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MSDS Material Safety Data Sheet
CAS

646-07-1

File Name: 646-07-1.asp

                              SIGMA-ALDRICH

Material Safety Data Sheet

Date Printed: 08/JUN/2005
Date Updated: 01/JUL/2004
Version 1.2
According to 91/155/EEC

Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.

1 - Product and Company Information

Product Name 4-METHYLVALERIC ACID, 99%
Product Number 277827

Company Sigma-Aldrich Pty. Ltd.
12 Anella Avenue
Castle Hill NSW 2154
Australia
Technical Phone # +61 2 9841 0555 (1800 800 097)
Fax +61 2 9841 0500 (1800 800 096)
Emergency Phone # +44 8701906777 (1800 448 465)

2 - Composition/Information on Ingredients

Product Name CAS # EC no Annex I
Index Number
4-METHYLPENTANOIC ACID 646-07-1 211-464-0 None

Formula C6H12O2
Molecular Weight 116.16 AMU

3 - Hazards Identification

SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Harmful in contact with skin.


4 - First Aid Measures

AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.

AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.

AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.

AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.

5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.

SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.

SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.

6 - Accidental Release Measures

PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.

PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.

METHODS FOR CLEANING UP
Absorb on sand or vermiculite and place in closed containers for
disposal. Ventilate area and wash spill site after material
pickup is complete.

7 - Handling and Storage

HANDLING
Directions for Safe Handling: Do not breathe vapor. Avoid
contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.

STORAGE
Conditions of Storage: Keep tightly closed.

8 - Exposure Controls / Personal Protection

ENGINEERING CONTROLS
Use only in a chemical fume hood. Safety shower and eye bath.

GENERAL HYGIENE MEASURES
Wash thoroughly after handling.

PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.

9 - Physical and Chemical Properties

Appearance Color: Faintly brown
Form: Clear liquid

Property Value At Temperature or Pressure

pH N/A
BP/BP Range 199 - 201 掳C
MP/MP Range N/A
Flash Point 97 掳C Method: closed cup
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A


ALDRICH - 277827 www.sigma-aldrich.com Page 2
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density 0.924 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A

10 - Stability and Reactivity

STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents, Strong bases.

HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.

HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur

11 - Toxicological Information

RTECS NUMBER: NR2975000

ACUTE TOXICITY

LD50
Oral
Rat
2050 mg/kg

LD50
Skin
Rabbit
1050 UL/KG

IRRITATION DATA

Skin
Rabbit
465 mg
Remarks: Open irritation test

Eyes
Rabbit
0.93 mg
Remarks: Mild irritation effect

SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.



ALDRICH - 277827 www.sigma-aldrich.com Page 3
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: Harmful if absorbed through skin.
Eye Contact: May cause eye irritation.
Inhalation: Material may be irritating to mucous membranes and
upper respiratory tract. May be harmful if inhaled.
Ingestion: May be harmful if swallowed.

12 - Ecological Information

No data available.

13 - Disposal Considerations

SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.

14 - Transport Information

RID/ADR
UN#: 2810
Class: 6.1
PG: III
Proper Shipping Name: Toxic liquid, organic, n.o.s.

IMDG
UN#: 2810
Class: 6.1
PG: III
Proper Shipping Name: Toxic liquid, organic, n.o.s.
Marine Pollutant: No
Severe Marine Pollutant: No
Technical Name: Required

IATA
UN#: 2810
Class: 6.1
PG: III
Proper Shipping Name: Toxic liquid, organic, n.o.s.
Inhalation Packing Group I: No
Technical Name: Required

15 - Regulatory Information

CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
INDICATION OF DANGER: Xn
Harmful.
R-PHRASES: 21
Harmful in contact with skin.
S-PHRASES: 36/37
Wear suitable protective clothing and gloves.

16 - Other Information

WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our


ALDRICH - 277827 www.sigma-aldrich.com Page 4
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.

DISCLAIMER
For R&D use only. Not for drug, household or other uses.




ALDRICH - 277827 www.sigma-aldrich.com Page 5

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