SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 16/NOV/2004
Date Updated: 12/MAR/2004
Version 1.2
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name ANTIMONY(III) OXIDE, 99.99%
Product Number 379255
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
ANTIMONY (III) OXIDE 1309-64-4 215-175-0 051-005-00-X
Formula Sb2O3
Molecular Weight 291.5 AMU
Synonyms A 1582 * A 1588LP * Amspec-KR * Antimonious
oxide * Antimony(3+) oxide * Antimony
sesquioxide * Antimony trioxide * Antimony
trioxide production (ACGIH) * Antimony White *
Antox * AP 50 * AT 3 (fireproofing agent) * Atox
F * Atox S * Chemetron fire shield * C.I. 77052
* C.I. Pigment White 11 * Dechlorane A-O *
Diantimony trioxide * Exitelite * Fireshield
FSPO 405 * Flowers of antimony * NCI-C55152 *
Nyacol A 1530 * Nyacol A 1510LP * Patox C *
Patox H * Patox L * Patox M * Patox S * Stibiox
MS * Thermoguard B * Thermoguard L * Thermoguard
S * Timonox * Timonox White Star * Twinkling
star * Weisspiessglanz (German) * White star
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Limited evidence of a carcinogenic effect.
Carc. Cat.3
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If breathing becomes difficult,
call a physician.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves. Wear disposable coveralls and discard them after
use.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe dust. Do not get in
eyes, on skin, on clothing. Avoid prolonged or repeated exposure.
STORAGE
Conditions of Storage: Keep tightly closed.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Use only in a chemical fume hood. Safety shower and eye bath.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Wash thoroughly after
handling.
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 0.5 mg/m3
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EXPOSURE LIMITS - GERMANY
Source Type Value
TRGS 900 OEL 0.3 mg/m3, E
Remarks: 4
Remarks: 25,TRGS 901-22
EXPOSURE LIMITS - SWITZERLAND
Source Type Value
OEL OEL 0.1 mg/m3
Remarks: E K
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL TWA 0.5MG(SB)/M3
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator in
nonventilated areas and/or for exposure above the TLV or PEL.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Solid
Property Value At Temperature or Pressure
pH N/A
BP/BP Range N/A
MP/MP Range 655 掳C
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density 5.2 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Nature of decomposition products
not known.
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HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: CC5650000
ACUTE TOXICITY
LD50
Oral
Rat
> 34600 mg/kg
Remarks: Behavioral:Somnolence (general depressed activity).
Skin and Appendages: Other: Hair.
LD50
Intraperitoneal
Rat
3250 MG/KG
LD50
Subcutaneous
Rat
7904 MG/KG
LD50
Intraperitoneal
Mouse
172 MG/KG
IRRITATION DATA
Eyes
Rabbit
100 mg
Remarks: Mild irritation effect
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: Material may be irritating to mucous membranes and
upper respiratory tract. May be harmful if inhaled.
Ingestion: May be harmful if swallowed.
CHRONIC EXPOSURE - CARCINOGEN
Result: This product is or contains a component that has been
reported to be possibly carcinogenic based on its IARC, ACGIH,
NTP, or EPA classification.
Rat
Route of Application: Inhalation
Exposure Time: 52W-
Result: Tumorigenic:Carcinogenic by RTECS criteria. Lungs,
Thorax, or Respiration:Tumors. Liver:Tumors.
Rat
Route of Application: Inhalation
Exposure Time: 1Y-
Result: Tumorigenic:Equivocal tumorigenic agent by RTECS
criteria. Lungs, Thorax, or Respiration:Tumors. Liver:Tumors.
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Rat
Route of Application: Inhalation
Exposure Time: 52W-
Result: Tumorigenic:Neoplastic by RTECS criteria. Liver:Tumors.
Skin and Appendages: Other: Tumors.
Rat
Route of Application: Inhalation
Exposure Time: 7H/52W-
Result: Tumorigenic:Carcinogenic by RTECS criteria. Lungs,
Thorax, or Respiration:Tumors.
IARC CARCINOGEN LIST
Rating: Group 2B
CHRONIC EXPOSURE - MUTAGEN
Human
50 MG/L
Cell Type: lymphocyte
Cytogenetic analysis
Hamster
90 UG/L
Cell Type: lung
Sister chromatid exchange
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Rat
Dose: 270 UG/M3
Route of Application: Inhalation
Exposure Time: (1-21D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
Effects on Embryo or Fetus: Fetal death.
Species: Rat
Dose: 82 UG/M3
Route of Application: Inhalation
Exposure Time: (1-21D PREG)
Result: Effects on Fertility: Pre-implantation mortality (e.g.,
reduction in number of implants per female; total number of
implants per corpora lutea). Effects on Embryo or Fetus:
Fetotoxicity (except death, e.g., stunted fetus).
Species: Rat
Dose: 270 UG/M3/24H
Route of Application: Inhalation
Exposure Time: (1-21D PREG)
Result: Effects on Fertility: Pre-implantation mortality (e.g.,
reduction in number of implants per female; total number of
implants per corpora lutea). Effects on Fertility:
Post-implantation mortality (e.g., dead and/or resorbed implants
per total number of implants). Effects on Embryo or Fetus: Fetal
death.
Species: Rat
Dose: 23320 UG/KG
Route of Application: Intratesticular
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Exposure Time: (1D MALE)
Result: Paternal Effects: Spermatogenesis (including genetic
material, sperm morphology,motility, and count). Paternal
Effects: Testes, epididymis, sperm duct.
CMR CAT.: Carc. Cat.3
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
Non-hazardous for road transport.
IMDG
Non-hazardous for sea transport.
IATA
Non-hazardous for air transport.
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 051-005-00-X
INDICATION OF DANGER: Xn
Harmful.
R-PHRASES: 40
Limited evidence of a carcinogenic effect.
S-PHRASES: 22 36/37
Do not breathe dust. Wear suitable protective clothing and
gloves.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 2
SWITZERLAND
SWISS POISON CLASS: 4
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2004 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
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DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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