Page 1 of 5
Product Information (203) 740-3471 / Emergency Assistance CHEMTREC 1-800-424-9300
or 202-483-7616
MATERIAL SAFETY DATA SHEETS
Part Number/Trade Name: Cyclohexanone
This MSDS is valid for all grades that start with catalog number 314
===========================================================================
General Information
===========================================================================
Company's Name: PHARMCO PRODUCTS, INC. Safety Data Review Date: 4/5/00
Company's Street: 58 VALE RD. Preparer's Company: PHARMCO PRODUCTS,
Company's City: BROOKFIELD INC.
Company's State: CT Preparer's St Or P. O. Box: 58 VALE RD.
Company's Zip Code: 06804 Preparer's City: BROOKFIELD
Company's Emerg Ph #: (203) 740-3471 Preparer's State: CT
Company's Info Ph #: (203) 740-3471 Preparer's Zip Code: 06804
Date MSDS Revised: 4/5/00
===========================================================================
Ingredients/Identity Information
===========================================================================
Ingredient: Cyclohexanone NIOSH (RTECS) Number: GW1050000
Synonyms: Pimelic ketone; Cyclohexyl ketone; CAS Number: 108-94-1
Ketohexamethylene Molecular weight: 98.14
Sequence Number: 01 Chemical Formula: C6H10O
Percent: 99-100% OSHA PEL: S, 50 ppm
Hazardous: Yes ACGIH TLV: S, 25 ppm; 9293
===========================================================================
Physical/Chemical Characteristics
===========================================================================
Appearance: Clear, colorless to slightly yellow, oily liquid
Odor: Odor is like acetone and peppermint.
Boiling Point: 155C (311oF)
Melting Point: -31C (-24oF)
Vapor Pressure (mm Hg): 5 @ 26C (79oF)
Vapor Density (Air=1): 3.4
Specific Gravity: 0.95 @ 25C/4C
PH: No information found
Evaporation Rate (BuAc=1): 0.29
Solubility In Water: 15% in water @ 10C (50oF)
Percent Volatiles By Volume @ 21C (70oF): 100
===========================================================================
Fire and Explosion Hazard Data
===========================================================================
WARNING! FLAMMABLE LIQUID AND VAPOR. HARMFUL IF SWALLOWED, INHALED OR
ABSORBED THROUGH SKIN. AFFECTS CENTRAL NERVOUS SYSTEM, LIVER AND KIDNEYS.
CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT.
Flash Point: 43.9C (111oF) Auto-ignition Temperature: 420C (788oF)
Page 2 of 5
Upper Explosive Limit: 9.4
Lower Explosive Limit: 1.1
Extinguishing Media: Dry chemical, foam or carbon dioxide. Water spray may be used to keep fire exposed
containers cool, dilute spills to nonflammable mixtures, protect personnel attempting to stop leak and disperse
vapors.
Special Fire Fighting Proceedure: In the event of a fire, wear full protective clothing and NIOSH-approved self-
contained breathing apparatus with full face-piece operated in the pressure demand or other positive pressure mode.
Unusual Fire And Explosion Hazards:
Above flash point, vapor-air mixtures are explosive within flammable limits noted above. Vapors can flow along
surfaces to distant ignition sources and flash back. Contact with strong oxidizers may cause fire. Sealed containers
may rupture when heated. Sensitive to static discharge.
===========================================================================
Reactivity Data
===========================================================================
Stability: Stable under ordinary conditions of use and storage.
Cond To Avoid (Stability): Heat, flames, ignition sources and incompatibles.
Materials To Avoid: Strong oxidizing agents. May cause spontaneous ignition and violent reaction. May attack
plastics, resins and rubber.
Hazardous Decomp Products: Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Poly Occur: Will not occur.
===========================================================================
Health Hazard Data
===========================================================================
Health Rating: 2 ?Moderate
Flammability Rating: 2- Moderate
Reactivity Rating: 1 ?Slight
Contact Rating: 2 ?Moderate
Lab Protective Equipment: Goggles; Lab Coat; Vent Hood; Proper Gloves; Class B Extinguisher.
Storage Color Code: Red (Flammable)
Route Of Entry - Inhalation: Causes irritation to the respiratory tract. Symptoms may include coughing and
shortness of breath. High concentrations have a narcotic effect. Irritation effects normally prevent exposure high
enough to cause systemic effects.
Route Of Entry - Skin: Causes irritation to skin. Symptoms include redness, itching, and pain. May be absorbed
through the skin with possible systemic effects.
Route Of Entry - Ingestion: May produce abdominal pain and nausea. Aspiration into lungs can produce severe
lung damage and is a medical emergency. Other symptoms expected to parallel inhalation.
Route Of Entry ?Eyes: Vapors may cause irritation. Contact may cause corneal injury.
Explanation Carcinogenicity:
Signs/Symptoms Of Overexp: Prolonged or repeated exposure may cause skin rash or dermatitis. Damage to the
liver and kidneys may occur.
Med Cond Aggravated By Exp: Persons with pre-existing skin, eye or central nervous system disorders, or
impaired liver, kidney, or pulmonary function may be more susceptible to the effects of this substance.
Emergency/First Aid Proceedure: Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Call a physician.
Ingestion: Give large amounts of water to drink. Never give anything by mouth to an unconscious person, Get
medical attention.
Skin Contact: In case of contact, immediately flush skin with plenty of water for at least 15 minutes while
removing contaminated clothing and shoes. Wash clothing before reuse. Call a physician.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids
occasionally. Get medical attention immediately.
Note to Physician: In small ingestions, the major concern is aspiration and gastrointestinal decontamination is not
recommended. With larger ingestions, there is potential for systemic toxicity from gastrointestinal absorption and
decontamination is suggested, keeping in mind that aspiration is still a concern.
===========================================================================
Precautions for Safe Handling and Use
===========================================================================
Page 3 of 5
Steps If Material Released/Spill: Ventilate area of leak or spill. Remove all sources of ignition. Wear appropriate
personal protective equipment as specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected
personnel from entering. Contain and recover liquid when possible. Use non-sparking tools and equipment. Collect
liquid in an appropriate container or absorb with an inert material (e.g., vermiculite, dry sand, earth), and place in a
chemical waste container. Do not use combustible materials, such as saw dust. Do not flush to sewer! If a leak or
spill has not ignited, use water spray to disperse the vapors, to protect personnel attempting to stop leak, and to
flush spills away from exposures. US Regulations (CERCLA) require reporting spills and releases to soil, water and
air in excess of reportable quantities. The toll free number for the US Coast Guard National Response Center is
(800) 424-8802.
Precautions-Handling/Storing: Protect against physical damage. Store in a cool, dry well-ventilated location,
away from any area where the fire hazard may be acute. Outside or detached storage is preferred. Separate from
incompatibles. Containers should be bonded and grounded for transfers to avoid static sparks. Storage and use areas
should be No Smoking areas. Use non-sparking type tools and equipment, including explosion proof ventilation.
Containers of this material may be hazardous when empty since they retain product residues (vapors, liquid);
observe all warnings and precautions listed for the product.
Other Precautions:
===========================================================================
Control Measures
===========================================================================
Respiratory Protection (NIOSH Approved): If the exposure limit is exceeded, a half-face organic vapor respirator
may be worn for up to ten times the exposure limit or the maximum use concentration specified by the appropriate
regulatory agency or respirator supplier, whichever is lowest. A full-face piece organic vapor respirator may be worn
for up to 50 times the exposure limit or the maximum use concentration specified by the appropriate regulatory
agency or respirator supplier, whichever is lowest. For emergencies or instances where the exposure levels are not
known, use a full-face piece positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not
protect workers in oxygen-deficient atmospheres.
Ventilation: A system of local and/or general exhaust is recommended to keep employee exposures below the
Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of
the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGHIH
document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as
appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye
wash fountain and quick-drench facilities in word area.
===========================================================================
Toxicological Information
============================================================================Or
al rat LD50: 1620 mg/kg; Inhalation rat LC50: 8000ppm/4-hour; Skin rabbit LD50; 1 mL/kg; Irritation: eye rabbit,
Standard Draize: 20 mg, severe; skin rabbit, Open Draize: 500 mg, mild. Investigated as a tumorigen, mutagen and
reproductive effector.
Cancer List
-NTP Carcinogen-
Ingredient Known Anticipated IARC Category
Cyclohexanone No No 3
==========================================================================
Ecological Information
============================================================================
Environmental Fate: When released into the soil, this material is expected to readily biodegrade. When released
into the soil, this material is expected to quickly evaporate. When released into the soil, this material is expected to
leach into groundwater. When released into water, this material evaporates to a moderate extent. When released into
water, this material may biodegrade to a moderate extent. This material has an estimated bio-concentration factor
(BCF) of less than 100. This material is not expected to significantly bio-accumulate. When released into the air,
this material is expected to be readily degraded by reaction with photo-chemically produced hydroxyl radicals. When
released into the air, this material is expected to have a half-life between 1 and 10 days.
Environmental Toxicity: The LC50/96-hour values for fish are over 100 mg/1.
==========================================================================
Transportation Data
Page 4 of 5
===========================================================================
Domestic (Land, D.O.T.) International (Water, I.M.O.)
Proper Shipping Name: CYCLOHEXANONE Shipping Name: CYCLOHEXANONE
Hazard Class: 3 Hazard Class: 3.3
UN/NA: UN1915 UN/NA: UN1915
Packing Group: III Packing Group: III
Information reported for product/size: 425 LB Information reported for product/size: 425 LB
International (Air, I.C.A.O.)
Proper Shipping Name: CYCLOHEXANONE
Hazard Class: 3
UN/NA: UN1915
Packing Group: III
Information Reported for Product/size: 425 LB
===========================================================================
Regulatory Information
============================================================================C
hemical Inventory Status ?Part 1
Ingredient TSCA EC Japan Australia
Cyclohexanone (108-94-1) Yes Yes Yes Yes
Chemical Inventory Status ?Part 2
Ingredient Korea DSL NDSL Phil.
Cyclohexanone (108-94-1) Yes Yes Yes Yes
Federal, State & International Regulations ?Part 1
Ingredient RQ TPQ List Chemical Catg.
Cyclohexanone (108-94-1) No No No No
Federal, State & International Regulations ?Part 2
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8 (d)
Cyclohexanone (108-94-1) 5000 U057 No
Chemical Weapons Convention: No TSCA 12 (b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: Yes Pressure:: No Reactivity: No (Pure/Liquid)
Australian Hazchem Code: 3[Y]
Poison Schedule: No Information found.
WHMIS:
This MSDS has been prepared according to hazard criteria of the Controlled Products Regulations (CPR) and
MSDS contains all of the information requried by the CPR.
==========================================================================
Disposal Data
===========================================================================
Whatever cannot be saved for recovery or recycling should be handled as hazardous waste and sent to a RCRA
approved incinerator or disposed in a RCRA approved waste facility. Processing, use or contamination of this
product may change the waste management options. State and local disposal regulations may differ from federal
disposal regulations. Dispose of container and unused contents in accordance with federal, state and local
requirements.
===========================================================================
Label Data
===========================================================================
Common Name: CYCLOHEXANONE
Page 5 of 5
Label Hazard Warning: WARNING! FLAMMABLE LIQUID AND VAPOR. HARMFUL IF SWALLOWED,
INHALED OR ABSORBED THROUGH SKIN. AFFECTS CENTRAL NERVOUS SYSTEM, LIVER AND
KIDNEYS. CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT.
Label Precautions: Avoid contact with eyes, skin and clothing. Avoid breathing vapor or mist. Keep container
closed. Keep away from heat, sparks and flame. Wash thoroughly after handling. Use only with adequate
ventilation.
Label First Aid: If swallowed, give large amounts of water to drink. Never give anything by mouth to an
unconscious person. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is
difficult, give oxygen. In case of contact, immediately flush eyes or skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Wash clothing before reuse. In all cases call a physician.
Product Use: Laboratory Reagent.
Health Hazard: 2-Moderate
Fire Hazard: 2-Moderate
Reactivity Hazard: 1-Slight
Contact Rating: 2- Moderate
Protect Eye: Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash
fountain and quick-drench facilities in word area.
Protect Skin: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as
appropriate, to prevent skin contact.
Protect Respiratory (NIOSH Approved): If the exposure limit is exceeded, a half-face organic vapor respirator
may be worn for up to ten times the exposure limit or the maximum use concentration specified by the appropriate
regulatory agency or respirator supplier, whichever is lowest. A full-face piece organic vapor respirator may be worn
for up to 50 times the exposure limit or the maximum use concentration specified by the appropriate regulatory
agency or respirator supplier, whichever is lowest. For emergencies or instances where the exposure levels are not
known, use a full-face piece positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not
protect workers in oxygen-deficient atmospheres.
The information contained herein is based on data considered to be accurate. However, no warranty is expressed
regarding the accuracy of these data or the results to be obtained from the use thereof. It is the user's obligation to
determine the conditions of safe use of the product.
--Rev 2.1, 12/05, DH
|