Nufarm
NUFARM AGRICULTURE INC.
1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
SUPPLIED BY:
Nufarm Agriculture Inc.
5507 1st Street, SE
Calgary, AB. T2H 1H9
Phone Number: (403)-253-8471
Fax Number: (403)-253-8478
MANUFACTURED BY:
Nufarm Agriculture Inc.
5507 1st Street, SE
Calgary, AB T2H 1H9
Phone Number: (403)-253-8471
Fax Number: (403)-253-8478
Amitrol 240 Liquid Herbicide
PRODUCT:
PCP NUMBER: 25684
DATE PREPARED: January 6, 2009
PREPARER: Brent R. McLennan
CHEMICAL FAMILY/USE: Herbicide.
C2H4N4
FORMULA:
CHEMICAL SYNONYMS: Amitrole; aminotriazole; ATA; 1H-1,2,4-triazol-3-amine; 3-amino-s-triazole; 3-amino-1,2,4-
triazole; 1H-1,2,4-triazol-3-ylamine.
2. COMPOSITION/INFORMATION ON INGREDIENTS
Hazardous Ingredients Wt. % CAS NO.
Amitrole 19.5-21.5 61-82-5
Ammonium thiocyanate 18-20 1762-95-4
Surfactants and other proprietary ingredients 3-5 NA
Note: The other major ingredient in this product is water.
3. HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW: CAUTION-POISON. Keep out of reach of children. Avoid contact with skin, eyes and clothing.
Avoid breathing spray mist or vapours. Causes irritation to eyes. May cause skin irritation. Harmful if absorbed through the skin.
Harmful if swallowed or inhaled.
EFFECTS OF ACUTE EXPOSURE:
INGESTION: Harmful if swallowed. The active ingredient amitrole is of low acute toxicity, but the additive ammonium thiocyanate
may cause nausea, vomiting, gastrointestinal irritation, disorientation, weakness, low blood pressure, convulsions and muscle spasms.
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NUFARM AGRICULTURE INC.
SKIN CONTACT: The ammonium thiocyanate additive may cause irritation. Overexposure by skin absorption may cause symptoms
similar to those for ingestion.
INHALATION: May cause nosebleeds, irritation of the upper respiratory tract and symptoms similar to those from ingestion.
EYE CONTACT: May cause eye irritation.
MEDICAL CONDITIONS AGGRAVATED: Skin exposure may aggravate preexisting skin conditions. Inhalation of mist may
aggravate preexisting respiratory conditions. Amitrole and ammonium thiocyanate both can cause thyroid effects, which may
aggravate preexisting thyroid conditions.
SUBCHRONIC (TARGET ORGAN) EFFECTS: (An adverse effect with symptoms that develop slowly over a long period of
time): Repeated overexposure may cause thyroid effects such as enlargement, decrease in metabolic rate and hypothyroidism.
CHRONIC EFFECTS/CARCINOGENICITY: The International Agency for Research on Cancer (IARC) states that amitrole is
not classifiable as to its carcinogenicity in humans (Group 3). IARC concluded that amitrole produces thyroid tumours in mice and
rats by a non-genotoxic mechanism and would not be expected to produce thyroid cancer in humans exposed to concentrations that do
not alter thyroid hormone homeostasis. IARC further observed that liver tumours in mice and benign pituitary tumours in rats were
also produced by a non-genotoxic mechanism.
REPRODUCTIVE TOXICITY: In laboratory animal studies on amitrole, reproductive effects were observed, but only at doses
toxic to parental animals.
DEVELOPMENTAL TOXICITY: Studies with amitrole in laboratory animals have shown decreased fetal body weights and a
variety of variations in the offspring, but only at doses toxic to mother animals.
GENOTOXICTY: There have been some positive and some negative studies, but the weight of evidence from a series of well
documented studies is that amitrole is not mutagenic.
PRINCIPLE ROUTES OF EXPOSURE: Eye contact. Skin absorption. Inhalation. Oral.
TOXICOLOGICALLY SYNERGISTIC MATERIALS: None known.
OTHER: None known.
4. FIRST AID MEASURES
INGESTION: Contact a physician or Poison Control Centre at once. If swallowed and victim is conscious, give two glasses of water
to dilute stomach contents. Induce vomiting by sticking fingers down throat. Never give anything by mouth to an unconscious person.
SKIN: In case of contact, remove contaminated clothing and wash skin thoroughly with soap and water.
INHALATION: If inhaled, remove to fresh air and get medical attention or contact a Poison Control Centre.
EYES: If in eyes, flush immediately with clean water.
NOTE TO PHYSICIAN: No specific antidote. Main effect is anti-thyroid action. Treatment based on sound judgment of physician
and individual reactions of patient. Overexposure to materials other than this product may have occurred.
5. FIRE FIGHTING MEASURES
FLASH POINT: ....................................................................... > 100癈.
CONDITIONS OF FLAMMABILITY: ................................ NAp.
FLAMMABLE LIMITS IN AIR - Upper (%): ..................... NAp
FLAMMABLE LIMITS IN AIR - Lower (%):..................... NAp
AUTOIGNITION TEMPERATURE: .................................. NAp
SENSITIVITY TO MECHANICAL IMPACT (Y/N): ......... NA. No sensitivity expected based on long handling history.
SENSITIVITY TO STATIC DISCHARGE: ........................ NA. No sensitivity expected based on long handling history.
EXTINGUISHING MEDIA: Water fog, alcohol foam, carbon dioxide, dry chemical.
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NUFARM AGRICULTURE INC.
SPECIAL FIREFIGHTING PROCEDURES: Firefighters should wear self-contained breathing apparatus and full protective
clothing when fighting chemical fires. Minimize and contain water runoff.
6. ACCIDENTAL RELEASE MEASURES
ACTION TO BE TAKEN IF MATERIAL IS RELEASED OR SPILLED: Use safety equipment and procedures appropriate to
the size of the spill. Keep unnecessary people away. Avoid runoff to natural waters and sewers. Surround and absorb spills with inert
material such as perlite, sawdust, clay granules, vermiculite, sand or dirt. Contain all affected material in a closed, labeled container
for proper disposal. Isolate from other waste materials. Clean contaminated area such as hard surfaces with detergent and water,
collecting cleaning solution for proper disposal. Large spills to soil or similar surfaces may necessitate removal of top soil.
7. HANDLING AND STORAGE
PRECAUTIONS TO BE TAKEN IN HANDLING AND STORAGE: Keep from freezing. Store at temperatures above freezing
point (see Section 9) and preferably above 0癈. Keep away from food and feed products. Avoid storage in close proximity to
insecticides, fungicides, fertilizers, plants and seeds. Avoid contact with eyes, skin and clothing. Keep container tightly closed when
not in use.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
EXPOSURE LIMITS:
Hazardous Ingredients TWA* STEL Units
ACGIH TLV?br>
mg/M3
Amitrole N/E 0.2 N/E
mg/M3
Ammonium thiocyanate 5** (skin) N/E N/E
*8-hour TWA unless otherwise noted
**Based on established limit for cyanides as CN
ENGINEERING CONTROLS: Use in a well ventilated area. General ventilation with a good source of make-up air recommended
as minimum for indoor situations. Ventilation should be adequate to maintain air concentrations below exposure limits.
RESPIRATORY PROTECTION EQUIPMENT: Use an approved pesticide respirator if ventilation is not adequate or exposure to
sprays, mists or vapours is likely.
PROTECTIVE GLOVES: All types of chemical-resistant gloves for handling chemicals are acceptable, provided that they can be
cleaned. Rinse gloves before removal.
EYE AND FACE PROTECTION: Goggles or face shield when handling concentrate.
OTHER PROTECTIVE EQUIPMENT: Long sleeved shirt, long pants, socks and shoes are minimum work clothing. Use other
equipment appropriate to specific situation.
VENTILATION: Use only in well ventilated area.
Nufarm
NUFARM AGRICULTURE INC.
9. PHYSICAL AND CHEMICAL PROPERTIES
NOTE: Physical data are typical values, but may vary from sample to sample. A typical value should not be construed as a
guaranteed analysis or as a specification.
BOILING POINT: ................................................................... NA. Expected to be similar to water: >100癈.
VAPOR PRESSURE: .............................................................. NA. Product expected to be similar to water.
VAPOR DENSITY (air = 1): .................................................. NA.
FREEZING POINT:................................................................ -12.2癈.
MELTING POINT: ................................................................ NA. (Amitrole 159癈.)
PHYSICAL STATE: ............................................................... Liquid.
ODOUR: ................................................................................... Mildly sweet and ammoniacal.
COLOUR: ................................................................................ Dark Brown.
ODOR THRESHOLD (ppm): ................................................ NA
EVAPORATION RATE (butyl acetate = 1): ........................ NA
SPECIFIC GRAVITY (water = 1): ........................................ 1.12
DENSITY @ 25癈: .................................................................. 1.12
pH:............................................................................................. Approximately 6-7
SOLUBILITY IN WATER (20癈):........................................ Soluble.
COEFFICIENT OF WATER/OIL DISTRIBUTION: ......... NA. Product water soluble.
10. STABILITY AND REACTIVITY
STABILITY: Stable.
HAZARDOUS POLYMERIZATION: Will not occur.
HAZARDOUS THERMAL DECOMPOSITION/COMBUSTION PRODUCTS: Hydrogen cyanide, other cyanide compounds,
hydrogen sulfide, sulfur dioxide, hydrogen, ammonia, oxides of carbon, oxides of nitrogen and other potentially toxic combustion
products may be present.
INCOMPATIBILITY (MATERIALS TO AVOID): Avoid contact with strong acidic, basic or oxidizing agents. Toxic products
can be generated and violent reaction possible in extreme case. Amitrole is mildly corrosive to iron, aluminum, copper and copper
alloys.
CONDITIONS TO AVOID: None known.
11. TOXICOLOGICAL INFORMATION
Data are from laboratory studies conducted on technical amitrole:
ACUTE ORAL LD50 (mg/kg): ................................................ 24,600 (Rat)
ACUTE DERMAL LD50 (mg/kg): .......................................... > 10,000 (Rabbit)
ACUTE INHALATION LC50 (mg/l): ..................................... NA.
OTHER: Tested as slightly irritating to the eye (Rabbit) and nonirritating to the skin (Rabbit)
Data are from laboratory studies conducted on ammonium thiocyanate:
ACUTE ORAL LD50 (mg/kg): ................................................ 750 (Rat)
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NUFARM AGRICULTURE INC.
12. ECOLOGICAL INFORMATION
ECOTOXICOLOGICAL INFORMATION:
Data on amitrole technical:
> 1000 (Rainbow Trout)
96-HOUR LC50 (mg/L):
> 1000 (Bluegill)
96-HOUR LC50 (mg/L):
18 (Daphnia)
48-HOUR EC50 (mg/L):
> 5000 (Bobwhite Quail)
DIETARY LC50 (ppm):
> 5000 (Mallard Duck)
DIETARY LC50 (ppm):
Data on ammonium thiocyanate:
100 (Fathead Minnow)
96-HOUR LC50 (mg/L):
420 (Mosquito Fish)
48-HOUR LC50 (mg/L):
170 (Daphnia)
96-HOUR EC50 (mg/L):
CHEMICAL FATE INFORMATION: At usual application rates, amitrole is microbially degraded with a typical half-life of 2 to 3
weeks.
13. DISPOSAL CONSIDERATIONS
DISPOSAL METHOD: For information on disposal of unused, unwanted product, contact the manufacturer or the provincial
regulatory agency. Disposal should be made in accordance with federal, provincial and local regulations. Contact the manufacturer
and the provincial regulatory agency in case of a spill, and for clean up of spills.
Emptied container retains vapor and product residue. Observe all labeled safeguards until container is cleaned, reconditioned or
destroyed. Do not reuse container for any purpose. If applicable, return container in accordance with return program. If a recyclable
container, dispose of at a container collection site. Contact local distributor, dealer or municipality for the location of the nearest
collection site. Before taking the container to the collection site, triple or pressure rinse the empty container adding rinsings to spray
tank, and make container unsuitable for further use. If there is no container collection site in your area, dispose of the container in
accordance with provincial requirements.
14. TRANSPORT INFORMATION
CANADIAN TDG DESCRIPTION (Road & Rail): Not regulated. Contact manufacturer for updates to transport information.
15. REGULATORY INFORMATION
WHMIS HAZARD CLASS: D2B Toxic Material
WHMIS TRADE SECRET: Exempt. (This product is regulated under the Pest Control Products Act - WHMIS exempt.)
CANADIAN INVENTORY: This product is currently exempt from CEPA.
HAZARD RATING SYSTEMS:
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NUFARM AGRICULTURE INC.
HMIS: Not Available
National Fire Protection Association (NFPA? Hazard Ratings:
Ratings for This Product Key to Ratings
2 Health Hazard 0 Minimal
1 Flammability 1 Slight
1 Instability 2 Moderate
3 Serious
4 Severe
16. OTHER INFORMATION
REVISIONS:
The following has been revised since the last issue of this MSDS: Section 1 revision.
ADDITIONAL INFORMATION:
Abbreviations used throughout the MSDS are: NA = Not available
NAp = Not applicable
N/E = None Established.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS
contains all of the information required by the CPR.
Company references utilized in preparation of the MSDS.
***END OF MSDS***
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