SIGMA-ALDRICH
Material Safety Data Sheet
Version 3.3
Revision Date 09/11/2008
Print Date 10/19/2008
1. PRODUCT AND COMPANY IDENTIFICATION
Product name : Acetaldehyde
Product Number : 402788
Brand : Sigma-Aldrich
Company : Sigma-Aldrich
3050 Spruce Street
SAINT LOUIS MO 63103
USA
Telephone : +1 800-325-5832
Fax : +1 800-325-5052
Emergency Phone # : (314) 776-6555
2. COMPOSITION/INFORMATION ON INGREDIENTS
Synonyms : Ethanal
Formula : C2H4O
Molecular Weight : 44.05 g/mol
CAS-No. EC-No. Index-No. Concentration
Acetaldehyde
75-07-0 200-836-8 605-003-00-6 -
3. HAZARDS IDENTIFICATION
Emergency Overview
OSHA Hazards
Flammable Liquid, Target Organ Effect, Harmful by ingestion., Skin sensitizer, Irritant, Carcinogen
Target Organs
Blood, Kidney, Lungs, Cardiovascular system., Liver, Central nervous system
HMIS Classification
Health Hazard: 2
Chronic Health Hazard: *
Flammability: 4
Physical hazards: 2
NFPA Rating
Health Hazard: 2
Fire: 4
Reactivity Hazard: 2
Potential Health Effects
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May be harmful if inhaled. Causes respiratory tract irritation.
Inhalation
May be harmful if absorbed through skin. Causes skin irritation.
Skin
Causes eye irritation.
Eyes
Harmful if swallowed.
Ingestion
4. FIRST AID MEASURES
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.Move out of dangerous area.
If inhaled
If breathed in, move person into fresh air. If not breathing give artificial respiration Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult
a physician.
5. FIRE-FIGHTING MEASURES
Flammable properties
Flash point -40 癈 (-40 癋) - closed cup
Ignition temperature 175 癈 (347 癋)
Suitable extinguishing media
For small (incipient) fires, use media such as "alcohol" foam, dry chemical, or carbon dioxide. For large fires, apply
water from as far as possible. Use very large quantities (flooding) of water applied as a mist or spray; solid streams of
water may be ineffective. Cool all affected containers with flooding quantities of water.
Specific hazards
May explode when heated. Closed containers may rupture and explode during runaway polymerization. Beware of
vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas.
Special protective equipment for fire-fighters
Wear self contained breathing apparatus for fire fighting if necessary.
Further information
Use water spray to cool unopened containers.
6. ACCIDENTAL RELEASE MEASURES
Personal precautions
Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Remove all
sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive
concentrations. Vapours can accumulate in low areas.
Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Methods for cleaning up
Contain spillage, and then collect with non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth,
vermiculite) and place in container for disposal according to local / national regulations (see section 13).
7. HANDLING AND STORAGE
Handling
Avoid contact with skin and eyes. Avoid inhalation of vapour or mist.
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Use explosion-proof equipment. Keep away from sources of ignition - No smoking. Take measures to prevent the
build up of electrostatic charge.
Storage
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully
resealed and kept upright to prevent leakage. Store in cool place.
Recommended storage temperature: 2 - 8 癈
Store under inert gas. Air sensitive.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Components with workplace control parameters
Components CAS-No. Value Control Update Basis
parameters
Acetaldehyde 75-07-0 CEIL 25 ppm 1994-09-01 US. American Conference
45 mg/m3 of Governmental and
Industrial Hygienists
Threshold Limit Values for
Chemical Substances in the
Work Environment; Annual
Reports for the Year
2004:Committees on
Threshold Limit Values
(TLVs ) and Biological
Exposure Indices (BEIs)
Remarks Confirmed animal carcinogen with unknown relevance to humans.
Substances for which the TLV is higher than the OSHA Permissible Exposure Limit
(PEL) and/or the NIOSH Recommended Exposure Limit (REL). See CFR 58(124)
:36338-33351, June 30, 1993, for revised OSHA PEL.
Substance identified by other sources as a suspected or confirmed human carcinogen.
Refers to Appendix A -- Carcinogens.
TWA 100 ppm 1989-03-01 US. Department of Labor -
180 mg/m3 Occupational Safety and
Health Administration
(OSHA) 29 CFR 1910.1000
Z-1-A
STEL 150 ppm 1989-03-01 US. Department of Labor -
270 mg/m3 Occupational Safety and
Health Administration
(OSHA) 29 CFR 1910.1000
Z-1-A
TWA 200 ppm 1993-06-30 US. Department of Labor -
360 mg/m3 Occupational Safety and
Health Administration
(OSHA) Permissible
Exposure Limits (PEL) 29
CFR 1910.1000 Air
Contaminants.
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Personal protective equipment
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multi-
purpose combination (US) or type AXBEK (EN 14387) respirator cartridges as a backup to engineering controls. If
the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and
components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Hand protection
Handle with gloves.
Eye protection
Safety glasses
Skin and body protection
Choose body protection according to the amount and concentration of the dangerous substance at the work
place.
Hygiene measures
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end
of workday.
9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance
Form liquid, clear
Colour colourless
Safety data
pH no data available
Melting point -125 癈 (-193 癋)
Boiling point 21 癈 (70 癋) at 1,013 hPa (760 mmHg)
Flash point -40 癈 (-40 癋) - closed cup
Ignition temperature 175 癈 (347 癋)
Lower explosion limit 4 %(V)
Upper explosion limit 60 %(V)
Vapour pressure 1,008.5 hPa (756.4 mmHg) at 20 癈 (68 癋)
1,451 hPa (1,088 mmHg) at 30 癈 (86 癋)
2,660 hPa (1,995 mmHg) at 55 癈 (131 癋)
Density 0.785 g/cm3
Water solubility completely miscible
Partition coefficient: log Pow: 0.5
n-octanol/water
Relative vapour 1.52
density - (Air = 1.0)
10. STABILITY AND REACTIVITY
Storage stability
Stable under recommended storage conditions.
Conditions to avoid
Air
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Heat, flames and sparks.
Materials to avoid
Oxidizing agents, Reducing agents, acids, Nitric acid, Peroxides, Bases, Sodium Hydroxide, Amines, Ammonia,
Oxygen, Warning: acetaldehyde is oxidized rapidly and exothermically by air, to acetic acid, Acid anhydrides,
Alcohols, Halogens, Ketones, Phenol, Hydrogen cyanide (hydrocyanic acid)
Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides
Hazardous reactions
Vapours may form explosive mixture with air.
11. TOXICOLOGICAL INFORMATION
Acute toxicity
LD50 Oral - rat - 661 mg/kg
Remarks: Peripheral Nerve and Sensation:Spastic paralysis with or without sensory change. Behavioral:Altered
sleep time (including change in righting reflex). Lungs, Thorax, or Respiration:Dyspnea.
LC50 Inhalation - rat - 4 h - 13300 ppm
Remarks: Behavioral:Excitement. Lungs, Thorax, or Respiration:Dyspnea.
LD50 Dermal - rabbit - 3,540 mg/kg
Irritation and corrosion
Skin - rabbit - Mild skin irritation
Eyes - rabbit - Severe eye irritation
Sensitisation
May cause allergic skin reaction.
Chronic exposure
This product is or contains a component that has been reported to be possibly carcinogenic based on its IARC,
ACGIH, NTP, or EPA classification.
IARC: Group 2B - The agent (mixture) is possibly carcinogenic to humans. (Acetaldehyde)
NTP: Reasonably anticipated to be human carcinogens. (Acetaldehyde)
OSHA: No component of this product present at levels greater than or equal to 0.1% is identified as
a carcinogen or potential carcinogen by OSHA.
Laboratory experiments have shown mutagenic effects.
Signs and Symptoms of Exposure
Blurred vision, Unconsciousness
Potential Health Effects
May be harmful if inhaled. Causes respiratory tract irritation.
Inhalation
May be harmful if absorbed through skin. Causes skin irritation.
Skin
Causes eye irritation.
Eyes
Harmful if swallowed.
Ingestion
Blood, Kidney, Lungs, Cardiovascular system., Liver, Central nervous system,
Target Organs
Additional Information
RTECS: AB1925000
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12. ECOLOGICAL INFORMATION
Elimination information (persistence and degradability)
no data available
Ecotoxicity effects
Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 31 mg/l - 96 h
LC100 - Leuciscus idus (Golden orfe) - 124 - 156 mg/l - 48 h
Toxicity to daphnia EC50 - Daphnia magna (Water flea) - 48 mg/l - 48 h
and other aquatic
invertebrates.
Further information on ecology
no data available
13. DISPOSAL CONSIDERATIONS
Product
Burn in a chemical incinerator equipped with an afterburner and scrubber but exert extra care in igniting as this
material is highly flammable. Observe all federal, state, and local environmental regulations. Contact a licensed
professional waste disposal service to dispose of this material.
Contaminated packaging
Dispose of as unused product.
14. TRANSPORT INFORMATION
DOT (US)
UN-Number: 1089 Class: 3 Packing group: I
Proper shipping name: Acetaldehyde
Marine pollutant: No
Poison Inhalation Hazard: No
IMDG
UN-Number: 1089 Class: 3 Packing group: I EMS-No: F-E, S-D
Proper shipping name: ACETALDEHYDE
Marine pollutant: No
IATA
UN-Number: 1089 Class: 3 Packing group: I
Proper shipping name: Acetaldehyde
IATA Passenger: Not permitted for transport
15. REGULATORY INFORMATION
OSHA Hazards
Flammable Liquid, Target Organ Effect, Harmful by ingestion., Skin sensitizer, Irritant, Carcinogen
DSL Status
All components of this product are on the Canadian DSL list.
SARA 302 Components
SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 313 Components
CAS-No. Revision Date
Acetaldehyde 75-07-0 1987-01-01
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SARA 311/312 Hazards
Fire Hazard, Acute Health Hazard, Chronic Health Hazard
Massachusetts Right To Know Components
CAS-No. Revision Date
Acetaldehyde 75-07-0 1987-01-01
Pennsylvania Right To Know Components
CAS-No. Revision Date
Acetaldehyde 75-07-0 1987-01-01
New Jersey Right To Know Components
CAS-No. Revision Date
Acetaldehyde 75-07-0 1987-01-01
California Prop. 65 Components
WARNING! This product contains a chemical known in the State of CAS-No. Revision Date
California to cause cancer. 75-07-0 1992-11-09
Acetaldehyde
16. OTHER INFORMATION
Further information
Copyright 2008 Sigma-Aldrich Co. License granted to make unlimited paper copies for internal use only.
The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a
guide. The information in this document is based on the present state of our knowledge and is applicable to the
product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the
product. Sigma-Aldrich Co., shall not be held liable for any damage resulting from handling or from contact with
the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale.
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