spray to cool fire-exposed containers.
Unsuitable: Carbon Dioxide, dry chemical powder, or appropriate
foam. Water can be applied as a spray or fog and if properly
applied is capable of extinguishing the fire by sweeping the
flames off the surface of the burning liquid.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
Vapor may travel considerable distance to source of ignition and
flash back.
Explosion Hazards: Vapor may travel considerable distance to
source of ignition and flash back.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Absorb on sand or vermiculite and place in closed containers for
disposal.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Do not get
in eyes, on skin, on clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed. Keep away from heat
and open flame. Store in a cool dry place.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Use only in a chemical fume hood.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling. Wash contaminated clothing before
reuse.
EXPOSURE LIMITS - GERMANY
Source Type Value
TRGS 900 OEL 29 mg/m3
5 ppm
Remarks: =1=
Remarks: H,20,ARW
PERSONAL PROTECTIVE EQUIPMENT
Special Protective Measures: Wear appropriate government approved
respirator, chemical-resistant gloves, safety goggles, other
protective clothing.
9 - Physical and Chemical Properties
Appearance Color: Colorless
Form: Clear liquid
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Property Value At Temperature or Pressure
pH 11.1 20 掳C Concentration: 1
g/l
BP/BP Range 159 - 161 掳C
MP/MP Range -62 掳C
Flash Point 40 掳C Method: closed cup
Flammability N/A
Autoignition Temp 312 掳C
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits Lower: 1.1 %
Upper: 10 %
Vapor Pressure 1.9 mmHg 20 掳C
SG/Density 0.761 g/cm3
Partition Coefficient Log Kow: 2.83
Viscosity < 0.001 Pas 20 掳C
Vapor Density 4.46 g/l
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility Solubility in Water:Soluble.
Other Solvents: ETHANOL, ETHER, ACETONE
10 - Stability and Reactivity
STABILITY
Materials to Avoid: Strong oxidizing agents Carbon dioxide., Zinc,
Galvanized iron, Copper
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide,
and nitrogen oxides.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: HR7780000
ACUTE TOXICITY
LD50 LD50
Oral Oral
Rat Rat
189 mg/kg 189 mg/kg
LD50 LD50
Intraperitoneal Intraperitoneal
Rat Rat
110 MG/KG 110 MG/KG
LD50 LD50
Subcutaneous Subcutaneous
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Rat Rat
494 MG/KG 494 MG/KG
LD50 LD50
Oral Oral
Mouse Mouse
290 mg/kg 290 mg/kg
LD50 LD50
Intraperitoneal Intraperitoneal
Mouse Mouse
200 MG/KG 200 MG/KG
LD50 LD50
Skin Skin
Rabbit Rabbit
770 mg/kg
1010 UL/KG
LD50 LD50
Oral Oral
Guinea pig Guinea pig
230 mg/kg 230 mg/kg
IRRITATION DATA
Skin Skin
Rabbit Rabbit
500 mg 500 mg
Remarks: Open irritation test Open irritation test
SIGNS AND SYMPTOMS OF EXPOSURE
Material is extremely destructive to tissue of the mucous
membranes and upper respiratory tract, eyes, and skin.
Inhalation may result in spasm, inflammation and edema of the
larynxand bronchi, chemical pneumonitis, and pulmonary edema.
Symptoms of exposure may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea, and
vomiting. To the best of our knowledge, the chemical, physical,
and toxicological properties have not been thoroughly
investigated.
ROUTE OF EXPOSURE
Eye Contact: Can cause blindness.
Ingestion: Toxic if swallowed.
Multiple Routes: Harmful if swallowed or absorbed through skin.
Causes burns.
TARGET ORGAN INFORMATION
Eyes.
CHRONIC EXPOSURE - MUTAGEN
Hamster Hamster
200 MG/L 200 MG/L
48H 48H
Cell Type: fibroblast fibroblast
Cytogenetic analysis Cytogenetic analysis
12 - Ecological Information
ECOTOXICOLOGICAL EFFECTS
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Test Type: EC50 Daphnia
Species: Daphnia magna
Time: 24 h
Value: 124 - 205 mg/l
Test Type: EC50 Daphnia
Species: Daphnia magna
Time: 48 h
Value: 66 mg/l
Test Type: EC50 Algae
Species: Selenastrum capricornutum resp.
Time: 96 h
Value: 19 mg/l
Test Type: LC50 Fish
Species: Onchorhynchus mykiss (Rainbow trout)
Time: 96 h
Value: 5.5 - 37 mg/l
13 - Disposal Considerations
SUBSTANCE DISPOSAL
This combustible material may be burned in a chemical incinerator
equipped with an afterburner and scrubber. Observe all federal,
state, and local environmental regulations.
14 - Transport Information
RID/ADR
UN#: 2248
Class: 8
PG: II
Proper Shipping Name: Di-n-butylamine
IMDG
UN#: 2248
Class: 8
PG: II
Subrisk: 3
Proper Shipping Name: DI-(N-BUTYL)AMINE
Marine Pollutant: No
Severe Marine Pollutant: No
IATA
UN#: 2248
Class: 8
PG: II
Subrisk: 3
Proper Shipping Name: Di-n-butylamine
Inhalation Packing Group I: No
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 612-049-00-0
INDICATION OF DANGER: Xn
Harmful.
R-PHRASES: 10 20/21/22
Flammable. Harmful by inhalation, in contact with skin and if
swallowed.
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COUNTRY SPECIFIC INFORMATION
Germany
WGK: 1
SWITZERLAND
SWISS POISON CLASS: 3
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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