TOKU-E COMPANY
MATERIAL SAFETY DATA SHEET
EMERGENCY PHONE (USA only): +1-800-535-5053 INF.: +86-21-5206 9530
. Substance identification
Nalidixic Acid
. Composition/ information on ingredients
CAS No.: 389-08-2
FW: C12H12N2O
. Hazard identification
Label precautionary statements
Harmful.
May cause sensitization by inhalation and skin contact.
Possible Carcinogen (US). Photosensitizer.
Target organ(s): Blood. Central nervous system.
In case of accident or if you feel unwell, seek medical advice immediately (show
label when possible). Wear suitable protective clothing, gloves and eye/ face
protection.
. First-aid measures
In case of contact, immediately flush eyes or skin with copious amounts of water
at least 15minutes while removing contaminated clothing and shoes. Assure
adequate flushing of eyes by separating eyelids with fingers. If inhaled, remove
to fresh air. If breathing is difficult, call a physician. If swallowed, wash out mouth
with water (provided person is conscious). Call a physician immediately. Wash
all contaminated clothing before reuse.
. Fire extinguishing measures.
Extinguishing media: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
Wear self-contained breathing apparatus and protective clothing to prevent
contact with eyes and skin.
Unusual fire and explosion hazards:
Emits toxic fumes under fire conditions.
. Accidental release measures
Evacuate area. Wear respirator, chemical safety goggles, rubber boots, and
heavy rubber gloves.
Sweep up; avoid raising dust, place in a bag and hold for waste disposal.
Ventilate area and wash spill site after material pickup is complete.
MSDS Nalidixic Acid 1/4
. Handling and storage
Wear Government approved respirator in nonventilated areas and/ or for
exposure above the TLV or PEL, chemical resistant gloves, safety goggles, and
all other protective clothing. Do not breathe dust. Avoid prolonged or repeated
exposure. Do not get in eyes, on skin, on clothing. Safety shower and eye bath.
Wash contaminated clothing before reuse. Wash thoroughly after handling. Use
only in a chemical fume hood.
Keep tightly closed. Store in a dry cool place.
. Physical properties
Appearance: Solid
PH: N/A
Melting point: 228癈
Solubility: 20 MG/ML CHCl3 Clear
. Stability and reactivity
Stable. Avoid strong oxidizing agents.
Hazardous combustion or decomposition products thermal decomposition may
produce carbon monoxide, carbon dioxide, nitrogen oxides.
Hazardous polymerization will not occur.
. Toxicological information
May cause skin irritation. May be harmful if absorbed through the skin.
May cause eye irritation. May be harmful if inhaled. Material may be irritating to
mucous membranes and upper respiratory tract. Harmful if swallowed.
Sensitization: Causes photosensitivity. Exposure to light can result in allergic
reactions resulting in dermatologic lesions, which can vary from sunburnlike
responses to edematous, vesiculated lesions, or bullae. May cause allergic
respiratory reaction. May cause allergic skin reaction.
Signs and symptoms of exposure: May cause hyperglycemia, exacerbation of
epilepsy, and photosensitive reactions of the skin and eyes. Possible skin
reactions may include hyperpigmentation, swelling, redness, and blistering.
Possible eye changes may include keratoconjunctivitis or corneal and lens
opacities. Exposure can cause: Nausea, dizziness, and headache. Stomach
pains, vomiting, diarrhea. Drowsiness. Confusion. Weakness.
Target organ(s): Blood. Central nervous system. Eyes.
Toxicity data:
Oral Rat LD50: 2040 MG/KG
Intraperitoneal Rat LD50: 319MG/KG
Subcutaneous Rat LD50: 1584 MG/KG
Intravenous Rat LD50: 1160 MG/KG
Oral Mouse LD50: 572 MG/KG
Intraperitoneal Mouse LD50: 600 MG/KG
Subcutaneous Mouse LD50: 500 MG/KG
Intrvenous Mouse LD50: 101 MG/KG
MSDS Nalidixic Acid 2/4
Chronic exposure: Carcinogen. This product is or contains a component that has
been reported to be possibly carcinogenic based on its IARC, ACGIH, NTP, or
EPA classification.
Teratogen. Mutagen. Reproductive hazards.
NTP carcinogen list: Rating: Clear evidence.
Species: Rat
Route: Feed
Only selected registry of toxic effects of chemical substances (RTECS) data is
presented here. See actual entry in trees for complete information.
.Ecological information: No data available.
. Disposal considerations
Contact a licensed professional waste disposal service to dispose of this material.
Dissolve or mix the material with a combustible solvent and burn in a chemical
incinerator equipped with an afterburner and scrubber. Observe all federal, state
and local environmental regulations.
. Transport information:
This substance is considered to be non-hazardous for transport.
Non-hazardous for air transport.
. Regulatory information
US information
Harmful.
May cause sensitization by inhalation and skin contact.
Do not breathe dust. Wear suitable protective clothing and gloves. In case of
accident or if you feel unwell, seek medical advice immediately (show the label
where possible).
Possible Carcinogen (US). Photosensitizer.
Target organ(s): Blood. Central nervous system.
SARA list: No.
EU information:
Harmful.
R: 42/43
May cause sensitization by inhalation and skin contact.
S: 22 36/37 45
Do not breathe dust. Wear suitable protective clothing and gloves. In case of
accident or if you feel unwell, seek medical advice immediately (show the label
where possible).
Canada information
This product has been classified in accordance with the hazard criteria of the
CPR, and the MSDS contains all the information required by the CPR.
DSL: No.
NDSL: No
MSDS Nalidixic Acid 3/4
. Other Information
The information and recommendations set forth herein are believed to be
completed and faithful. However, it is the user's responsibility to determine the
suitability for his/ her purpose prior to use. Toku-E Company assumes no
additional liability and responsibility resulting from use and/ or reliance on this
information.
MSDS Nalidixic Acid 4/4
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