B眉hlmann Laboratories AG Postadresse/Mailing address:
Baselstrasse 55 B眉hlmann Laboratories AG
CH 鈥? 4124 Sch枚nenbuch/Basel Postfach
(Switzerland) CH 鈥? 4123 Allschwil 1
Tel.: +41 (61) 487 12 12 www.buhlmannlabs.ch
Fax: +41 (61) 487 12 34 info@buhlmannlabs.ch
MATERIAL SAFETY DATA SHEET
FOR ACE colorimetric, KK-ACE
1. Identification of the Product and of the Company
Product: ACE colorimetric (Angiotensin Converting Enzyme)
In vitro diagnostic reagents for measuring the activity of angiotensin converting enzyme in human serum, urine
Purpose:
and tissue by a colorimetric method
B脺HLMANN Laboratories AG
Company:
Baselstrasse 55
CH-4124 Sch枚nenbuch, Switzerland
Email: info@buhlmannlabs.ch
Emergency phone No: +41 (0)61 487 1212 Fax No: +41 (0)61 487 1234
2. Composition and Hazardous Ingredients
B-ACE-IB, B-ACE-DB, B-ACE-SUB, B-
Kit Components:
ACE-CA, B-ACE-CON, B-ACE-CR, B-ACE-NAOH, B-ACE-PTS
Hazardous Ingredient Kit Component Concentration
Human Serum B-ACE-CON n/a
Cyanuric chloride B-ACE-CR 鈮? 98 %
Sodium Hydroxide B-ACE-NAOH < 0.1 N
3. Hazard Identification
Human Serum (or its components) used in the manufacture of components was tested and found negative for HBV, HCV and
HIV. However no known test method can offer assurance that these products will not be infectious.
Cyanuric chloride is very toxic and might cause irritations after skin contact or inhalation.
4. Emergency and First Aid Measures
It is not expected to give rise to an acute hazard under normal conditions of use.
Eye contact: Flush eyes with large amounts of water for at least 15 minutes.
Ingestion: Flush mouth with large amounts of water, make sure not to swallow rinse.
Skin: Wash well with soap and large amounts of water. If skin is injured or material gets into open wound.
If warranted, seek medical attention.
5. Fire and Explosion Hazard Data
The components are non-flammable. Use extinguishing media appropriate to surrounding fire. No special equipment or
procedures are required.
6. Accidental Release Measures
Absorb spills of reagent and patient samples with absorbent paper, taking care not to spread the material. Clean spill area with a
potent disinfectant. Discard all materials used to absorb spill and disinfect area into biohazard waste collection for proper disposal.
7. Handling and storage
Storage
Store all reagents as dedicated in the relevant instructions for use.
Handling
Adherence to the basic rules of laboratory safety should provide adequate protection:
Do not eat, drink, smoke or apply cosmetics in the laboratory.
Do not pipet solutions by mouth.
Avoid splashing or forming an aerosol.
Avoid direct contact by using protective articles such as lab coats and disposable gloves.
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MSDS: ACE colorimetric B脺HLMANN LABORATORIES AG
8. Exposure control/personal protection
Wear appropriate personal protective equipment when working with reagents or patient samples, including lab coats, disposable
gloves and eye protection. Avoid hand/mouth contact. Wash hands as soon as possible after handling reagents or patient
specimens.
9. Physical and Chemical Properties
Appearance Odor Boiling Point pH Rel. Density Solubility in Water
B-ACE-IB clear, colourless solution n/a ~100 掳C 7.1 鈥? 7.3 ~1 g/ml complete
B-ACE-DB, clear, colourless solution n/a ~100 掳C 7.1 鈥? 7.3 ~1 g/ml complete
B-ACE-SUB lyophilisate n/a n/a n/a ~1 g/ml* complete
B-ACE-CA lyophilisate n/a n/a n/a ~1 g/ml* complete
B-ACE-CON lyophilisate n/a n/a n/a ~1 g/ml* complete
B-ACE-CR white powder n/a n/a n/a 1.92 g/ml complete
B-ACE-NAOH clear, colourless solution n/a ~100 掳C > 10 ~1 g/ml* complete
* reconstituted solution
10. Stability and Reactivity
The reagents in the kit are stable under the storage conditions described in the package insert. Hazardous decomposition will not
occur.
11. Toxicological Information
Cyanuric chloride is very toxic and might cause irritations after skin contact or inhalation.
12. Ecological Information
not applicable
13. Disposal
All potential hazardous materials must be disposed of in accordance with the prevailing regulations and guidelines of the agencies
holding juristiction over the laboratory. Excess calibrators, patient samples or empty containers should be disposed according to
institutional policy for biohazardous material, such as autoclaving for at least one hour at 121.5 掳C.
14. Transportation Information
not applicable
15. Regulatory Information
CAS No. R-Phrases S-Phrases EC-Number
Cyanuric chloride 108-77-0 36/37/38 28 613-009-00-5
16. Other informations
Only trained personal should handle this product. All actions should be done in accordance with legal regulations and common
practised hygiene measures in the labs. Read the instruction for use (IFU) carefully.
The information provided in this Material Safety Data Sheet (MSDS) is believed to be accurate and represents the best
information currently available to us. However, we make no warranty or merchantability or any other warranty, expressed
or implied, with respect to such information, and we assume no liability for its use. Users should make their own
investigations to determine the suitability of the information for their particular purposes.
November 25,2003/AM
This MSDS replaces all former versions.
MSDS No.: KK-ACE/03
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