SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 07/DEC/2005
Date Updated: 27/MAY/2005
Version 1.3
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name CYANAMIDE, 99%
Product Number 187364
Company Sigma-Aldrich Pty. Ltd.
12 Anella Avenue
Castle Hill NSW 2154
Australia
Technical Phone # +61 2 9841 0555 (1800 800 097)
Fax +61 2 9841 0500 (1800 800 096)
Emergency Phone # +44 8701906777 (1800 448 465)
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
CYANAMIDE 420-04-2 206-992-3 615-013-00-2
Formula CH2N2
Molecular Weight 42.04 AMU
Synonyms Alzogur * Amidocyanogen * Carbamonitrile *
Carbimide * Carbodiimide * Cyanamide (ACGIH) *
Cyanoamine * N-Cyanoamine * Cyanogenamide *
Cyanogen nitride * Hydrogen cyanamide * TsAKS *
USAF EK-1995
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Harmful in contact with skin. Toxic if swallowed. Irritating to
eyes and skin. May cause sensitization by skin contact.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Carbon dioxide, dry chemical powder, or appropriate
foam.
Unsuitable: Do not use water.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
Explosion Hazards: Container explosion may occur under fire
conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
SPECIFIC METHOD(S) OF FIRE FIGHTING
Use water spray to cool fire-exposed containers.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe dust. Do not get in
eyes, on skin, on clothing. Avoid prolonged or repeated exposure.
STORAGE
Conditions of Storage: Keep tightly closed.
Store at 2-8掳C
SPECIAL REQUIREMENTS: Moisture sensitive. Avoid contact with
bases.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Use only in a chemical fume hood.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Wash thoroughly after
handling.
EXPOSURE LIMITS
Country Source Type Value
Poland NDS 2 MG/M3
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Poland NDSCh 4 MG/M3
Poland NDSP -
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 2 mg/m3
EXPOSURE LIMITS - GERMANY
Source Type Value
TRGS 900 OEL 2 mg/m3, E
Remarks: H
EXPOSURE LIMITS - NORWAY
Source Type Value
OEL 2 mg/m3
EXPOSURE LIMITS - SWITZERLAND
Source Type Value
OEL OEL 2 mg/m3
Remarks: E
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL OEL 2 mg/m3
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Color: White
Form: Crystals
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 83 掳C 0.5 mmHg
MP/MP Range 44 掳C
Flash Point 141 掳C Method: closed cup
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure 0.00375 mmHg 20 掳C
SG/Density 1.282 g/cm3 20 掳C
Partition Coefficient N/A
Viscosity N/A
Vapor Density 1.45 g/l
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content <2%
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility Solubility in Water:Soluble.
Other Solvents: ETHER, AMINES, KETONES
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10 - Stability and Reactivity
STABILITY
Stable: Unstable.
Conditions of Instability: Heat sensitive.
Conditions to Avoid: Moisture. Contact with acids liberates very
toxic gas.
Materials to Avoid: Strong oxidizing agents, Strong reducing
agents, Bases, Acids Iron and iron salts., Steel, Brass, Lead
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide,
and nitrogen oxides.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: May occur
11 - Toxicological Information
RTECS NUMBER: GS5950000
ACUTE TOXICITY
LD50
Oral
Rat
125 mg/kg
LD50
Skin
Rat
84 mg/kg
LD50
Intravenous
Rat
56 MG/KG
LD50
Oral
Mouse
388 mg/kg
LD50
Intraperitoneal
Mouse
200 MG/KG
LD50
Oral
Cat
100 mg/kg
LD50
Oral
Rabbit
150 mg/kg
LD50
Skin
Rabbit
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590 mg/kg
SENSITIZATION
Skin: May cause allergic skin reaction.
SIGNS AND SYMPTOMS OF EXPOSURE
Causes severe corneal edema. Temporary blindness has been
reported. Symptoms may be delayed. Exposure can cause: Headache.
Dizziness. Hypotension. Salivation. Ataxia. To the best of our
knowledge, the chemical, physical, and toxicological properties
have not been thoroughly investigated. Exposure to and/or
consumption of alcohol may increase toxic effects.
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: Toxic if absorbed through skin.
Eye Contact: Causes eye irritation.
Inhalation: Material is irritating to mucous membranes and upper
respiratory tract. May be harmful if inhaled.
Ingestion: Toxic if swallowed.
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Rat
Dose: 2450 MG/KG
Route of Application: Oral
Exposure Time: (70D MALE/2W PRE-2W PREG)
Result: Effects on Fertility: Pre-implantation mortality (e.g.,
reduction in number of implants per female; total number of
implants per corpora lutea). Effects on Fertility: Other
measures of fertility
Species: Rat
Dose: 1750 MG/KG
Route of Application: Oral
Exposure Time: (70D MALE)
Result: Paternal Effects: Testes, epididymis, sperm duct.
Paternal Effects: Prostate, seminal vessicle, Cowper's gland,
accessory glands. Effects on Fertility: Male fertility index
(e.g., # males impregnating females per # males exposed to
fertile nonpregnant females).
Species: Rat
Dose: 2600 MG/KG
Route of Application: Oral
Exposure Time: (70D MALE/2W PRE-3W PREG)
Result: Effects on Newborn: Live birth index (# fetuses per
litter; measured after birth). Effects on Newborn: Growth
statistics (e.g., reduced weight gain). Effects on Newborn:
Delayed effects.
Species: Rat
Dose: 208 MG/KG
Route of Application: Oral
Exposure Time: (70D MALE/2W PRE-3W PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
Effects on Newborn: Live birth index (# fetuses per litter;
measured after birth).
12 - Ecological Information
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N/A
ECOTOXICOLOGICAL EFFECTS
Test Type: LC50 Fish
Species: Cyprinodon variegatus (Sheepshead minnow)
Time: 96 h
Value: 58 mg/l
Test Type: LC50 Fish
Species: Lepomis macrochirus (Bluegill)
Time: 96 h
Value: 88 mg/l
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
UN#: 2811
Class: 6.1
PG: III
Proper Shipping Name: Toxic solid, organic, n.o.s.
IMDG
UN#: 2811
Class: 6.1
PG: III
Proper Shipping Name: Toxic solid, organic, n.o.s.
Marine Pollutant: No
Severe Marine Pollutant: No
Technical Name: Required
IATA
UN#: 2811
Class: 6.1
PG: III
Proper Shipping Name: Toxic solid, organic, n.o.s.
Inhalation Packing Group I: No
Technical Name: Required
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 615-013-00-2
INDICATION OF DANGER: T
Toxic.
R-PHRASES: 21-25-36/38-43
Harmful in contact with skin. Toxic if swallowed. Irritating to
eyes and skin. May cause sensitization by skin contact.
S-PHRASES: 3-22-36/37-45
Keep in a cool place. Do not breathe dust. Wear suitable
protective clothing and gloves. In case of accident or if you
feel unwell, seek medical advice immediately (show the label
where possible).
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COUNTRY SPECIFIC INFORMATION
Germany
WGK: 2
SWITZERLAND
SWISS POISON CLASS: 3
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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