SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 09/JUN/2005
Date Updated: 13/MAR/2004
Version 1.3
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name 2-CHLOROPROPANE, 99%
Product Number C68563
Company Sigma-Aldrich Pty. Ltd.
12 Anella Avenue
Castle Hill NSW 2154
Australia
Technical Phone # +61 2 9841 0555 (1800 800 097)
Fax +61 2 9841 0500 (1800 800 096)
Emergency Phone # +44 8701906777 (1800 448 465)
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
2-CHLOROPROPANE 75-29-6 200-858-8 602-018-00-X
Formula C3H7Cl
Molecular Weight 78.54 AMU
Synonyms Chlorodimethylmethane * Isoprid *
Isopropylchloride * Narcosop * sec-Propyl
chloride * 2-Propyl chloride
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Highly flammable. Harmful by inhalation, in contact with skin and
if swallowed.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Carbon dioxide, dry chemical powder, or appropriate
foam.
Unsuitable: Carbon Dioxide, dry chemical powder, or appropriate
foam. Water can be applied as a spray or fog and if properly
applied is capable of extinguishing the fire by sweeping the
flames off the surface of the burning liquid.
SPECIAL RISKS
Specific Hazard(s): Extremely flammable. Vapor may travel
considerable distance to source of ignition and flash back.
Emits toxic fumes under fire conditions.
Explosion Hazards: Vapor may travel considerable distance to
source of ignition and flash back. Container explosion can occur
under fire conditions. In advanced or massive fires the area
should be evacuated and the fire should be fought from a remote
explosion-resistant location.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
SPECIFIC METHOD(S) OF FIRE FIGHTING
Use water spray to cool fire-exposed containers.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area. Shut off all sources of ignition. Use nonsparking
tools.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Ventilate area and wash spill site after material pickup is
complete. Cover with an activated carbon adsorbent, take up and
place in closed containers. Transport outdoors.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Avoid
contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.
STORAGE
Conditions of Storage: Keep container closed. Keep away from
heat, sparks, and open flame.
SPECIAL REQUIREMENTS: May develop pressure. Open carefully.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Use nonsparking tools. Mechanical
exhaust required.
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GENERAL HYGIENE MEASURES
Wash thoroughly after handling. Wash contaminated clothing before
reuse.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Liquid
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 35 掳C
MP/MP Range -118 掳C
Flash Point -21 掳C Method: closed cup
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits Lower: 2.4 %
Vapor Pressure 444.103 mmHg 20 掳C
SG/Density 0.86 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents, Strong bases.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Hydrogen chloride gas.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: TX4410000
ACUTE TOXICITY
LD50
Oral
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Rat
5000 mg/kg
Remarks: Autonomic Nervous System:Other (direct)
parasympathomimetic. Behavioral:Somnolence (general depressed
activity). Lungs, Thorax, or Respiration:Cyanosis.
LC50
Inhalation
Rat
120,000 mg/m3
Remarks: Blood:Changes in leukocyte (WBC) count.
Biochemical:Enzyme inhibition, induction, or change in blood or
tissue levelsTrue cholinesterase. Biochemical:Enzyme inhibition,
induction, or change in blood or tissue levels: Transaminases.
LD50
Oral
Mouse
1300 mg/kg
Remarks: Autonomic Nervous System:Other (direct)
parasympathomimetic. Behavioral:Somnolence (general depressed
activity). Lungs, Thorax, or Respiration:Cyanosis.
LC50
Inhalation
Mouse
119,000 mg/m3
SIGNS AND SYMPTOMS OF EXPOSURE
Symptoms of exposure may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea, and
vomiting. To the best of our knowledge, the chemical, physical,
and toxicological properties have not been thoroughly
investigated.
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: Harmful if absorbed through skin.
Eye Contact: Causes eye irritation.
Inhalation: Harmful if inhaled. Vapor or mist is irritating to
the mucous membranes and upper respiratory tract.
Ingestion: Harmful if swallowed.
TARGET ORGAN INFORMATION
Liver. Nerves.
CHRONIC EXPOSURE - MUTAGEN
ZPOS
Histidine reversion (Ames)
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Burn in a chemical incinerator equipped with an
afterburner and scrubber but exert extra care in igniting as this
material is highly flammable. Observe all federal, state, and
ALDRICH - C68563 www.sigma-aldrich.com Page 4
local environmental regulations.
14 - Transport Information
RID/ADR
UN#: 2356
Class: 3
PG: I
Proper Shipping Name: 2-Chloropropane
IMDG
UN#: 2356
Class: 3
PG: I
Proper Shipping Name: 2-Chloropropane
Marine Pollutant: No
Severe Marine Pollutant: No
IATA
UN#: 2356
Class: 3
PG: I
Proper Shipping Name: 2-Chloropropane
Inhalation Packing Group I: No
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 602-018-00-X
NOTA: C
INDICATION OF DANGER: F Xn
Highly Flammable. Harmful.
R-PHRASES: 11 20/21/22
Highly flammable. Harmful by inhalation, in contact with skin
and if swallowed.
S-PHRASES: 9 29
Keep container in a well-ventilated place. Do not empty into
drains.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 2 (self-classification)
SWITZERLAND
SWISS POISON CLASS: 3
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
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DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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