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MSDS Material Safety Data Sheet
CAS

543-20-4

File Name: 543-20-4.asp

                              SIGMA-ALDRICH

Material Safety Data Sheet

Date Printed: 17/OCT/2005
Date Updated: 13/MAR/2004
Version 1.2
According to 91/155/EEC

Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.

1 - Product and Company Information

Product Name SUCCINYL CHLORIDE, 95%
Product Number S6452

Company Sigma-Aldrich Pty. Ltd.
12 Anella Avenue
Castle Hill NSW 2154
Australia
Technical Phone # +61 2 9841 0555 (1800 800 097)
Fax +61 2 9841 0500 (1800 800 096)
Emergency Phone # +44 8701906777 (1800 448 465)

2 - Composition/Information on Ingredients

Product Name CAS # EC no Annex I
Index Number
SUCCINYL CHLORIDE 543-20-4 208-838-0 None

Formula C4H4Cl2O2
Molecular Weight 154.98 AMU
Synonyms 1,2-Bis(chlorocarbonyl)ethane * Butanedioyl
dichloride (9CI) *
1,2-Ethanediylbis(chloroformate) * Succinic acid
dichloride * Succinic chloride * Succinoyl
chloride * Succinyl dichloride

3 - Hazards Identification

SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Reacts violently with water. Causes burns.


4 - First Aid Measures

AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.

AFTER EYE CONTACT
Assure adequate flushing of the eyes by separating the eyelids
with fingers.

AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.

5 - Fire Fighting Measures

CONDITIONS OF FLAMMABILITY
Water hydrolyzes material liberating acidic gas which in contact
with metal surfaces can generate flammable and/or explosive
hydrogen gas.

EXTINGUISHING MEDIA
Suitable: Carbon dioxide. Dry chemical powder.
Unsuitable: Do not use water.

SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.

SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.

6 - Accidental Release Measures

PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area. Shut off all sources of ignition.

PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.

METHODS FOR CLEANING UP
Cover with dry-lime, sand, or soda ash. Place in covered
containers using non-sparking tools and transport outdoors.
Ventilate area and wash spill site after material pickup is
complete.

7 - Handling and Storage

HANDLING
Directions for Safe Handling: Do not breathe vapor. Do not get
in eyes, on skin, on clothing. Avoid prolonged or repeated
exposure.

STORAGE
Conditions of Storage: Keep tightly closed. Keep away from heat
and open flame. Store in a cool dry place.
Incompatible Materials: Do not allow contact with water

8 - Exposure Controls / Personal Protection

ENGINEERING CONTROLS
Use only in a chemical fume hood. Safety shower and eye bath.

GENERAL HYGIENE MEASURES
Wash thoroughly after handling. Remove and wash contaminated
clothing promptly.

PERSONAL PROTECTIVE EQUIPMENT
Special Protective Measures: Wear appropriate government approved
respirator, chemical-resistant gloves, safety goggles, other
protective clothing. Faceshield (8-inch minimum).

9 - Physical and Chemical Properties

Appearance Color: Very deep yellow-green
Form: Clear liquid

Property Value At Temperature or Pressure


ALDRICH - S6452 www.sigma-aldrich.com Page 2
pH N/A
BP/BP Range 95.0 - 96.0 掳C 16 mmHg
MP/MP Range 15 掳C
Flash Point 76 掳C Method: closed cup
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density 1.376 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A

10 - Stability and Reactivity

STABILITY
Materials to Avoid: Strong bases, Oxidizing agents, Alcohols,
Water.

HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Phosgene gas, Hydrogen chloride
gas Carbon monoxide, Carbon dioxide.

11 - Toxicological Information

RTECS NUMBER: WN4900000

SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
Symptoms of exposure may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea, and
vomiting. Inhalation may result in spasm, inflammation and edema
of the larynxand bronchi, chemical pneumonitis, and pulmonary
edema. Material is extremely destructive to tissue of the mucous
membranes and upper respiratory tract, eyes, and skin.

ROUTE OF EXPOSURE
Multiple Routes: Harmful if swallowed, inhaled, or absorbed
through skin. Causes burns.

12 - Ecological Information

No data available.

13 - Disposal Considerations

SUBSTANCE DISPOSAL
The material should be ignited in the presence of sodium carbonate


ALDRICH - S6452 www.sigma-aldrich.com Page 3
and slaked lime (calcium hydroxide). The substance should be mixed
with vermiculite and then with the dry caustics, wrapped in paper
and burned in a chemical incinerator equipped with an afterburner
and scrubber. Observe all federal, state, and local environmental
regulations.

14 - Transport Information

RID/ADR
UN#: 3265
Class: 8
PG: II
Proper Shipping Name: Corrosive liquid, acidic,
organic, n.o.s.

IMDG
UN#: 3265
Class: 8
PG: II
Proper Shipping Name: CORROSIVE LIQUID, ACIDIC,
ORGANIC, N.O.S.
Marine Pollutant: No
Severe Marine Pollutant: No
Technical Name: Required

IATA
UN#: 3265
Class: 8
PG: II
Proper Shipping Name: Corrosive liquid, acidic,
organic, n.o.s.
Inhalation Packing Group I: No
Technical Name: Required

15 - Regulatory Information

CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
INDICATION OF DANGER: C
Corrosive.
R-PHRASES: 14-34
Reacts violently with water. Causes burns.
S-PHRASES: 26-36/37/39-45
In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice. Wear suitable protective
clothing, gloves, and eye/face protection. In case of accident
or if you feel unwell, seek medical advice immediately (show
the label where possible).

SWITZERLAND
SWISS POISON CLASS: 3

16 - Other Information

WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice


ALDRICH - S6452 www.sigma-aldrich.com Page 4
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.

DISCLAIMER
For R&D use only. Not for drug, household or other uses.




ALDRICH - S6452 www.sigma-aldrich.com Page 5

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