SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 24/MAY/2005
Date Updated: 13/MAR/2004
Version 1.1
According to 91/155/EEC
1 - Product and Company Information
Product Name SULFANILAMIDE
Product Number S9251
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
SULFANILAMIDE 63-74-1 200-563-4 None
Formula C6H8N2O2S
Molecular Weight 172.21 AMU
Synonyms Albexan * Albosal * Ambeside *
p-Aminobenzenesulfamide *
p-Aminobenzenesulfonamide *
4-Aminobenzenesulfonamide *
p-Aminophenylsulfonamide *
4-Aminophenylsulfonamide * p-Anilinesulfonamide
* Aniline-p-sulfonic amide * Antistrept *
Astreptine * Astrocid * Bacteramid * Bactesid *
Benzenesulfonamide, p-amino- * Collomide *
Colsulanyde * Copticide * Deseptyl * Dipron *
Ergaseptine * Erysipan * Estreptocida * F 1162 *
1162 F * Fourneau 1162 * Gerison * Gombardol *
Lusil * Lysococcine * Neococcyl * Orgaseptine *
PABS * Prontalbin * Prontosil album * Prontosil
I * Prontosil White * Prontylin * Pronzin album
* Proseptal * Proseptine * Proseptol *
Pysococcine * Rubiazol A * Sanamid * Septamide
album * Septanilam * Septinal * Septolix *
Septoplex * Septoplix * Stopton album * Stramid
* Strepamide * Strepsan * Streptagol *
Streptamid * Streptasol * Streptocid album *
Streptocide White * Streptoclase * Streptocom *
Streptol * p-Sulfamidoaniline * Strepton *
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Not hazardous according to Directive 67/548/EC.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If breathing becomes difficult,
call a physician.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Exercise appropriate precautions to minimize direct contact with
skin or eyes and prevent inhalation of dust.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Avoid inhalation. Avoid contact
with eyes, skin, and clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaust required.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Wear dust mask.
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Hand Protection: Protective gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Solid
Property Value At Temperature or Pressure
pH N/A
BP/BP Range N/A
MP/MP Range 165 - 167 掳C
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density N/A
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Nitrogen oxides, Sulfur oxides.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: WO8400000
ACUTE TOXICITY
LD50
Oral
Rat
3900 mg/kg
LD50
Intravenous
Rat
1400 MG/KG
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LD50
Oral
Mouse
3000 mg/kg
LD50
Intraperitoneal
Mouse
5 MG/KG
LD50
Subcutaneous
Mouse
2900 MG/KG
LD50
Intravenous
Mouse
500 MG/KG
LD50
Oral
Dog
2000 mg/kg
LD50
Oral
Rabbit
1300 mg/kg
LD50
Oral
Guinea pig
3130 mg/kg
SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: May be harmful if inhaled. Material may be
irritating to mucous membranes and upper respiratory tract.
Ingestion: May be harmful if swallowed.
CHRONIC EXPOSURE - CARCINOGEN
Rat
Route of Application: Subcutaneous
Exposure Time: 9W
Result: Tumorigenic:Carcinogenic by RTECS criteria.
Tumorigenic:Tumors at site or application.
CHRONIC EXPOSURE - MUTAGEN
Rat
30 UMOL/L
Cell Type: liver
DNA damage
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CHRONIC EXPOSURE - TERATOGEN
Species: Woman
Dose: 974 MG/KG
Route of Application: Unreported
Exposure Time: (34-37W PREG)
Result: Specific Developmental Abnormalities: Blood and
lymphatic system (including spleen and marrow).
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Rat
Dose: 22 MG/KG
Route of Application: Oral
Exposure Time: (1-22D PREG)
Result: Effects on Newborn: Live birth index (# fetuses per
litter; measured after birth). Effects on Newborn: Viability
index (e.g., # alive at day 4 per # born alive). Effects on
Newborn: Weaning or lactation index (e.g., # alive at weaning
per # alive at day 4).
Species: Rat
Dose: 22 MG/KG
Route of Application: Oral
Exposure Time: (1-22D PREG)
Result: Effects on Newborn: Growth statistics (e.g., reduced
weight gain).
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
Non-hazardous for road transport.
IMDG
Non-hazardous for sea transport.
IATA
Non-hazardous for air transport.
15 - Regulatory Information
Not hazardous according to Directive 67/548/EC.
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
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information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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