MATERIAL SAFETY DATA SHEET
TESTOSTERONE
PADDOCK LABORATORIES, INC. EMERGENCY ASSISTANCE:
3940 QUEBEC AVENUE NORTH CHEMTREC 800-424-9300
MINNEAPOLIS, MINNESOTA 55427 202-483-7616
PHONE: (763)-546-4676 PADDOCK TECH. ASST. 800-328-5113
DATE PREPARED: 5-31-89 BY: Patrick L. Johnson
SECTION 1 - PRODUCT IDENTIFICATION AND HAZARDOUS COMPONENTS
PRODUCT: Testosterone
SYNONYMS: N/A
MOLECULAR FORMULA: C19 H28 O2 MOLECULAR WEIGHT: 288.43
CHEMICAL FAMILY: Androgen
INGREDIENT (CAS #) % OSHA PEL ACGIH TLV
Testosterone (58-22-0) 100 N/A N/A
SECTION 2 - PHYSICAL AND CHEMICAL CHARACTERISTICS
BOILING POINT: N/A VAPOR PRESSURE: N/A
MELTING POINT: 155o C VAPOR DENSITY: N/A
SPECIFIC GRAVITY: N/A EVAPORATION RATE: N/A
(WATER = 1) (BUTYL ACETATE = 1)
WATER SOLUBILITY: Practically insol. WATER REACTIVE: No
APPEARANCE AND ODOR: White or slightly creamy white crystals or crystalline powder; odorless.
SECTION 3 - FIRE AND EXPLOSION DATA
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FLASH POINT (METHOD): N/A AUTOIGNITION TEMPERATURE: N/A
FLAMMABLE LIMITS: LOWER: N/A UPPER: N/A
EXTINGUISHING MEDIA: Water spray, dry chemical, carbon dioxide, or foam.
SPECIAL FIRE FIGHTING PROCEDURES: Fire fighters should wear all protective gear including self-contained
breathing apparatus.
UNUSUAL FIRE AND EXPLOSION HAZARDS: This material is assumed to be combustible. When heated to
decomposition (as under fire conditions) it may emit toxic fumes.
SECTION 4 - REACTIVITY HAZARD DATA
STABILITY: Stable ( X ) Unstable ( )
INCOMPATIBILITY (MATERIALS TO AVOID): Oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS: When heated to decomposition it may emit toxic fumes.
HAZARDOUS POLYMERIZATION: May Occur ( ) Will Not Occur ( X )
SECTION 5 - HEALTH HAZARD DATA
TOXICITY: LD100: Intraperitoneal (rat) = 325 mg/kg
CARCINOGEN LISTED BY: NTP Yes ( ) No ( X )
IARC Yes ( X ) No ( )
OSHA Yes ( X ) No ( )
Other Yes ( X )* No ( )
* NOTE: There are rare reports of hepatocellular carcinoma in individuals receiving long term androgen therapy in
high doses.)
ROUTES OF ENTRY: Inhalation, ingestion, absorption.
HEALTH HAZARDS:
ACUTE: Eye, skin and/or respiratory tract irritation, nausea, vomiting.
CHRONIC: Possible hypersensitization; inhibition of testicular function in males; masculinization, nausea,
edema, menstrual irregularities in females; carcinogen.
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SIGNS AND SYMPTOMS OF OVEREXPOSURE: Eye, skin and/or respiratory tract irritation, nausea, vomiting.
MEDICAL CONDITIONS AGGRAVATED BY OVEREXPOSURE: Hypersensitivity to testosterone. Carcinoma
of prostate or breasts. Known or suspected neoplasia. Pregnant women should avoid exposure.
EMERGENCY FIRST AID PROCEDURES: If serious hypersensitivity reactions develop seek immediate medical
attention.
INHALATION: Remove to fresh air. Trained personnel should initiate artificial respiration if victim is not
breathing. Seek medical attention immediately.
EYES CONTACT: Flush with water for 15 minutes.
SKIN CONTACT: Wash with soap and water.
INGESTION: Rinse mouth out with water and seek medical attention immediately.
SECTION 6 - CONTROL AND PROTECTIVE MEASURES
RESPIRATORY PROTECTION: Approved dust respirator.
PROTECTIVE GLOVES: Rubber or latex.
EYE PROTECTION: Safety glasses or goggles recommended. Avoid wearing contact lenses when working with this
or any chemical due to the possibility of increased severity of eye injury.
VENTILATION: Local or mechanical ventilation recommended.
OTHER PROTECTIVE EQUIPMENT: Appropriate laboratory apparel.
HYGIENIC WORK PRACTICES: Do not eat, drink or smoke near this material. Wash any exposed skin areas after
handling. Wash contaminated clothing before reuse.
SECTION 7 - HANDLING AND STORAGE PRECAUTIONS
HANDLING PRECAUTIONS: Avoid contact with eyes, skin or clothing. Avoid breathing dust. Wash thoroughly
after handling. Wash contaminated clothing before reuse. Do not eat, drink or smoke near this material.
STORAGE PRECAUTIONS: Store in tight container and avoid exposure to excessive heat or humidity.
OTHER PRECAUTIONS: None.
MSDS - Testosterone Page 4 of 4
SECTION 8 - SPILL AND DISPOSAL PROCEDURES
STEPS TO BE TAKEN IN CASE OF SPILL OR DISCHARGE: Wear protective equipment (approved respirator,
gloves, goggles) and protect exposed skin. Vacuum or sweep up spillage and place in a tight container for disposal.
Ventilate spill area and wash down with soap and water. Wash thoroughly and wash contaminated clothing before
reuse.
WASTE DISPOSAL METHOD: Incinerate or landfill according to all local, state, federal, and environmental
regulations.
SECTION 9 - DISCLAIMER
The information contained in this Material Safety Data Sheet has been compiled from reliable sources and is believed to
be correct as of the date issued. It is the responsibility of the user to determine the appropriateness and applicability to
their situation. Paddock Laboratories, Inc. disclaims any expressed or implied warranty as to the accuracy of the above
information and shall not be held liable for any direct, incidental, or consequential damages from use or reliance on the
above information.
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DEFINITIONS OF ABBREVIATIONS USED:
ACGIH: American Conference of Governmental Industrial Hygienists
CAS: Chemical Abstract Service
IARC: Internal Agency for Research on Cancer
IDLH: Immediately Dangerous to Life or Health level
LD50: Median Lethal Dose
N/A: Not available
NTP: National Toxicology Program
OSHA: Occupational Safety and Health Administration
PEL: Permissible Exposure Limit
STEL: Short Term Exposure Limit
TLV: Threshold Limit Value
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