SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 31/MAY/2005
Date Updated: 13/MAR/2004
Version 1.1
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name THALLIUM(I) NITRATE, 99.999%
Product Number 204609
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
THALLIUM(I) NITRATE 10102-45-1 233-273-1 None
Formula TlNO3
Molecular Weight 266.38 AMU
Synonyms Nitric acid, thallium(1+) salt * RCRA waste
number U217 * Thallium mononitrate * Thallous
nitrate
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Very toxic by inhalation and if swallowed. Danger of cumulative
effects. Toxic to aquatic organisms, may cause long-term adverse
effects in the aquatic environment.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
GENERAL INFORMATION
For thallium antidote, see Eur. J. Pharmacol., 6, 340 (1969).
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray.
SPECIAL RISKS
Specific Hazard(s): Contact with other material may cause fire.
Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves. Wear disposable coveralls and discard them after
use.
METHODS FOR CLEANING UP
Cover with dry lime or soda ash, pick up, keep in a closed
container, and hold for waste disposal. Ventilate area and wash
spill site after material pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe dust. Do not get in
eyes, on skin, on clothing.
STORAGE
Conditions of Storage: Keep tightly closed. Keep away from
combustible materials, heat, sparks, and open flame. Store in a
cool dry place.
SPECIAL REQUIREMENTS: Hygroscopic.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Use only in a chemical fume hood. Safety shower and eye bath.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling. Wash contaminated clothing before
reuse.
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 0.1 mg/m3
Remarks: SKIN
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL TWA 0.1MG(SE)/M3
PERSONAL PROTECTIVE EQUIPMENT
Special Protective Measures: Wear appropriate government approved
respirator, chemical-resistant gloves, safety goggles, other
protective clothing.
9 - Physical and Chemical Properties
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Appearance Form: Powder
Property Value At Temperature or Pressure
pH N/A
BP/BP Range N/A
MP/MP Range 206 掳C
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density N/A
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Materials to Avoid: Strong reducing agents, Strong acids.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Nitrogen oxides, Thallium.
11 - Toxicological Information
RTECS NUMBER: XG5950000
ACUTE TOXICITY
LD50
Intraperitoneal
Rat
21 UG/KG
LD50
Subcutaneous
Rat
26 MG/KG
Remarks: Brain and Coverings:Encephalitis.
Gastrointestinal:Other changes. Skin and Appendages: Other: Hair.
LD50
Oral
Mouse
15 mg/kg
LD50
Intraperitoneal
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Mouse
37293 UG/KG
SIGNS AND SYMPTOMS OF EXPOSURE
The most characteristic symptom of thallium exposure is alopecia
(loss of hair). Cutaneous effects may include dry, scaly skin
and impairment of nail growth often resulting in the appearance
of crescent-shaped strips across fingernails and toenails (Mees'
line). Other symptoms in acute poisoning relate chiefly to the
gastrointestinal tract, nervous system, skin, eyes, and
cardiovascular system. Acute poisoning results in swelling of
the feet and legs, arthralgia, vomiting, insomnia, hyperesthesia
and paresthesia of the hands and feet, mental confusion,
polyneuritis with severe pain in the legs and loins, partial
paralysis of the legs, angina-like pains, nephritis, wasting and
weakness, and lymphocytosis and eosinophilia. In chronic
poisoning, central and peripheral nervous system abnormalities
may persist including ataxia, tremor, incoordination, paralysis
of extremities, endocrine disorders, memory loss, and psychoses
may develop. To the best of our knowledge, the chemical,
physical, and toxicological properties have not been thoroughly
investigated.
ROUTE OF EXPOSURE
Eye Contact: Can cause blindness.
Inhalation: Material is irritating to mucous membranes and upper
respiratory tract.
Multiple Routes: May be fatal if inhaled, swallowed, or absorbed
through skin. Causes eye and skin irritation.
TARGET ORGAN INFORMATION
Nerves. Cardiovascular system. Eyes. Skin. Liver. Kidneys. Male
reproductive system.
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
UN#: 2727
Class: 6.1
PG: II
Proper Shipping Name: Thallium nitrate
IMDG
UN#: 2727
Class: 6.1
PG: II
Subrisk: 5.1
Proper Shipping Name: Thallium nitrate
Marine Pollutant: Yes
Severe Marine Pollutant: No
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IATA
UN#: 2727
Class: 6.1
PG: II
Subrisk: 5.1
Proper Shipping Name: Thallium nitrate
Inhalation Packing Group I: No
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
INDICATION OF DANGER: T+ N
Very toxic. Dangerous for the environment.
R-PHRASES: 26/28 33 51/53
Very toxic by inhalation and if swallowed. Danger of cumulative
effects. Toxic to aquatic organisms, may cause long-term
adverse effects in the aquatic environment.
S-PHRASES: 13 28 45 61
Keep away from food, drink, and animal feedingstuffs. After
contact with skin, wash immediately with plenty of water. In
case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible). Avoid release to
the environment. Refer to special instructions/safety data
sheets.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 2
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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