SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 16/NOV/2005
Date Updated: 28/OCT/2005
Version 1.10
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name POTASSIUM ANTIMONYL TARTRATE
TRIHYDRATE, 99+%, A.C.S. REAGENT
Product Number 383376
Company Sigma-Aldrich Pty. Ltd.
12 Anella Avenue
Castle Hill NSW 2154
Australia
Technical Phone # +61 2 9841 0555 (1800 800 097)
Fax +61 2 9841 0500 (1800 800 096)
Emergency Phone # +44 8701906777 (1800 448 465)
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
POTASSIUM ANTIMONY TARTRATE 28300-74-5 234-293-3 051-003-00-9
TRIHYDRATE
Formula C8H4K2O12Sb2.3H2O
Molecular Weight 667.9 AMU
Synonyms Antimonate(2)-, bis(mu-tartrato(4-))di-,
dipotassium, trihydrate * Emetique (French) *
ENT 50,434 * Potassium antimonyl tartrate
trihydrate * Tartar emetic * Tartaric acid,
antimony potassium salt, trihydrat * Tartarized
antimony * Tartox * Tartrate
antimonio-potassique (French) * Tartrated
antimony
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Harmful by inhalation and if swallowed. Toxic to aquatic
organisms, may cause long-term adverse effects in the aquatic
environment.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe dust. Do not get in
eyes, on skin, on clothing. Avoid prolonged or repeated exposure.
STORAGE
Conditions of Storage: Keep tightly closed.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Use only in a chemical fume hood. Safety shower and eye bath.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Wash thoroughly after
handling.
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 0.5 mg/m3
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL TWA 0.5MG(SB)/M3
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PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Solid
Color: White
Form: Powder
Property Value At Temperature or Pressure
pH 4 20 掳C
BP/BP Range N/A
MP/MP Range N/A
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density 2.6 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density 1.3 kg/l
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility Solubility in Water:Soluble.
Other Solvents: SOLUBLE IN WATER, GLYCEROL
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents, Silver salts, Lead,
Carbonates, Strong bases, Mineral acids.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Potassium oxides, Antimony/antimony oxides.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: CC6825000
ACUTE TOXICITY
LDLO
Oral
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Human
2 mg/kg
LDLO
Intravenous
Man
12 MG/KG
1W-I
Remarks: Kidney, Ureter, Bladder:Other changes. Liver:Other
changes.
LD50
Intravenous
Man
249 MG/KG
9D-I
Remarks: Behavioral:Hallucinations, distorted perceptions.
Nutritional and Gross Metabolic:Changes in:Body temperature
increase. Gastrointestinal:Nausea or vomiting.
LD50
Oral
Rat
115 mg/kg
LD50
Intraperitoneal
Rat
11 MG/KG
LD50
Intraperitoneal
Mouse
33 MG/KG
LD50
Subcutaneous
Mouse
55 MG/KG
Remarks: Lungs, Thorax, or Respiration:Dyspnea.
Behavioral:Muscle weakness.
LD50
Intravenous
Mouse
45 MG/KG
LD50
Oral
Rabbit
115 mg/kg
LD50
Intravenous
Rabbit
12 MG/KG
LD50
Intraperitoneal
Guinea pig
15 MG/KG
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SIGNS AND SYMPTOMS OF EXPOSURE
Gastrointestinal disturbances. Headache. Dizziness. Weakness.
Damage to the kidneys. Potassium antimony tartrate is the most
potent trivalent antimony compound. Trivalent antimony compounds
are more toxic than the pentavalent because they are excreted
slowly. The most serious adverse effects are on the heart and
liver along with coughing, chest and abdominal pain, vomiting,
fainting, and collapse. Less immediate adverse effects include:
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: May be harmful if inhaled. Material may be
irritating to mucous membranes and upper respiratory tract.
Ingestion: Toxic if swallowed.
TARGET ORGAN INFORMATION
Liver. Kidneys. Heart.
CHRONIC EXPOSURE - MUTAGEN
Human
100 UMOL/L
Cell Type: fibroblast
Cytogenetic analysis
Rat
2 MG/KG
Intraperitoneal
Cytogenetic analysis
12 - Ecological Information
ECOTOXICOLOGICAL EFFECTS
Test Type: EC50 Daphnia
Species: Daphnia magna
Time: 48 h
Value: 5 mg/l
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
UN#: 1551
Class: 6.1
PG: III
Proper Shipping Name: Antimony potassium tartrate
IMDG
UN#: 1551
Class: 6.1
PG: III
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Proper Shipping Name: Antimony potassium tartrate
Marine Pollutant: No
Severe Marine Pollutant: No
IATA
UN#: 1551
Class: 6.1
PG: III
Proper Shipping Name: Antimony potassium tartrate
Inhalation Packing Group I: No
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 051-003-00-9
NOTA: A, 1
INDICATION OF DANGER: Xn-N
Harmful. Dangerous for the environment.
R-PHRASES: 20/22-51/53
Harmful by inhalation and if swallowed. Toxic to aquatic
organisms, may cause long-term adverse effects in the aquatic
environment.
S-PHRASES: 61
Avoid release to the environment. Refer to special
instructions/safety data sheets.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 3 (Self classification)
SWITZERLAND
SWISS POISON CLASS: 2
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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