SIGMA-ALDRICH



                         Material Safety Data Sheet



                                               Date Printed: 16/NOV/2004

                                               Date Updated: 14/MAR/2004

                                                             Version 1.2

                                                 According to 91/155/EEC





1 - Product and Company Information



Product Name                   ANTIPAIN ~10000 U/MG

Product Number                 10791



Company                        Sigma-Aldrich Pty, Ltd

                               Unit 2, 14 Anella Avenue

                               Castle Hill NSW 1765

                               Australia

Technical Phone #              +61 2 9841 0555

Fax                            +61 2 9841 0500

Emergency Phone #              +61 2 9841 0566



2 - Composition/Information on Ingredients



Product Name                         CAS #        EC no       Annex I

                                                              Index Number

ANTIPAIN ~10000 U/MG*                37691-11-5   253-631-0   None



Formula             C27H44N10O6

Molecular Weight    604.7 AMU

Synonyms            Antipain



3 - Hazards Identification







4 - First Aid Measures





5 - Fire Fighting Measures



EXTINGUISHING MEDIA

   Suitable: Water spray. Carbon dioxide, dry chemical powder, or

   appropriate foam.



SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS

   Wear self-contained breathing apparatus and protective clothing

   to prevent contact with skin and eyes.



6 - Accidental Release Measures



METHODS FOR CLEANING UP

   Wash spill site with soap solution. Flush spill area with

   copious amounts of water. Place in appropriate container. Avoid

   raising dust.



7 - Handling and Storage



STORAGE

   Store at -20°C

8 - Exposure Controls / Personal Protection



PERSONAL PROTECTIVE EQUIPMENT

   Eye Protection: Chemical safety goggles.



9 - Physical and Chemical Properties



Appearance                Color: Yellow

                          Form: Powder



Property                  Value                At Temperature or Pressure



pH                        N/A

BP/BP Range               N/A

MP/MP Range               N/A

Flash Point               N/A

Flammability              N/A

Autoignition Temp         N/A

Oxidizing Properties      N/A

Explosive Properties      N/A

Explosion Limits          N/A

Vapor Pressure            N/A

SG/Density                N/A

Partition Coefficient     N/A

Viscosity                 N/A

Vapor Density             N/A

Saturated Vapor Conc.     N/A

Evaporation Rate          N/A

Bulk Density              N/A

Decomposition Temp.       N/A

Solvent Content           N/A

Water Content             N/A

Surface Tension           N/A

Conductivity              N/A

Miscellaneous Data        N/A

Solubility                N/A



10 - Stability and Reactivity



HAZARDOUS DECOMPOSITION PRODUCTS

   Hazardous Decomposition Products: Thermal decomposition may

   produce carbon monoxide, carbon dioxide, and nitrogen oxides.



HAZARDOUS EXOTHERMIC REACTIONS

   Hazardous Exothermic Reactions: Will not occur



11 - Toxicological Information



RTECS NUMBER: YV9350700



ACUTE TOXICITY



   LD50

   Oral

   Mouse

   > 500 mg/kg



   LD50

   Subcutaneous

   Mouse

   >500 MG/KG







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   LD50

   Intravenous

   Mouse

   187 MG/KG



CHRONIC EXPOSURE - TERATOGEN



   Species: Rat

   Dose: 4838 MG/KG

   Route of Application: Intrauterine

   Exposure Time: (5D PREG)

   Result: Effects on Embryo or Fetus: Fetotoxicity (except death,

   e.g., stunted fetus).



CHRONIC EXPOSURE - REPRODUCTIVE HAZARD



   Species: Monkey

   Dose: 3600 UG/KG

   Route of Application: Intravaginal

   Exposure Time: (1D PRE)

   Result: Effects on Fertility: Mating performance (e.g., # sperm

   positive females per # females mated; # copulations per # estrus

   cycles).



12 - Ecological Information



No data available.



13 - Disposal Considerations



SUBSTANCE DISPOSAL

   Dissolve or mix the material with a combustible solvent and burn

   in a chemical incinerator equipped with an afterburner and

   scrubber. Observe all federal, state, and local environmental

   regulations.



14 - Transport Information



RID/ADR

   Non-hazardous for road transport.



IMDG

   Non-hazardous for sea transport.



IATA

   Non-hazardous for air transport.



15 - Regulatory Information





16 - Other Information



WARRANTY

   The above information is believed to be correct but does not

   purport to be all inclusive and shall be used only as a guide. The

   information in this document is based on the present state of our

   knowledge and is applicable to the product with regard to

   appropriate safety precautions. It does not represent any

   guarantee of the properties of the product. Sigma-Aldrich Inc.,

   shall not be held liable for any damage resulting from handling or

   from contact with the above product. See reverse side of invoice

   or packing slip for additional terms and conditions of sale.





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   Copyright 2004 Sigma-Aldrich Co. License granted to make unlimited

   paper copies for internal use only.



DISCLAIMER

   For R&D use only. Not for drug, household or other uses.









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