SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 31/MAY/2005
Date Updated: 12/MAR/2004
Version 1.3
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name BENZENETHIOL, 99+%
Product Number 240249
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
BENZENETHIOL 108-98-5 203-635-3 None
Formula C6H6S
Molecular Weight 110.18 AMU
Synonyms Mercaptobenzene * Phenol, thio- * Phenyl
mercaptan (ACGIH:OSHA) * RCRA waste number P014
* Thiofenol (Czech) * Thiophenol * USAF XR-19
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Flammable. Toxic in contact with skin and if swallowed. Very toxic
by inhalation. Risk of serious damage to eyes.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Combustible liquid. Emits toxic fumes under
fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Do not get
in eyes, on skin, on clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed. Keep away from heat
and open flame. Store under nitrogen.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Use only in a chemical fume hood.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Wash thoroughly after
handling.
EXPOSURE LIMITS
Country Source Type Value
Poland NDS 2 mg/m3
Poland NDSCh -
Poland NDSP
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 2.3 mg/m3
0.5 ppm
EXPOSURE LIMITS - GERMANY
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Source Type Value
TRGS 900 OEL 2 mg/m3
Remarks: NL
EXPOSURE LIMITS - NORWAY
Source Type Value
OEL 2 mg/m3
0.5 ppm
EXPOSURE LIMITS - SWITZERLAND
Source Type Value
OEL OEL 2.3 mg/m3
0.5 ppm
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL OEL 2.3 mg/m3
0.5 ppm
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Clear liquid
Color: Almost colorless
Odor: Stench.
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 169 掳C
MP/MP Range -15 掳C
Flash Point 50 掳C Method: closed cup
Flammability N/A
Autoignition Temp 450 掳C
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure 1.4 mmHg 20 掳C
SG/Density 1.078 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density 3.8 g/l
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Conditions to Avoid: Air.
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Materials to Avoid: Avoid contact with acid., Strong bases, Strong
oxidizing agents
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Sulfur oxides, Hydrogen sulfide gas.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: DC0525000
ACUTE TOXICITY
LD50
Oral
Rat
46.2 mg/kg
Remarks: Behavioral:Somnolence (general depressed activity).
Behavioral:Coma. Lungs, Thorax, or Respiration:Respiratory
depression.
LC50
Inhalation
Rat
33 ppm
4H
Remarks: Lungs, Thorax, or Respiration:Respiratory stimulation.
Behavioral:Somnolence (general depressed activity). Sense Organs
and Special Senses (Nose, Eye, Ear, and Taste):Eye:Lacrimation.
LD50
Skin
Rat
300 mg/kg
Remarks: Behavioral:Tremor. Lungs, Thorax, or
Respiration:Respiratory depression. Skin and Appendages:Skin:
After topical exposure:Primary irritation.
LD50
Intraperitoneal
Rat
9800 UG/KG
Remarks: Behavioral:Somnolence (general depressed activity).
Behavioral:Coma. Lungs, Thorax, or Respiration:Respiratory
depression.
LD50
Oral
Mouse
267 mg/kg
Remarks: Behavioral:Ataxia. Lungs, Thorax, or
Respiration:Dyspnea. Gastrointestinal:Hypermotility, diarrhea.
LC50
Inhalation
Mouse
28 ppm
4H
Remarks: Lungs, Thorax, or Respiration:Respiratory stimulation.
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Behavioral:Somnolence (general depressed activity). Sense Organs
and Special Senses (Nose, Eye, Ear, and Taste):Eye:Lacrimation.
LD50
Intraperitoneal
Mouse
25 MG/KG
LD50
Skin
Rabbit
134 mg/kg
Remarks: Behavioral:Muscle weakness. Behavioral:Ataxia. Lungs,
Thorax, or Respiration:Cyanosis.
LD50
Oral
Bird (wild)
24 mg/kg
IRRITATION DATA
Eyes
Rabbit
108 mg
Remarks: Severe irritation effect
SIGNS AND SYMPTOMS OF EXPOSURE
Symptoms of exposure may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea, and
vomiting.
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: Readily absorbed through skin. Toxic if
absorbed through skin.
Eye Contact: Severe eye irritant.
Inhalation: May be fatal if inhaled. Material may be irritating
to mucous membranes and upper respiratory tract.
Ingestion: Toxic if swallowed.
TARGET ORGAN INFORMATION
Central nervous system. Liver. Kidneys. Adrenal medulla.
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Rat
Dose: 500 MG/KG
Route of Application: Oral
Exposure Time: (6-15D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
Effects on Fertility: Litter size (e.g.; # fetuses per litter;
measured before birth). Effects on Embryo or Fetus: Other
effects to embryo.
Species: Rat
Dose: 500 MG/KG
Route of Application: Oral
Exposure Time: (6-15D PREG)
Result: Maternal Effects: Other effects.
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12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
UN#: 2337
Class: 6.1
PG: I
Proper Shipping Name: Phenyl mercaptan
IMDG
UN#: 2337
Class: 6.1
PG: I
Subrisk: 3
Proper Shipping Name: Phenyl mercaptan
Marine Pollutant: No
Severe Marine Pollutant: No
IATA
UN#: 2337
Class: 6.1
PG: I
Subrisk: 3
Proper Shipping Name: Phenyl mercaptan
Inhalation Packing Group I: No
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
INDICATION OF DANGER: T+
Very toxic.
R-PHRASES: 10 24/25 26 41
Flammable. Toxic in contact with skin and if swallowed. Very
toxic by inhalation. Risk of serious damage to eyes.
S-PHRASES: 23 26 28 36/37/39 45
Do not breathe vapor. In case of contact with eyes, rinse
immediately with plenty of water and seek medical advice. After
contact with skin, wash immediately with plenty of polyethylene
glycol. Wear suitable protective clothing, gloves, and eye/face
protection. In case of accident or if you feel unwell, seek
medical advice immediately (show the label where possible).
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 3
SWITZERLAND
SWISS POISON CLASS: 2
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16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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