SAFETY DATA SHEET
XENOMETRIX
by Endotell
GLU Kit (Cellular Metabolism
and Glucose Consumption)
Version 1.1 Page 1/3 Processing date 14.12.2007
1. IDENTIFICATION OF THE TEST KIT AND THE COMPANY
Product information
Product Name: IN CYTOTOX Glucose Kit
Cat.-No.: AKGLU 96.400, AKGLU 96.1200
and as part of: AKLGXP 96.300, AKLGXP 96.1200
AKLGXS 96.300, AKLGXS 96.1200
plus all above with plasticware (x96.3/410, x96.1210)
Intended use: Research use only, not for diagnostic purposes
Company: Xenometrix by Endotell GmbH
Gewerbestrasse 25
CH-4123 Allschwil
Telephone: +41 61 482 14 34
Telefax: +41 61 482 20 72
1
2. CHEMICAL CHARACTERISATION
Kit contents (chemicals)
GLU I:
Contains no hazardous substances in concentrations to be declared
GLU II:
Labelling: Orthodianisidine; CAS-No. 20325-40-0
3. HAZARDS IDENTIFICATION
Risk advice to man and the environment
GLU I: Inhalation of dust may cause allergic reaction or sensitisation.
GLU II: Harmful if swallowed, inhaled or absorbed through skin. Causes eye and skin irritation.
Material is irritating to mucous membranes and upper respiratory tract. Causes sneezing. Do not
inhale. Chronic effects: Carcinogen. May alter genetic material. Target organ: Bladder.
The usual precautions taken when handling chemicals should be observed.
4. FIRST AID MEASURES
GLU I and GLU II:
Skin contact: Wash skin with water thoroughly.
Eye contact: Promptly wash eyes with water for at least 15 minutes, if necessary
seek medical advice.
Ingestion: Obtain medical attention.
Instructions for physician: Symptomatic treatment by a physician.
6560 Gove Court Phone: 513-770-1991 Toll Free: 866-783-3797 FAX: 513-573-9241
Aniara Mason, OH 45040 Web: www.aniara.com Email: info@aniara.com
SAFETY DATA SHEET
XENOMETRIX
by Endotell
GLU Kit (Cellular Metabolism
and Glucose Consumption)
Version 1.1 Page 2/3 Processing date 14.12.2007
5. FIRE-FIGHTING MEASURES
Extinguishing media: No restriction.
Decomposition: GLU II: Emits toxic fumes under fire conditions.
6. ACCIDENTAL RELEASE MEASURES
GLU I:
Actions to be taken on spillage: Smaller quantities can be washed off with plenty of water.
Absorbent material: No restriction.
Actions to be taken to limit damage: Special measures to limit damage are not necessary.
GLU II:
Actions to be taken on spillage: Avoid skin contact. Dispose with laboratory waste. Wash spill
area.
Absorbent material: No restriction.
Actions to be taken to limit damage: Special measures to limit damage are not necessary.
7. HANDLING AND STORAGE
Handling: No special requirements.
Storage: Store whole kit at temperature of about -20癈.
Do not store together with: No restriction.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Personal protective equipment
Respiratory protection: No personal respiratory protective equipment normally required.
Eye protection: Safety glasses
Hand protection: Protective gloves
Hygiene measures: Wash hands before breaks and at the end of workday.?br>
6560 Gove Court Phone: 513-770-1991 Toll Free: 866-783-3797 FAX: 513-573-9241
Aniara Mason, OH 45040 Web: www.aniara.com Email: info@aniara.com
SAFETY DATA SHEET
XENOMETRIX
by Endotell
GLU Kit (Cellular Metabolism
and Glucose Consumption)
Version 1.1 Page 3/3 Processing date 14.12.2007
9. PHYSICAL AND CHEMICAL PROPERTIES
GLU I and GLU II:
Form: solid
Miscibility with water: completely miscible
10. STABILITY AND REACTIVITY
GLU I:
Hazardous reactions: none under normal use
Hazardous decomposition products: none under normal use
GLU II:
Hazardous reactions: none under normal use
Hazardous decomposition products: only in small concentrations (Carbon monoxide, nitrogen
oxides, HCl gas)
11. TOXICOLOGICAL INFORMATION
GLU II: Tumorigenic
12. ECOLOGICAL INFORMATION
Water hazard class: No information available
13. DISPOSAL CONSIDERATIONS
Waste disposal route: Small quantities may be disposed off in waste water.
Disposal of empty packaging: Dispose of empty packs via laboratory waste disposal routes.
14. TRANSPORT INFORMATION
Is not subject to current regulations for transportation of dangerous goods (ADR/RID, IMDG,
IATA/ICAO)
6560 Gove Court Phone: 513-770-1991 Toll Free: 866-783-3797 FAX: 513-573-9241
Aniara Mason, OH 45040 Web: www.aniara.com Email: info@aniara.com
SAFETY DATA SHEET
XENOMETRIX
by Endotell
XTT Kit (Tetrazolium Hydroxide;
Mitochondrial Metabolism)
Version 1.1 Page 1/3 Processing date 14.12.2007
1. IDENTIFICATION OF THE TEST KIT AND THE COMPANY
Product information
Product Name: XTT Kit
Cat.-No.: AKXT 96.300, AKXT 96.1200
and as part of: AKXCV 96.300, AKXCV 96.1200
AKLEX 96.300, AKLEX 96.1200
AKXPAC 96.300, AKXPAC 96.1200
AKXSR 96.300, AKXSR 96.1200
AKLEXR 96.300, AKLEXR 96.1200
AKLEXSR 96.300, AKLEXSR 96.1200
AKXTSCV 96.300, AKXTSCV 96.1200
AKXTRS 96.300, AKXTRS 96.1200
AKLGXP 96.300, AKLGXP 96.1200
AKLGXS 96.300, AKLGXS 96.1200
APAN I 96.300, APAN I 96.1200
plus all above with plasticware (x96.310, x96.1210)
Intended use: Research use only, not for diagnostic purposes
Company: Xenometrix by Endotell GmbH
Gewerbestrasse 25
CH-4123 Allschwil
Telephone: +41 61 482 14 34
Telefax: +41 61 482 20 72
1
2. CHEMICAL CHARACTERISATION
Components
XTT I:
Contains no hazardous substances in concentrations to be declared
XTT II:
Contains no hazardous substances in concentrations to be declared
3. HAZARDS IDENTIFICATION
Risk advice to man and the environment
There is at present no information or indication of hazardous properties.
The usual precautions taken when handling chemicals should be observed.
4. FIRST AID MEASURES
Skin contact: Wash skin with water thoroughly.
Eye contact: Promptly wash eyes with water for at least 15 minutes, if necessary
seek medical advice.
Ingestion: Obtain medical attention.
Instructions for physician: Symptomatic treatment by a physician.
6560 Gove Court Phone: 513-770-1991 Toll Free: 866-783-3797 FAX: 513-573-9241
Aniara Mason, OH 45040 Web: www.aniara.com Email: info@aniara.com
SAFETY DATA SHEET
XENOMETRIX
by Endotell
XTT Kit (Tetrazolium Hydroxide;
Mitochondrial Metabolism)
Version 1.1 Page 2/3 Processing date 14.12.2007
5. FIRE-FIGHTING MEASURES
Extinguishing media: No restriction.
Decomposition: Dangerous decomposition is not anticipated.
6. ACCIDENTAL RELEASE MEASURES
Actions to be taken on spillage: Smaller quantities can be washed off with plenty of water.
Absorbent material: No restriction.
Actions to be taken to limit damage: Special measures to limit damage are not necessary.
7. HANDLING AND STORAGE
Handling: The product itself does not burn. No special requirements.
Storage: Store at temperature of about -20癈 and protected from light
Do not store together with: No restriction.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Personal protective equipment
Respiratory protection: No personal respiratory protective equipment normally required.
Eye protection: Safety glasses
Hand protection: Protective gloves
Hygiene measures: Wash hands before breaks and at the end of workday.?br>
9. PHYSICAL AND CHEMICAL PROPERTIES
XTT I:
Form: liquid
Miscibility with water: completely miscible
XTT II:
Form: liquid
Miscibility with water: completely miscible
10. STABILITY AND REACTIVITY
Hazardous reactions: none under normal use
Hazardous decomposition products: only in small concentrations
6560 Gove Court Phone: 513-770-1991 Toll Free: 866-783-3797 FAX: 513-573-9241
Aniara Mason, OH 45040 Web: www.aniara.com Email: info@aniara.com
SAFETY DATA SHEET
XENOMETRIX
by Endotell
XTT Kit (Tetrazolium Hydroxide;
Mitochondrial Metabolism)
Version 1.1 Page 3/3 Processing date 14.12.2007
11. TOXICOLOGICAL INFORMATION
Toxicological information for the product
N/A
12. ECOLOGICAL INFORMATION
No information available
13. DISPOSAL CONSIDERATIONS
Waste disposal route: Small quantities may be disposed off in waste water.
Disposal of empty packaging: Dispose of empty packs via local recycling or waste disposal routes- if
necessary, clean them beforehand.
14. TRANSPORT INFORMATION
Is not subject to current regulations for transportation of dangerous goods (ADR/RID, IMDG,
IATA/ICAO)
6560 Gove Court Phone: 513-770-1991 Toll Free: 866-783-3797 FAX: 513-573-9241
Aniara Mason, OH 45040 Web: www.aniara.com Email: info@aniara.com
SAFETY DATA SHEET
XENOMETRIX
by Endotell
CVDE Kit (Crystal Violet Dye Elution;
Nuclear Protein Synthesis Rate and Cell proliferation)
Version 1.1 Page 1/4 Processing date 14.12.2007
1. IDENTIFICATION OF THE TEST KIT AND THE COMPANY
Product information
Product Name: IN CYTOTOX CVDE Kit
Cat.-No.: AKCV 96.300, AKCV 96.1200
and as part of: AKRVC 96.300, AKRCV 96.1200
AKSRCV 96.300, AKSRCV 96.1200
AKXCV 96.300, AKXCV 96.1200
AKXTSCV 96.300, AKXTSCV 96.1200
plus all above with plasticware (x96.310, x96.1210)
Intended use: Research use only, not for diagnostic purposes
Company: Xenometrix by Endotell GmbH
Gewerbestrasse 25
CH-4123 Allschwil
Telephone: +41 61 482 14 34
Telefax: +41 61 482 20 72
2. CHEMICAL CHARACTERISATION
Components:
CVDE I:
Contains no hazardous substances in concentrations to be declared
CVDE II:
Ingredient: crystal violet; CAS-No. 548-62-9
CVDE III:
Ingredients: Acetic acid 33%; CAS-No. 64-19-7
3. HAZARDS IDENTIFICATION
CVDE II:
Harmful if swallowed. May cause irritation. Avoid breathing vapors, or dusts. Use with adequate
ventilation. Avoid contact with eyes, skin, and clothes. Wash thoroughly after handling. Keep container
closed.
CVDE III:
POISON! DANGER! CORROSIVE. LIQUID AND MIST CAUSE SEVERE BURNS TO ALL BODY
TISSUE. MAY BE FATAL IF SWALLOWED. HARMFUL IF INHALED. INHALATION MAY CAUSE
LUNG AND TOOTH DAMAGE. FLAMMABLE LIQUID AND VAPOR.
Hazard evaluation based upon pure (glacial) acetic acid. Hazards of dilute solutions may not be as severe as those of glacial
acetic acid.
Inhalation:
Inhalation of concentrated vapors may cause serious damage to the lining of the nose,
throat, and lungs. Breathing difficulties may occur. Neither odor nor degree of irritation
are adequate to indicate vapor concentration.
Ingestion:
Swallowing can cause severe injury leading to death. Symptoms include sore throat,
6560 Gove Court Phone: 513-770-1991 Toll Free: 866-783-3797 FAX: 513-573-9241
Aniara Mason, OH 45040 Web: www.aniara.com Email: info@aniara.com
SAFETY DATA SHEET
XENOMETRIX
by Endotell
CVDE Kit (Crystal Violet Dye Elution;
Nuclear Protein Synthesis Rate and Cell proliferation)
Version 1.1 Page 2/4 Processing date 14.12.2007
vomiting, and diarrhea. Ingestion of as little as 1.0 ml has resulted in perforation of the
esophagus.
Skin Contact:
Contact with concentrated solution may cause serious damage to the skin. Effects may
include redness, pain, skin burns. High vapor concentrations may cause skin
sensitization.
Eye Contact:
Eye contact with concentrated solutions may cause severe eye damage followed by loss
of sight. Exposure to vapor may cause intense watering and irritation to eyes.
Chronic Exposure:
Repeated or prolonged exposures may cause darkening of the skin, erosion of exposed
front teeth, and chronic inflammation of the nose, throat, and bronchial tubes.
Aggravation of Pre-existing Conditions:
Persons with pre-existing skin disorders or eye problems, or impaired respiratory
function may be more susceptible to the effects of the substance.
4. FIRST AID MEASURES
CVDE II:
Ingestion:: If swallowed, induce vomiting immediately after giving two glasses of water. Never give
anything by mouth to an unconscious person.
Skin Contact:: Wash exposed area with soap and water. If irritation persists, seek medical attention.
Eye Contact: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek
Medical Aid. INHALATION: Remove to fresh air. If not breathing, give artificial respiration. If breathing
is difficult, give oxygen
CVDE III:
Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call
a physician.
Ingestion:
DO NOT INDUCE VOMITING! Give large quantities of water or milk if available. Never give anything
by mouth to an unconscious person. Get medical attention immediately.
Skin Contact:
In case of contact, immediately flush skin with plenty of water for at least 15 minutes
while removing contaminated clothing and shoes. Wash clothing before reuse. Call a
physician.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and
upper eyelids occasionally. Get medical attention immediately.
6560 Gove Court Phone: 513-770-1991 Toll Free: 866-783-3797 FAX: 513-573-9241
Aniara Mason, OH 45040 Web: www.aniara.com Email: info@aniara.com
SAFETY DATA SHEET
XENOMETRIX
by Endotell
CVDE Kit (Crystal Violet Dye Elution;
Nuclear Protein Synthesis Rate and Cell proliferation)
Version 1.1 Page 3/4 Processing date 14.12.2007
5. FIRE-FIGHTING MEASURES
CVDE III:
Listed fire data is for Glacial Acetic Acid. Flammable Liquid and Vapor!
Extinguishing media: No restriction.
Decomposition: Dangerous decomposition is not anticipated.
6. ACCIDENTAL RELEASE MEASURES
CVDE II:
Absorb spill with inert material. Flush excess down drain
CVDE III:
Do not inhale vapors. Avoid substance contact. Ensure supply of fresh air in enclosed rooms.
Take up with liquid-absorbent material. Forward for disposal. Clean up affected area.
7. HANDLING AND STORAGE
Handling: Avoid skin contact with contents of CVDE II and CVDE III.
Storage: Store kit at temperature of about -20癈.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Respiratory protection: Avoid breathing vapors of CVDE III: No personal respiratory protective
equipment normally required.
Eye protection: Safety glasses
Hand protection: Protective gloves
Hygiene measures: Wash hands after handling.?br>
9. PHYSICAL AND CHEMICAL PROPERTIES
CVDE I, CVDE II, CVDE III:
Form: liquid
Miscibility with water: completely miscible
10. STABILITY AND REACTIVITY
CVDE III:
Hazardous reactions: none under normal use
Hazardous decomposition products: Carbon dioxide and carbon monoxide may form when heated
to decomposition. May also release toxic and irritating vapors.
6560 Gove Court Phone: 513-770-1991 Toll Free: 866-783-3797 FAX: 513-573-9241
Aniara Mason, OH 45040 Web: www.aniara.com Email: info@aniara.com
SAFETY DATA SHEET
XENOMETRIX
by Endotell
CVDE Kit (Crystal Violet Dye Elution;
Nuclear Protein Synthesis Rate and Cell proliferation)
Version 1.1 Page 4/4 Processing date 14.12.2007
11. TOXICOLOGICAL INFORMATION
CVDE II:
LD50: 168 g/kg (oral-rat, calculated dose for actual content of CVDE II)
Has been shown to be carcinogenic in animals
Has been shown to be teratogenic in animals
Has been show to alter genetic material in tissue culture cells
CVDE III:
LD50: 1177 mg/kg (oral-rat, calculated dose for actual content of CVDE III)
CVDE I:
No toxicological information for the product
12. ECOLOGICAL INFORMATION
CVDE I:
No hazard to environment
CVDE II:
No information available
CVDE III:
Easily biodegradable in diluted form.
13. DISPOSAL CONSIDERATIONS
Waste disposal route: CVDE I and CVDE III: Small quantities may be disposed off in waste water.
CVDE II: Dispose with laboratory/chemical waste according to local
regulations
Disposal of empty packaging: Dispose of empty packs via local recycling or waste disposal routes- if
necessary, clean them beforehand.
14. TRANSPORT INFORMATION
CVDE:III:
Proper Shipping Name: ACETIC ACID, 33% SOLUTION
Hazard Class: 8
UN/NA: UN2790
Packing Group: III
Information reported for product/size: 19L
6560 Gove Court Phone: 513-770-1991 Toll Free: 866-783-3797 FAX: 513-573-9241
Aniara Mason, OH 45040 Web: www.aniara.com Email: info@aniara.com
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