MATERIAL SAFETY DATA SHEET
1. IDENTIFICATION OF THE SUBSTANCE/ PREPARATION AND OF THE COMPANY/UNDERTAKING
Trade Name: 3E-Zyme
Intended use: Enzymatic detergent for cleaning re-usable medical instruments and devices.
Manufacturer: Medisafe UK Limited
Marketing Address: Twyford Road Australian Supplier
Bishop's Stortford In Vitro Technologies Pty. Ltd.
Herts. CM23 3LJ UK Street/P.O.Box: 7-9 Summit Road
Country code/Postal code/Town/City: Noble Park, Melbourne, VIC 3174
Tel: +44 (0)1279 461641 Telephone / Telefax: +61397713700 / +61397713720
Fax: +44 (0)1279 461643
Emergency information: Poisons Information Centre: Tel. 131126
E-mail: info@medisafe.uk.com
Website: www.medisafe.uk.com
2. COMPOSITION/INFORMATION ON INGREDIENTS
Product Type: The product is a pH-neutral aqueous concentrate of protease, lipase and amylase
enzymes together with 2-propanol, propylene glycol, stabilisers, corrosion inhibitor and
surfactants. It is intended be used at concentrations between 0.3?.0% in water at
temperatures between 40-45 篊.
Major Ingredients:
Compound Concentration OEL R-Phrases Hazard Class CAS EINECS
2-propanol <15% LD50 (rat) R11, R36, R67 F, Xi 67-63-0 200-661-7
5000mg/kg
Propylene glycol <15% N/A N/A N/A 57-55-6 200-338-0
Distilled water ~70% N/A N/A N/A
3. HAZARDS IDENTIFICATION
Skin: May cause degreasing and redness of the skin on repeated contact.
Not significantly harmful by skin absorption.
Eyes: May cause discomfort or irritation on contact with the eye.
Respiratory: Repeated inhalation of spray or mist may cause an allergic reaction in susceptible
persons.
Ingestion: Accidental ingestion may cause slight gastric discomfort.
4. FIRST-AID MEASURES
Skin: Wash the affected area with soap and water.
Eyes: Irrigate with fresh water for 10 minutes. If discomfort continues, seek immediate medical
advice
Respiratory: Remove to fresh air. If symptoms continue, seek immediate medical advice.
Ingestion: Irrigate the mouth and throat with water. Give milk or water to drink. DO NOT induce
vomiting.
5. FIRE-FIGHTING MEASURES
Extinguishing Media: All are suitable ?Water, CO2, Foam, Dry Powder
Hazardous By-products: The product does not pose any special fire hazard.
No specific hazardous by-products.
The product is wholly miscible with water.
Special Measures: No special measures are indicated.
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MATERIAL SAFETY DATA SHEET
6. ACCIDENTAL RELEASE MEASURES
Personal Protection: Wear rubber gloves, apron and boots.
Clean up methods: Absorb into any inert absorbent material, and dispose of as clinical waste.
Environmental Measures: Although the product is wholly biodegradable, measures should be taken to prevent
discharge to groundwater.
7. HANDLING & STORAGE
Handling: Observe the instructions on the product label.
Keep away from children.
Do not mix with other chemicals
Storage: Store in dry place not below 5篊 or above 38篊 and out of direct sunlight.
Keep away from foodstuffs.
Recap bottles after use.
Large quantities should be stored in a bund if there is the potential to contaminate
groundwater.
Specific Uses: No special requirements
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Indicative Limits: 2-propanol: EH40 OEL 400 ppm (8-hour TWA)
Personal Protection: Follow the measures below when using the product in non-automated cleaning
operations.
Skin: Wear nitrile, neoprene or PVC rubber gloves
Wash hands thoroughly with soap and water after handling the product.
Eye: Wear safety goggles or visor.
Provide eyewash facilities in the workplace.
Respiratory: Avoid formation of aerosols.
Provide a well-ventilated workplace or LEV in manual cleaning operations.
Persons sensitised to biological washing powders or suffering from asthma should not
use the product.
Do not smoke when using the product.
Ingestion: Do not eat or drink when using the product.
9. PHYSICAL & CHEMICAL PROPERTIES
Appearance: Clear blue liquid.
Odour: Faint odour of screen wash.
pH: 6.5 to 7.5 (neutral).
Boiling Point: 110 篊.
Freezing Point: -20 篊.
Flammability: Not flammable.
Explosion: Not explosive.
Oxidising/Reducing: Not an oxidant or reductant.
Vapour Pressure: As water.
Relative Density: 1.01 at 25篊.
Solubility: Soluble in water in all proportions.
Evaporation Rate As water.
Special Properties: None.
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MATERIAL SAFETY DATA SHEET
10. STABILITY & REACTIVITY
Stability: Stable.
Conditions to Avoid: Do not allow to freeze.
Materials to Avoid: Oxidising agents.
Hazardous polymerisation: Will not occur.
Decomposition Products: Water, carbon monoxide, carbon dioxide when exposed to fire.
11. TOXICOLOGICAL INFORMATION
Acute:
Oral Toxicity: 2-propanol: LD50 (rat) 5000mg/kg
Propylene glycol: LD50 (rat) 22000mg/kg
Inhalation: 2-propanol: LC50 (8-hour; rat) 51mg/l
Propylene glycol: No data (low volatility)
Dermal Toxicity: 2-propanol: LD50 (rat) 12900mg/kg
Propylene glycol: LD50 (rat) 20800mg/kg
Skin Irritation (OECD TG404): 2-propanol: Not irritating
Propylene glycol: Not irritating
Eye Irritation (OECD TG405): 2-propanol: Irritant
Propylene glycol: Not irritating
Skin Sensitisation (Draize): 2-propanol: Not sensitising
Propylene glycol: Not sensitising
Chronic:
None of the ingredients are classifiable as carcinogenic, mutagenic, teratogenic, or endocrine disruptive.
12. ECOLOGICAL INFORMATION
Ecotoxicity:
Fish (OECD TG203): 2-propanol LC50 (96-hour) 9640 mg/l
Propylene glycol LC50 (96-hour) 49500 mg/l
Daphnia magna 2-propanol EC50 (24-hour) >10000 mg/l
Propylene glycol EC50 (24-hour) 43500 mg/l
Algae (OECD TG202) 2-propanol Toxicity Threshold 1050 mg/l
Propylene glycol LC
Mobility: 2-propanol Fugacity level I
Propylene glycol Fugacity level III
Persistence & Degradability: 2-propanol BOD (5-day) 49%
Propylene glycol BOD (10-day) 80%
Bioaccumulation Potential: 2-propanol BCF = 1
Propylene glycol BCF<1
Other Adverse Effects: None known.
The product does not contain any substances classifiable as ozone depleting.
The product does not contain any substances of animal origin.
Based on the available data the product exhibits low ecotoxity, is wholly biodegradable, and has no potential for
bioaccumulation.
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13. DISPOSAL CONSIDERATIONS
Product: Neat product that cannot be used or re-cycled for re-use should be disposed of as
hazardous waste through a registered waste contractor. It must not be discharged into
groundwater drains or the foul sewer.
Contaminated product should be disposed of as clinical waste.
Packaging Both the primary and secondary packaging are recyclable.
Contaminated packaging should be disposed of as clinical waste.
14. TRANSPORT INFORMATION
Road/Rail Non-hazardous
Sea IMDG Non-hazardous
Air ICAO Non-hazardous
15. REGULATORY INFORMATION
Classification: The product is not classifiable as hazardous
Safety Phrases: S2 Keep out of the reach of children
S24/25 Avoid contact with skin and eyes
S50 Do not mix with other chemicals
16. OTHER INFORMATION
Risk Phrases:
The following relate to the ingredients stated in Section 2 and not to the formulated product.
R11 Highly flammable
R36 Irritating to eyes
R67 Vapours may cause drowsiness and dizziness
Revision History:
Replaces Issue 3 published December 2006 ?Disposal Considerations clarified
Disclaimer:
This Material Safety Data Sheet is not a technical specification and does not guarantee any properties or
performance. It has been published for the purpose of giving guidance to the user in the safe storage, use and
disposal of the product, and conforms to Regulation 6 of the Chemicals (Hazardous Information and Packaging
for Supply) Regulations 2002 (CHIP 3) - Third Edition.
The information and recommendations contained herein are, to the best of our knowledge and belief, accurate at
the date of publication. Medisafe UK Ltd assumes no liability for any injury and damage resulting from the use
of the product in conditions or applications of use other than as instructed or recommended by us.
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