DENTSPLY LUCITONE LIQUID
ChemWatch Material Safety Data Sheet CHEMWATCH 4993-47
Issue Date: Tue 27-Jul-2004 CD 2004/2 Page 1 of 16
Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME
DENTSPLY LUCITONE LIQUID
SYNONYMS
Part Nos. 684309 684315
688502
PROPER SHIPPING NAME
METHYL METHACRYLATE MONOMER, INHIBITED
PRODUCT USE
Denture acrylic resin.
SUPPLIER
Company: Dentsply (Australia) Pty Ltd
Address:
11-21 Gilby Road
Mount Waverley
VIC, 3149
AUS
Telephone: +61 03 9538 8240
Emergency Tel: 0413 830 239
Fax: 03 9538 8260
Section 2 - HAZARDS IDENTIFICATION
STATEMENT OF HAZARDOUS NATURE
HAZARDOUS SUBSTANCE. DANGEROUS GOODS.
According to the Criteria of NOHSC, and the ADG Code.
POISONS SCHEDULE
None
RISK
Highly flammable.
Irritating to eyes, respiratory system and skin.
May cause SENSITISATION by skin contact.
Inhalation, skin contact and/or ingestion may produce health damage*.
Cumulative effects may result following exposure*.
Limited evidence of a carcinogenic effect*.
Possible respiratory sensitiser*.
* (limited evidence)
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DENTSPLY LUCITONE LIQUID
ChemWatch Material Safety Data Sheet CHEMWATCH 4993-47
Issue Date: Tue 27-Jul-2004 CD 2004/2 Page 2 of 16
Section 2 - HAZARDS IDENTIFICATION ...
SAFETY
Keep away from sources of ignition. No smoking.
Do not breathe gas/fumes/vapour/spray.
Wear eye/face protection.
Use only in well ventilated areas.
Keep container in a well ventilated place.
Do not empty into drains.
Keep container tightly closed.
Take off immediately all contaminated clothing.
In case of contact with eyes, rinse with plenty of water and contact Doctor or
Poisons Information Centre.
If you feel unwell contact Doctor or Poisons Information Centre. (Show the label
if possible).
Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS
NAME CAS RN %
methyl methacrylate 80-62-6 >60
ethylene glycol dimethacrylate 97-90-5 <10
Section 4 - FIRST AID MEASURES
SWALLOWED
?If swallowed do NOT induce vomiting.
?If vomiting occurs, lean patient forward or place on left side (head-down
position, if possible) to maintain open airway and prevent aspiration.
?Observe the patient carefully.
?Never give liquid to a person showing signs of being sleepy or with reduced
awareness; i.e. becoming unconsciousness
?Give water to rinse out mouth, then provide liquid slowly and as much as
casualty can comfortably drink.
?Seek medical advice.
EYE
If this product comes in contact with the eyes:
?Immediately hold eyelids apart and flush the eye continuously with running
water.
?Ensure complete irrigation of the eye by keeping eyelids apart and away from
eye and moving the eyelids by occasionally lifting the upper and lower lids.
?Continue flushing until advised to stop by the Poisons Information Centre or a
doctor, or for at least 15 minutes.
?Transport to hospital or doctor without delay.
?Removal of contact lenses after an eye injury should only be undertaken by
skilled personnel.
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DENTSPLY LUCITONE LIQUID
ChemWatch Material Safety Data Sheet CHEMWATCH 4993-47
Issue Date: Tue 27-Jul-2004 CD 2004/2 Page 3 of 16
Section 4 - FIRST AID MEASURES ...
SKIN
If skin contact occurs:
?Immediately remove all contaminated clothing, including footwear
?Flush skin and hair with running water (and soap if available).
?Seek medical attention in event of irritation.
INHALED
?If fumes or combustion products are inhaled remove from contaminated area.
?Lay patient down. Keep warm and rested.
?Prostheses such as false teeth, which may block airway, should be removed,
where possible, prior to initiating first aid procedures.
?Apply artificial respiration if not breathing, preferably with a demand valve
resuscitator, bag-valve mask device, or pocket mask as trained. Perform CPR if
necessary.
?Transport to hospital, or doctor, without delay.
NOTES TO PHYSICIAN
Treat symptomatically.
Significant effects developing over a work-shift are not detected by
symptomatology, blood pressure, respiratory function testing, haemoglobin
and white cell count, urinalysis and blood chemistry. Effects may occur in
high concentration exposure groups with regard to serum glucose and blood
urea, nitrogen, cholesterol, albumin and total bilirubin values. Possible
alterations occur in skin and nervous system symptomatology, urinalysis
findings and serum triglycerides. Diagnostic signs taken as indicative of
methyl methacrylate-induced local neurotoxicity include sensory nerve
distal conduction velocities. These deficits appear to result from
diffusion of the substance into neurons, lysis of membrane lipids and
demyelination.
Section 5 - FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA
?Foam.
?Dry chemical powder.
?BCF (where regulations permit).
?Carbon dioxide.
?Water spray or fog - Large fires only.
FIRE FIGHTING
?Alert Fire Brigade and tell them location and nature of hazard.
?May be violently or explosively reactive.
?Wear full body protective clothing with breathing apparatus.
?Prevent, by any means available, spillage from entering drains or water
course.
?If safe, switch off electrical equipment until vapour fire hazard removed.
?Use water delivered as a fine spray to control fire and cool adjacent area.
?Avoid spraying water onto liquid pools.
?DO NOT approach containers suspected to be hot.
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DENTSPLY LUCITONE LIQUID
ChemWatch Material Safety Data Sheet CHEMWATCH 4993-47
Issue Date: Tue 27-Jul-2004 CD 2004/2 Page 4 of 16
Section 5 - FIRE FIGHTING MEASURES ...
?Cool fire exposed containers with water spray from a protected location.
?If safe to do so, remove containers from path of fire.
When any large container (including road and rail tankers) is involved in a fire,
consider evacuation by 1000 metres in all directions.
FIRE/EXPLOSION HAZARD
?Hot organic vapours or mist are capable of sudden spontaneous combustion when
mixed with air even at temperatures below their published autoignition
temperatures.
?The temperature of ignition decreases with increasing vapour volume and
vapour/air contact times and is influenced by pressure change.
?Ignition may occur under elevated-temperature process conditions especially in
processes performed under vacuum subjected to sudden ingress of air or in
processes performed at elevated pressure, where sudden escape of vapours or
mists to the atmosphere occurs.
Combustion products include
carbon dioxide (CO2)
nitrogen oxides (NOx)
other pyrolysis products typical of burning organic material
?Liquid and vapour are highly flammable.
?Severe fire hazard when exposed to heat, flame and/or oxidisers.
?Vapour may travel a considerable distance to source of ignition.
?Heating may cause expansion or decomposition leading to violent rupture of
containers.
?On combustion, may emit toxic fumes of carbon monoxide (CO).
FIRE INCOMPATIBILITY
Avoid contamination with oxidising agents i.e. nitrates, oxidising acids,
chlorine bleaches, pool chlorine etc. as ignition may result
?Polymerisation may occur at elevated temperatures.
?Polymerisation may be accompanied by generation of heat as exotherm.
?Process is self accelerating as heating causes more rapid polymerisation.
?Exotherm may cause boiling with generation of acrid, toxic and flammable
vapour.
?Polymerisation and exotherm may be violent if contamination with strong acids,
amines or catalysts occurs.
?Polymerisation and exotherm of material in bulk may be uncontrollable and
result in rupture of storage tanks.
?Polymerisation may occur if stabilising inhibitor becomes depleted by aging.
?Stabilising inhibitor requires dissolved oxygen to be present in liquid for
effective action.
?Specific storage requirements must be met for stability on ageing and
transport.
Contamination with polymerisation catalysts - peroxides, persulfates, oxidising
agents - also strong acids, strong alkalies, will cause polymerisation with
exotherm - generation of heat.
Polymerisation of large quantities may be violent - even explosive.
HAZCHEM
3[Y]E
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ChemWatch Material Safety Data Sheet CHEMWATCH 4993-47
Issue Date: Tue 27-Jul-2004 CD 2004/2 Page 5 of 16
Section 5 - FIRE FIGHTING MEASURES ...
Personal Protective Equipment
Glasses:
Chemical goggles.
Gloves:
1.PE/EVAL/PE 2.PVA 3.TEFLON
Respirator:
Type A Filter of sufficient capacity
Section 6 - ACCIDENTAL RELEASE MEASURES
EMERGENCY PROCEDURES
MINOR SPILLS
?Remove all ignition sources.
?Clean up all spills immediately.
?Avoid breathing vapours and contact with skin and eyes.
?Control personal contact by using protective equipment.
?Contain and absorb small quantities with vermiculite or other absorbent
material.
?Wipe up.
?Collect residues in a flammable waste container.
MAJOR SPILLS
Restrict access to area.
?Clear area of personnel and move upwind.
?Alert Fire Brigade and tell them location and nature of hazard.
?May be violently or explosively reactive.
?Wear breathing apparatus plus protective gloves.
?Prevent, by any means available, spillage from entering drains or water
course.
?Consider evacuation (or protect in place).
?No smoking, naked lights or ignition sources.
?Increase ventilation.
?Stop leak if safe to do so.
?Water spray or fog may be used to disperse /absorb vapour.
?Contain spill with sand, earth or vermiculite.
?Use only spark-free shovels and explosion proof equipment.
?Collect recoverable product into labelled containers for recycling.
?Absorb remaining product with sand, earth or vermiculite.
?Collect solid residues and seal in labelled drums for disposal.
?Wash area and prevent runoff into drains.
?If contamination of drains or waterways occurs, advise emergency services.
PROTECTIVE ACTIONS FOR SPILL
WARNING
MAY POLYMERISE VIOLENTLY UNDER CERTAIN CONDITIONS.
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DENTSPLY LUCITONE LIQUID
ChemWatch Material Safety Data Sheet CHEMWATCH 4993-47
Issue Date: Tue 27-Jul-2004 CD 2004/2 Page 6 of 16
Section 6 - ACCIDENTAL RELEASE MEASURES ...
PROTECTIVE ACTION ZONE
half
evacuation
downwind
direction
distance
down wind distance
wind isolation
direction distance
half
evacuation downwind
INITIAL direction distance
ISOLATION
ZONE
From IERG (Canada/Australia)
Isolation Distance 50 metres
Downwind Protection Distance 300 metres
IERG Number 18P
FOOTNOTES
1 PROTECTIVE ACTION ZONE is defined as the area in which people are at risk
of harmful exposure. This zone assumes that random changes in wind direction
confines the vapour plume to an area within 30 degrees on either side of the
predominant wind direction, resulting in a crosswind protective action distance
equal to the downwind protective action distance.
2 PROTECTIVE ACTIONS should be initiated to the extent possible, beginning with
those closest to the spill and working away from the site in the downwind
direction. Within the protective action zone a level of vapour concentration
may exist resulting in nearly all unprotected persons becoming incapacitated
and unable to take protective action and/or incurring serious or irreversible
health effects.
3 INITIAL ISOLATION ZONE is determined as an area, including upwind of the
incident, within which a high probability of localised wind reversal may
expose nearly all persons without appropriate protection to life-threatening
concentrations of the material.
4 SMALL SPILLS involve a leaking package of 200 litres (55 US gallons) or less,
such as a drum (jerrican or box with inner containers). Larger packages leaking
less than 200 litres and compressed gas leaking from a small cylinder are also
considered "small spills".
LARGE SPILLS involve many small leaking packages or a leaking package of
greater than 200 litres, such as a cargo tank, portable tank or a "one-tonne"
compressed gas cylinder.
5 Guide 129P is taken from the US DOT emergency response guide book.
6 IERG information is derived from CANUTEC - Transport Canada.
Personal Protective Equipment advice is contained in Section 8 of the MSDS.
Section 7 - HANDLING AND STORAGE
PROCEDURE FOR HANDLING
Handle gently.
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DENTSPLY LUCITONE LIQUID
ChemWatch Material Safety Data Sheet CHEMWATCH 4993-47
Issue Date: Tue 27-Jul-2004 CD 2004/2 Page 7 of 16
Section 7 - HANDLING AND STORAGE ...
?Avoid all personal contact, including inhalation.
?Wear protective clothing when risk of exposure occurs.
?Use in a well-ventilated area.
?Prevent concentration in hollows and sumps.
?DO NOT enter confined spaces until atmosphere has been checked.
?Avoid smoking, naked lights, heat or ignition sources.
?When handling, DO NOT eat, drink or smoke.
?Vapour may ignite on pumping or pouring due to static electricity.
?DO NOT use plastic buckets.
?Earth and secure metal containers when dispensing or pouring product.
?Use spark-free tools when handling.
?Avoid contact with incompatible materials.
?Keep containers securely sealed.
?Avoid physical damage to containers.
?Always wash hands with soap and water after handling.
?Work clothes should be laundered separately.
?Use good occupational work practice.
?Observe manufacturer's storing and handling recommendations.
?Atmosphere should be regularly checked against established exposure standards
to ensure safe working conditions.
DO NOT allow clothing wet with material to stay in contact with skin
SUITABLE CONTAINER
Packing as supplied by manufacturer. Plastic containers may only be used if
approved for flammable liquid. Check that containers are clearly labelled and
free from leaks.
?For low viscosity materials (i) : Drums and jerry cans must be of the
non-removable head type. (ii) : Where a can is to be used as an inner package,
the can must have a screwed enclosure.
?For materials with a viscosity of at least 2680 cSt. (23 deg. C)
?For manufactured product having a viscosity of at least 250 cSt. (23 deg. C)
?Manufactured product that requires stirring before use and having a viscosity
of at least 20 cSt (25 deg. C)
(i) : Removable head packaging;
(ii) : Cans with friction closures and
(iii) : low pressure tubes and cartridges may be used.
?Where combination packages are used, and the inner packages are of glass,
there must be sufficient inert cushioning material in contact with inner and
outer packages
?In addition, where inner packagings are glass and contain liquids of packing
group I there must be sufficient inert absorbent to absorb any spillage, unless
the outer packaging is a close fitting moulded plastic box and the substances
are not incompatible with the plastic.
STORAGE INCOMPATIBILITY
Segregate from
strong acids
strong alkalis
ammonia
amines
oxidisers
and
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ChemWatch Material Safety Data Sheet CHEMWATCH 4993-47
Issue Date: Tue 27-Jul-2004 CD 2004/2 Page 8 of 16
Section 7 - HANDLING AND STORAGE ...
strong oxidisers
Contamination with polymerisation catalysts - peroxides, persulfates, oxidising
agents - also strong acids, strong alkalies, will cause polymerisation with
exotherm - generation of heat.
Polymerisation of large quantities may be violent - even explosive.
STORAGE REQUIREMENTS
?Store in original containers in approved flame-proof area.
?No smoking, naked lights, heat or ignition sources.
?DO NOT store in pits, depressions, basements or areas where vapours may be
trapped.
?Keep containers securely sealed.
?Store away from incompatible materials in a cool, dry well ventilated area.
?Protect containers against physical damage and check regularly for leaks.
?Observe manufacturer's storing and handling recommendations.
?Storage requires stabilising inhibitor content and dissolved oxygen content to
be monitored. Refer to manufacturer's recommended levels.
?DO NOT overfill containers so as to maintain free head space above product.
?Blanketing or sparging with nitrogen or oxygen free gas will deactivate
stabiliser.
Easily peroxidisable. Products formed as a result of peroxidation are not only
safety hazards but may chemically alter the chemical behavior of the parent
compound.
Should have a warning label affixed bearing the date of receipt in the
laboratory and the date on which the container label is first opened, or
laboratory synthesised materials are the responsibility of the individual
chemist.
WARNING: This product may form peroxides which themselves are not Quantities of
uninhibited monomers exceeding 500 ml should not be stored for more than 24
hours.
The oxidation of iodide to iodine or the conversion of colourless
ferrothiocyanate to red ferrithiocyanate by peroxides are simple and convenient
tests for most peroxides.
Before distilling or evaporating a suitable polymerisation inhibitor should be
added. Leave at least 10% bottoms. Use a shield when evaporating or distilling
mixtures which may contain peroxidisable compounds. Store away from heat and
light. Particular attention should be paid to the adequacy of the closure on
storage containers. Peroxides may be removed by; (1) passing the material over a
column of ordinary activated alumina (care should be taken in disposal of the
activated alumina); (2) shaking with a concentrated solution of ferrous salt
(provided the carrier solvent is water-insoluble); (3) agitation with an
approximately equimolar mixture of ferrous sulfate and sodium bisulfate; (4)
commercial quantities may be treated with a 5% solution of aqueous sodium
carbonate.
Jackson et al: Control of Peroxizable Compounds; Safety in the Chemical
Laboratory, Journal of Chemical Education; Vol 47, 1970, pp A175-A188
When solvents have been freed from peroxides by percolation through a column of
activated alumina, the adsorbed peroxides must promptly be desorbed by treatment
with polar solvents, methanol or water, which must in turn be discarded
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ChemWatch Material Safety Data Sheet CHEMWATCH 4993-47
Issue Date: Tue 27-Jul-2004 CD 2004/2 Page 9 of 16
Section 7 - HANDLING AND STORAGE ...
safely.***
WARNING: Gradual decomposition in strong, sealed containers may lead to a
large pressure build-up and subsequent explosion.
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EXPOSURE CONTROLS
TLV TWA: 50 ppm, 205 mg/m? STEL: 100 ppm, 410 mg/m? A4 SENSITISER
NOTE: This substance has been classified by the ACGIH as A4 NOT classifiable as
causing Cancer in humans
ES TWA: 50 ppm, 208 mg/m? STEL: 100 ppm, 416 mg/m?(skin) SENSITISER
OES TWA: 50 ppm, 208 mg/m? STEL: 100 ppm, 416 mg/m?br>
REL TWA: 50 ppm; STEL: 75 ppm [Rohm & Haas]
MAK value: 50 ppm, 210 mg/m?br>
Designated S in List of MAK values: Danger of sensitization
MAK Category I Peak Limitation: For local irritants Allows excursions of twice
the MAK value for 5 minutes at a time, 8 times per shift.
MAK Group C: There is no reason to fear risk of damage to the developing embryo
when MAK and BAT values are observed.
MAK values, and categories and groups are those recommended within the
Federal Republic of Germany
Odour Threshold Value: 0.049 ppm (detection), 0.34 ppm (recognition)
IDLH Level: 1000 ppm
NOTE: Detector tubes measuring in excess of 50 ppm, are available.
Exposure limits with "skin" notation indicate that vapour and liquid may be
absorbed through intact skin. Absorption by skin may readily exceed vapour
inhalation exposure. Symptoms for skin absorption are the same as for
inhalation. Contact with eyes and mucous membranes may also contribute to
overall exposure and may also invalidate the exposure standard.
Concentrations as low as 125 ppm have produced irritation of the mucous
membranes of exposed workers. The recommended TLV-TWA is thought to be
sufficiently low to protect against discomfort from irritation and acute
systemic intoxication.
EXPOSURE STANDARDS FOR MIXTURE
"Worst Case" computer-aided prediction of vapour components/concentrations:
Composite Exposure Standard for Mixture (TWA) (mg/m?: 205 mg/m?br>
If the breathing zone concentration of ANY of the components listed below is
exceeded, "Worst Case" considerations deem the individual to be overexposed.
Component Breathing Zone ppm Breathing Zone mg/m?Mixture Conc: (%)
Component Breathing zone Breathing Zone Mixture Conc
(ppm) (mg/m? (%)
methyl methacrylate 50.00 205.0000 99.0
Operations which produce a spray/mist or fume/dust, introduce particulates to
the breathing zone.
If the breathing zone concentration of ANY of the components listed below is
exceeded, "Worst Case" considerations deem the individual to be overexposed.
At the "Composite Exposure Standard for Mixture" (TWA) (mg/m?: 99 mg/m?br>
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ChemWatch Material Safety Data Sheet CHEMWATCH 4993-47
Issue Date: Tue 27-Jul-2004 CD 2004/2 Page 10 of 16
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION ...
Component Breathing Zone Concentration
(mg/m? (%)
ethylene glycol dimethacrylate 2.0707 1.0
INGREDIENT DATA
METHYL METHACRYLATE:
PEL TWA: 100 ppm, 410 mg/m?[OSHA Z1]
TLV TWA: 50 ppm, 205 mg/m? STEL: 100 ppm, 410 mg/m? A4 SENSITISER
NOTE: This substance has been classified by the ACGIH as A4 NOT classifiable as
causing Cancer in humans
ES TWA: 50 ppm, 208 mg/m? STEL: 100 ppm, 416 mg/m?(skin) SENSITISER
OES TWA: 50 ppm, 208 mg/m? STEL: 100 ppm, 416 mg/m?br>
REL TWA: 50 ppm; STEL: 75 ppm [Rohm & Haas]
MAK value: 50 ppm, 210 mg/m?br>
Designated S in List of MAK values: Danger of sensitization
MAK Category I Peak Limitation: For local irritants Allows excursions of twice
the MAK value for 5 minutes at a time, 8 times per shift.
MAK Group C: There is no reason to fear risk of damage to the developing embryo
when MAK and BAT values are observed.
MAK values, and categories and groups are those recommended within the
Federal Republic of Germany
Odour Threshold Value: 0.049 ppm (detection), 0.34 ppm (recognition)
IDLH Level: 1000 ppm
NOTE: Detector tubes measuring in excess of 50 ppm, are available.
Exposure limits with "skin" notation indicate that vapour and liquid may be
absorbed through intact skin. Absorption by skin may readily exceed vapour
inhalation exposure. Symptoms for skin absorption are the same as for
inhalation. Contact with eyes and mucous membranes may also contribute to
overall exposure and may also invalidate the exposure standard.
Concentrations as low as 125 ppm have produced irritation of the mucous
membranes of exposed workers. The recommended TLV-TWA is thought to be
sufficiently low to protect against discomfort from irritation and acute
systemic intoxication.
ETHYLENE GLYCOL DIMETHACRYLATE:
CEL TWA: 1 mg/m?[compare WEEL-TWA* for multifunctional acrylates (MFAs)]
Exposure to MFAs has been reported to cause contact dermatitis in humans and
serious eye injury in laboratory animals. Exposure to some MFA-resin containing
aerosols has also been reported to cause dermatitis. As no assessment of the
possible effects of long-term exposure to aerosols was found, a conservative
Workplace Environmental Exposure Level (WEEL) was suggested by the American
Industrial Hygiene Association (AIHA).
Designated S in List of MAK values: Danger of sensitization
MAK values, and categories and groups are those recommended within the
Federal Republic of Germany
PERSONAL PROTECTION
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Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION ...
EYE
?Safety glasses with side shields
?Chemical goggles.
?Contact lenses pose a special hazard; soft lenses may absorb irritants and all
lenses concentrate them.
HANDS/FEET
Wear chemical protective gloves, eg. PVC.
Wear safety footwear or safety gumboots, eg. Rubber
NOTE: The material may produce skin sensitisation in predisposed individuals.
Care must be taken, when removing gloves and other protective equipment, to
avoid all possible skin contact.
OTHER
?Overalls.
?PVC Apron.
?PVC protective suit may be required if exposure severe.
?Eyewash unit.
?Ensure there is ready access to a safety shower.
GLOVE SELECTION INDEX
Glove selection is based on a modified presentation of the:
"Forsberg Clothing Performance Index".
The effect(s) of the following substance(s) are taken into account in the
computer-generated selection:
Substance
________________________________________
methyl methacrylate
PE/EVAL/PE A
PVA A
TEFLON A
BUTYL C
* CPI - Chemwatch Performance Index
A: Best Selection
B: Satisfactory; may degrade after 4 hours continuous immersion
C: Poor to Dangerous Choice for other than short term immersion
NOTE: As a series of factors will influence the actual performance of the glove,
a final selection must be based on detailed observation. -
* Where the glove is to be used on a short term, casual or infrequent basis,
factors such as "feel" or convenience (e.g. disposability), may dictate a choice
of gloves which might otherwise be unsuitable following long-term or frequent
use. A qualified practitioner should be consulted.
RESPIRATOR
Respiratory protection may be required when ANY "Worst Case" vapour-phase
concentration is exceeded (see Computer Prediction in "Exposure Standards").
Protection Factor (Min) Half-Face Respirator Full-face Respirator
10 x ES A-AUS -
A-PAPR-AUS -
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Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION ...
20 x ES - A-AUS
- A-PAPR-AUS
100 x ES - A-2
- A-PAPR-2
^ - Full-face
The local concentration of material, quantity and conditions of use determine
the type of personal protective equipment required. For further information
consult site specific CHEMWATCH data (if available), or your Occupational
Health and Safety Advisor.
ENGINEERING CONTROLS
Use in a well-ventilated area
For flammable liquids and flammable gases, local exhaust ventilation or a
process enclosure ventilation system may be required. Ventilation equipment
should be explosion-resistant.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE
Clear highly flammable liquid with a characteristic odour; does not mix
PHYSICAL PROPERTIES
Liquid.
Molecular Weight: Not Applicable Boiling Range (癈): Not Available
Melting Range (癈): -48 Specific Gravity (water=1): 0.94
Solubility in water (g/L): 1.5% pH (as supplied): Not Available
pH (1% solution): Not Available Vapour Pressure (kPa): 3.9
Volatile Component (%vol): Not Available Evaporation Rate: 3.1 BuAC = 1
Relative Vapour Density (air=1): 3.45 Flash Point (癈): 13 (toc)
Lower Explosive Limit (%): 2.1 Upper Explosive Limit (%): 12.5
Autoignition Temp (癈): 435 Decomposition Temp (癈): Not Available
State: Liquid
Section 10 - CHEMICAL STABILITY AND REACTIVITY INFORMATION
CONDITIONS CONTRIBUTING TO INSTABILITY
?Material contains a stabiliser / polymerisation inhibitor system that provides
workable but not indefinite shelf life.
?Storage at higher temperatures and long term storage may result in
polymerisation with solidification. In larger quantities e.g. 200 l drums, this
may result in generation of heat (exotherm) which may release highly irritating
hot vapour.
?DO NOT open hot exotherming drums - cool externally with water to avoid vapour
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Section 10 - CHEMICAL STABILITY AND REACTIVITY INFORMATION ...
release.
Polymerisation may occur at elevated temperatures and in the presence of
ignition sources.
Polymerisation may occur slowly at room temperature.
Section 11 - TOXICOLOGICAL INFORMATION
POTENTIAL HEALTH EFFECTS
ACUTE HEALTH EFFECTS
SWALLOWED
Considered an unlikely route of entry in commercial/industrial environments. If
swallowed, the liquid can produce stomach upset, nausea, pain and vomiting.
Vomit entering the lungs may cause chemical pneumonitis (inflammation of lungs)
which can cause death.
Oral doses of 5 ml/kg in dogs produce hypotension, signs of central
nervous system (CNS) depression, hepatic and renal degeneration and death
in respiratory arrest.
EYE
This material can cause eye irritation and damage in some persons.
The vapour is discomforting
SKIN
Skin contact with the material may damage the health of the individual; systemic
effects may result following absorption.
This material can cause inflammation of the skin on
contact in some persons.
The material may accentuate any pre-existing dermatitis condition
Entry into the blood-stream, through, for example, cuts, abrasions or lesions,
may produce systemic injury with harmful effects. Examine the skin prior to the
use of the material and ensure that any external damage is suitably protected.
Sensitisation reactions may appear suddenly after repeated
symptom free exposures
Reports of dental technicians, surgeons and manufacturing employees
with direct skin contact document paresthesias of the digits and mild
local axonal degeneration.
INHALED
Inhalation of vapours or aerosols (mists, fumes), generated by the material
during the course of normal handling, may be damaging to the health of the
individual.
The material can cause respiratory irritation in some persons. The body's
response to such irritation can cause further lung damage.
If exposure to highly concentrated vapour atmosphere is prolonged this may lead
to narcosis, unconsciousness, even coma and unless resuscitated - death.
Acute effects from inhalation of high vapour concentrations may be chest and
nasal irritation with coughing, sneezing, headache and even nausea.
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Section 11 - TOXICOLOGICAL INFORMATION ...
Workers in plants manufacturing methyl methacrylate have complained of
headaches, pains in the extremities, fatigue, sleep disturbance,
irritability and loss of memory. A Russian report associated disturbances
in the level of insulin, prolactin and circulating somatotropic hormone
in women to occupational exposure to methyl methacrylate.
Inhalation of 47 ppm in dogs produces hypotension, signs of central
nervous system (CNS) depression, hepatic and renal degeneration and death
in respiratory arrest.
CHRONIC HEALTH EFFECTS
Asthma-like symptoms may continue for months or even years after exposure to the
material ceases. This may be due to a non-allergenic condition known as reactive
airways dysfunction syndrome (RADS) which can occur following exposure to high
levels of highly irritating compound. Key criteria for the diagnosis of RADS
include the absence of preceding respiratory disease, in a non-atopic
individual, with abrupt onset of persistent asthma-like symptoms within minutes
to hours of a documented exposure to the irritant. A reversible airflow pattern,
on spirometry, with the presence of moderate to severe bronchial hyperreactivity
on methacholine challenge testing and the lack of minimal lymphocytic
inflammation, without eosinophilia, have also been included in the criteria for
diagnosis of RADS. RADS (or asthma) following an irritating inhalation is an
infrequent disorder with rates related to the concentration of and duration of
exposure to the irritating substance. Industrial bronchitis, on the other hand,
is a disorder that occurs as result of exposure due to high concentrations of
irritating substance (often particulate in nature) and is completely reversible
after exposure ceases. The disorder is characterised by dyspnea, cough and
mucous production.
There has been some concern that this material can cause cancer or mutations but
there is not enough data to make an assessment.
There is some evidence that inhaling this product is more likely to cause a
sensitisation reaction in some persons compared to the general population.
Skin contact with the material is more likely to cause a sensitisation reaction
in some persons compared to the general population.
Sensitisation may give severe responses to very low levels of exposure, i.e.
hypersensitivity. Sensitised persons should not be allowed to work in situations
where exposure may occur.
Sensitisation may result in allergic dermatitis responses including rash,
itching, hives or swelling of extremities.
Prolonged and repeated exposures can cause liver and kidney damage.
Hypotension induced by methyl methacrylate in surgical bone cement
has been followed by cardiac arrest with at least one fatality in
a patient undergoing surgery reported.
An increased mortality from colon and rectal cancer in white male
employees exposed for at least 10-months to acrylate monomer (including
methyl methacrylate) has been reported in one cohort but not in others
where acrylate exposures were controlled.
Incorporation of up to 2000 ppm methyl methacrylate in drinking water of
rats for up to two-years did not induce any treatment-related pathology
although subcutaneous and intraperitoneal implants of freshly polymerised
material for up to 39 months produced local fibrosarcoma.
Inhalation of methyl methacrylate by rats and mice of both sexes produced
inflammation of the nasal cavity and degeneration of the olfactory sensory
epithelium and epithelial hyperplasia of the nasal cavity in mice
(exposure occurred over two years)
continued...
DENTSPLY LUCITONE LIQUID
ChemWatch Material Safety Data Sheet CHEMWATCH 4993-47
Issue Date: Tue 27-Jul-2004 CD 2004/2 Page 15 of 16
Section 11 - TOXICOLOGICAL INFORMATION ...
Dentsply Lucitone Liquid
Not available. Refer to individual constituents.
unless otherwise specified data extracted from RTECS - Register of Toxic Effects
of Chemical Substances
METHYL METHACRYLATE:
IRRITATION TOXICITY
Skin (rabbit): 10000 mg/kg (open) Oral (rat) LD50: 7872 mg/kg
Eye (rabbit): 150 mg Inhalation (human) TCLo: 125 ppm
Inhalation (human) TCLo: 60 mg/m3(15 ppm)
Dermal (rabbit) LD50: > 5000 mg/kg
Inhalation (rat) LC50: 3750 ppm *
[* Manuf. Rohm & Haas] Dermal (rabbit) LD50: 35500 mg/kg *
The substance is classified by IARC as Group 3:
NOT classifiable as to its carcinogenicity to humans.
Evidence of carcinogenicity may be inadequate or limited in animal testing.
Based on the available oncogenicity data and without a better understanding of
the carcinogenic mechanism the Health and Environmental Review Division (HERD),
Office of Toxic Substances (OTS), of the US EPA previously concluded that all
chemicals that contain the acrylate or methacrylate moiety (CH2=CHCOO or
CH2=C(CH3)COO) should be considered to be a carcinogenic hazard unless shown
otherwise by adequate testing.
This position has now been revised and acrylates and methacrylates are no longer
de facto carcinogens.
ETHYLENE GLYCOL DIMETHACRYLATE:
IRRITATION TOXICITY
Nil reported Oral (rat) LD50: 3300 mg/kg
Intraperitoneal (rat) LD50: 2800 mg/kg
Oral (mouse) LD50: 2000 mg/kg
Based on the available oncogenicity data and without a better understanding of
the carcinogenic mechanism the Health and Environmental Review Division (HERD),
Office of Toxic Substances (OTS), of the US EPA previously concluded that all
chemicals that contain the acrylate or methacrylate moiety (CH2=CHCOO or
CH2=C(CH3)COO) should be considered to be a carcinogenic hazard unless shown
otherwise by adequate testing.
This position has now been revised and acrylates and methacrylates are no longer
de facto carcinogens.
Section 12 - ECOLOGICAL INFORMATION
DO NOT discharge into sewer or waterways.
Section 13 - DISPOSAL CONSIDERATIONS
?Consult manufacturer for recycling options and recycle where possible .
?Consult State Land Waste Management Authority for disposal.
?Incinerate residue at an approved site.
?Recycle containers if possible, or dispose of in an authorised landfill.
Puncture containers to prevent re-use and bury at an authorised landfill.
continued...
DENTSPLY LUCITONE LIQUID
ChemWatch Material Safety Data Sheet CHEMWATCH 4993-47
Issue Date: Tue 27-Jul-2004 CD 2004/2 Page 16 of 16
Section 13 - DISPOSAL CONSIDERATIONS ...
Section 14 - TRANSPORTATION INFORMATION
Shipping Name:
METHYL METHACRYLATE MONOMER, INHIBITED
Dangerous Goods Class: 3
UN/NA Number: 1247
ADR Number: 339
Packing Group: II
Labels Required: flammable liquid
Additional Shipping Information:
International Transport Regulations:
IMO: 3
HAZCHEM
3[Y]E
Section 15 - REGULATORY INFORMATION
POISONS SCHEDULE
None
Section 16 - OTHER INFORMATION
This document is copyright. Apart from any fair dealing for the purposes of
private study, research, review or criticism, as permitted under the Copyright
Act, no part may be reproduced by any process without written permission from
CHEMWATCH. TEL (+61 3) 9572 4700.
Issue Date: Tue 27-Jul-2004
Print Date: Wed 4-Aug-2004
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