Page : 1
SAFETY DATA SHEET Revised edition no : 1
Date : 16 / 12 / 2009
Supersedes : 0 / 0 / 0
Hepes, Cell Culture tested P5455
1 IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND OF THE COMPANY/UNDERTAKING
:
Powder.
Identification of the product
:
Hepes, Cell Culture tested
Trade name
:
Biotechnological industry.
Use
:
BIOWEST
Company identification
Rue de la Caille
FR-49340 NUAILLE FRANCE
Tel : +33 2 41 46 42 42
Name and function of the responsible : H閘鑞e Royer - Resposable Qualit?- email : h.royer@biowest.net
person
: ORFILA (0)1 45 42 59 59
Emergency phone nr
2 HAZARDS IDENTIFICATION
: Irritating to eyes, respiratory system and skin.
Risk Phrases
: Inhalation of dust.
Primary route of exposure
Symptoms relating to use
: May cause irritation to the respiratory tract and to other mucous membranes.
- Inhalation
Cough. Shortness of breath.
: Redness.
- Skin contact
: Pain. Redness. Tears.
- Eye contact
: No significant signs or symptoms indicative of any adverse health hazard are
- Ingestion
expected to occur as a result of ingestion. Must not come into contact with food or
be consumed.
3 COMPOSITION/INFORMATION ON INGREDIENTS
: This product is hazardous.
Components
Substance name Contents CAS No EC No Annex No Classification
Xi; R36/37/38
7365-45-9 230-907-9 ----- -----
Hepes Free acid :
4 FIRST AID MEASURES
: Assure fresh air breathing. If you feel unwell, seek medical advice.
- Inhalation
: After contact with skin, wash immediately with plenty of water.
- Skin contact
: In case of contact with eyes, rinse immediately with plenty of water and seek
- Eye contact
medical advice.
: Rinse mouth.
- Ingestion
Give water to drink if victim completely conscious/alert. Seek medical attention if ill
effect develops.
5 FIRE-FIGHTING MEASURES
: On exposure to high temperature, may decompose, releasing toxic gases.
Specific hazards
: Carbon dioxide.
Hazardous combustion products
Sulphur dioxide.
Nitrogen oxides.
: Use extinguishing media appropriate for surrounding fire.
Extinguishing media
BIOWEST In case of emergency : ORFILA (0)1 45 42 59 59
Rue de la Caille FR-49340 NUAILLE FRANCE
Tel : +33 2 41 46 42 42
Page : 2
SAFETY DATA SHEET Revised edition no : 1
Date : 16 / 12 / 2009
Supersedes : 0 / 0 / 0
Hepes, Cell Culture tested P5455
5 FIRE-FIGHTING MEASURES (continued)
: Use water spray or fog for cooling exposed containers.
Surrounding fires
: Wear proper protective equipment.
Protection against fire
: Exercise caution when fighting any chemical fire.
Special procedures
6 ACCIDENTAL RELEASE MEASURES
: Suitable respiratory equipment. Minimize generation of dust.
Personal precautions
: Prevent entry to sewers and public waters.
Environmental precautions
: Collect spills and put it into appropriated container.
Clean up methods
7 HANDLING AND STORAGE
: Use good housekeeping practices to avoid rendering dust airborne.
General
: Store in dry, cool, well-ventilated area.
Storage
: Where contact with eyes or skin is likely, wear suitable protection. Use only in well
Handling
ventilated areas.
8 EXPOSURE CONTROLS/PERSONAL PROTECTION
Personal protection
: Approved dust or mist respirator should be used if airborne particles are generated
- Respiratory protection
when handling this material.
: Gloves.
- Hand protection
: Wear suitable protective clothing.
- Skin protection
: Goggles.
- Eye protection
9 PHYSICAL AND CHEMICAL PROPERTIES
: Powder.
Physical state at 20 癈
: White.
Colour
: Barely perceptible.
Odour
: -0.4070
Log P octanol / water at 20癈
10 STABILITY AND REACTIVITY
: Stable.
Stability and reactivity
: When heated to decomposition, emits dangerous fumes.
Hazardous decomposition products
11 TOXICOLOGICAL INFORMATION
: > 316
Rat oral LD50 [mg/kg]
: No significant signs or symptoms indicative of any adverse health hazard are
Sensitization
expected to occur as a result of ingestion.
: No adverse health effects were noted.
Carcinogenicity
: No adverse health effects were noted.
Mutagenicity
BIOWEST In case of emergency : ORFILA (0)1 45 42 59 59
Rue de la Caille FR-49340 NUAILLE FRANCE
Tel : +33 2 41 46 42 42
Page : 3
SAFETY DATA SHEET Revised edition no : 1
Date : 16 / 12 / 2009
Supersedes : 0 / 0 / 0
Hepes, Cell Culture tested P5455
11 TOXICOLOGICAL INFORMATION (continued)
: No adverse health effects were noted.
Toxic for reproduction : Fertility
12 ECOLOGICAL INFORMATION
: No specific risk for the environment.
Ecological effects information
13 DISPOSAL CONSIDERATIONS
: Dispose in a safe manner in accordance with local/national regulations.
General
14 TRANSPORT INFORMATION
: Not regulated.
General information
15 REGULATORY INFORMATION
: Xi : Irritant
Symbol(s)
: R36/37/38 : Irritating to eyes, respiratory system and skin.
R Phrase(s)
: S22 : Do not breathe dust.
S Phrase(s)
S24 : Avoid contact with skin.
S26 : In case of contact with eyes, rinse immediately with plenty of water and seek
medical advice.
S35 : This material and its container must be disposed of in a safe way.
S36/37 : Wear suitable protective clothing and gloves.
S51 : Use only in well-ventilated areas.
S59 : Refer to manufacturer/supplier for information on recovery/recycling.
16 OTHER INFORMATION
: None.
Further information
The contents and format of this SDS are in accordance with REGULATION (EC) No 1907/2006 OF THE EUROPEAN
PARLIAMENT AND OF THE COUNCIL
DISCLAIMER OF LIABILITY The information in this SDS was obtained from sources which we believe are reliable. However, the
information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of
handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other
reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way
connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this
product. If the product is used as a component in another product, this MSDS information may not be applicable.
End of document
BIOWEST In case of emergency : ORFILA (0)1 45 42 59 59
Rue de la Caille FR-49340 NUAILLE FRANCE
Tel : +33 2 41 46 42 42
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