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MATERIAL SAFETY DATA SHEET
Printing date 07/20/2009 Revision date 07/20/2009
* 1 Identification of Substance
Product Details
Trade Name: Nitrous oxide
Product No: G-3
Manufacturer/Supplier:
Linde Linde Gas Puerto Rico, Inc. Linde Canada Limited
575 Mountain Avenue Las Palmas Village 5860 Chedworth Way
Murray Hill, NJ 07974 USA Road No. 869, Street No. 7 Mississauga, Ontario L5R 0A2
ph: 908-464-8100 Catano, Puerto Rico 00962 ph: 905-501-1700
ph: 787-754-7445 .
Information Department:
Linde U.S. National Operations Center: 1-800-232-4726 (for US and Puerto Rico assistance)
Emergency Information:
US & Puerto Rico, CHEMTREC 24-HOUR EMERGENCY TELEPHONE NUMBER: 800-424-9300
In Canada, 24-HOUR EMERGENCY TELEPHONE NUMBER: 905-501-0802
* 2 Hazards Identification
Hazard Description:
Colorless nonflammable gas with slightly sweet odor. Oxidizer. Will accelerate combustion and
increase the risk of fire and explosion in combustible or flammable material. Inhalation of high
concentrations will cause anesthesia. May cause asphyxiation by exclusion of oxygen. Contents under
pressure. Use and store below 125.
Emergency Overview:
Warning! Contents under pressure. Oxidizing liquid and gas. Can cause suffocation. Repeated
exposure over time may have adverse reproductive effects, decrease neurobehavioral functions and
injure other organs. Intentional misuse of this product can be harmful or fatal. Repeated abuse of
nitrous oxide can have long-term health effects.
CLASSIFICATION SYSTEM:
NFPA Ratings (scale 0 - 4)
0 Health = 2
2 0 Fire = 0
Instability = 0
OX
The substance possesses oxidizing properties.
HMIS Ratings (scale 0 - 4)
HEALTH 1 Health = 1
Fire = 0
FIRE 0
Physical Hazard = 3
REACTIVITY 3
(Contd. on page 2)
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MATERIAL SAFETY DATA SHEET
Printing date 07/20/2009 Revision date 07/20/2009
Trade Name: Nitrous oxide
* 3 Composition/Data on Components
CAS No. Description
10024-97-2 Nitrous oxide
* 4 First aid measures
General Information:
If additional information is needed call the Linde emergency number (see section 1). PROMPT
MEDICAL ATTENTION IS MANDATORY IN ALL CASES OF OVEREXPOSURE. Seek medical advice.
If breathing has stopped or is labored, give assisted respirations. Supplemental oxygen may be
indicated. If the heart has stopped, trained personnel should begin cardiopulmonary resuscitation
immediately.
After Inhalation:
PROMPT MEDICAL ATTENTION IS MANDATORY IN ALL CASES OF OVEREXPOSURE TO
NITROUS OXIDE. RESCUE PERSONNEL SHOULD BE EQUIPPED WITH SELF-CONTAINED
BREATHING APPARATUS. Conscious persons should be assisted to an uncontaminated area and
inhale fresh air. Quick removal from the contaminated area is most important. Unconscious persons
should be moved to an uncontaminated area and, if breathing has stopped, administer artificial
resuscitation and supplemental oxygen. Further treatment should be symptomatic and supportive.
After skin contact:
None required for gas. For dermal contact or suspected frostbite, remove contaminated clothing and
flush affected areas with lukewarm water. DO NOT USE HOT WATER. A physican should see the
patient promptly if contact with the product has resulted in blistering of the dermal surface or in deep
tissue freezing.
After eye contact:
None required for gas. If frostbite is suspected, flush contaminated eye(s) with cool water for fifteen
minutes. Seek immediate medical attention.
After ingestion: Not required.
* 5 Fire fighting measures
Flammable Properties:
Nonflammable. Oxidizer. Can readily support or initiate combustion/ explosion of organic matter and
other oxidizable material. May decompose violently at temperatures above 1112 (600). Cylinder
may vent rapidly or rupture violently from pressure when involved in a fire situation.
Suitable extinguishing agents:
Use extinguishing media appropriate for the combustible material present. Use water spray to keep
cylinders cool.
Protective equipment:
Firefighters should wear respiratory protection (SCBA) and full turnout or Bunker gear.
Fire Fighting Instructions:
If possible, stop the flow of gas that is accelerating the fire. Continue to cool fire-exposed cylinders until
well after flames are extinguished.
(Contd. on page 3)
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MATERIAL SAFETY DATA SHEET
Printing date 07/20/2009 Revision date 07/20/2009
Trade Name: Nitrous oxide
* 6 Accidental release measures
Person-related safety precautions:
Immediately extinguish all ignition sources and evacuate all personnel from affected area. A leak near
combustible or flammable materials may represent a severe fire or explosion hazard. Stop or control
the leak, or remove the cylinder to the outside if it can be done without risk. Ventilate enclosed spaces.
Deny entry to persons not wearing appropriate protective equipment (see Section 8). If leak is in
user's equipment, be certain to purge piping with inert gas prior to attempting repairs. If leak is in
container or container valve, contact a HAZMAT specialist and the appropriate emergency telephone
number listed in Section 1 or call your closest Linde location.
* 7 Handling and storage
HANDLING:
Use only in well-ventilated areas. Do not drag, slide or roll cylinders. Use a suitable hand truck for
cylinder movement. Valve protection caps must remain in place unless container is secured with valve
outlet piped to use point. Use a pressure reducing regulator when connecting cylinder to lower
pressure piping or systems. Do not heat cylinder by any means to increase the discharge rate of
product from the container. Use a check valve or trap in the discharge line to prevent hazardous back
flow into the container. Do not insert any object (i.e. screwdriver) into valve cap openings as this can
damage the valve causing leakage.
Information about protection against explosions and fires:
Keep ignition sources away. Do not smoke. Pressurized container - protect from sunlight and do not
expose to temperatures exceeding 125. Do not pierce or burn container, even after use.
STORAGE:
Requirements to be met by storerooms and receptacles:
Protect cylinders from physical damage. Store in cool, dry, well-ventilated area of non-combustible
construction away from heavily trafficked areas and emergency exits. Do not allow the temperature
where cylinders are stored to exceed 125. Store containers upright and secure firmly to prevent
falling or being knocked over. Full and empty cylinders should be segregated. Use a "first in - first out"
inventory system to prevent full cylinders being stored for excessive periods of time. For additional
handling instructions, consult Compressed Gas Association Pamphlets P-1, G-8.1, G-8.2 and SB-6.
Security:
Store container in a secured area. Limit access to authorized personnel only. Report any incidents
involving thefts, misuse, or inventory shortages (missing containers or cylinders) to law enforcement
and the supplier. Security shall be provided in accordance with all local, state (provincial) and federal
regulations.
Due to increased misuse and abuse of nitrous oxide, handling storage precautions should be
implemented to prevent theft and improper use. The following recommendations may not include all
precautions which are necessary. Nitrous oxide systems should be installed in accordance with CGA
G-8.1, "Standards for Nitrous Oxide Systems at Consumer Sites." Keep full and empty nitrous oxide
containers and utilization equipment stored in a secured area. Allow only authorized personnel to
remove containers. Inventory and account for both full and empty containers and bulk product.
Promptly report any theft of nitrous oxide to the police and the supplier. Establish other procedures as
necessary to check for unusual use or loss of nitrous oxide.
* 8 Exposure controls and personal protection
Engineering Controls:
Local exhaust ventilation and enclosed processes as necessary to control air contaminants at or below
acceptable exposure guidelines.
(Contd. on page 4)
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MATERIAL SAFETY DATA SHEET
Printing date 07/20/2009 Revision date 07/20/2009
Trade Name: Nitrous oxide
Components with limit values that require monitoring at the workplace:
10024-97-2 Nitrous oxide
REL 46 mg/m? 25 ppm
TLV 90 mg/m? 50 ppm
PERSONAL PROTECTIVE EQUIPMENT:
Breathing equipment:
Positive pressure NIOSH-approved air-supplying respirator system (SCBA or airline/escape bottle) with
a full-face mask and at a minimum of Grade D air should be available for emergency use.
Protective gloves suitable for the job. Gloves must be free from grease or oil.
Hand/skin protection:
Eye/face protection: Safety glasses or chemical goggles.
Other/General Protection: Safety shoes, eyewash station.
* 9 Physical and chemical properties
GENERAL INFORMATION:
Gas
Form:
Colorless
Color:
Slightly sweetish
Odor:
CHANGE IN CONDITION:
Boiling point/Boiling range: 88.5癈 (191癋)
Not applicable
Flash point:
Ignition temperature:
Decomposition temperature: 600癈 (1112癋) (Becomes appreciable)
Explosion limits:
Product is a strong oxidizer.
Oxidizing properties
0.00184 g/cm?br>
Density at 20癈 (68癋):
* 10 Stability and reactivity
Thermal decomposition / Conditions to be avoided: Stable.
Materials to be avoided:
All flammable, organic and combustible materials. Avoid heat, sparks, flames and other ignition
sources. Nitrous oxide will serve as the oxidant for most flammable materials. Some flammables will
have a lower flammable limit in nitrous oxide than in pure oxygen. Powerfull reducing agents will react
violently.
Dangerous reactions: See above
Dangerous products of decomposition:
At elevated temperatures. Nitrous oxide decomposes into nitrogen and oxygen, the rate of
decomposition being appreciable at about 1112 (600). Nitrous oxide exposed to fire or other
intense heat source may decompose violently.
(Contd. on page 5)
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MATERIAL SAFETY DATA SHEET
Printing date 07/20/2009 Revision date 07/20/2009
Trade Name: Nitrous oxide
* 11 Toxicological information
ACUTE TOXICITY
LD/LC50 values that are relevant for classification:
Inhalative LC50/4 h 1.06 mg/l (rat)
PRIMARY IRRITANT EFFECT:
On the skin/eye: Not expected to cause irritation.
On inhalation:
Although nitrous oxide has adversely affected a variety of organs in both human and animal studies,
dose-related and casual relationships are poorly defined. Various studies indicate that nitrous oxide
may adversely affect the blood and blood forming organs, liver, kidneys, nervous system, reproductive
system, and fetus. The ACGIH TLV for nitrous oxide was established to protect against adverse
hematologic, nervous system and reproductive effects.
Dentists and dental assistants (> 8 H/week) heavily exposed to nitrous oxide exhibited higher hepatic
and renal disease rates than nonexposed dentists and their assistants. Neurological impairment from
nitrous oxide exposure has been reported at concentrations of several hundred to several thousand
ppm; however, decrements in human cognitive and psychomotor functions have been reported at
much lower concentrations.
Dentists exposed to nitrous oxide longer than 3000 hours within the prior 10 years exhibited neurologic
symptoms (i.e.: weakness, tingling, and numbness).
Additional toxicological information:
Reproductive toxicity has been observed in humans and animals following exposure to nitrous oxide in
concentrations in excess of the TLV. Fetal mortality increased at all concentrations in pregnant rats
exposed to 0, 100, 1000, or 15,000 ppm nitrous oxide (8 or 24 H/day for 5-9 days, 2-3 weeks of
pregnancy) and teratogenic effects (skeletal anomalies) were seen at 1,000 ppm.
Female workers directly exposed to waste anesthetic gases have exhibited a higher than expected
incidence of spontaneous abortion. Exposure to nitrous oxide alone resulted in a 50% increase in
congenital abnormalities and a 100% increase in spontaneous abortions in female dental assistants
compared with nonusers of nitrous oxide.
Three carcinogenic bioassays with nitrous oxide yielded negative results. Three epidemiologic studies
reported a small increase in the incidence of cancer in women, but not in men, occupationally exposed
to anesthetic gases.
* 12 Ecological information
Environmental impact:
Not classified as a Class I or Class II ozone depleting substance. No other data given.
13 Disposal considerations
PRODUCT:
Recommendation:
Do not attempt to dispose of residual waste or unused quantities. Return in the shipping container
PROPERLY LABELED, WITH ALL VALVE OUTLET PLUGS OR CAPS SECURED AND VALVE
PROTECTION CAP IN PLACE to Linde or authorized distributor for proper disposal.
(Contd. on page 6)
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MATERIAL SAFETY DATA SHEET
Printing date 07/20/2009 Revision date 07/20/2009
Trade Name: Nitrous oxide
UNCLEANED PACKAGING:
Recommendation: Same as above.
14 Transport information
DOT regulations:
2.2
Hazard class:
UN1070
Identification number:
-
Packing group:
Proper shipping name (technical name): NITROUS OXIDE
2.2+5.1
Label
Land transport ADR/RID (cross-border):
2 2O Gases
ADR/RID class:
25
Danger code (Kemler):
1070
UN-Number:
-
Packaging group:
2.2+5.1
Label:
1070 NITROUS OXIDE
Description of goods:
Maritime transport IMDG:
2.2
IMDG Class:
1070
UN Number:
2.2+5.1
Label
-
Packaging group:
F-C,S-W
EMS Number:
NITROUS OXIDE
Proper shipping name:
Air transport ICAO-TI and IATA-DGR:
2.2
ICAO/IATA Class:
1070
UN/ID Number:
2.2+5.1
Label
-
Packaging group:
NITROUS OXIDE
Proper shipping name:
(Contd. on page 7)
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MATERIAL SAFETY DATA SHEET
Printing date 07/20/2009 Revision date 07/20/2009
Trade Name: Nitrous oxide
UN "Model Regulation": UN1070, NITROUS OXIDE, 2.2 (5.1)
* 15 Regulations
SARA
Section 355 (extremely hazardous substances): Substance is not listed.
Section 313 (Specific toxic chemical listings): Substance is not listed.
TSCA (Toxic Substance Control Act):
The substance is listed.
10024-97-2 Nitrous oxide
PROPOSITION 65:
Chemicals known to cause cancer: Substance is not listed.
Chemicals known to cause reproductive toxicity for females: Substance is not listed.
Chemicals known to cause reproductive toxicity for males: Substance is not listed.
Chemicals known to cause developmental toxicity:
10024-97-2 Nitrous oxide
CARCINOGENICITY CATEGORIES:
EPA (Environmental Protection Agency) Substance is not listed.
NTP (National Toxicology Program) Substance is not listed.
TLV (Threshold Limit Value established by ACGIH)
10024-97-2 Nitrous oxide A4
NIOSH (National Institute for Occupational Safety and Health) Substance is not listed.
Product related hazard informations:
Safety phrases:
3/7 Keep container tightly closed in a cool place.
9 Keep container in a well-ventilated place.
* 16 Other information
This information is based on our present knowledge. However, this shall not constitute a guarantee for
any specific product features and shall not establish a legally valid contractual relationship.
Department Issuing MSDS: Linde Safety, Health, Environment and Quality
Contact: Refer to Linde web site for contact and product information at www.lindeus.com
Sources:
ABBREVIATIONS AND ACRONYMS:
ACGIH: American Conference of Governmental Industrial Hygienists
ADR/RID: Agreement on Dangerous Goods by Road/Regulation concerning the International Transport
of Goods by Rail
CAS: Chemical Abstracts Service
CGA: Compressed Gas Association
DOT: US Department of Transportation
EINECS: European Inventory of Existing Chemical Substances
GHS: Globally Harmonized System of Classification and Labelling of Chemicals
HMIS: Health Management Information System
IATA: International Air Transport Organization
IATA-DGR: Dangerous Goods Regulations by the International Air Transport Organization
ICAO: International Civil Aviation Organization
ICAO-TI: Technical Instructions by the International Civil Aviation Organization
IMDG: International Marine Code for Dangerous Goods
(Contd. on page 8)
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MATERIAL SAFETY DATA SHEET
Printing date 07/20/2009 Revision date 07/20/2009
Trade Name: Nitrous oxide
NFPA: National Fire Protection Association
OSHA: U.S. Occupational Safety & Health Administration
GENERAL DISCLAIMER
For terms and conditions, including limitation of liability, please refer to the purchase agreement in
effect between Linde LLC, Linde Merchant Production, Inc. or Linde Gas North America LLC (or any of
their affiliates and subsidiaries) and the purchaser.
DISCLAIMER OF EXPRESSED AND IMPLIED WARRANTIES
Although reasonable care has been taken in the preparation of this document, we extend no warranties
and make no representations as to the accuracy or completeness of the information contained herein,
and assume no responsibility regarding the suitability of this information for the user's intended
purposes or for the consequences of its use. Each individual should make a determination as to the
suitability of the information for their particular purpose(s).
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