MATERIAL SAFETY DATA SHEET HEXAMINE
PRODUCT CODE NUMBER(S): 3940-5
PRODUCT IDENTIFICATION Hazardous Decomposition Products: Formaldehyde,
NOx, CO, CO2, ammonia, hydrogen cyanide, n-nitroso com-
Chemical Name and Synonyms: Hexamine; pounds.
Hexamethylenetetramine
FIRE AND EXPLOSION DATA
Chemical Family: Tertiary amine
Chemical Formula: (CH2)6N4
Flammability: Flammable solid. Accumulation of fine dust
Product Use: Laboratory reagent particles can create explosion hazard, if electrostatic or
Manufacturer's Name and Address: other high-voltage spark, or other ignition source is present.
Caledon Laboratories Ltd. Extinguishing Media: Dry chemical, foam, carbon dioxide,
water spray or fog. Water spray or fog can also be used to
40 Armstrong Avenue
disperse dust or vapours and flush spills away from ignition
Georgetown, Ontario L7G 4R9
sources. Fight fire from safe distance and from upwind.
Telephone No: (905) 877-0101
FIrefighters must wear protective equipment (posi-
Fax No: (905) 877-6666 tive-pressure, full face-piece self-contained breathing
apparatus) and clothing (chemical splash suit) sufficient to
Emergency Telephone No: CANUTEC (613) 996-6666
prevent inhalation and contact.
HAZARDOUS INGREDIENTS OF MATERIALS Flash Point (Method Used): 250癈 (CC)
Autoignition Temperature: 410癈
Ingredients % TLV Units CAS No.
Upper Flammable Limit (% by volume): Not available
3
Hexamine >98 (TWA) 10 mg/m 100-97-0 Lower Flammable Limit (% by volume): Not available
Hazardous Combustion Products: Formaldehyde, NOx,
COx, ammonia, hydrogen cyanide, n-nitroso compounds.
PHYSICAL DATA Sensitivity to Impact: None idenitified
Physical State: Solid Sensitivity to Static discharge: As with most organic pow-
ders, mixtures of dust with air may be sensitive under
Odour and Appearance: White crystalline solid; odourless
certain conditions, when ignited by an electrostatic or other
Odour Threshold (ppm): Not applicable
high-voltage spark, or other ignition source.
Vapour Pressure (mm Hg): <0.01 mm Hg @ 20癈
TOXICOLOGICAL PROPERTIES AND HEALTH DATA
Vapour Density (Air = 1): Not applicable
Evaporation Rate: Not applicable
Toxicological Data:
Boiling Point (degrees C): Not available
LD50: (oral, mouse) 569 mg/kg; (sc, cat) 200 mg/kg
Melting Point (degrees C): 280癈 (sublimes)
LC50: Not available
pH: 8.5-9.5 (0.5M, aqueous, 20癈)
Specific Gravity: 1.27 @25癈
Effects of Acute Exposure to Product:
Coefficient of Water/Oil distribution: Log P=-3.68
Inhaled:. Irritating to mucous membranes and upper respi-
SHIPPING DESCRIPTION ratory tract, causing wheezing, coughing, and shortness of
breath.
UN: 1328 In contact with skin: Causes irritation. May be harmful if
T.D.G. Class: 4.1 absorbed. May cause allergic reaction. May decompose to
formaldehyde in presence of perspiration. Formaldehyde
Pkg. Group: III
may be carcinogenic.
REACTIVITY DATA In contact with eyes: No information available. May cause
irritation, with redness, tearing, itching.
Chemical Stability: Stable; hygroscopic. Ingested: Harmful. Ingestion of 1 to 2 gm may cause gas-
Incompatibility with other substances: May react vio- trointestinal upsets, with vomiting diarrhea and abdominal
lently or explosively with strong oxidizing agents. pain, and cystitis, inflammatory renal lesions and hematuria.
Hydrolyses in the presence of acids or acid environment.
Reacts violently with Na2O2. Excessive heat will cause de- Effects of Chronic Exposure to Product:
composition, releasing formaldehye and ammonia, both of
Prolonged or repeated skin contact can cause sensitization
which are toxic and irritating.
with urticaria or dermatitis. Previously sensitized individuals
Reactivity: Avoid heat, hot surfaces, sparks, open flame,
can experience asthma-like condition.
all other sources of ignition, incompatible materials, genera-
tion of dust.
HEXAMINE
MSDS
CODE: 3940-5
FIRST AID MEASURES
Carcinogenicity: No evidence of caracinogenicity in hu-
mans or animals, but formaldehyde, a decomposition
product, is a known carcinogen. Specific Measures:
Teratogenicity: No information available Eyes: Flush eyes thoroughly with gently running water,
Reproductive Effects: No information available holding eyelids open while flushing, for five to ten (5-10)
minutes, or until no trace of chemical remains. Wear gloves
Mutagenicity: Has been to shown to alter genetic material
to avoid contact during first aid procedures. Get medical at-
in drosophila.
tention.
Synergistic Products: None known
Skin: Remove contaminated clothing, including watches,
PREVENTIVE MEASURES rings, belts and shoes. Flush skin with plenty of running wa-
ter and non-abrasive soap until no trace of chemical
Engineering Controls: Local exhaust ventilation required. remains. Wear gloves to avoid contact during first aid pro-
Use grounded, non-sparking ventilation system and electri- cedures. Get medical attention.
cal equipment that does not provide a source of ignition. Inhalation: Remove to fresh air. Give oxygen and get
Respiratory Protection: Dust mask. Use only in a fume medical attention for any breathing difficulty.
hood. NIOSH/MSHA approved respirator for concentrations Ingestion: If victim is alert and NOT convulsing, rinse
above TLV. For higher or unknown concentrations, as in fire mouth thoroughly with water, give 2 to 4 glasses of water to
or spill conditions, full face-piece, positive-pressure drink and induce vomiting under medical supervision. When
self-contained breathing apparatus. vomiting occurs, have casualty lean forward to avoid breath-
Eye Protection: Chemical safety goggles. ing in of emesis. Rinse mouth and administer more water.
Get medical attention.
Skin Protection: Rubber gloves. Other protective clothing,
apron, sleeves, boots sufficient to prevent contact.
REFERENCES USED
Other Personal Protective Equipment: Safety shower
and eye-wash fountain in work area. CCINFO disc: MSDS's, May 2007
Leak and Spill Procedure: Restrict access to area of spill. Budavari: The Merck Index, 12th ed., 1997
Eliminate all sources of ignition and combustible materials.
Sax, Lewis: Hawley's Condensed Chemical Dictionary, 11th
Cleanup personnel must be thoroughly trained in the haz-
ed., 1987
ards of this chemical and its safe use, and must wear
protective equipment and clothing sufficient to prevent inha- Sax: Dangerous Properties of Industiral Materials, 5th ed.,
lation of dust or fumes, and contact with skin and eyes. 1979
Wet if necessary to avoid generating dust. Prevent from en-
Suppliers' Material Safety Data Sheets
tering sewers and waterways. Contain spill with inert
material (earth, sand, inert absorbent). Use non-sparking
ADDITIONAL INFORMATION
tools to collect material, in suitable, labelled, covered con-
tainers for disposal. Contaminated absorbent may pose the Date Issued: June 11, 1991
same hazards as the chemical; treat with caution. Flush
Revision: May 2010
area of spill with large amounts of running water.
MSDS: 3940-5
Waste Disposal: Follow all federal, provincial and local
Proposed WHMIS Designation: B4; D2A; D2B
regulations for disposal.
Handling Procedures and Equipment: FLAMMABLE,
TOXIC SOLID. Eliminate all sources of ignition and have all Prepared by: Caledon Laboratories Ltd. (905) 877-0101
engineering controls operating before handling. Personnel Caledon Laboratories Ltd. believes the information contained
working with this chemical must be thoroughly trained re- herein is reliable and accurate. Caledon makes no warranty
garding its hazards, and its safe use, and must wear with respect thereto and expressly disclaims all liability for reli-
appropriate protective equipment and clothing. Ground and
ance thereon. Such information is solely for your consider-
bond all equipment to prevent static charge accumulation.
ation, investigation, and verification.
Use non-sparking tools. Post "No Smoking" signs. Use
smallest amount possible for the purpose in an area with ap-
propriate ventilation. Avoid all contact with eyes, skin or
clothing. Avoid generating dust; use good-housekeeping
procedures to prevent accumulation of dust. Keep contain-
ers closed when not in use. Wash thoroughly after working
with this product.
Storage Requirements: Store in a cool, well-ventilated
area out of sun and away from all ignition sources. Keep
storage area free of combustible materials and incompatible
materials such as strong oxidizers. Storage facilities should
be made of fire-resistant materials, and have raised sills and
be trenched to safe location. Keep containers tightly closed.
Protect from damage and inspect frequently for signs of
damage or leaking.
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