Emergency Assistance:
CHEMTREC庐 (24-hour)
1-800-424-9300
3940 Quebec Avenue North
Paddock Technical Assistance:
Minneapolis, MN 55427
1-800-328-5113
Tel: (763) 546-4676
MATERIAL SAFETY DATA SHEET
Benzphetamine Hydrochloride Tablets 50 mg
Revision Date: 03-07-07
SECTION 1: PRODUCT IDENTIFICATION
Benzphetamine Hydrochloride Tablets, 50 mg
Product Name
Benzphetamine Hydrochloride Tablets, 50 mg
Common Name/Trade Name
Paddock Laboratories, Inc.
Manufacturer
NA
Synonyms
d-N,a-Dimethyl-N-(phenylmethyl)-benzeneethanamine hydrochloride
Chemical Name
Phenethylamine derivative
Chemical Family
C17H21N路HCl
Chemical Formula
SECTION 2: HAZARDOUS INGREDIENTS
CHEMICAL NAME CAS# % OSHA PEL ACGIH TLV IDLH
Benzphetamine HCl 5411-22-3 NE NE NE NA
Microcrystalline Cellulose, NF 9004-34-6 NE NE NE
Lactose Monohydrate, NF 64044-51-5 NE NE NE
Sodium Starch Glycolate, NF 9063-38-1 NE NE NE
*Magnesium Stearate, NF 557-04-0 NE NE NE
*Colloidal Silicon Dioxide, NF 7631-86-9 NE NE NE
NA NE NE NE
Opadry II, 40L14336, Pink (film
coat)
* These ingredients are at concentrations of less than 1%.
SECTION 3: HAZARDS IDENTIFICATION
Paddock Laboratories, Inc. Page 1 of 6
Adverse effects may include increase in blood pressure; skin rash or
hives; swelling of feet and lower legs: trouble breathing; stroke or
impending stroke (severe headache, numbness on one side of body or
face); difficult, painful, or increased urination; talking, feeling, and
acting with uncontrolled excitement; mental depression; fast or
irregular heartbeat; chest pain; fainting; psychosis, (paranoia,
hallucinations); central nervous system stimulation (false sense of
Adverse Effects
well being, irritability, nervousness, restlessness, trembling or
shaking, trouble sleeping) followed by drowsiness, fatigue, or mental
depression; constipation; dizziness, dry mouth headache; nausea or
vomiting; stomach cramps or pain; blurred vision; changes in sexual
desire and ability; diarrhea; drowsiness, increased sweating; and
unpleasant taste. Possible allergic reaction to material if inhaled,
ingested or in contact with skin.
Possible eye, skin, gastrointestinal and/or respiratory tract irritation.
Potential Acute Health Effects
Possible hypersensitization, tolerance, and physical or psychological
Potential Chronic Health
dependence. Inhalation: May cause irritation. Remove to fresh air.
Effects
Pregnancy category X. Benzphetamine hydrochloride is not to be
used therapeutically during pregnancy because it may cause harm to
Pregnancy the fetus. Clinical reports in humans and studies in animals have
shown that amphetamines ( a related group of chemicals) cause birth
defects and abnormal development in the fetus.
SECTION 4: FIRST AID MEASURES
Skin Exposure May cause irritation. Flush with water.
May cause irritation. Flush immediately with copious amounts of water
Eye Exposure
for at least 15 minutes. Obtain emergency medical treatment.
Inhalation exposure is not expected to occur. If symptoms develop,
Inhalation
remove to a well ventilated area and seek medical attention.
May cause irritation and toxicity. Flush out mouth with water. This
material is absorbed from the gastrointestinal tract. Obtain emergency
Ingestion
medical treatment.
Treatment is symptomatic and supportive and may include the
following:
1. Do not induce vomiting. Administer activated charcoal.
Gastric emptying is not necessary if activated charcoal can be
given promptly.
2. Barbiturate sedatives or diazepam are sometimes used to
control excessive CNS stimulation.
Overdose Treatment
3. Treat severe hypertension with a parenteral vasodilator such as
phentolamine or nitroprusside.
4. Use beta-adrenergic blocking agent for control of tachycardia.
Use intravenous lidocaine for cardiac arrhythmia.
5. Use intravenous diazepam to control seizures; use phenytoin if
seizures are refractory to diazepam. When hyperthermia and
rhabdomyolysis are present, curarization may be required.
Paddock Laboratories, Inc. Page 2 of 6
6. Manage hypotension with intravenous fluids.
7. Monitor cardiovascular and respiratory function; monitor body
temperature. Use a mechanical respirator if necessary.
8. Protect patient from self-injury by use of restraints if necessary.
9. Dialysis and hemoperfusion are not effective. Acidification of
urine and forced diuresis may enhance elimination.
SECTION 5: FIRE / EXPLOSION HAZARDS & FIREFIGHTING MEASURES
NA
Flammability of the Product
NA
Auto-ignition Temperature
NA
Flash Points
Lower: NA Upper: NA
Flammable Limits (in air by volume, %)
Use extinguishing agent suitable for type of
surrounding fire.
Fire Extinguishing Equipment
Water Spray: OK
Foam: OK
Carbon Dioxide: OK
Dry Chemical: OK
None
Unusual Fire and Explosion Hazards
Explosion Hazards in presence of Various
NA
substances
For fires beyond the incipient stage, emergency
responders in the immediate hazard area should wear
bunker gear. When the potential chemical hazard is
unknown, in enclosed or confined spaces, or when
explicitly required by the DOT Emergency Response
Guidebook, a self-contained breathing apparatus
should be worn. In addition, wear other appropriate
protective equipment as conditions warrant (see
Firefighting Procedures
Section 8). Isolate immediate hazard area and keep
unauthorized personnel out. Contain spill if it can be
done with minimal risk. Move undamaged
containers from immediate hazard area if it can be
done with minimal risk. Cool equipment exposed to
fire with water, if it can be done with minimal risk.
SECTION 6: SPILL AND LEAK PROCEDURES
Clean area. Dispose in accordance with all Federal,
Spills
State and local regulations.
Paddock Laboratories, Inc. Page 3 of 6
SECTION 7: HANDLING AND STORAGE
As with all chemicals, avoid getting this product on
you or in you. Do not eat, drink or smoke or apply
Work and Hygiene Practices
cosmetics while handling the product. Wash hands
thoroughly after handling.
Keep out of reach of children. Store at controlled
Storage and Handling Practices
room temperature between 15掳 鈥? 30掳 C ( 59掳-86掳 F)
SECTION 8: EXPOSURE CONTROLS / PERSONAL PROTECTION
Use adequate ventilation when handling raw
Engineering Controls
materials
Personal Protection
No special requirements under normal conditions of
Respiratory Protection
use.
Approved eye protection to safeguard against
Eye Protection potential eye contact, irritation or injury is
recommended.
Gloves are recommended.
Hand Protection
No special requirements.
Body Protection
SECTION 9: PHYSICAL / CHEMICAL PROPERTIES
Pink round tablet bisected on one side with the
Physical state and appearance
debossed logo 鈥楶AD 0116鈥? on the same side.
NA
Molecular Weight
NA
Boiling Point
NA
Vapor Density (AIR=1)
NA
Vapor Pressure (mm Hg)
NA
Melting/Freezing Point
NA
pH
Partially soluble
Water Solubility
NA
Specific Gravity (Water =1)
NA
Water Reactivity
Paddock Laboratories, Inc. Page 4 of 6
NA
Volatility
No odor
Odor
SECTION 10: STABILITY AND REACTIVITY
Stable under labeled storage conditions.
Stability
NA
Incompatible Temperature
Oxidizing agents, bases.
Incompatible Materials
No
Hazardous Polymerization
When heated to decomposition the material emits
Hazardous Decomposition
very toxic fumes of HCl and NOx
SECTION 11: TOXICOLOGICAL INFORMATION
Oral Rat: LD50: 160 mg/kg
Oral Mouse LD50: 227 mg/kg
No
Suspected Cancer Agent
SECTION 12: ECOLOGICAL INFORMATION
NA
Environmental Stability
NA
Ecotoxicity
NA
Products of Biodegradation
NA
Special Remarks
SECTION 13: WASTE DISPOSAL
Dispose of material according to local, state, federal and environmental disposal regulations or company
operating procedures.
SECTION 14: TRANSPORTATION INFORMATION
Not hazardous
DOT classification
NA
Identification
Paddock Laboratories, Inc. Page 5 of 6
NA
DOT Label(s) Required
SECTION 15: REGULATORY INFORMATION
NA
US SARA Reporting Requirements
NA
Federal and State Regulations
Benzphetamine Hydrochloride is a 鈥渄rug鈥? as defined
U.S. TSCA Inventory Status by the Federal Food, Drug, and Cosmetic Act and is
therefore not a chemical substance under TSCA.
SECTION 16: OTHER INFORMATION
DEFINITIONS OF ABBREVATIONS USED:
American Conference of Governmental Industry Hygienists
ACGIH
Chemical Abstract Service
CAS
International Agency for Research on Cancer
IARC
Immediately Dangerous to Life or Health Level
IDLH
Medial Lethal Concentration
LC50
Medial Lethal Dose
LD50
Mine Safety and Health Administration
MSHA
Not Available
NA
No Data
ND
Not Established
NE
National Institute for Occupational Safety and Health
NIOSH
National Toxicology Program
NTP
Occupational Safety and Health Administration
OSHA
Permissible Exposure Limit
PEL
Superfund Amendments and Reauthorization Act
SARA
Short Term Exposure Limit
STEL
Threshold Limit Value
TLV
Time Weighted Average
TWA
SECTION 17: DISCLAIMER
The information contained in this Material Safety Data Sheet has been compiled from reliable sources and
is believed to be correct as of the date issued. It is the responsibility of the user to determine the
appropriateness and applicability to their situation. Paddock Laboratories, Inc. disclaims any expressed or
implied warranty as to the accuracy of the above information and shall not be held liable for any direct,
incidental, or consequential damages from use or reliance on the above information.
Paddock Laboratories, Inc. Page 6 of 6
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