MATERIAL SAFETY DATA SHEET ARGININE
PRODUCT CODE NUMBER(S): 1930-5
PRODUCT IDENTIFICATION FIRE AND EXPLOSION DATA
Chemical Name and Synonyms: Arginine; Flammability: May be combustible if strongly heated. As
L-2-Amino-5-guanidinopentanoic acid; Guanidine with most organic compounds, fine dust dispersed in air in
aminovaleric acid the presence of an ignition source is a potential dust explo-
sion hazard.
Chemical Family: Amino acids
Extinguishing Media: Use extinguishing media appropri-
Chemical Formula: C6H14N4O2
ate to the surrounding fire. Water in flooding amounts can
Product Use: Laboratory reagent be used to cool containers, prevent dust formation, flush
Manufacturer's Name and Address: chemcial away from fire. Fight fire from upwind direction,
Caledon Laboratories Ltd. from a safe distance. Firefighters should wear protective
equipment and clothing sufficient to prevent inhalation of
40 Armstrong Avenue
dust or fumes and contact with skin and eyes.
Georgetown, Ontario L7G 4R9
Flash Point (Method Used): Not applicable
Telephone No: (905) 877-0101
Autoignition Temperature: Not applicable
Fax No: (905) 877-6666
Upper Flammable Limit (% by volume): Not applicable
Emergency Telephone No: CANUTEC (613) 996-6666
Lower Flammable Limit (% by volume): Not applicable
HAZARDOUS INGREDIENTS OF MATERIALS Hazardous Combustion Products: COx, NOx, toxic cya-
nide fumes
Ingredients % TLV Units CAS No. Sensitivity to Impact: None identified
Sensitivity to Static discharge: As with most organic pow-
Arginine >97 Not established 74-79--3
ders, mixtures of dust with air may be sensitive under
PHYSICAL DATA certain conditions, when ignited by an electrostatic or other
high-voltage spark, or other ignition source.
Physical State: Solid
TOXICOLOGICAL PROPERTIES AND HEALTH DATA
Odour and Appearance: White powder, odourless
Odour Threshold (ppm): Not applicable To the best of our knowledge, the physical, chemical and
Vapour Pressure (mm Hg): Negligible toxicological properties of this substance have not yet been
thoroughly investigated. An essential amino acid for rats.
Vapour Density (Air = 1): Not applicable
Occurs widely in animal and plant proteins. Used as a di-
Evaporation Rate: Negligible
etary supplement.
Boiling Point (degrees C): Not available
Melting Point (degrees C): 230癈 (decomposes) Toxicological Data:
pH: 10.5 to 12 (10% aqueous solution)
LD50: Not available
Specific Gravity: 1.3
LC50: Not available
Coefficient of Water/Oil distribution: Not available
Effects of Acute Exposure to Product:
SHIPPING DESCRIPTION
Inhaled: May be irritating. May cause coughing, shortness
UN: Not regulated of breath. Inhalation of large amounts may be harmful.
T.D.G. Class: Not regulated In contact with skin: Concentrated solutions may be irritat-
Pkg. Group: Not regulated ing. Dust may cause irritation. Probably not absorbed
through skin.
REACTIVITY DATA In contact with eyes: Concentrated solutions may be irri-
tating to eye tissue. Dust may cause irritation.
Chemical Stability: Stable under normal conditions of use
Ingested: Low in oral toxicity. Large doses may be irritat-
and storage. sensitive to light and moisture.
ing, causing nausea and vomiting.
Incompatibility with other substances: May react vio-
lently with strong oxidizers. Effects of Chronic Exposure to Product:
Reactivity: Avoid excessive heat, ignition sources, expo-
Carcinogenicity: Probably not carcinogenic
sure to light and moisture. generation of dust, all
incompatible materials. Teratogenicity: No human or animal information available.
Not expected to be teratogenic.
Hazardous Decomposition Products: NOx, hydrogen cy-
anide, COx Reproductive Effects: No human or animal iinformation
available. Not expected to be a reproductive hazard.
Mutagenicity: No human or in vivo information available
ARGININE
MSDS
CODE: 1930-5
REFERENCES USED
Synergistic Products: None known
CCINFO disc
PREVENTIVE MEASURES
Sax, Lewis: Hawley's Condensed Chemical Dictionary, 11th
Engineering Controls: Local exhaust ventilation recom- ed., 1987
mended.
Sax: Dangerous Properties of Industrial Materials, 5th ed.,
Respiratory Protection: Dust/mist mask. Use in chemical
.
1979
fumehood. For conditions where dust or mist is present, to
Suppliers' Material Safety Data Sheets
the maximum use specified by the respirator supplier,
NIOSH/OSHA approved half- face high-efficiency dust/mist
ADDITIONAL INFORMATION
filter respirator, or NIOSH/OSHA approved full face-piece
high-efficiency dust/mist filter respirator. Higher or unknown
Date Issued: July 7, 1999
concentrations, or for fire or spill conditions, self-contained
Revision: June 2008
breathing apparatus, or full face-piece, positive-pressure
supplied-air respirator. MSDS: 1930-5
Eye Protection: Chemical safety glasses. Do not wear Proposed Whmis Designation: Not controlled. Not re-
contact lenses when working with chemicals. quired to be updated every three years (WHMIS 1992, B-40,
Skin Protection: Wear rubber or plastic gloves and other Section 29,2)
protective clothing sufficient to limit contact.
Other Personal Protective Equipment: Safety shower Prepared by: Caledon Laboratories Ltd. (905) 877-0101
and eye-wash fountain in work area. Caledon Laboratories Ltd. believes the information contained
Leak and Spill Procedure: Ventilate area. Eliminate all herein is reliable and accurate. Caledon makes no warranty
sources of igntion. Cleanup personnel should be trained in with respect thereto and expressly disclaims all liability for reli-
the handling of chemicals, and should wear protective ance thereon. Such information is solely for your consider-
equipment and clothing sufficient to prevent inhalation of ation, investigation, and verification.
dust or fumes, and contact with skin and eyes. Wet spilled
material to prevent generation of dust. Prevent from enter-
ing sewers or waterways. Mix with inert material and place
in suitable, labelled container for disposal. Flush area of
spill thoroughly with plenty of water.
Waste Disposal: Follow all federal, provincial and local
regulations for disposal.
Handling Procedures and Equipment: COMBUSTIBLE
DUST. Workers using this chemical must be properly
trained in its hazards and its safe use, and must wear appro-
priate protective equipment and clothing. Avoid generating
dust. If there is dust, keep away from heat, sparks, and all
sources of ignition; avoid the accumulation of static charge,
use anti-sparking tools and ground and bond equipment and
containers. Use the smallest amount possible for the pur-
pose, in a designated area with adequate ventilation. Use
good housekeeping to prevent accumulations of dust. Avoid
contact with skin and eyes. Avoid inhalation. Wash thor-
oughly after handling.
Storage Requirements: Store in suitable, labelled contain-
ers, in a cool, dry, well ventilated area, away fromall ignition
sources and incompatible materials. Keep containers tightly
closed when not in use and when empty. Protect from dam-
age.
FIRST AID MEASURES
Specific Measures:
Eyes: Flush eyes thoroughly with gently running water,
holding eyelids open while flushing, for five to ten (5-10)
minutes, or until no trace of chemical remains. Get medical
advice if irritation develops.
Skin: Remove contaminated clothing. Brush or wipe off dry
material. Flush skin with plenty of running water until no evi-
dence of chemical remains. If irritation develops get medical
attention.
Inhalation: Remove to fresh air. Give oxygen and get
medical attention for any breathing difficulty.
Ingestion: If victim is alert and NOT convulsing, rinse
mouth, give several glasses of water to drink to dilute. If dis-
comfort occurs, or if a large amount has been ingested, get
medical attention.
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