Material Safety Data Sheet

                                          Urea



ACC# 24680



      Section 1 - Chemical Product and Company Identification



MSDS Name: Urea

Catalog Numbers: AC424580050, S71220, S79871, A4321285, A4321286, A4922551,

A4922553, A4922556, A4922601, A4922603, A4922605, A4922608, BP169-10, BP169-

212, BP169-500, BP1690LC, NC9772669, NC9915662, U0150, U0155, U15-10, U15-3,

U15-50, U15-500, U16-10, U16-3, U16-50, U16PD40KG, U16SAM1, U1712, U1721,

U17212, U17SAM1, XXU16PD190LB, XXU16PD40KG

Synonyms: Carbamide resin; Carbamimidic acid; Carbonyl diamide; Carbonyldiamine;

Isourea

Company Identification:

         Fisher Scientific

         1 Reagent Lane

         Fair Lawn, NJ 07410

For information, call: 201-796-7100

Emergency Number: 201-796-7100

For CHEMTREC assistance, call: 800-424-9300

For International CHEMTREC assistance, call: 703-527-3887





         Section 2 - Composition, Information on Ingredients



      CAS#                   Chemical Name                  Percent      EINECS/ELINCS

     57-13-6     Urea                                       ca. 100         200-315-5



Hazard Symbols: None listed.

Risk Phrases: None listed.





                        Section 3 - Hazards Identification



                               EMERGENCY OVERVIEW



Appearance: white crystals. Causes eye and skin irritation. Causes digestive and

respiratory tract irritation. May cause cardiac disturbances. Warning! Reproductively

active.

Target Organs: Blood, cardiovascular system.

Potential Health Effects

Eye: Causes eye irritation.

Skin: Causes skin irritation.

Ingestion: Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May

cause cardiac disturbances. May cause disturbed blood electrolyte balance.

Inhalation: Inhalation of dust causes irritation of the nose and throat, coughing and

sneezing.

Chronic: Prolonged or repeated exposure may cause adverse reproductive effects.

Laboratory experiments have resulted in mutagenic effects. Prolonged exposure or

exposure to high concentrations may cause eye damage.





                         Section 4 - First Aid Measures



Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally

lifting the upper and lower eyelids. Get medical aid.

Skin: Get medical aid. Immediately flush skin with plenty of water for at least 15 minutes

while removing contaminated clothing and shoes. Wash clothing before reuse.

Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of

milk or water. Never give anything by mouth to an unconscious person. Get medical aid.

Inhalation: Remove from exposure and move to fresh air immediately. If not breathing,

give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Notes to Physician: Treat symptomatically and supportively. Weak acids such as acetic

acid and propionic acid can be used as chemical antidotes, demulcents and stimulants.





                      Section 5 - Fire Fighting Measures



General Information: During a fire, irritating and highly toxic gases may be generated

by thermal decomposition or combustion. Wear appropriate protective clothing to prevent

contact with skin and eyes. Wear a self-contained breathing apparatus (SCBA) to prevent

contact with thermal decomposition products.

Extinguishing Media: Substance is noncombustible; use agent most appropriate to

extinguish surrounding fire. Use water spray, dry chemical, carbon dioxide, or

appropriate foam.

Flash Point: Not applicable.

Autoignition Temperature: Not applicable.

Explosion Limits, Lower:Not available.

Upper: Not available.

NFPA Rating: (estimated) Health: 1; Flammability: 0; Instability: 0





                  Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section

8.

Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container.

Clean up spills immediately, observing precautions in the Protective Equipment section.

Avoid generating dusty conditions. Provide ventilation.





                      Section 7 - Handling and Storage



Handling: Wash thoroughly after handling. Remove contaminated clothing and wash

before reuse. Use with adequate ventilation. Minimize dust generation and accumulation.

Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing.

Keep container tightly closed. Avoid ingestion and inhalation.

Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area

away from incompatible substances.





           Section 8 - Exposure Controls, Personal Protection



Engineering Controls: Facilities storing or utilizing this material should be equipped

with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne

concentrations low.

Exposure Limits

   Chemical Name               ACGIH                NIOSH            OSHA - Final PELs

         Urea         none listed                  none listed           none listed



OSHA Vacated PELs: Urea: No OSHA Vacated PELs are listed for this chemical.

Personal Protective Equipment

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by

OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard

EN166.

Skin: Wear appropriate protective gloves to prevent skin exposure.

Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and

ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever

workplace conditions warrant a respirator's use.





                Section 9 - Physical and Chemical Properties



Physical State: Crystals

Appearance: white

Odor: ammonia-like

pH: 7.2 (10% solution)

Vapor Pressure: 1.2105 mm Hg @ 25C

Vapor Density: 2.07

Evaporation Rate:Not available.

Viscosity: Not available.

Boiling Point: decomposes

Freezing/Melting Point:132 deg C

Decomposition Temperature:Not available.

Solubility: Soluble.

Specific Gravity/Density:1.335

Molecular Formula:CH4N2O

Molecular Weight:60.0408





                    Section 10 - Stability and Reactivity



Chemical Stability: Stable under normal temperatures and pressures.

Conditions to Avoid: Incompatible materials, dust generation, excess heat.

Incompatibilities with Other Materials: Strong oxidizing agents, sodium hypochlorite,

sodium nitrate, calcium hypochlorite, nitrosyl perchlorate, gallium perchlorate,

diphosphorus pentachloride.

Hazardous Decomposition Products: Carbon monoxide, oxides of nitrogen, irritating

and toxic fumes and gases, carbon dioxide.

Hazardous Polymerization: Has not been reported.





                  Section 11 - Toxicological Information



RTECS#:

CAS# 57-13-6: YR6250000

LD50/LC50:

CAS# 57-13-6:

Oral, mouse: LD50 = 11 gm/kg;

Oral, rat: LD50 = 8471 mg/kg;

Carcinogenicity:

CAS# 57-13-6: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.

Epidemiology: Oral, rat: TDLo = 821 gm/kg/1Y-C (Tumorigenic - neoplastic b y RTECS

criteria - Blood - tumors and Blood - lymphoma, in cluding Hodgkin's disease).; Oral,

mouse: TDL0 = 394 gm/kg /1Y-C (Tumorigenic - Carcinogenic by RTECS criteri a - Blood

- tumors and Blood - lymphoma, including Hodgkin's disease).

Teratogenicity: No information available.

Reproductive Effects: Intraplacental, woman: TDLo = 1400 mg/kg (female 16 week(s)

after conception) Fertility - abortion.; Intraplacental, woman: TDLo = 1600 mg/kg

(female 16 week(s) after conception) Fertility - abortion.

Neurotoxicity: No information available.

Mutagenicity: DNA Inhibition: Human, Lymphocyte = 600 mmol/L.; Cytogenetic

Analysis: Human, Leukocyte = 50 mmol/L.; DNA Damage: Mouse, Lymphocyte = 628

mmol/L.; Mutation in Mammalian Somatic Cells: Mouse, Lymphocyte = 265 mmol/L.

Other Studies: Standard Draize test: Administration onto the skin (human) = 22 mg/3D

(Intermittent) (Mild).





                      Section 12 - Ecological Information



Ecotoxicity: Bacteria: Phytobacterium phosphoreum: EC50 = 23914 mg/L; 5 min;

Microtox test If released to water, urea can degrade readily through biotic hydrolysis as

demonstrated by various screening studies. The presence of naturally-occurring

phytoplankton increases the degradation rate because phytoplankton use urea as a

nitrogen source and because urea is decomposed by phytoplankton photosynthesis. In

phytoplankton-rich waters, degradation occurs much faster in sunlight than in the dark.

Abiotic hydrolysis of urea occurs very slowly in relation to biotic hydrolysis.

Environmental: If released to the atmosphere, urea will degrade rapidly in the vapor-

phase by reaction with photochemically produced hydroxyl radicals (half-life of 9.6 hr). If

released to soil, urea is hydrolyzed to ammonium through soil urease activity (the basis

of its use as a fertilizer). The rate of hydrolysis can be fast (24 hr); however, a number a

variables (such as increasing the pellet size of the fertilizer) can decrease the degradation

rate from days to weeks.

Physical: No information found.

Other: No information found.





                     Section 13 - Disposal Considerations



Chemical waste generators must determine whether a discarded chemical is classified as

a hazardous waste. US EPA guidelines for the classification determination are listed in 40

CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous

waste regulations to ensure complete and accurate classification.

RCRA P-Series: None listed.

RCRA U-Series: None listed.





                      Section 14 - Transport Information



                   US DOT        IATA         RID/ADR            IMO           Canada TDG

                 No

   Shipping                                                              No information

                 information

    Name:                                                                  available.

                 available.

 Hazard Class:

  UN Number:

Packing Group:







                      Section 15 - Regulatory Information



US FEDERAL



TSCA

CAS# 57-13-6 is listed on the TSCA inventory.

Health & Safety Reporting List

None of the chemicals are on the Health & Safety Reporting List.

Chemical Test Rules

None of the chemicals in this product are under a Chemical Test Rule.

Section 12b

None of the chemicals are listed under TSCA Section 12b.

TSCA Significant New Use Rule

None of the chemicals in this material have a SNUR under TSCA.

SARA



CERCLA Hazardous Substances and corresponding RQs

None of the chemicals in this material have an RQ.

SARA Section 302 Extremely Hazardous Substances

None of the chemicals in this product have a TPQ.

SARA Codes

CAS # 57-13-6: acute.

Section 313

No chemicals are reportable under Section 313.

Clean Air Act:

This material does not contain any hazardous air pollutants. This material does not

contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone

depletors.

Clean Water Act:

None of the chemicals in this product are listed as Hazardous Substances under the CWA.

None of the chemicals in this product are listed as Priority Pollutants under the CWA.

None of the chemicals in this product are listed as Toxic Pollutants under the CWA.

OSHA:

None of the chemicals in this product are considered highly hazardous by OSHA.

STATE

CAS# 57-13-6 can be found on the following state right to know lists: Minnesota.

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives

Hazard Symbols:

Not available.

Risk Phrases:



Safety Phrases:



WGK (Water Danger/Protection)

CAS# 57-13-6: 1

Canada - DSL/NDSL

CAS# 57-13-6 is listed on Canada's DSL List.

Canada - WHMIS

This product has a WHMIS classification of D2A, D2B.

Canadian Ingredient Disclosure List

Exposure Limits





                          Section 16 - Additional Information



MSDS Creation Date: 5/28/1999

Revision #2 Date: 3/18/2003

The information above is believed to be accurate and represents the best information currently available to

us. However, we make no warranty of merchantability or any other warranty, express or implied, with

respect to such information, and we assume no liability resulting from its use. Users should make their own

investigations to determine the suitability of the information for their particular purposes. In no event shall

Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special,

indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been

advised of the possibility of such damages.