Material Safety Data Sheet
Section 1 - Product and Company Information
Triptolide
Product Name:
ant-tpl
Cat. Code:
InvivoGen, 3950 Sorrento Valley Blvd, Suite 100
San Diego, California 92121, USA
(+1) 858 457 5873
Company identification:
Cayla-InvivoGen, 5 rue Jean Rodier
31400 Toulouse, FRANCE
+33 (0) 5 62 71 69 39
Section 2 - Composition/Information on Ingredient
Synonym: PG 490 Molecular Weight: 360.4
Formula: C20H24O6 CAS #: 38748-32-2
EC #: N/A
Section 3 ?Hazards Identification
OSHA Hazards: No known OSHA hazards.
HMIS Classification: Health Hazard 0, Flammability Hazard 0, Reactivity Hazard 0
NFPA Rating: Health Hazard 0, Fire 0, Reactivity Hazard 0
Potential Health Effects
- Eye contact: May cause eye irritation.
- Skin contact: May cause skin irritation.
- Skin absorption: May be harmful if absorbed through the skin.
- Inhalation: May be harmful if inhaled. May cause respiratory tract irritation.
- Ingestion: May be harmful if swallowed.
Section 4 ?First Aid Measures
General advice: Consult a physician. Show this material safety data sheet to the doctor in attendance.
After skin contact: Immediately wash skin with soap and plenty of water. Consult a physician.
After swallowing: Never give anything by mouth to an unconscious person. Rinse mouth with water provided person is
conscious. Consult a physician.
After inhalation: Remove to fresh air. If not breathing give artificial respiration. Consult a physician.
After eye contact: Immediately flush eyes with plenty of water for at least 15 minutes. Consult a physician.
Section 5 ?Fire Fighting Measures
Extinguishing Media: Water spray, carbon dioxide, dry chemical powder or appropriate foam.
Special Firefighting Procedures: Wear self-contained breathing apparatus and protective clothing to prevent contact with
skin and eyes.
Unusual Fire and Explosions Hazard (s): N/A Flash point: N/A
Auto-ignition Temp: N/A Flammability: N/A
3950 Sorrento Valley Blvd, Suite 100, San Diego, CA 92121, USA Revision Date 07/09/09
Phone US: (858) 457 5873 - Fax US: (858) 457 5843
Phone EU: +33 (0) 5 62 71 69 39 - Fax EU: +33 (0) 5 62 71 69 30
Website : www.invivogen.com
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Email : info@invivogen.com
Material Safety Data Sheet
Section 6 ?Accidental Release Measures
Personal precautions: Wear protective equipment. Keep unprotected persons away. Avoid dust formation.
Method for cleaning up: Absorb on sand or vermiculite and place in closed containers for disposal. Dispose contaminated
material as waste according to section 13. Ventilate area and wash spill site after material clean-up is complete.
Section 7?Handling and Storage
Handling: Avoid contact with eyes, skin and clothing. Avoid prolonged or repeated exposure.
User Exposure: Avoid inhalation. Use personal protective equipment (i.e. impermeable gloves, lab coat or apron).
Storage: Keep tightly closed. Store at -20癈.
Section 8 ?Exposure Controls / PPE
Engineering Measures: Ensure adequate ventilation, especially in confined areas.
Personal Protective Equipment
Hand: Protective gloves to prevent skin contact. Eye: Chemical safety goggles
General Hygiene Measures: Wash hands thoroughly after handling.
Section 9 ?Physical / Chemical Properties
Appearance: White
Physical State: Solid
Section 10 ?Stability and Reactivity
Stability: Stable
Hazardous Polymerization: Will not occur
Materials to avoid: Strong oxidizing agents
Hazardous Decomposition Products: Hazardous decomposition products formed under fire conditions. Carbon oxides.
Section 11 ?Toxicological Information
Acute toxicity:
LD50 Oral: N/A
LD50 Intraperitoneal: 0.9 mg/kg mouse
LD50 Intravenous: 0.8 mg/kg mouse
LD50 subcutaneous: N/A
Primary irritant effect: N/A
Sensitization: N/A
Additional toxicological information: RTECS:YK7751000
Section 12 ?Ecological Information
Ecotoxicity: Data not yet available. Biodegradation: Data not yet available.
Mobility: Data not yet available. Bioaccumulation: Data not yet available.
3950 Sorrento Valley Blvd, Suite 100, San Diego, CA 92121, USA Revision Date 07/09/09
Phone US: (858) 457 5873 - Fax US: (858) 457 5843
Phone EU: +33 (0) 5 62 71 69 39 - Fax EU: +33 (0) 5 62 71 69 30
Website : www.invivogen.com
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Email : info@invivogen.com
Material Safety Data Sheet
Section 13 ?Disposal Considerations
Product: Observe all federal, state and local environmental regulations. Contact a licensed professional waste disposal service
to dispose of this material. Must not be disposed of together with household garbage.
Contaminated Packaging: Dispose of as unused product.
Section 14 ?Transport Information
DOT (US): Not dangerous goods.
IATA: Not dangerous goods.
IMDG: Not dangerous goods.
Section 15 ?Regulatory Information
OSHA HAZARDS (US): No known OSHA hazards.
DSL Status: This product contains the following components that are on the Canadian NDSL list. This product contains the
following components that are not on the Canadian DSL list.
Triptolide CAS #: 38748-32-2
SARA 302 Component: None of the ingredients are listed.
SARA 313 Component: None of the ingredients are listed.
SARA 311/312 Hazards: None of the ingredients are listed.
U.S. State Regulations
Chemical Name Massachusetts RTK New Jersey RTK Pennsylvania RTK
Triptolide - X X
California Proposition 65: This product does not contain chemicals listed under Proposition 65.
Labeling and risk phrase according to EU Directives: The product does not need to be labeled in accordance with EC
directives or respective national laws.
Section 16 ?Other Information
Disclaimer: All InvivoGen products are supplied for research and laboratory use only. Not for drug, household or other uses.
The information contained in this MSDS relates only to the material(s) designated and does not relate to use(s) in combination
with any other material, process(es) and/or chemical reaction(s). InvivoGen provides this information in good faith and is
based on our present knowledge. This MSDS is provided without warranty of any kind. The recipient is responsible for
ensuring that, where applicable, existing laws and guidelines are observed.
3950 Sorrento Valley Blvd, Suite 100, San Diego, CA 92121, USA Revision Date 07/09/09
Phone US: (858) 457 5873 - Fax US: (858) 457 5843
Phone EU: +33 (0) 5 62 71 69 39 - Fax EU: +33 (0) 5 62 71 69 30
Website : www.invivogen.com
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Email : info@invivogen.com
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