863 Valley View Road
Eighty Four, PA 15330 U.S.A.
Telephone: (724) 941-9701
Fax: (724) 941-1369
Toll Free: 800-752-8472
e-mail: skctech@skcinc.com
WWW: www.skcinc.com
Material Safety Data Sheet (MSDS)
Revision Date: 12 July 2005
Section 1 .... Product Identification ..................................................................................................................
Used In: 225-9023, -9023A, and -9050
Tradename: Toluene Synonyms: Methylbenzene; Toluol; Phenylmethane
CAS No.: 108-88-3 Molecular Weight: 92.14
Chemical Formula: C6H5-CH3, C7H8
Section 2 .... Composition/Information of Ingredients ....................................................................................
CAS #: Percent: Hazardous:
108-88-3 100% Yes
Section 3 .... Hazards Identification ..................................................................................................................
Emergency Overview
POISON! DANGER! HARMFUL OR FATAL IF SWALLOWED. HARMFUL IF INHALED OR ABSORBED
THROUGH SKIN. VAPOR HARMFUL. FLAMMABLE LIQUID AND VAPOR. MAY AFFECT LIVER,
KIDNEYS, BLOOD SYSTEM, OR CENTRAL NERVOUS SYSTEM. CAUSES IRRITATION TO SKIN,
EYES AND RESPIRATORY TRACT.
SAF-T-DATATM Ratings (Provided here for your convenience)
Health Rating: 2 - Moderate (Life)
Flammability Rating: 3 - Severe (Flammable)
Reactivity Rating: 1 - Slight
Contact Rating: 3 - Severe (Life)
Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD; PROPER GLOVES;
CLASS B EXTINGUISHER
Storage Color Code: Red (Flammable)
Potential Health Effects
Inhalation: Inhalation may cause irritation of the upper respiratory tract. Symptoms of overexposure
may include fatigue, confusion, headache, dizziness and drowsiness. Peculiar skin
sensations (e. g. pins and needles) or numbness may be produced. Very high concentrations
may cause unconsciousness and death.
Ingestion: Swallowing may cause abdominal spasms and other symptoms that parallel over-exposure
from inhalation. Aspiration of material into the lungs can cause chemical pneumonitis,
which may be fatal.
Skin Contact: Causes irritation. May be absorbed through skin.
Eye Contact: Causes severe eye irritation with redness and pain.
Chronic Exposure: Reports of chronic poisoning describe anemia, decreased blood cell count and bone
marrow hypoplasia. Liver and kidney damage may occur. Repeated or prolonged contact
has a defatting action, causing drying, redness, dermatitis. Exposure to toluene may affect
the developing fetus.
Aggravation of
Pre-existing Conditions: Persons with pre-existing skin disorders or impaired liver or kidney function may be more
susceptible to the effects of this substance. Alcoholic beverage consumption can enhance
the toxic effects of this substance.
Publication 1701 Rev 0507 Page 1 of 6
863 Valley View Road
Eighty Four, PA 15330 U.S.A.
Telephone: (724) 941-9701
Fax: (724) 941-1369
Toll Free: 800-752-8472
e-mail: skctech@skcinc.com
WWW: www.skcinc.com
Material Safety Data Sheet (MSDS)
Tradename: Toluene
Section 4 .... First-aid Measures ........................................................................................................................
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is
difficult, give oxygen. CALL A PHYSICIAN IMMEDIATELY.
Ingestion: Aspiration hazard. If swallowed, DO NOT INDUCE VOMITING. Give large quantities of
water. Never give anything by mouth to an unconscious person. Get medical attention
immediately. If vomiting occurs, keep head below hips to prevent aspiration into lungs.
Skin Contact: In case of contact, immediately flush skin with plenty of soap and water for at least 15
minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Call a physician immediately.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper
eyelids occasionally. Get medical attention immediately.
Section 5 .... Fire Fighting Measures ................................................................................................................
Fire:
Flash point: 7C (45F) CC
Autoignition
temperature: 422C (792F)
Flammable limits
in air % by volume: lel: 3.3; uel: 19
Flammable liquid and vapor!
Dangerous fire hazard when exposed to heat or flame. Vapors can flow along
surfaces to distant ignition source and flash back.
Explosion: Above flash point, vapor-air mixtures are explosive within flammable limits noted above.
Contact with strong oxidizers may cause fire or explosion. Sensitive to static discharge.
Fire Extinguishing Media:
Dry chemical, foam or carbon dioxide. Water may be used to flush spills away from exposures and to dilute spills to
non-flammable mixtures.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full
facepiece operated in the pressure demand or other positive pressure mode. Water spray may be used to keep fire
exposed containers cool.
Section 6 .... Accidental Release Measures .....................................................................................................
Ventilate area of leak or spill. Remove all sources of ignition. Wear appropriate personal protective equipment as
specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected personnel from entering. Contain and
recover liquid when possible. Use non-sparking tools and equipment. Collect liquid in an appropriate container or
absorb with an inert material (e. g., vermiculite, dry sand, earth), and place in a chemical waste container. Do not use
combustible materials, such as saw dust. Do not flush to sewer! If a leak or spill has not ignited, use water spray to
disperse the vapors, to protect personnel attempting to stop leak, and to flush spills away from exposures. US
Regulations (CERCLA) require reporting spills and releases to soil, water and air in excess of reportable quantities.
The toll free number for the US Coast Guard National Response Center is (800) 424-8802.
J. T. Baker SOLUSORB?solvent adsorbent is recommended for spills of this product.
Section 7 .... Handling and Storage ..................................................................................................................
Protect against physical damage. Store in a cool, dry well-ventilated location, away from any area where the fire
hazard may be acute. Outside or detached storage is preferred. Separate from incompatibles. Containers should be
bonded and grounded for transfers to avoid static sparks. Storage and use areas should be No Smoking areas. Use
non-sparking type tools and equipment, including explosion proof ventilation. Containers of this material may be
hazardous when empty since they retain product residues (vapors, liquid); observe all warnings and precautions listed
for the product.
Publication 1701 Rev 0507 Page 2 of 6
863 Valley View Road
Eighty Four, PA 15330 U.S.A.
Telephone: (724) 941-9701
Fax: (724) 941-1369
Toll Free: 800-752-8472
e-mail: skctech@skcinc.com
WWW: www.skcinc.com
Material Safety Data Sheet (MSDS)
Tradename: Toluene
Section 8 .... Exposure Controls/Personal Protection ....................................................................................
Airborne Exposure Limits:
Toluene:
- OSHA Permissible Exposure Limit (PEL):
200 ppm (TWA); 300 ppm (acceptable ceiling conc.); 500 ppm (maximum conc.).
- ACGIH Threshold Limit Value (TLV):
50 ppm (TWA) skin, A4 - Not Classifiable as a Human Carcinogen.
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne
Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the
contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH
document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded and engineering controls are not feasible, a half-face organic vapor respirator may
be worn for up to ten times the exposure limit, or the maximum use concentration specified by the appropriate
regulatory agency or respirator supplier, whichever is lowest. A full-face piece organic vapor respirator may be
worn up to 50 times the exposure limit, or the maximum use concentration specified by the appropriate regulatory
agency or respirator supplier, whichever is lowest. For emergencies or instances where the exposure levels are not
known, use a full-face piece positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not
protect workers in oxygen-deficient atmospheres.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to
prevent skin contact.
Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and
quick-drench facilities in work area.
Section 9 .... Physical and Chemical Properties ..............................................................................................
Appearance: Clear, colorless liquid. Melting Point: -95C (-139F)
Odor: Aromatic benzene-like. Vapor Density
Solubility: 0.05 gm/100gm water @ 20C (68F). (Air=1): 3.14
Specific Gravity: 0.86 @ 20C / 4 C Vapor Pressure
pH: No information found. (mm Hg): 22 @ 20C (68F)
% Volatiles by vol. Evaporation
@ 21C (70F): 100 Rate (BuAc=1): 2.24
Boiling Point: 111C (232F)
Section 10 .. Stability and Reactivity ................................................................................................................
Stability: Stable under ordinary conditions of use and storage. Containers may burst when heated.
Hazardous Decomposition Products:
Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous
Polymerization: Will not occur.
Incompatibilities: Heat, flame, strong oxidizers, nitric and sulfuric acids, chlorine, nitrogen tetraoxide; will
attack some forms of plastics, rubber, coatings.
Conditions to Avoid: Heat, flames, ignition sources and incompatibles.
Publication 1701 Rev 0507 Page 3 of 6
863 Valley View Road
Eighty Four, PA 15330 U.S.A.
Telephone: (724) 941-9701
Fax: (724) 941-1369
Toll Free: 800-752-8472
e-mail: skctech@skcinc.com
WWW: www.skcinc.com
Material Safety Data Sheet (MSDS)
Tradename: Toluene
Section 11 .. Toxicological Information ............................................................................................................
Toxicological Data:
Oral rat LD50: 636 mg/kg; skin rabbit LD50: 14100 uL/kg; inhalation rat LC50: 49 gm/m3/4H; Irritation data: skin
rabbit, 500 mg, Moderate; eye rabbit, 2 mg/24H, Severe. Investigated as a tumorigen, mutagen, reproductive effector.
Reproductive Toxicity:
Has shown some evidence of reproductive effects in laboratory animals.
Cancer Lists
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Toluene (108-88-3) No No 3
Section 12 .. Ecological Considerations ..........................................................................................................
Environmental Fate: When released into the soil, this material may evaporate to a moderate extent. When
released into the soil, this material is expected to leach into groundwater. When released
into the soil, this material may biodegrade to a moderate extent. When released into water,
this material may evaporate to a moderate extent. When released into water, this material
may biodegrade to a moderate extent. When released into the air, this material may be
moderately degraded by reaction with photochemically produced hydroxyl radicals. When
released into the air, this material is expected to have a half-life of less than 1 day. This
material is not expected to significantly bioaccumulate. This material has a log octanol-
water partition coefficient of less than 3.0. Bioconcentration factor = 13.2 (eels).
Environmental Toxicity: This material is expected to be toxic to aquatic life. The LC50/96-hour values for fish are
between 10 and 100 mg/l.
Section 13 .. Disposal Considerations .............................................................................................................
Whatever cannot be saved for recovery or recycling should be handled as hazardous waste and sent to a RCRA
approved incinerator or disposed in a RCRA approved waste facility. Processing, use or contamination of this
product may change the waste management options. State and local disposal regulations may differ from federal
disposal regulations. Dispose of container and unused contents in accordance with federal, state and local require-
ments.
Section 14 .. Transport Information ..................................................................................................................
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: TOLUENE
Hazard Class: 3
UN/NA: UN1294
Packing Group: II
Information reported
for product/size: 390LB
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: TOLUENE
Hazard Class: 3
UN/NA: UN1294
Packing Group: II
Information reported
for product/size: 390LB
Publication 1701 Rev 0507 Page 4 of 6
863 Valley View Road
Eighty Four, PA 15330 U.S.A.
Telephone: (724) 941-9701
Fax: (724) 941-1369
Toll Free: 800-752-8472
e-mail: skctech@skcinc.com
WWW: www.skcinc.com
Material Safety Data Sheet (MSDS)
Tradename: Toluene
Section 15 .. Regulatory Information ................................................................................................................
Chemical Inventory Status - Part 1
Ingredient TSCA EC Japan Australia
----------------------------------------------- -------- ---- -------- ------------
Toluene (108-88-3) Yes Yes Yes Yes
Chemical Inventory Status - Part 2
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- -------- ----- -------- ------
Toluene (108-88-3) Yes Yes No Yes
Federal, State & International Regulations - Part 1
--SARA 302-- ---------SARA 313---------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------------- ---- ------ ----- --------------------
Toluene (108-88-3) No No Yes No
Federal, State & International Regulations - Part 2
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------------- ------------ -------- -----
Toluene (108-88-3) 1000 U220 No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: Yes
SARA 311/312: Acute: Yes Chronic: Yes Fire: Yes Pressure: No
Reactivity: No (Pure / Liquid)
WARNING:
THIS PRODUCT CONTAINS A CHEMICAL(S) KNOWN TO THE STATE OF CALIFORNIA TO CAUSE
BIRTH DEFECTS OR OTHER REPRODUCTIVE HARM.
Australian Hazchem Code: 3[Y]E
Poison Schedule: S6
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the
MSDS contains all of the information required by the CPR.
Publication 1701 Rev 0507 Page 5 of 6
863 Valley View Road
Eighty Four, PA 15330 U.S.A.
Telephone: (724) 941-9701
Fax: (724) 941-1369
Toll Free: 800-752-8472
e-mail: skctech@skcinc.com
WWW: www.skcinc.com
Material Safety Data Sheet (MSDS)
Tradename: Toluene
Section 16 .. Other Information .........................................................................................................................
NFPA Ratings: Health: 2 Flammability: 3 Reactivity: 0
Label Hazard Warning:
POISON! DANGER! HARMFUL OR FATAL IF SWALLOWED. HARMFUL IF INHALED OR
ABSORBED THROUGH SKIN. VAPOR HARMFUL. FLAMMABLE LIQUID AND VAPOR. MAY
AFFECT LIVER, KIDNEYS, BLOOD SYSTEM, OR CENTRAL NERVOUS SYSTEM. CAUSES
IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT.
Label Precautions:
? Keep away from heat, sparks and flame.
? Keep container closed.
? Use only with adequate ventilation.
? Wash thoroughly after handling.
? Avoid breathing vapor.
? Avoid contact with eyes, skin and clothing.
Label First Aid:
? Aspiration hazard. If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water. Never give
anything by mouth to an unconscious person. If vomiting occurs, keep head below hips to prevent aspiration
into lungs.
? If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
? In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes. Remove
contaminated clothing and shoes.
? Wash clothing before reuse.
? In all cases call a physician immediately.
Product Use:
Laboratory Reagent.
Revision Information:
MSDS Section(s) changed since last revision of document include: 3.
Disclaimer:
**********************************************************************************************************************************************************************************
Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This
document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals
receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT BAKER,
INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES
OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT
TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULT-
ING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
***********************************************************************************************************************************************************************************
Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)
Publication 1701 Rev 0507 Page 6 of 6
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