ARDEX AF675
Chemwatch Material Safety Data Sheet
Issue Date: 13-Oct-2008 CHEMWATCH 17-8096
NC317ECP Version No:2.0
CD 2008/3 Page 1 of 20
Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME
ARDEX AF675
SYNONYMS
"contact adhesive"
PROPER SHIPPING NAME
ADHESIVES
PRODUCT USE
?The use of a quantity of material in an unventilated or confined space may result in
increased exposure and an irritating atmosphere developing. Before starting consider
control of exposure by mechanical ventilation. Contact adhesive for vinyl skirting
applications.
SUPPLIER
Company: Ardex Australia Pty Ltd
Address:
20 Powers Road
Seven Hills
NSW, 2147
AUS
Telephone: 1800 224 070
Fax: +61 2 9838 7817
CHEMWATCH HAZARD RATINGS
Flammability
Toxicity
Body Contact
Reactivity
Chronic
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4
Section 2 - HAZARDS IDENTIFICATION
STATEMENT OF HAZARDOUS NATURE
HAZARDOUS SUBSTANCE. DANGEROUS GOODS. According to the Criteria of NOHSC,
and the ADG Code.
POISONS SCHEDULE
S5
RISK SAFETY
?Highly flammable. ?Keep away from sources of ignition. No
smoking.
?Harmful if swallowed. ?Do not breathe gas/ fumes/ vapour/ spray.
?Irritating to eyes and skin. ?Use only in well ventilated areas.
?Harmful: danger of serious damage to ?Keep container in a well ventilated place.
health by prolonged exposure through
inhalation.
continued...
ARDEX AF675
Chemwatch Material Safety Data Sheet
Issue Date: 13-Oct-2008 CHEMWATCH 17-8096
NC317ECP Version No:2.0
CD 2008/3 Page 2 of 20
Section 2 - HAZARDS IDENTIFICATION
?Harmful to aquatic organisms may cause ?Avoid exposure - obtain special instructions
long- term adverse effects in the aquatic before use.
environment.
?Possible risk of harm to the unborn ?Do not empty into drains.
child.
?HARMFUL - May cause lung damage if ?To clean the floor and all objects
swallowed. contaminated by this material use water and
detergent.
?Vapours may cause drowsiness and ?Keep container tightly closed.
dizziness.
?Keep away from food drink and animal feeding
stuffs.
?In case of contact with eyes rinse with
plenty of water and contact Doctor or Poisons
Information Centre.
?If swallowed IMMEDIATELY contact Doctor or
Poisons Information Centre (show this
container or label).
?This material and its container must be
disposed of as hazardous waste.
Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS
NAME CAS RN %
toluene 108-88-3 0-50
hexane isomers 0-50
ketone solvent 0-50
n- hexane 110-54-3 <5
Section 4 - FIRST AID MEASURES
SWALLOWED
??If swallowed do NOT induce vomiting.
?If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain open
airway and prevent aspiration.
?Observe the patient carefully.
?Never give liquid to a person showing signs of being sleepy or with reduced awareness; i.e. becoming unconscious.
?Give water to rinse out mouth, then provide liquid slowly and as much as casualty can comfortably drink.
?Seek medical advice.
?Avoid giving milk or oils.
?Avoid giving alcohol.
?If spontaneous vomiting appears imminent or occurs, hold patient's head down, lower than their hips to help avoid
possible aspiration of vomitus.
EYE
?If this product comes in contact with the eyes:
?Wash out immediately with fresh running water.
?Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and moving the eyelids by
occasionally lifting the upper and lower lids.
?If pain persists or recurs seek medical attention.
?Removal of contact lenses after an eye injury should only be undertaken by skilled personnel.
SKIN
?If skin contact occurs:
continued...
ARDEX AF675
Chemwatch Material Safety Data Sheet
Issue Date: 13-Oct-2008 CHEMWATCH 17-8096
NC317ECP Version No:2.0
CD 2008/3 Page 3 of 20
Section 4 - FIRST AID MEASURES
?Immediately remove all contaminated clothing, including footwear.
?Flush skin and hair with running water (and soap if available).
?Seek medical attention in event of irritation.
INHALED
??If fumes or combustion products are inhaled remove from contaminated area.
?Other measures are usually unnecessary.
NOTES TO PHYSICIAN
?Any material aspirated during vomiting may produce lung injury. Therefore emesis should not be
induced mechanically or pharmacologically. Mechanical means should be used if it is considered
necessary to evacuate the stomach contents; these include gastric lavage after endotracheal
intubation. If spontaneous vomiting has occurred after ingestion, the patient should be monitored
for difficult breathing, as adverse effects of aspiration into the lungs may be delayed up to 48
hours.
Following acute or short term repeated exposures to toluene:
?Toluene is absorbed across the alveolar barrier, the blood/air mixture being 11.2/15.6 (at 37
degrees C.) The concentration of toluene, in expired breath, is of the order of 18 ppm following
sustained exposure to 100 ppm. The tissue/blood proportion is 1/3 except in adipose where the
proportion is 8/10.
?Metabolism by microsomal mono-oxygenation, results in the production of hippuric acid. This may
be detected in the urine in amounts between 0.5 and 2.5 g/24 hr which represents, on average 0.8
gm/gm of creatinine. The biological half-life of hippuric acid is in the order of 1-2 hours.
?Primary threat to life from ingestion and/or inhalation is respiratory failure.
?Patients should be quickly evaluated for signs of respiratory distress (eg cyanosis, tachypnoea,
intercostal retraction, obtundation) and given oxygen. Patients with inadequate tidal volumes or
poor arterial blood gases (pO2 <50 mm Hg or pCO2 > 50 mm Hg) should be intubated.
?Arrhythmias complicate some hydrocarbon ingestion and/or inhalation and electrocardiographic
evidence of myocardial damage has been reported; intravenous lines and cardiac monitors should be
established in obviously symptomatic patients. The lungs excrete inhaled solvents, so that
hyperventilation improves clearance.
?A chest x-ray should be taken immediately after stabilisation of breathing and circulation to
document aspiration and detect the presence of pneumothorax.
?Epinephrine (adrenaline) is not recommended for treatment of bronchospasm because of potential
myocardial sensitisation to catecholamines. Inhaled cardioselective bronchodilators (e.g. Alupent,
Salbutamol) are the preferred agents, with aminophylline a second choice.
?Lavage is indicated in patients who require decontamination; ensure use.
BIOLOGICAL EXPOSURE INDEX - BEI
These represent the determinants observed in specimens collected from a healthy worker exposed at
the Exposure Standard (ES or TLV):
Determinant Index Sampling Time Comments
o- Cresol in urine 0.5 mg/L End of shift B
Hippuric acid in urine 1.6 g/g creatinine End of shift B, NS
Toluene in blood 0.05 mg/L Prior to last shift of
workweek
NS: Non-specific determinant; also observed after exposure to other material
B: Background levels occur in specimens collected from subjects NOT exposed.
continued...
ARDEX AF675
Chemwatch Material Safety Data Sheet
Issue Date: 13-Oct-2008 CHEMWATCH 17-8096
NC317ECP Version No:2.0
CD 2008/3 Page 4 of 20
Section 5 - FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA
??Foam.
?Dry chemical powder.
?BCF (where regulations permit).
?Carbon dioxide.
?Water spray or fog - Large fires only.
FIRE FIGHTING
??Alert Fire Brigade and tell them location and nature of hazard.
?May be violently or explosively reactive.
?Wear breathing apparatus plus protective gloves.
?Prevent, by any means available, spillage from entering drains or water course.
?Consider evacuation (or protect in place).
?Fight fire from a safe distance, with adequate cover.
?If safe, switch off electrical equipment until vapour fire hazard removed.
?Use water delivered as a fine spray to control the fire and cool adjacent area.
?Avoid spraying water onto liquid pools.
?Do not approach containers suspected to be hot.
?Cool fire exposed containers with water spray from a protected location.
?If safe to do so, remove containers from path of fire.
When any large container (including road and rail tankers) is involved in a fire,
consider evacuation by 500 metres in all directions.
FIRE/EXPLOSION HAZARD
??Liquid and vapour are highly flammable.
?Severe fire hazard when exposed to heat, flame and/or oxidisers.
?Vapour may travel a considerable distance to source of ignition.
?Heating may cause expansion or decomposition leading to violent rupture of containers.
?On combustion, may emit toxic fumes of carbon monoxide (CO).
Combustion products include: carbon dioxide (CO2), other pyrolysis products typical of burning organic
material.
Contains low boiling substance: Closed containers may rupture due to pressure
buildup under fire conditions.
FIRE INCOMPATIBILITY
??Avoid contamination with oxidising agents i.e. nitrates, oxidising acids, chlorine bleaches, pool
chlorine etc. as ignition may result.
HAZCHEM: 3YE
Section 6 - ACCIDENTAL RELEASE MEASURES
EMERGENCY PROCEDURES
MINOR SPILLS
??Remove all ignition sources.
?Clean up all spills immediately.
?Avoid breathing vapours and contact with skin and eyes.
?Control personal contact by using protective equipment.
?Contain and absorb small quantities with vermiculite or other absorbent material.
?Wipe up.
?Collect residues in a flammable waste container.
continued...
ARDEX AF675
Chemwatch Material Safety Data Sheet
Issue Date: 13-Oct-2008 CHEMWATCH 17-8096
NC317ECP Version No:2.0
CD 2008/3 Page 5 of 20
Section 6 - ACCIDENTAL RELEASE MEASURES
MAJOR SPILLS
??Clear area of personnel and move upwind.
?Alert Fire Brigade and tell them location and nature of hazard.
?May be violently or explosively reactive.
?Wear breathing apparatus plus protective gloves.
?Prevent, by any means available, spillage from entering drains or water course.
?Consider evacuation (or protect in place).
?No smoking, naked lights or ignition sources.
?Increase ventilation.
?Stop leak if safe to do so.
?Water spray or fog may be used to disperse /absorb vapour.
?Contain spill with sand, earth or vermiculite.
?Use only spark-free shovels and explosion proof equipment.
?Collect recoverable product into labelled containers for recycling.
?Absorb remaining product with sand, earth or vermiculite.
?Collect solid residues and seal in labelled drums for disposal.
?Wash area and prevent runoff into drains.
?If contamination of drains or waterways occurs, advise emergency services.
EMERGENCY RESPONSE PLANNING GUIDELINES (ERPG)
The maximum airborne concentration below which it is believed that nearly all individuals could be exposed
for up to one hour WITHOUT experiencing or developing
life-threatening health effects is:
toluene 1000ppm
irreversible or other serious effects or symptoms which could impair an individual's ability to take
protective action is:
toluene 300ppm
other than mild, transient adverse effects without perceiving a clearly defined odour is:
toluene 50ppm
American Industrial Hygiene Association (AIHA)
Ingredients considered according to the following cutoffs
Very Toxic (T+) >= 0.1% Toxic (T) >= 3.0%
R50 >= 0.25% Corrosive (C) >= 5.0%
R51 >= 2.5%
else >= 10%
where percentage is percentage of ingredient found in the mixture
Personal Protective Equipment advice is contained in Section 8 of the MSDS.
Section 7 - HANDLING AND STORAGE
PROCEDURE FOR HANDLING
??Containers, even those that have been emptied, may contain explosive vapours.
?Do NOT cut, drill, grind, weld or perform similar operations on or near containers.
Contains low boiling substance:
Storage in sealed containers may result in pressure buildup causing violent rupture of containers not rated
appropriately.
?Check for bulging containers.
?Vent periodically
?Always release caps or seals slowly to ensure slow dissipation of vapours.
?DO NOT allow clothing wet with material to stay in contact with skin.
continued...
ARDEX AF675
Chemwatch Material Safety Data Sheet
Issue Date: 13-Oct-2008 CHEMWATCH 17-8096
NC317ECP Version No:2.0
CD 2008/3 Page 6 of 20
Section 7 - HANDLING AND STORAGE
?Avoid all personal contact, including inhalation.
?Wear protective clothing when risk of exposure occurs.
?Use in a well-ventilated area.
?Prevent concentration in hollows and sumps.
?DO NOT enter confined spaces until atmosphere has been checked.
?Avoid smoking, naked lights, heat or ignition sources.
?When handling, DO NOT eat, drink or smoke.
?Vapour may ignite on pumping or pouring due to static electricity.
?DO NOT use plastic buckets.
?Earth and secure metal containers when dispensing or pouring product.
?Use spark-free tools when handling.
?Avoid contact with incompatible materials.
?Keep containers securely sealed.
?Avoid physical damage to containers.
?Always wash hands with soap and water after handling.
?Work clothes should be laundered separately.
?Use good occupational work practice.
?Observe manufacturer's storing and handling recommendations.
?Atmosphere should be regularly checked against established exposure standards to ensure safe working conditions.
SUITABLE CONTAINER
??Packing as supplied by manufacturer.
?Plastic containers may only be used if approved for flammable liquid.
?Check that containers are clearly labelled and free from leaks.
?For low viscosity materials (i) : Drums and jerry cans must be of the non-removable head type. (ii) : Where a can
is to be used as an inner package, the can must have a screwed enclosure.
?For materials with a viscosity of at least 2680 cSt. (23 deg. C)
?For manufactured product having a viscosity of at least 250 cSt. (23 deg. C)
?Manufactured product that requires stirring before use and having a viscosity of at least 20 cSt (25 deg. C)
(i) : Removable head packaging;
(ii) : Cans with friction closures and
(iii) : low pressure tubes and cartridges may be used.
?Where combination packages are used, and the inner packages are of glass, there must be sufficient inert
cushioning material in contact with inner and outer packages
?In addition, where inner packagings are glass and contain liquids of packing group I there must be sufficient
inert absorbent to absorb any spillage, unless the outer packaging is a close fitting moulded plastic box and the
substances are not incompatible with the plastic.
STORAGE INCOMPATIBILITY
?Toluene:
?reacts violently with strong oxidisers, bromine, bromine trifluoride, chlorine, hydrochloric acid/ sulfuric acid
mixture, 1,3-dichloro-5,5-dimethyl-2,4-imidazolidindione, dinitrogen tetraoxide, fluorine, concentrated nitric acid,
nitrogen dioxide, silver chloride, sulfur dichloride, uranium fluoride, vinyl acetate
?forms explosive mixtures with strong acids, strong oxidisers, silver perchlorate, tetranitromethane
?is incompatible with bis-toluenediazo oxide
?attacks some plastics, rubber and coatings
?may generate electrostatic charges, due to low conductivity, on flow or agitation.
?Vigorous reactions, sometimes amounting to explosions, can result from the contact between aromatic rings and
strong oxidising agents.
?Aromatics can react exothermically with bases and with diazo compounds.
STORAGE REQUIREMENTS
??Store in original containers in approved flame-proof area.
?No smoking, naked lights, heat or ignition sources.
?DO NOT store in pits, depressions, basements or areas where vapours may be trapped.
?Keep containers securely sealed.
?Store away from incompatible materials in a cool, dry well ventilated area.
?Protect containers against physical damage and check regularly for leaks.
continued...
ARDEX AF675
Chemwatch Material Safety Data Sheet
Issue Date: 13-Oct-2008 CHEMWATCH 17-8096
NC317ECP Version No:2.0
CD 2008/3 Page 7 of 20
Section 7 - HANDLING AND STORAGE
?Observe manufacturer's storing and handling recommendations.
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EXPOSURE CONTROLS
Source Material TWA ppm TWA mg/m?STEL ppm STEL mg/m?br>
__________________ __________________ _______ _______ _______ _______
Australia Exposure toluene (Toluene) 50 191 150 574
Standards
Australia Exposure n- hexane (Hexane (n- 20 72
Standards Hexane))
EMERGENCY EXPOSURE LIMITS
Material Revised IDLH Value (mg/m3) Revised IDLH Value (ppm)
toluene 500
n- hexane 1, 100 [LEL]
NOTES
Values marked LEL indicate that the IDLH was based on 10% of the lower explosive limit
for safety considerations even though the relevant toxicological data indicated that
irreversible health effects or impairment of escape existed only at higher concentrations.
MATERIAL DATA
?For toluene:
Odour Threshold Value: 0.16-6.7 (detection), 1.9-69 (recognition)
NOTE: Detector tubes measuring in excess of 5 ppm, are available.
High concentrations of toluene in the air produce depression of the central nervous
system (CNS) in humans. Intentional toluene exposure (glue-sniffing) at maternally-
intoxicating concentration has also produced birth defects. Foetotoxicity appears at
levels associated with CNS narcosis and probably occurs only in those with chronic
toluene-induced kidney failure. Exposure at or below the recommended TLV-TWA is thought
to prevent transient headache and irritation, to provide a measure of safety for possible
disturbances to human reproduction, the prevention of reductions in cognitive responses
reported amongst humans inhaling greater than 40 ppm, and the significant risks of
hepatotoxic, behavioural and nervous system effects (including impaired reaction time and
incoordination). Although toluene/ethanol interactions are well recognised, the degree of
protection afforded by the TLV-TWA among drinkers is not known.
Odour Safety Factor(OSF)
OSF=17 (TOLUENE).
For n-hexane:
Odour Threshold Value: 65 ppm
NOTE: Detector tubes for n-hexane, measuring in excess of 100 ppm, are available
commercially.
Occupational polyneuropathy may result from exposures as low as 500 ppm (as hexane),
whilst nearly continuous exposures of 250 ppm have caused neurotoxic effects in animals.
Many literature reports have failed to distinguish hexane from n-hexane and on the
assumption that the commercial hexane contains 30% n-hexane, a worst case recommendation
for TLV is assumed to reduce the risk of peripheral neuropathies (due to the metabolites
2,5-heptanedione and 3,6-octanedione) and other adverse neuropathic effects.
Concurrent exposure to chemicals (including MEK) and drugs which induce hepatic liver
oxidative metabolism can reduce the time for neuropathy to appear.
Odour Safety Factor(OSF)
OSF=0.15 (n-HEXANE).
continued...
ARDEX AF675
Chemwatch Material Safety Data Sheet
Issue Date: 13-Oct-2008 CHEMWATCH 17-8096
NC317ECP Version No:2.0
CD 2008/3 Page 8 of 20
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
INGREDIENT DATA
N-HEXANE:
TOLUENE:
?These exposure guidelines have been derived from a screening level of risk
assessment and should not be construed as unequivocally safe limits. ORGS represent an 8-
hour time-weighted average unless specified otherwise.
CR = Cancer Risk/10000; UF = Uncertainty factor:
TLV believed to be adequate to protect reproductive health:
LOD: Limit of detection
Toxic endpoints have also been identified as:
D = Developmental; R = Reproductive; TC = Transplacental carcinogen
Jankovic J., Drake F.: A Screening Method for Occupational Reproductive
American Industrial Hygiene Association Journal 57: 641-649 (1996).
N-HEXANE:
TOLUENE:
?Exposure limits with "skin" notation indicate that vapour and liquid may be absorbed
through intact skin. Absorption by skin may readily exceed vapour inhalation exposure.
Symptoms for skin absorption are the same as for inhalation. Contact with eyes and mucous
membranes may also contribute to overall exposure and may also invalidate the exposure
standard.
TOLUENE:
?For toluene:
Odour Threshold Value: 0.16-6.7 (detection), 1.9-69 (recognition)
NOTE: Detector tubes measuring in excess of 5 ppm, are available.
High concentrations of toluene in the air produce depression of the central nervous
system (CNS) in humans. Intentional toluene exposure (glue-sniffing) at maternally-
intoxicating concentration has also produced birth defects. Foetotoxicity appears at
levels associated with CNS narcosis and probably occurs only in those with chronic
toluene-induced kidney failure. Exposure at or below the recommended TLV-TWA is thought
to prevent transient headache and irritation, to provide a measure of safety for possible
disturbances to human reproduction, the prevention of reductions in cognitive responses
reported amongst humans inhaling greater than 40 ppm, and the significant risks of
hepatotoxic, behavioural and nervous system effects (including impaired reaction time and
incoordination). Although toluene/ethanol interactions are well recognised, the degree of
protection afforded by the TLV-TWA among drinkers is not known.
Odour Safety Factor(OSF)
OSF=17 (TOLUENE).
N-HEXANE:
?For n-hexane:
Odour Threshold Value: 65 ppm
NOTE: Detector tubes for n-hexane, measuring in excess of 100 ppm, are available
commercially.
Occupational polyneuropathy may result from exposures as low as 500 ppm (as hexane),
whilst nearly continuous exposures of 250 ppm have caused neurotoxic effects in animals.
Many literature reports have failed to distinguish hexane from n-hexane and on the
assumption that the commercial hexane contains 30% n-hexane, a worst case recommendation
for TLV is assumed to reduce the risk of peripheral neuropathies (due to the metabolites
2,5-heptanedione and 3,6-octanedione) and other adverse neuropathic effects.
Concurrent exposure to chemicals (including MEK) and drugs which induce hepatic liver
oxidative metabolism can reduce the time for neuropathy to appear.
Odour Safety Factor(OSF)
OSF=0.15 (n-HEXANE).
continued...
ARDEX AF675
Chemwatch Material Safety Data Sheet
Issue Date: 13-Oct-2008 CHEMWATCH 17-8096
NC317ECP Version No:2.0
CD 2008/3 Page 9 of 20
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
PERSONAL PROTECTION
EYE
??Safety glasses with side shields.
?Chemical goggles.
?Contact lenses may pose a special hazard; soft contact lenses may absorb and
concentrate irritants. A written policy document, describing the wearing of lens or
restrictions on use, should be created for each workplace or task. This should include a
review of lens absorption and adsorption for the class of chemicals in use and an account
of injury experience. Medical and first-aid personnel should be trained in their removal
and suitable equipment should be readily available. In the event of chemical exposure,
begin eye irrigation immediately and remove contact lens as soon as practicable. Lens
should be removed at the first signs of eye redness or irritation - lens should be
removed in a clean environment only after workers have washed hands thoroughly. [CDC
NIOSH Current Intelligence Bulletin 59].
HANDS/FEET
??Wear chemical protective gloves, eg. PVC.
?Wear safety footwear or safety gumboots, eg. Rubber.
Suitability and durability of glove type is dependent on usage. Factors such as:
?frequency and duration of contact,
?chemical resistance of glove material,
?glove thickness and
?dexterity,
are important in the selection of gloves.
OTHER
??Overalls.
?PVC Apron.
?PVC protective suit may be required if exposure severe.
?Eyewash unit.
?Ensure there is ready access to a safety shower.
?Some plastic personal protective equipment (PPE) (e.g. gloves, aprons, overshoes) are
not recommended as they may produce static electricity.
RESPIRATOR
?Selection of the Class and Type of respirator will depend upon the level of breathing
zone contaminant and the chemical nature of the contaminant. Protection Factors (defined
as the ratio of contaminant outside and inside the mask) may also be important.
Breathing Zone Level Maximum Protection Half- face Respirator Full- Face Respirator
ppm (volume) Factor
1000 10 AX- AUS -
1000 50 - AX- AUS
5000 50 Airline * -
5000 100 - AX- 2
10000 100 - AX- 3
100+ Airline**
* - Continuous Flow ** - Continuous-flow or positive pressure demand.
The local concentration of material, quantity and conditions of use determine the type of
personal protective equipment required. For further information consult site specific
CHEMWATCH data (if available), or your Occupational Health and Safety Advisor.
ENGINEERING CONTROLS
?For flammable liquids and flammable gases, local exhaust ventilation or a process
enclosure ventilation system may be required. Ventilation equipment should be explosion-
resistant.
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ARDEX AF675
Chemwatch Material Safety Data Sheet
Issue Date: 13-Oct-2008 CHEMWATCH 17-8096
NC317ECP Version No:2.0
CD 2008/3 Page 10 of 20
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE
Light yellow highly flammable liquid with a typical hydrocarbon odour; does not mix with water.
PHYSICAL PROPERTIES
Liquid.
Does not mix with water.
Floats on water.
Molecular Weight: Not Applicable Boiling Range (?>40
C):
Melting Range (?Not Applicable
C): Specific Gravity (water =1): 0.83
Solubility in water (g/L): Immiscible pH (as supplied): Not Applicable
pH (1% solution): Not Applicable Vapour Pressure (kPa): Not Available
Volatile Component (%vol): Not Available Evaporation Rate: Not Available
Relative Vapour Density (air=1): Not Available Flash Point (?<- 20 (CC) (solvent)
C):
Lower Explosive Limit (%): Not Available Upper Explosive Limit (%): Not Available
Autoignition Temp (?Not Available
C): Decomposition Temp ( ?Not Available
C):
State: Liquid Viscosity: Not Available
Section 10 - CHEMICAL STABILITY AND REACTIVITY INFORMATION
CONDITIONS CONTRIBUTING TO INSTABILITY
??Presence of incompatible materials.
?Product is considered stable.
?Hazardous polymerisation will not occur.
For incompatible materials - refer to Section 7 - Handling and Storage.
Section 11 - TOXICOLOGICAL INFORMATION
POTENTIAL HEALTH EFFECTS
ACUTE HEALTH EFFECTS
SWALLOWED
?Accidental ingestion of the material may be harmful; animal experiments indicate that ingestion
of less than 150 gram may be fatal or may produce serious damage to the health of the individual.
Swallowing of the liquid may cause aspiration into the lungs with the risk of chemical pneumonitis;
serious consequences may result. (ICSC13733).
Considered an unlikely route of entry in commercial/industrial environments. The liquid may
produce gastrointestinal discomfort and may be harmful if swallowed. Ingestion may result in
nausea, pain and vomiting. Vomit entering the lungs by aspiration may cause potentially lethal
chemical pneumonitis.
EYE
?The liquid produces a high level of eye discomfort and is capable of causing pain and severe
conjunctivitis. Corneal injury may develop, with possible permanent impairment of vision, if not
promptly and adequately treated.
There is evidence that material may produce eye irritation in some persons and produce eye damage
24 hours or more after instillation. Severe inflammation may be expected with pain. There may be
continued...
ARDEX AF675
Chemwatch Material Safety Data Sheet
Issue Date: 13-Oct-2008 CHEMWATCH 17-8096
NC317ECP Version No:2.0
CD 2008/3 Page 11 of 20
Section 11 - TOXICOLOGICAL INFORMATION
damage to the cornea. Unless treatment is prompt and adequate there may be permanent loss of
vision. Conjunctivitis can occur following repeated exposure.
SKIN
?The material may cause moderate inflammation of the skin either following direct contact or
after a delay of some time. Repeated exposure can cause contact dermatitis which is characterised
by redness, swelling and blistering.
Skin contact with the material may damage the health of the individual; systemic effects may
result following absorption.
Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may produce
systemic injury with harmful effects. Examine the skin prior to the use of the material and ensure
that any external damage is suitably protected.
INHALED
?Inhalation of vapours may cause drowsiness and dizziness. This may be accompanied by sleepiness,
reduced alertness, loss of reflexes, lack of co-ordination, and vertigo.
Inhalation of high concentrations of gas/vapour causes lung irritation with coughing and nausea,
central nervous depression with headache and dizziness, slowing of reflexes, fatigue and inco-
ordination.
Inhalation of vapours or aerosols (mists, fumes), generated by the material during the course of
normal handling, may be damaging to the health of the individual.
The use of a quantity of material in an unventilated or confined space may result in increased
exposure and an irritating atmosphere developing.
Before starting consider control of exposure by mechanical ventilation.
CHRONIC HEALTH EFFECTS
?Harmful: danger of serious damage to health by prolonged exposure through inhalation.
This material can cause serious damage if one is exposed to it for long periods. It can be assumed
that it contains a substance which can produce severe defects. This has been demonstrated via both
short- and long-term experimentation.
Based on experience with animal studies, exposure to the material may result in toxic effects to
the development of the foetus, at levels which do not cause significant toxic effects to the
mother.
There has been some concern that this material can cause cancer or mutations but there is not
enough data to make an assessment.
Substance accumulation, in the human body, may occur and may cause some concern following repeated
or long-term occupational exposure.
Chronic inhalation or skin exposure to n-hexane may cause damage to nerve ends in extremities,
e.g. finger, toes with loss of sensation. Symptoms can progress for months even after removal of
exposure, and recovery may take years and may not be complete.
Intentional abuse (glue sniffing) or occupational exposure to toluene can result in chronic
habituation. Chronic abuse has caused inco-ordination, tremors of the extremeties (due to
widespread cerebrum withering), headache, abnormal speech, temporary memory loss, convulsions,
coma, drowsiness, reduced colour perception, blindness, nystagmus (rapid, involuntary eye
movements), hearing loss leading to deafness and mild dementia. Toluene addicts often display a
range of disease phenomena in their nervous systems. Toluene abuse can cause kidney disease but
occupational toluene exposures usually do not cause it. Chronic exposure to toluene can damage the
heart and the blood, especially causing heartbeat irregularities. High concentrations of toluene
can harm the unborn baby and the developing infant.
TOXICITY AND IRRITATION
?unless otherwise specified data extracted from RTECS - Register of Toxic Effects of Chemical Substances.
?The material may cause skin irritation after prolonged or repeated exposure and may produce on contact
skin redness, swelling, the production of vesicles, scaling and thickening of the skin.
For toluene:
Acute Toxicity
Humans exposed to intermediate to high levels of toluene for short periods of time experience adverse
continued...
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Issue Date: 13-Oct-2008 CHEMWATCH 17-8096
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Section 11 - TOXICOLOGICAL INFORMATION
central nervous system effects ranging from headaches to intoxication, convulsions, narcosis, and death.
Similar effects are observed in short-term animal studies.
Humans - Toluene ingestion or inhalation can result in severe central nervous system depression, and in
large doses, can act as a narcotic. The ingestion of about 60 mL resulted in fatal nervous system
depression within 30 minutes in one reported case.
Constriction and necrosis of myocardial fibers, markedly swollen liver, congestion and haemorrhage of the
lungs and acute tubular necrosis were found on autopsy.
Central nervous system effects (headaches, dizziness, intoxication) and eye irritation occurred following
inhalation exposure to 100 ppm toluene 6 hours/day for 4 days.
Exposure to 600 ppm for 8 hours resulted in the same and more serious symptoms including euphoria, dilated
pupils, convulsions, and nausea . Exposure to 10,000-30,000 ppm has been reported to cause narcosis and
death
Toluene can also strip the skin of lipids causing dermatitis
Animals - The initial effects are instability and incoordination, lachrymation and sniffles (respiratory
exposure), followed by narcosis. Animals die of respiratory failure from severe nervous system depression.
Cloudy swelling of the kidneys was reported in rats following inhalation exposure to 1600 ppm, 18-20
hours/day for 3 days
Subchronic/Chronic Effects:
Repeat doses of toluene cause adverse central nervous system effects and can damage the upper respiratory
system, the liver, and the kidney. Adverse effects occur as a result from both oral and the inhalation
exposures. A reported lowest-observed-effect level in humans for adverse neurobehavioral effects is 88 ppm.
Humans - Chronic occupational exposure and incidences of toluene abuse have resulted in hepatomegaly and
liver function changes. It has also resulted in nephrotoxicity and, in one case, was a cardiac sensitiser
and fatal cardiotoxin.
Neural and cerebellar dystrophy were reported in several cases of habitual "glue sniffing." An
epidemiological study in France on workers chronically exposed to toluene fumes reported leukopenia and
neutropenia. Exposure levels were not given in the secondary reference; however, the average urinary
excretion of hippuric acid, a metabolite of toluene, was given as 4 g/L compared to a normal level of 0.6
g/L
Animals - The major target organs for the subchronic/chronic toxicity of toluene are the nervous system,
liver, and kidney. Depressed immune response has been reported in male mice given doses of 105 mg/kg/day
for 28 days. Toluene in corn oil administered to F344 male and female rats by gavage 5 days/week for 13
weeks, induced prostration, hypoactivity, ataxia, piloerection, lachrymation, excess salivation, and body
tremors at doses 2500 mg/kg. Liver, kidney, and heart weights were also increased at this dose and
histopathologic lesions were seen in the liver, kidneys, brain and urinary bladder. The no-observed-adverse
effect level (NOAEL) for the study was 312 mg/kg (223 mg/kg/day) and the lowest-observed-adverse effect
level (LOAEL) for the study was 625 mg/kg (446 mg/kg/day) .
Developmental/Reproductive Toxicity
Exposures to high levels of toluene can result in adverse effects in the developing human foetus. Several
studies have indicated that high levels of toluene can also adversely effect the developing offspring in
laboratory animals.
Humans - Variable growth, microcephaly, CNS dysfunction, attentional deficits, minor craniofacial and limb
abnormalities, and developmental delay were seen in three children exposed to toluene in utero as a result
of maternal solvent abuse before and during pregnancy
Animals - Sternebral alterations, extra ribs, and missing tails were reported following treatment of rats
with 1500 mg/m3 toluene 24 hours/day during days 9-14 of gestation. Two of the dams died during the
exposure. Another group of rats received 1000 mg/m3 8 hours/day during days 1-21 of gestation. No maternal
deaths or toxicity occurred, however, minor skeletal retardation was present in the exposed fetuses. CFLP
Mice were exposed to 500 or 1500 mg/m3 toluene continuously during days 6-13 of pregnancy. All dams died at
the high dose during the first 24 hours of exposure, however none died at 500 mg/m3. Decreased foetal
weight was reported, but there were no differences in the incidences of skeletal malformations or anomalies
between the treated and control offspring.
Absorption - Studies in humans and animals have demonstrated that toluene is readily absorbed via the lungs
and the gastrointestinal tract. Absorption through the skin is estimated at about 1% of that absorbed by
the lungs when exposed to toluene vapor.
Dermal absorption is expected to be higher upon exposure to the liquid; however, exposure is limited by the
rapid evaporation of toluene .
Distribution - In studies with mice exposed to radiolabeled toluene by inhalation, high levels of
radioactivity were present in body fat, bone marrow, spinal nerves, spinal cord, and brain white matter.
continued...
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Issue Date: 13-Oct-2008 CHEMWATCH 17-8096
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Section 11 - TOXICOLOGICAL INFORMATION
Lower levels of radioactivity were present in blood, kidney, and liver. Accumulation of toluene has
generally been found in adipose tissue, other tissues with high fat content, and in highly vascularised
tissues .
Metabolism - The metabolites of inhaled or ingested toluene include benzyl alcohol resulting from the
hydroxylation of the methyl group. Further oxidation results in the formation of benzaldehyde and benzoic
acid. The latter is conjugated with glycine to yield hippuric acid or reacted with glucuronic acid to form
benzoyl glucuronide. o-cresol and p-cresol formed by ring hydroxylation are considered minor metabolites
Excretion - Toluene is primarily (60-70%) excreted through the urine as hippuric acid. The excretion of
benzoyl glucuronide accounts for 10-20%, and excretion of unchanged toluene through the lungs also
accounts for 10-20%. Excretion of hippuric acid is usually complete within 24 hours after exposure.
TOLUENE:
?unless otherwise specified data extracted from RTECS - Register of Toxic Effects of Chemical Substances.
TOXICITY IRRITATION
Oral (human) LDLo: 50 mg/kg Skin (rabbit):20 mg/24h- Moderate
Oral (rat) LD50: 636 mg/kg Skin (rabbit):500 mg - Moderate
Inhalation (human) TCLo: 100 ppm Eye (rabbit):0.87 mg - Mild
Inhalation (man) TCLo: 200 ppm Eye (rabbit): 2mg/24h - SEVERE
Inhalation (rat) LC50: >26700 ppm/1h Eye (rabbit):100 mg/30sec - Mild
Dermal (rabbit) LD50: 12124 mg/kg
?The material may cause skin irritation after prolonged or repeated exposure and may produce on contact
skin redness, swelling, the production of vesicles, scaling and thickening of the skin.
For toluene:
Acute Toxicity
Humans exposed to intermediate to high levels of toluene for short periods of time experience adverse
central nervous system effects ranging from headaches to intoxication, convulsions, narcosis, and death.
Similar effects are observed in short-term animal studies.
Humans - Toluene ingestion or inhalation can result in severe central nervous system depression, and in
large doses, can act as a narcotic. The ingestion of about 60 mL resulted in fatal nervous system
depression within 30 minutes in one reported case.
Constriction and necrosis of myocardial fibers, markedly swollen liver, congestion and haemorrhage of the
lungs and acute tubular necrosis were found on autopsy.
Central nervous system effects (headaches, dizziness, intoxication) and eye irritation occurred following
inhalation exposure to 100 ppm toluene 6 hours/day for 4 days.
Exposure to 600 ppm for 8 hours resulted in the same and more serious symptoms including euphoria, dilated
pupils, convulsions, and nausea . Exposure to 10,000-30,000 ppm has been reported to cause narcosis and
death
Toluene can also strip the skin of lipids causing dermatitis
Animals - The initial effects are instability and incoordination, lachrymation and sniffles (respiratory
exposure), followed by narcosis. Animals die of respiratory failure from severe nervous system depression.
Cloudy swelling of the kidneys was reported in rats following inhalation exposure to 1600 ppm, 18-20
hours/day for 3 days
Subchronic/Chronic Effects:
Repeat doses of toluene cause adverse central nervous system effects and can damage the upper respiratory
system, the liver, and the kidney. Adverse effects occur as a result from both oral and the inhalation
exposures. A reported lowest-observed-effect level in humans for adverse neurobehavioral effects is 88 ppm.
Humans - Chronic occupational exposure and incidences of toluene abuse have resulted in hepatomegaly and
liver function changes. It has also resulted in nephrotoxicity and, in one case, was a cardiac sensitiser
and fatal cardiotoxin.
Neural and cerebellar dystrophy were reported in several cases of habitual "glue sniffing." An
epidemiological study in France on workers chronically exposed to toluene fumes reported leukopenia and
neutropenia. Exposure levels were not given in the secondary reference; however, the average urinary
excretion of hippuric acid, a metabolite of toluene, was given as 4 g/L compared to a normal level of 0.6
g/L
Animals - The major target organs for the subchronic/chronic toxicity of toluene are the nervous system,
liver, and kidney. Depressed immune response has been reported in male mice given doses of 105 mg/kg/day
for 28 days. Toluene in corn oil administered to F344 male and female rats by gavage 5 days/week for 13
weeks, induced prostration, hypoactivity, ataxia, piloerection, lachrymation, excess salivation, and body
continued...
ARDEX AF675
Chemwatch Material Safety Data Sheet
Issue Date: 13-Oct-2008 CHEMWATCH 17-8096
NC317ECP Version No:2.0
CD 2008/3 Page 14 of 20
Section 11 - TOXICOLOGICAL INFORMATION
tremors at doses 2500 mg/kg. Liver, kidney, and heart weights were also increased at this dose and
histopathologic lesions were seen in the liver, kidneys, brain and urinary bladder. The no-observed-adverse
effect level (NOAEL) for the study was 312 mg/kg (223 mg/kg/day) and the lowest-observed-adverse effect
level (LOAEL) for the study was 625 mg/kg (446 mg/kg/day) .
Developmental/Reproductive Toxicity
Exposures to high levels of toluene can result in adverse effects in the developing human foetus. Several
studies have indicated that high levels of toluene can also adversely effect the developing offspring in
laboratory animals.
Humans - Variable growth, microcephaly, CNS dysfunction, attentional deficits, minor craniofacial and limb
abnormalities, and developmental delay were seen in three children exposed to toluene in utero as a result
of maternal solvent abuse before and during pregnancy
Animals - Sternebral alterations, extra ribs, and missing tails were reported following treatment of rats
with 1500 mg/m3 toluene 24 hours/day during days 9-14 of gestation. Two of the dams died during the
exposure. Another group of rats received 1000 mg/m3 8 hours/day during days 1-21 of gestation. No maternal
deaths or toxicity occurred, however, minor skeletal retardation was present in the exposed fetuses. CFLP
Mice were exposed to 500 or 1500 mg/m3 toluene continuously during days 6-13 of pregnancy. All dams died at
the high dose during the first 24 hours of exposure, however none died at 500 mg/m3. Decreased foetal
weight was reported, but there were no differences in the incidences of skeletal malformations or anomalies
between the treated and control offspring.
Absorption - Studies in humans and animals have demonstrated that toluene is readily absorbed via the lungs
and the gastrointestinal tract. Absorption through the skin is estimated at about 1% of that absorbed by
the lungs when exposed to toluene vapor.
Dermal absorption is expected to be higher upon exposure to the liquid; however, exposure is limited by the
rapid evaporation of toluene .
Distribution - In studies with mice exposed to radiolabeled toluene by inhalation, high levels of
radioactivity were present in body fat, bone marrow, spinal nerves, spinal cord, and brain white matter.
Lower levels of radioactivity were present in blood, kidney, and liver. Accumulation of toluene has
generally been found in adipose tissue, other tissues with high fat content, and in highly vascularised
tissues .
Metabolism - The metabolites of inhaled or ingested toluene include benzyl alcohol resulting from the
hydroxylation of the methyl group. Further oxidation results in the formation of benzaldehyde and benzoic
acid. The latter is conjugated with glycine to yield hippuric acid or reacted with glucuronic acid to form
benzoyl glucuronide. o-cresol and p-cresol formed by ring hydroxylation are considered minor metabolites
Excretion - Toluene is primarily (60-70%) excreted through the urine as hippuric acid. The excretion of
benzoyl glucuronide accounts for 10-20%, and excretion of unchanged toluene through the lungs also
accounts for 10-20%. Excretion of hippuric acid is usually complete within 24 hours after exposure.
N-HEXANE:
?unless otherwise specified data extracted from RTECS - Register of Toxic Effects of Chemical Substances.
TOXICITY IRRITATION
Oral (rat) LD50: 28710 mg/kg Eye(rabbit): 10 mg - Mild
Inhalation (human) TCLo: 190 ppm/8W
Inhalation (rat) LD50: 48000 ppm/4h
?The material may be irritating to the eye, with prolonged contact causing inflammation. Repeated or
prolonged exposure to irritants may produce conjunctivitis.
CARCINOGEN
toluene International Agency for Research on Group 3
Cancer (IARC) Carcinogens
REPROTOXIN
toluene ILO Chemicals in the electronics Reduced fertility
industry that have toxic effects on or sterility
reproduction
continued...
ARDEX AF675
Chemwatch Material Safety Data Sheet
Issue Date: 13-Oct-2008 CHEMWATCH 17-8096
NC317ECP Version No:2.0
CD 2008/3 Page 15 of 20
Section 11 - TOXICOLOGICAL INFORMATION
SKIN
toluene Australia Exposure Standards - Skin Notes Sk
Section 12 - ECOLOGICAL INFORMATION
Marine Pollutant: Not Determined
?DO NOT discharge into sewer or waterways.
Refer to data for ingredients, which follows:
TOLUENE:
?Hazardous Air Pollutant: Yes
?Fish LC50 (96hr.) (mg/l): 7.3- 22.8
?BCF<100: 13.2 (EELS
?log Kow (Sangster 1997): 2.73
?log Pow (Verschueren 1983): 2.69
?BOD5: 5%
?COD: 21%
?ThOD: 3.13
?Half- life Soil - High (hours): 528
?Half- life Soil - Low (hours): 96
?Half- life Air - High (hours): 104
?Half- life Air - Low (hours): 10
?Half- life Surface water - High (hours): 528
?Half- life Surface water - Low (hours): 96
?Half- life Ground water - High (hours): 672
?Half- life Ground water - Low (hours): 168
?Aqueous biodegradation - Aerobic - High (hours): 528
?Aqueous biodegradation - Aerobic - Low (hours): 96
?Aqueous biodegradation - Anaerobic - High (hours): 5040
?Aqueous biodegradation - Anaerobic - Low (hours): 1344
?Aqueous biodegradation - Removal secondary treatment - High (hours): 75%
?Photolysis maximum light absorption - High (nano- m): 268
?Photolysis maximum light absorption - Low (nano- m): 253.5
?Photooxidation half- life water - High (hours): 1284
?Photooxidation half- life water - Low (hours): 321
?Photooxidation half- life air - High (hours): 104
?Photooxidation half- life air - Low (hours): 10
?For toluene:
log Kow : 2.1-3
log Koc : 1.12-2.85
Koc : 37-260
log Kom : 1.39-2.89
Half-life (hr) air : 2.4-104
Half-life (hr) H2O surface water : 5.55-528
Half-life (hr) H2O ground : 168-2628
Half-life (hr) soil : <48-240
Henry's Pa m3 /mol: 518-694
Henry's atm m3 /mol: 5.94E-03
BOD 5 0.86-2.12, 5%
COD : 0.7-2.52,21-27%
ThOD : 3.13
BCF : 1.67-380
log BCF : 0.22-3.28
Environmental fate:
Transport: The majority of toluene evaporates to the atmosphere from the water and soil.It is moderately
continued...
ARDEX AF675
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Issue Date: 13-Oct-2008 CHEMWATCH 17-8096
NC317ECP Version No:2.0
CD 2008/3 Page 16 of 20
Section 12 - ECOLOGICAL INFORMATION
retarded by adsorption to soils rich in organic material (Koc = 259), therefore, transport to ground water
is dependent on the soil composition. In unsaturated topsoil containing organic material, it has been
estimated that 97% of the toluene is adsorbed to the soil and only about 2% is in the soil-water phase and
transported with flowing groundwater. There is little retardation in sandy soils and 2-13% of the toluene
was estimated to migrate with flowing water; the remainder was volatilised, biodegraded, or unaccounted
for. In saturated deep soils with no soil-air phase, about 48% may be transported with flowing groundwater.
Transformation/Persistence:
Air - The main degradation pathway for toluene in the atmosphere is reaction with photochemically produced
hydroxyl radicals. The estimated atmospheric half life for toluene is about 13 hours. Toluene is also
oxidised by reactions with atmospheric nitrogen dioxide, oxygen, and ozone, but these are minor degradation
pathways. Photolysis is not considered a significant degradative pathway for toluene
Soil - In surface soil, volatilisation to air is an important fate process for toluene. Biodegradation of
toluene has been demonstrated in the laboratory to occur with a half life of about 1 hour. In the
environment, biodegradation of toluene to carbon dioxide occurs with a typical half life of 1-7 days.
Water - An important fate process for toluene is volatilization, the rate of which depends on the amount of
turbulence in the surface water .The volatilisation of toluene from static water has a half life of 1-16
days, whereas from turbulent water the half life is 5-6 hours. Degradation of toluene in surface water
occurs primarily by biodegradation with a half life of less than one day under favorable conditions
(presence of microorganisms, microbial adaptation, and optimum temperature). Biodegradation also occurs in
shallow groundwater and in salt water at a reduced rate). No data are available on anaerobic degradation of
toluene in deep ground water conditions where aerobic degradation would be minimal .
Biota - Bioaccumulation in most organisms is limited by the metabolism of toluene into more polar compounds
that have greater water solubility and a lower affinity for lipids. Bioaccumulation in the food chain is
predicted to be low.
Ecotoxicity:
Toluene has moderate acute toxicity to aquatic organisms; several toxicity values are in the range of
greater than 1 mg/L and 100 mg/L.
Fish LC50 (96 h): fathead minnow (Pimephales promelas) 12.6-72 mg/l; Lepomis macrochirus 13-24 mg/l;
guppy (Poecilia reticulata) 28.2-59.3 mg/l; channel catfish (Ictalurus punctatus) 240 mg/l; goldfish
(Carassius auratus): 22.8-57.68 mg/l
Crustaceans LC50 (96 h): grass shrimp (Palaemonetes pugio) 9.5 ppm, crab larvae stage (Cancer magister) 28
ppm; shrimp (Crangon franciscorum) 4.3 ppm; daggerblade grass shrimp (Palaemonetes pugio) 9.5 mg/l
Algae EC50 (24 h): green algae (Chlorella vulgaris) 245 mg/l (growth); (72 h) green algae (Selenastrum
capricornutum) 12.5 mg/l (growth).
?DO NOT discharge into sewer or waterways.
N-HEXANE:
?Hazardous Air Pollutant: Yes
?Fish LC50 (96hr.) (mg/l): 4 (24hr)
?Algae IC50 (72hr.) (mg/l): 10
?log Kow (Sangster 1997): 3.9
?BOD5: 2.21
?COD: 0.04
?ThOD: 3.52
?Do NOT allow product to come in contact with surface waters or to intertidal areas below the mean high
water mark. Do not contaminate water when cleaning equipment or disposing of equipment wash-waters.
Wastes resulting from use of the product must be disposed of on site or at approved waste sites.
?For n-hexane:
log Kow : 3.17-3.94
BOD 5 if unstated: 2.21
COD : 0.04
ThOD : 3.52
Environmental fate:
Transport and Partitioning: The physical properties of n-hexane that affect its transport and partitioning
in the environment are: water solubility of 9.5 mg/L; log[Kow] (octanol/water partition coefficient),
estimated as 3.29; Henry's law constant, 1.69 atm-m3 mol; vapor pressure, 150 mm Hg at 25 C; and log[Koc]
in the range of 2.90 to 3.61. As with many alkanes, experimental methods for the estimation of the Koc
parameter are lacking, so that estimates must be made based on theoretical considerations.
continued...
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Issue Date: 13-Oct-2008 CHEMWATCH 17-8096
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Section 12 - ECOLOGICAL INFORMATION
The dominant transport process from water is volatilization. Based on mathematical models the half-life for
n-hexane in bodies of water with any degree of turbulent mixing (e.g., rivers) would be less than 3 hours.
For standing bodies of water (e.g., small ponds), a half-life no longer than one week (6.8 days) is
estimated based on the log octanol/water partition coefficient (i.e., log[Koc]) and the estimated log
sorption coefficient (i.e., log[Koc]) n-hexane is not expected to become concentrated in biota . A
calculated bioconcentration factor (BCF) of 453 for a fathead minnow further suggests a low potential for n-
hexane to bioconcentrate or bioaccumulate in trophic food chains.
In soil, the dominant transport mechanism for n-hexane present near the surface probably is volatilisation
(based on its Henry's law constant, water solubility, vapor pressure, and Koc). While its estimated Koc
values suggest a moderate ability to sorb to soil particles, n-hexane has a density (0.6603 g/mL at 20 C)
well below that of water and a very low water solubility of 9.5 mg/L. n-Hexane would, therefore, be viewed
as a light nonaqueous phase liquid (LNAPL), which would suggest a low potential for leaching into the lower
soil depths since the n-hexane would tend to float on the top of the saturated zone of the water table. n-
Hexane would generally stay near the soil surface and, if not appreciably sorbed into the soil matrix,
would be expected eventually to volatilise to the atmosphere. Exceptions would involve locations with
shallow groundwater tables where there were large spills of hexane products. In such cases, the n-hexane
could spread out to contaminant a large volume of soil materials.
Air: n-Hexane does not absorb ultraviolet (UV) light at 290 nm and is thus not expected to undergo direct
photolysis reactions. The dominant tropospheric removal mechanism for n-hexane is generally regarded to be
decomposition by hydroxyl radicals . Calculations assuming typical hydroxyl radical concentrations suggest
a half-life of approximately 2.9 days. While n-hexane can react with nitrogen oxides to produce ozone
precursors under controlled laboratory conditions, the smog-producing potential of n-hexane is very low
compared to that of other alkanes or chlorinated VOCs . Hydroxyl ion reactions in the upper troposphere,
therefore, are probably the primary mechanisms for n-hexane degradation in the atmosphere. As with most
alkanes, n-hexane is resistant to hydrolysis
Water: Although few data are available dealing explicitly with the biodegradation of n-hexane in water,
neither hydrolysis nor biodegradation in surface waters appears to be rapid compared with volatilization.
In surface waters, as in the atmosphere, alkanes such as n-hexane would be resistant to hydrolysis .
Biodegradation is probably the most significant degradation mechanism in groundwater. The ability of
Pseudomonas mendocina bacteria to metabolise n-hexane in laboratory microcosms simulating groundwater
conditions has been documented. Mixed bacterial cultures as well as pure cultures are documented as capable
of metabolizing n-hexane under aerobic conditions. In general, linear alkanes (such as n-hexane) are viewed
as the most readily biodegradable fractions in petroleum , particularly when oxygen is present in solution.
Once introduced into groundwater, n-hexane may be fairly persistent since its degradation by chemical
hydrolysis is slow and opportunities for biodegradation may be limited under anoxic conditions or where
nutrients such as nitrogen or phosphorus are in limited supply.
Sediment and Soil: the most important biodegradation processes involve the conversion of the n-hexane to
primary alcohols, aldehydes and, ultimately, into fatty acids. Similar processes are encountered with other
light hydrocarbons such as heptane. In general, unless the n-hexane is buried at some depth within a soil
or sediment, volatilisation is generally assumed to occur at a much more rapid rate than chemical or
biochemical degradation processes. Once introduced into deeper sediments, n-hexane may be fairly persistent.
Ecotoxicity:
Fish LC50 (96 h): Oncorhyncus mykiss 4.14 mg/l; Pimephales promelus 2.5 mg/l (flow through); Lepomis
macrochirus 4.12 mg/l
Daphnia EC50 (48 h): 3.87 mg/l.
?DO NOT discharge into sewer or waterways.
Section 13 - DISPOSAL CONSIDERATIONS
??Containers may still present a chemical hazard/ danger when empty.
?Return to supplier for reuse/ recycling if possible.
Otherwise:
?If container can not be cleaned sufficiently well to ensure that residuals do not
remain or if the container cannot be used to store the same product, then puncture
containers, to prevent re-use, and bury at an authorised landfill.
?Where possible retain label warnings and MSDS and observe all notices pertaining to the
product.
continued...
ARDEX AF675
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Issue Date: 13-Oct-2008 CHEMWATCH 17-8096
NC317ECP Version No:2.0
CD 2008/3 Page 18 of 20
Section 13 - DISPOSAL CONSIDERATIONS
Legislation addressing waste disposal requirements may differ by country, state and/ or
territory. Each user must refer to laws operating in their area. In some areas, certain
wastes must be tracked.
A Hierarchy of Controls seems to be common - the user should investigate:
?Reduction,
?Reuse
?Recycling
?Disposal (if all else fails)
This material may be recycled if unused, or if it has not been contaminated so as to make
it unsuitable for its intended use. If it has been contaminated, it may be possible to
reclaim the product by filtration, distillation or some other means. Shelf life
considerations should also be applied in making decisions of this type. Note that
properties of a material may change in use, and recycling or reuse may not always be
appropriate.
?DO NOT allow wash water from cleaning or process equipment to enter drains.
?It may be necessary to collect all wash water for treatment before disposal.
?In all cases disposal to sewer may be subject to local laws and regulations and these
should be considered first.
?Where in doubt contact the responsible authority.
?Recycle wherever possible.
?Consult manufacturer for recycling options or consult local or regional waste
management authority for disposal if no suitable treatment or disposal facility can be
identified.
?Dispose of by: Burial in a licenced land-fill or Incineration in a licenced apparatus
(after admixture with suitable combustible material).
?Decontaminate empty containers. Observe all label safeguards until containers are
cleaned and destroyed.
Section 14 - TRANSPORTATION INFORMATION
Labels Required: FLAMMABLE LIQUID
HAZCHEM: 3YE (ADG7)
UNDG:
Dangerous Goods 3 Subrisk: None
Class:
UN Number: 1133 Packing Group: II
Shipping Name:ADHESIVES containing flammable liquid
Air Transport IATA:
ICAO/IATA Class: 3 ICAO/IATA Subrisk: None
UN/ID Number: 1133 Packing Group: II
Special provisions: A3
Shipping Name: ADHESIVES CONTAINING FLAMMABLE LIQUID
Maritime Transport IMDG:
IMDG Class: 3 IMDG Subrisk: None
UN Number: 1133 Packing Group: II
EMS Number: F- E, S- D Special provisions: 944
Limited Quantities: 5L Marine Pollutant: Not Determined
Shipping Name: ADHESIVES containing flammable liquid
continued...
ARDEX AF675
Chemwatch Material Safety Data Sheet
Issue Date: 13-Oct-2008 CHEMWATCH 17-8096
NC317ECP Version No:2.0
CD 2008/3 Page 19 of 20
Section 15 - REGULATORY INFORMATION
POISONS SCHEDULE: S5
REGULATIONS
Ardex AF675 (CAS: None):
No regulations applicable
toluene (CAS: 108-88-3) is found on the following regulatory lists;
Australia - Australian Capital Territory - Environment Protection Regulation: Ambient environmental
standards (Domestic water supply - organic compounds)
Australia - Australian Capital Territory - Environment Protection Regulation: Pollutants entering
waterways taken to cause environmental harm (Aquatic habitat)
Australia - Australian Capital Territory Environment Protection Regulation Ecosystem maintenance -
Organic chemicals - Non-pesticide anthropogenic organics
Australia - Australian Capital Territory Environment Protection Regulation Pollutants entering
waterways - Domestic water quality
Australia Exposure Standards
Australia Hazardous Substances
Australia High Volume Industrial Chemical List (HVICL)
Australia Illicit Drug Reagents/Essential Chemicals - Category III
Australia Inventory of Chemical Substances (AICS)
Australia National Pollutant Inventory
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Appendix E (Part 2)
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Appendix F (Part 3)
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Appendix I
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Schedule 5
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Schedule 6
GESAMP/EHS Composite List of Hazard Profiles - Hazard evaluation of substances transported by ships
IMO IBC Code Chapter 17: Summary of minimum requirements
IMO MARPOL 73/78 (Annex II) - List of Noxious Liquid Substances Carried in Bulk
IMO Provisional Categorization of Liquid Substances - List 1: Pure or technically pure products
International Agency for Research on Cancer (IARC) Carcinogens
International Air Transport Association (IATA) Dangerous Goods Regulations
OECD Representative List of High Production Volume (HPV) Chemicals
United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances - Table
II
United Nations List of Precursors and Chemicals Frequently used in the Illicit Manufacture of Narcotic
Drugs and Psychotropic Substances Under International Control - Table II
WHO Guidelines for Drinking-water Quality - Guideline values for chemicals that are of health
significance in drinking-water
n-hexane (CAS: 110-54-3) is found on the following regulatory lists;
Australia Exposure Standards
Australia Hazardous Substances
Australia High Volume Industrial Chemical List (HVICL)
Australia Inventory of Chemical Substances (AICS)
Australia National Pollutant Inventory
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Schedule 5
GESAMP/EHS Composite List of Hazard Profiles - Hazard evaluation of substances transported by ships
IMO IBC Code Chapter 17: Summary of minimum requirements
IMO MARPOL 73/78 (Annex II) - List of Other Liquid Substances
IMO Provisional Categorization of Liquid Substances - List 2: Pollutant only mixtures containing at
least 99% by weight of components already assessed by IMO
International Air Transport Association (IATA) Dangerous Goods Regulations
International Council of Chemical Associations (ICCA) - High Production Volume List
OECD Representative List of High Production Volume (HPV) Chemicals
Section 16 - OTHER INFORMATION
REPRODUCTIVE HEALTH GUIDELINES
?Established occupational exposure limits frequently do not take into consideration
reproductive end points that are clearly below the thresholds for other toxic effects.
Occupational reproductive guidelines (ORGs) have been suggested as an additional
standard. These have been established after a literature search for the reproductive no-
observed-adverse effect-level (NOAEL) and the lowest-observed-adverse-effect-level
(LOAEL). In addition the US EPA's procedures for risk assessment for hazard
identification and dose-response assessment as applied by NIOSH were used in the creation
of such limits. Uncertainty factors (UFs) have also been incorporated.
Ingredient ORG UF Endpoint CR Adeq
TLV
toluene 9.6 mg/m3 10 D NA -
continued...
ARDEX AF675
Chemwatch Material Safety Data Sheet
Issue Date: 13-Oct-2008 CHEMWATCH 17-8096
NC317ECP Version No:2.0
CD 2008/3 Page 20 of 20
Section 16 - OTHER INFORMATION
n- hexane 176 mg/m3 NA NA NA Yes
?These exposure guidelines have been derived from a screening level of risk assessment
and should not be construed as unequivocally safe limits. ORGS represent an 8-hour time-
weighted average unless specified otherwise.
CR = Cancer Risk/10000; UF = Uncertainty factor:
TLV believed to be adequate to protect reproductive health:
LOD: Limit of detection
Toxic endpoints have also been identified as:
D = Developmental; R = Reproductive; TC = Transplacental carcinogen
Jankovic J., Drake F.: A Screening Method for Occupational Reproductive
American Industrial Hygiene Association Journal 57: 641-649 (1996).
?Classification of the preparation and its individual components has drawn on official
and authoritative sources as well as independent review by the Chemwatch Classification
committee using available literature references.
A list of reference resources used to assist the committee may be found at:
www.chemwatch.net/references.
?The (M)SDS is a Hazard Communication tool and should be used to assist in the Risk
Assessment. Many factors determine whether the reported Hazards are Risks in the
workplace or other settings. Risks may be determined by reference to Exposures Scenarios.
Scale of use, frequency of use and current or available engineering controls must be
considered.
This document is copyright. Apart from any fair dealing for the purposes of private study, research, review or
criticism, as permitted under the Copyright Act, no part may be reproduced by any process without written permission
from CHEMWATCH. TEL (+61 3) 9572 4700.
Issue Date: 13-Oct-2008
Print Date: 13-Oct-2008
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