SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 11/JUL/2005
Date Updated: 14/MAR/2004
Version 1.3
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name CROTONALDEHYDE( (CIS+TRANS), STAB.
Product Number 27980
Company Sigma-Aldrich Pty. Ltd.
12 Anella Avenue
Castle Hill NSW 2154
Australia
Technical Phone # +61 2 9841 0555 (1800 800 097)
Fax +61 2 9841 0500 (1800 800 096)
Emergency Phone # +44 8701906777 (1800 448 465)
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
CROTONALDEHYDE (CIS+TRANS) 4170-30-3 224-030-0 605-009-00-9
Formula C4H6O
Molecular Weight 70.09 AMU
Synonyms 2-Butenal (9CI) * 2-Butenaldehyde * Crotonal *
Crotonaldehyde (ACGIH:OSHA) * Crotonic aldehyde
* 1-Formylpropene * Krotonaldehyd (Czech) *
beta-Methylacrolein * Methylpropenal * RCRA
waste number U053
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Highly flammable. Toxic in contact with skin and if swallowed.
Very toxic by inhalation. Irritating to respiratory system and
skin. Risk of serious damage to eyes. Harmful: danger of serious
damage to health by prolonged exposure if swallowed. Very toxic to
aquatic organisms. Possible risk of irreversible effects.
Muta. Cat.3
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Flammable liquid. Emits toxic fumes under
fire conditions.
Explosion Hazards: Vapor may travel considerable distance to
source of ignition and flash back. Container explosion may occur
under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area. Shut off all sources of ignition.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Cover with dry-lime, sand, or soda ash. Place in covered
containers using non-sparking tools and transport outdoors.
Ventilate area and wash spill site after material pickup is
complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Do not get
in eyes, on skin, on clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed. Keep away from heat,
sparks, and open flame.
Store at 2-8掳C
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Use nonsparking tools. Use only in a
chemical fume hood.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Wash thoroughly after
handling.
FLUKA - 27980 www.sigma-aldrich.com Page 2
EXPOSURE LIMITS
Country Source Type Value
Poland NDS 6 MG/M3
Poland NDSCh 12 MG/M3
Poland NDSP -
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 6 mg/m3
2 ppm
Remarks: H
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL LTEL 6 mg/m3
2 ppm
OEL STEL 18 mg/m3
6 ppm
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Liquid
Color: Almost colorless
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 101 - 102 掳C
MP/MP Range N/A
Flash Point 13 掳C Method: closed cup
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density 0.852 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Conditions to Avoid: Heat.
Materials to Avoid: Reducing agents, Bases, Oxidizing agents.
FLUKA - 27980 www.sigma-aldrich.com Page 3
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: GP9499000
ACUTE TOXICITY
LD50
Oral
Rat
80 mg/kg
Remarks: Cardiac:Pulse rate increased without fall it BP. Lungs,
Thorax, or Respiration:Cyanosis. Nutritional and Gross
Metabolic:Changes in:Body temperature decrease.
LC50
Inhalation
Rat
200 mg/m3
2H
LD50
Oral
Mouse
104 mg/kg
LC50
Inhalation
Mouse
580 mg/m3
2H
LD50
Skin
Rabbit
380 UL/KG
LD50
Skin
Guinea pig
30 UL/KG
SIGNS AND SYMPTOMS OF EXPOSURE
Material is extremely destructive to tissue of the mucous
membranes and upper respiratory tract, eyes, and skin.
Inhalation may result in spasm, inflammation and edema of the
larynxand bronchi, chemical pneumonitis, and pulmonary edema.
Symptoms of exposure may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea, and
vomiting.
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: Toxic if absorbed through skin. Readily
absorbed through skin.
Eye Contact: Causes severe eye irritation. Lachrymator.
FLUKA - 27980 www.sigma-aldrich.com Page 4
Inhalation: May be fatal if inhaled. Material is irritating to
mucous membranes and upper respiratory tract.
Ingestion: Toxic if swallowed.
CHRONIC EXPOSURE - CARCINOGEN
Result: This product is or contains a component that is not
classifiable as to its carcinogenicity based on its IARC, ACGIH,
NTP, or EPA classification.
Rat
Route of Application: Oral
Exposure Time: 2Y
Result: Tumorigenic:Carcinogenic by RTECS criteria. Liver:Tumors.
IARC CARCINOGEN LIST
Rating: Group 3
CHRONIC EXPOSURE - MUTAGEN
Result: Laboratory experiments have shown mutagenic effects.
Human
100 UMOL/L
Cell Type: fibroblast
DNA
Hamster
1600 UG/L
Cell Type: ovary
Cytogenetic analysis
Hamster
500 UG/L
Cell Type: ovary
Sister chromatid exchange
Mammal
21500 MG/L
16H
Cell Type: lymphocyte
DNA
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Burn in a chemical incinerator equipped with an
afterburner and scrubber but exert extra care in igniting as this
material is highly flammable. Observe all federal, state, and
local environmental regulations.
14 - Transport Information
RID/ADR
UN#: 1143
Class: 6.1
PG: I
Proper Shipping Name: Crotonaldehyde, stabilized
FLUKA - 27980 www.sigma-aldrich.com Page 5
IMDG
UN#: 1143
Class: 6.1
PG: I
Subrisk: 3
Proper Shipping Name: Crotonaldehyde, stabilized
Marine Pollutant: Yes
Severe Marine Pollutant: No
IATA
UN#: 1143
Class: 6.1
PG: I
Subrisk: 3
Proper Shipping Name: Crotonaldehyde, stabilized
Inhalation Packing Group I: Yes
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 605-009-00-9
INDICATION OF DANGER: F T+ N
Highly Flammable. Very toxic. Dangerous for the environment.
R-PHRASES: 11 24/25 26 37/38 41 48/22 50 68
Highly flammable. Toxic in contact with skin and if swallowed.
Very toxic by inhalation. Irritating to respiratory system and
skin. Risk of serious damage to eyes. Harmful: danger of
serious damage to health by prolonged exposure if swallowed.
Very toxic to aquatic organisms. Possible risk of irreversible
effects.
S-PHRASES: 26 28 36/37/39 45 61
In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice. After contact with skin, wash
immediately with plenty of water. Wear suitable protective
clothing, gloves, and eye/face protection. In case of accident
or if you feel unwell, seek medical advice immediately (show
the label where possible). Avoid release to the environment.
Refer to special instructions/safety data sheets.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 3
SWITZERLAND
SWISS POISON CLASS: 2
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
FLUKA - 27980 www.sigma-aldrich.com Page 6
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
FLUKA - 27980 www.sigma-aldrich.com Page 7
|