Material Data Safety Sheet
AutoGen, Inc.
84 October Hill Rd.
Holliston, MA 01746
(800) 292-5678
Date revised: 7-22-04
Emergency Telephone Number: (800) 424-9300
Agent: CHEMTREC
Section 1 ?Product and Company Information
Product Name: AGP245(T) Tissue RNA - Tissue Homogenization Solution R-A
Product Number: TR-S0
Company: AutoGen, Inc.
Address: 84 October Hill Rd.
Holliston, MA 01746
Phone: (800) 292-5678 or (508) 429-5965
Fax: (508) 429-9765
Section 2 ?Composition/Information on Ingredients
Chemical name CAS #
Guanidine Thiocyanate 593-84-0
Laurylsarcosine 137-16-6
Phenol 108-95-2
Section 3 - Hazards Identification
Emergency overview
Corrosive
Highly Toxic
Suspected Carcinogen
Section 4- First Aid Measures
Ingestion
Drink 1 glass of water followed by 1 glass of milk. Get medical attention
immediately
Inhalation
Remove to fresh air. If breathing is impaired give oxygen. If breathing has
stopped, give artificial respiration and contact emergency medical personnel.
Skin Contact
Remove phenol with undiluted polyethylene glycol 300 to 400 or isopropyl
alcohol. Wash with copious amounts of water. Remove contaminated clothing
and contact a physician.
Eye contact
Flush with water for 15 minutes and contact a physician.
Wash contaminated clothing before reuse.
Section 5- Fire Fighting Measures
Extinguishing Media
Water spray, carbon dioxide, dry chemical powder, or alcohol resistant foam
Firefighting
Protective Equipment
Wear self-contained breathing apparatus and protective clothing to prevent
contact with skin and eyes
Special Procedures
Use water spray to cool fire-exposed containers
Specific Hazards
Vapor may travel a considerable distance to source of ignition and flashback
Emits toxic fumes
Section 6 ?Accidental Release Measures
Procedures in case of accidental leak or spill
Evacuate area
Shut off all sources of ignition
Personal Precaution Equipment
Wear self-contained breathing apparatus, rubber boots, and heavy rubber
gloves
Clean-up procedures
Cover with dry-lime, sand or soda ash. Place in covered containers, using non-
sparking tools. Transport outdoors. Ventilate area and wash spill site after
material pick-up is complete.
Section 7 ?Handling and Storage
Handling
Wear appropriate safety equipment. Especially chemical resistant gloves, safety
goggles, and other protective clothing. In very special cases, NIOSH/MSHA-
approved respirator may be required. Avoid contact with eyes, skin and
clothing. Avoid prolonged or repeated exposure. Do not breathe vapor.
Storage
Room temperature. Keep away from heat, sparks, and open flame, or other
sources of ignition.
Section 8 ?Exposure controls/Personal Protection
Personal Protective Equipment
Respiratory
NIOSH-approved respirator
Hand
Compatible chemical-resistant gloves
Eye
Chemical safety goggles
General hygiene measures
Wash hands thoroughly after handling
Section 9 ?Physical and Chemical Properties
Appearance
Physical State: liquid
Color: clear
Form: N/A
Characteristics
Molecular weight:
BP/BP range:
MP/MP range:
Freezing point:
Vapor Pressure:
Vapor Density:
Saturated vapor conc.:
SG/Density:
Bulk density:
Odor Threshold:
Volatile%:
V O C Content:
Water Content:
Solvent Content:
Evaporation Rate:
Viscosity:
Partition Coefficient:
Decomposition Temp.:
Flash Point F:
Flash Point C:
Explosion limits:
Flammability:
Autoignition Temp:
Section 10 ?Stability and Reactivity
Stability
Stable
Incompatible agents
Oxidizing agents, high temperatures, visible light, acids.
Hazardous decomposition products
Ammonia, Nitrogen oxides, Sulfur containing gases, Hydrogen cyanide, Carbon
monoxide, carbon dioxide., toxic gases.
Hazardous polymerization
Will not occur.
Section 11 ?Toxicological Information
RETCS
Component Number
Guanidine Thiocyanate XL1225000
Laurylsarcosine
Phenol SJ3325000
Routes of exposure
May be harmful by inhalation, ingestion, or skin absorption
Possible effects
Irritation of the skin, eyes, mucous membranes, and upper respiratory tract.
CNS depression. Nausea, headache and vomiting. Narcotic effects. Damage
to the heart.
Target organs
Nerves, Lungs, Liver, Heart, Kidneys, CNS, and respiratory tract.
Section 12 ?Ecological Information
Data not available.
Section 13 ?Disposal Considerations
General Instructions
Burn in a chemical incinerator equipped with an afterburner and scrubber but
exert extra care in igniting, as this material is highly flammable.
Observe all Federal, State, and Local environmental regulations.
Section 14 ?Transport Information
UN number: 2810
Proper shipping name: Toxic liquid, organic, n.o.s.
Hazard Class: 6.1
Hazard subclass:
Packing group: III
Section 15 ?Regulatory Information
EU Directives Classification
Risk Statements
R: 24/25 34
Very toxic by contact with skin and ingestion. Causes Burns.
Safety Statements
S: 1 2 28 45
Section 16 ?Other Information
Disclaimer
For R&D use only. Not for drug, household, or other uses.
Warranty
The factual information contained in this material safety data sheet is believed
to be accurate and reflects, to the best of our knowledge, the currently
available data pertaining to the chemicals. This information may be incomplete
and is used only as a guide. Users are encouraged to investigate the suitability
of the information with respect to their application. AutoGen, Inc. assumes no
responsibility resulting from the use or handling of this compound.
Material Data Safety Sheet
AutoGen, Inc.
84 October Hill Rd.
Holliston, MA 01746
(800) 292-5678
Date revised: 07-22-04
Emergency Telephone Number: (800) 424-9300
Agent: CHEMTREC
Section 1 ?Product and Company Information
Product Name: AGP245(T) Tissue RNA - Tissue Lysis Solution R-B
Product Number: TR-S1
Company: AutoGen, Inc.
Address: 84 October Hill Rd.
Holliston, MA 01746
Phone: (800) 292-5678
Fax: (508) 429-9765
Section 2 ?Composition/Information on Ingredients
Chemical name CAS #
Sodium Acetate 127-09-3
Section 3 - Hazards Identification
Emergency overview
Caution: Avoid contact and inhalation
HMIS Rating
Health: 1
Flammability: 0
Reactivity: 1
NFPA Rating
Health: 1
Flammability: 0
Reactivity: 1
Section 4- First Aid Measures
Oral Exposure
If swallowed, wash out mouth with water provided person is conscious. Call a
physician.
Inhalation
Remove to fresh air. If breathing is impaired give oxygen. If breathing has
stopped, give artificial respiration and contact emergency medical personnel.
Skin Contact
Wash with copious amounts of water. Remove contaminated clothing and
contact a physician.
Eye contact
Flush with water for 15 minutes and contact a physician.
Wash contaminated clothing before reuse.
Section 5- Fire Fighting Measures
Extinguishing Media
Water spray, carbon dioxide, dry chemical powder, or appropriate foam.
Firefighting
Protective Equipment
Wear self-contained breathing apparatus and protective clothing to prevent
contact with skin and eyes
Special Procedures
Use water spray to cool fire-exposed containers
Specific Hazards
Emits toxic fumes under fire conditions.
Section 6 ?Accidental Release Measures
Personal Precaution Equipment
Use procedures to minimize direct contact with skin or eyes and prevent
inhalation of dust.
Clean-up procedures
Sweep up, place in a bag and hold for waste disposal. Ventilate area and clean
up using appropriate procedures.
Section 7 ?Handling and Storage
Handling
Avoid inhalation. Avoid contact with eyes, skin and clothing. Avoid prolonged
or repeated exposure.
Storage
Room temperature.
Section 8 ?Exposure controls/Personal Protection
Personal Protective Equipment
Respiratory
Dust mask
Hand
Compatible chemical-resistant gloves
Eye
Chemical safety goggles
General hygiene measures
Wash hands thoroughly after handling
Section 9 ?Physical and Chemical Properties
Appearance
Physical State: liquid
Color: clear
Form: N/A
Characteristics
Molecular weight: 82.03
BP/BP range:
MP/MP range: 300癈
Freezing point:
Vapor Pressure:
Vapor Density:
Saturated vapor conc.:
SG/Density: 1.528 g/cm3
Bulk density: 320-470 kg/l
Odor Threshold:
Volatile%:
V O C Content:
Water Content:
Solvent Content:
Evaporation Rate:
Viscosity:
Partition Coefficient: Log Kow: -4.22
Decomposition Temp: 324癈
Flash Point F: > 480
Flash Point C: > 250
Explosion limits:
Flammability:
Autoignition Temp: 600癈
Section 10 ?Stability and Reactivity
Stability
Stable
Incompatible agents
Strong oxidizing agents.
Hazardous decomposition products
Carbon monoxide, carbon dioxide.
Hazardous polymerization
Will not occur.
Section 11 ?Toxicological Information
RETCS
Component Number
Sodium Acetate AJ4300010
Routes of exposure
May be harmful by inhalation, ingestion, or skin absorption
Possible effects
Irritation of the skin, eyes, mucous membranes, and upper respiratory tract.
CNS depression. Abdominal pain, headache and vomiting.
Section 12 ?Ecological Information
Data not available.
Section 13 ?Disposal Considerations
General Instructions
Burn in a chemical incinerator equipped with an afterburner and scrubber but
exert extra care in igniting, as this material is highly flammable.
Observe all Federal, State, and Local environmental regulations.
Section 14 ?Transport Information
UN number: None
Proper shipping name: None
Hazard Class: None
Hazard subclass: None
Packing group: None
DOT: This substance is considered non-hazardous for transport.
IATA: This substance is non-hazardous for Air transport.
Section 15 ?Regulatory Information
EU Directives Classification
Safety Statements
S: 22 24/25
Do not breathe dust. Avoid contact with skin and eyes.
Section 16 ?Other Information
Disclaimer
For R&D use only. Not for drug, household, or other uses.
Warranty
The factual information contained in this material safety data sheet is believed
to be accurate and reflects, to the best of our knowledge, the currently
available data pertaining to the chemicals. This information may be incomplete
and is used only as a guide. Users are encouraged to investigate the suitability
of the information with respect to their application. AutoGen, Inc. assumes no
responsibility resulting from the use or handling of this compound.
Material Data Safety Sheet
AutoGen, Inc.
84 October Hill Rd.
Holliston, MA 01746
(800) 292-5678
Date revised: 02-11-04
Emergency Telephone Number: (800) 424-9300
Agent: CHEMTREC
Section 1 ?Product and Company Information
Product Name: AGP245(T) Tissue RNA - Tissue Denaturing Solution B
Product Number: TR-S2
Company: AutoGen, Inc.
Address: 84 October Hill Rd.
Holliston, MA 01746
Phone: (800) 292-5678
Fax: (508) 429-9765
Section 2 ?Composition/Information on Ingredients
Chemical name CAS #
Chloroform 67-66-3
Section 3 - Hazards Identification
Emergency overview
Highly Toxic
Suspected Carcinogen
Target organs: Nerves, Liver, Heart, CNS, Kidneys, and Teeth
Section 4- First Aid Measures
Ingestion
Get medical attention immediately
Inhalation
Remove to fresh air. If breathing is impaired give oxygen. If breathing has
stopped, give artificial respiration and contact emergency medical personnel.
Skin Contact
Wash with copious amounts of water. Remove contaminated clothing and
contact a physician.
Eye contact
Flush with water for 15 minutes and contact a physician.
Wash contaminated clothing before reuse.
Section 5- Fire Fighting Measures
Extinguishing Media
Carbon dioxide, Dry Chemical Powder, or appropriate foam
Firefighting
Protective Equipment
Wear self-contained breathing apparatus and protective clothing to prevent
contact with skin and eyes
Special Procedures
Use water spray to cool fire-exposed containers
Specific Hazards
Vapor may travel a considerable distance to source of ignition and flashback
Section 6 ?Accidental Release Measures
Procedures in case of accidental leak or spill
Evacuate area
Shut off all sources of ignition
Personal Precaution Equipment
Wear self-contained breathing apparatus, rubber boots, and heavy rubber
gloves
Clean-up procedures
Cover with dry-lime, sand or soda ash. Place in covered containers, using non-
sparking tools. Transport outdoors. Ventilate area and wash spill site after
material pick-up is complete.
Section 7 ?Handling and Storage
Handling
Wear appropriate safety equipment. Especially chemical resistant gloves, safety
goggles, and other protective clothing. In very special cases, NIOSH/MSHA-
approved respirator may be required. Avoid contact with eyes, skin and
clothing. Avoid prolonged or repeated exposure. Do not breathe vapor.
Storage
Place at 4癈 for storage under 1 month. Place at -20癈 for long-term storage.
Keep tightly closed. Keep away from heat, sparks, and open flame.
Section 8 ?Exposure controls/Personal Protection
Personal Protective Equipment
Respiratory
NIOSH-approved respirator
Hand
Compatible chemical-resistant gloves
Eye
Chemical safety goggles
General hygiene measures
Wash hands thoroughly after handling
Section 9 ?Physical and Chemical Properties
Appearance
Physical State: liquid
Color: dilute yellow
Form: N/A
Characteristics
Molecular weight:
BP/BP range:
MP/MP range:
Freezing point:
Vapor Pressure:
Vapor Density:
Saturated vapor conc.:
SG/Density:
Bulk density:
Odor Threshold:
Volatile%:
V O C Content:
Water Content:
Solvent Content:
Evaporation Rate:
Viscosity:
Partition Coefficient:
Decomposition Temp.:
Flash Point F:
Flash Point C:
Explosion limits:
Flammability:
Autoignition Temp:
Section 10 ?Stability and Reactivity
Stability
Stable
Incompatible agents
Oxidizing agents, peroxides, acids, acid chlorides, acid anhydrides, alkali
metals, ammonia
Hazardous decomposition products
Carbon monoxide, carbon dioxide.
Hazardous polymerization
Will not occur.
Section 11 ?Toxicological Information
RETCS
Component Number
Chloroform FS9100000
Routes of exposure
May be harmful by inhalation, ingestion, or skin absorption
Possible effects
Irritation of the skin, eyes, mucous membranes, and upper respiratory tract.
CNS depression. Nausea, headache and vomiting. Narcotic effects. Damage
to the heart.
Target organs
Nerves, Liver, Heart, Kidneys, CNS, and Teeth.
Section 12 ?Ecological Information
Data not available.
Section 13 ?Disposal Considerations
General Instructions
Burn in a chemical incinerator equipped with an afterburner and scrubber but
exert extra care in igniting, as this material is highly flammable.
Observe all Federal, State, and Local environmental regulations.
Section 14 ?Transport Information
UN number:
Proper shipping name:
Hazard Class:
Hazard subclass:
Packing group:
Section 15 ?Regulatory Information
EU Directives Classification
Risk Statements
R: 10 26/27/28 34 45
Flammable. Very toxic by Inhalation, contact with skin and ingestion. Causes
Burns. May cause cancer.
Safety Statements
S: 15 36/37/38
Wear suitable protective clothing, gloves, and eye/face protection. Keep away
from heat.
Section 16 ?Other Information
Disclaimer
For R&D use only. Not for drug, household, or other uses.
Warranty
The factual information contained in this material safety data sheet is believed
to be accurate and reflects, to the best of our knowledge, the currently
available data pertaining to the chemicals. This information may be incomplete
and is used only as a guide. Users are encouraged to investigate the suitability
of the information with respect to their application. AutoGen, Inc. assumes no
responsibility resulting from the use or handling of this compound.
Material Data Safety Sheet
AutoGen, Inc.
84 October Hill Rd.
Holliston, MA 01746
(800) 292-5678
Date revised: 02-19-04
Emergency Telephone Number: (800) 424-9300
Agent: CHEMTREC
Section 1 ?Product and Company Information
Product Name: AGP245(T) Tissue RNA - RNA Precipitation Solution A
Product Number: TR-S4
Company: AutoGen, Inc.
Address: 84 October Hill Rd.
Holliston, MA 01746
Phone: (800) 292-5678
Fax: (508) 429-9765
Section 2 ?Composition/Information on Ingredients
Chemical name CAS #
Isopropanol 66-63-0
Section 3 - Hazards Identification
Emergency overview
Flammable
Irritant
Target organs: Nerves, Kidneys.
HMIS Rating
Health: 2 (additional chronic hazards present)
Flammability: 3
Reactivity: 1
NFPA Rating
Health: 2
Flammability: 3
Reactivity: 1
Section 4- First Aid Measures
Ingestion
Wash mouth with water. Call physician.
Inhalation
Remove to fresh air. If breathing is impaired give oxygen. If breathing has
stopped, give artificial respiration and contact emergency medical personnel.
Skin Contact
Wash with copious amounts of water. Remove contaminated clothing and
contact a physician.
Eye contact
Flush with water for 15 minutes and contact a physician.
Wash contaminated clothing before reuse.
Section 5- Fire Fighting Measures
Extinguishing Media
Water spray, Carbon dioxide, Dry Chemical Powder, or appropriate foam
Firefighting
Protective Equipment
Wear self-contained breathing apparatus and protective clothing to prevent
contact with skin and eyes
Special Procedures
Use water spray to cool fire-exposed containers
Specific Hazards
Explosion hazard. Flashback hazard.
Section 6 ?Accidental Release Measures
Procedures in case of accidental leak or spill
Evacuate area
Shut off all sources of ignition
Personal Precaution Equipment
Wear self-contained breathing apparatus, rubber boots, and heavy rubber
gloves
Clean-up procedures
Cover with dry-lime, sand or soda ash. Place in covered containers, using non-
sparking tools. Transport outdoors. Ventilate area and wash spill site after
material pick-up is complete.
Section 7 ?Handling and Storage
Handling
Wear appropriate safety equipment. Especially chemical resistant gloves, safety
goggles, and other protective clothing. In very special cases, NIOSH/MSHA-
approved respirator may be required. Avoid contact with eyes, skin and
clothing. Avoid prolonged or repeated exposure. Do not breathe vapor.
Storage
Room temperature. Keep tightly closed. Keep away from heat, sparks, and
open flame.
Section 8 ?Exposure controls/Personal Protection
Personal Protective Equipment
Respiratory
NIOSH-approved respirator
Hand
Compatible chemical-resistant gloves
Eye
Chemical safety goggles
General hygiene measures
Wash hands thoroughly after handling
Section 9 ?Physical and Chemical Properties
Appearance
Physical State: liquid
Color: colorless
Form: N/A
Characteristics
Molecular weight: 60.1
BP/BP range: 81-83癈
MP/MP range: -89.5癈
Freezing point: -88癈
Vapor Pressure: 33 mmHg @ 20癈
Vapor Density: 2.1 g/l
Saturated vapor conc.: N/A
SG/Density: 0.785 g/cm3
Bulk density: N/A
Odor Threshold: N/A
Volatile%: N/A
V O C Content: N/A
Water Content:
Solvent Content: N/A
Evaporation Rate: 3
Viscosity: 2.27 Pas @ 20癈
Partition Coefficient: Log Kow: 0.05
Decomposition Temp: N/A
Flash Point F: 53癋
Flash Point C: 12癈
Explosion limits: lower 2.5%
Upper 12%
Flammability: N/A
Autoignition Temp: 300癈
Section 10 ?Stability and Reactivity
Stability
Stable (may form peroxides of unknown stability).
Incompatible agents
Oxidizing agents, acids, acid anhydrides, Halogens, Aluminum
Hazardous decomposition products
Carbon monoxide, carbon dioxide.
Hazardous polymerization
Will not occur.
Section 11 ?Toxicological Information
RETCS
Component Number
Isopropanol NT8050000
Routes of exposure
May be harmful by inhalation, ingestion, or skin absorption
Possible effects
Irritation of the skin, eyes, mucous membranes, and upper respiratory tract.
CNS depression. Nausea, headache and vomiting. Narcotic effects.
Target organs
Nerves, Liver, Heart, Kidneys, CNS, GI system.
Section 12 ?Ecological Information
Data not available.
Section 13 ?Disposal Considerations
General Instructions
Burn in a chemical incinerator equipped with an afterburner and scrubber but
exert extra care in igniting, as this material is highly flammable.
Observe all Federal, State, and Local environmental regulations.
Section 14 ?Transport Information
UN number: UN1993
Proper shipping name: flammable liquid, n.o.s
Hazard Class: 3
Hazard subclass: N/A
Packing group: II
Section 15 ?Regulatory Information
EU Directives Classification
Risk Statements
R: 11 36 57
Flammable. Very toxic by Inhalation, contact with skin and ingestion. Causes
Burns. May cause cancer.
Safety Statements
S: 7 16 24/25 26
Wear suitable protective clothing, gloves, and eye/face protection. Keep away
from heat.
Section 16 ?Other Information
Disclaimer
For R&D use only. Not for drug, household, or other uses.
Warranty
The factual information contained in this material safety data sheet is believed
to be accurate and reflects, to the best of our knowledge, the currently
available data pertaining to the chemicals. This information may be incomplete
and is used only as a guide. Users are encouraged to investigate the suitability
of the information with respect to their application. AutoGen, Inc. assumes no
responsibility resulting from the use or handling of this compound.
Material Data Safety Sheet
AutoGen, Inc.
84 October Hill Rd.
Holliston, MA 01746
(800) 292-5678
Date revised: 02-19-04
Emergency Telephone Number: (800) 424-9300
Agent: CHEMTREC
Section 1 ?Product and Company Information
Product Name: AGP245(T) Tissue RNA - RNA Wash Solution A
Product Number: TR-5/6
Company: AutoGen, Inc.
Address: 84 October Hill Rd.
Holliston, MA 01746
Phone: (800) 292-5678
Fax: (508) 429-9765
Section 2 ?Composition/Information on Ingredients
Chemical name CAS #
Ethanol 64-17-5
Section 3 - Hazards Identification
Emergency overview
Highly Toxic
Suspected Carcinogen
Target organs: Nerves, Liver, Heart, CNS, Kidneys, and Teeth
Section 4- First Aid Measures
Ingestion
Get medical attention immediately
Inhalation
Remove to fresh air. If breathing is impaired give oxygen. If breathing has
stopped, give artificial respiration and contact emergency medical personnel.
Skin Contact
Wash with copious amounts of water. Remove contaminated clothing and
contact a physician.
Eye contact
Flush with water for 15 minutes and contact a physician.
Wash contaminated clothing before reuse.
Section 5- Fire Fighting Measures
Extinguishing Media
Carbon dioxide, Dry Chemical Powder, or appropriate foam
Firefighting
Protective Equipment
Wear self-contained breathing apparatus and protective clothing to prevent
contact with skin and eyes
Special Procedures
Use water spray to cool fire-exposed containers
Specific Hazards
Vapor may travel a considerable distance to source of ignition and flashback
Section 6 ?Accidental Release Measures
Procedures in case of accidental leak or spill
Evacuate area
Shut off all sources of ignition
Personal Precaution Equipment
Wear self-contained breathing apparatus, rubber boots, and heavy rubber
gloves
Clean-up procedures
Cover with dry-lime, sand or soda ash. Place in covered containers, using non-
sparking tools. Transport outdoors. Ventilate area and wash spill site after
material pick-up is complete.
Section 7 ?Handling and Storage
Handling
Wear appropriate safety equipment. Especially chemical resistant gloves, safety
goggles, and other protective clothing. In very special cases, NIOSH/MSHA-
approved respirator may be required. Avoid contact with eyes, skin and
clothing. Avoid prolonged or repeated exposure. Do not breathe vapor.
Storage
Place at 4癈 for storage under 1 month. Place at -20癈 for long-term storage.
Keep tightly closed. Keep away from heat, sparks, and open flame.
Section 8 ?Exposure controls/Personal Protection
Personal Protective Equipment
Respiratory
NIOSH-approved respirator
Hand
Compatible chemical-resistant gloves
Eye
Chemical safety goggles
General hygiene measures
Wash hands thoroughly after handling
Section 9 ?Physical and Chemical Properties
Appearance
Physical State: liquid
Color: dilute yellow
Form: N/A
Characteristics
Molecular weight:
BP/BP range:
MP/MP range:
Freezing point:
Vapor Pressure:
Vapor Density:
Saturated vapor conc.:
SG/Density:
Bulk density:
Odor Threshold:
Volatile%:
V O C Content:
Water Content:
Solvent Content:
Evaporation Rate:
Viscosity:
Partition Coefficient:
Decomposition Temp.:
Flash Point F:
Flash Point C:
Explosion limits:
Flammability:
Autoignition Temp:
Section 10 ?Stability and Reactivity
Stability
Stable
Incompatible agents
Oxidizing agents, peroxides, acids, acid chlorides, acid anhydrides, alkali
metals, ammonia
Hazardous decomposition products
Carbon monoxide, carbon dioxide.
Hazardous polymerization
Will not occur.
Section 11 ?Toxicological Information
RETCS
Component Number
Ethanol KQ6300000
Routes of exposure
May be harmful by inhalation, ingestion, or skin absorption
Possible effects
Irritation of the skin, eyes, mucous membranes, and upper respiratory tract.
CNS depression. Nausea, headache and vomiting. Narcotic effects. Damage
to the heart.
Target organs
Nerves, Liver, Heart, Kidneys, CNS, and Teeth.
Section 12 ?Ecological Information
Data not available.
Section 13 ?Disposal Considerations
General Instructions
Burn in a chemical incinerator equipped with an afterburner and scrubber but
exert extra care in igniting, as this material is highly flammable.
Observe all Federal, State, and Local environmental regulations.
Section 14 ?Transport Information
UN number: UN1993
Proper shipping name: flammable liquid, n.o.s
Hazard Class: 3
Hazard subclass: N/A
Packing group: II
Section 15 ?Regulatory Information
EU Directives Classification
Risk Statements
R: 10 26/27/28 34 45
Flammable. Very toxic by Inhalation, contact with skin and ingestion. Causes
Burns. May cause cancer.
Safety Statements
S: 15 36/37/38
Wear suitable protective clothing, gloves, and eye/face protection. Keep away
from heat.
Section 16 ?Other Information
Disclaimer
For R&D use only. Not for drug, household, or other uses.
Warranty
The factual information contained in this material safety data sheet is believed
to be accurate and reflects, to the best of our knowledge, the currently
available data pertaining to the chemicals. This information may be incomplete
and is used only as a guide. Users are encouraged to investigate the suitability
of the information with respect to their application. AutoGen, Inc. assumes no
responsibility resulting from the use or handling of this compound.
Material Data Safety Sheet
AutoGen, Inc.
84 October Hill Rd.
Holliston, MA 01746
(800) 292-5678
Date revised: 08-22-05
Emergency Telephone Number: (800) 424-9300
Agent: CHEMTREC
Section 1 ?Product and Company Information
Product Name: AGP245(T) Tissue RNA - Drying Solution
Product Number: TR-S7
Company: AutoGen, Inc.
Address: 84 October Hill Rd.
Holliston, MA 01746
Phone: (800) 292-5678
Fax: (508) 429-9765
Section 2 ?Composition/Information on Ingredients
Chemical name CAS #
Ethanol (Ethyl alcohol) 64-17-5
Isopropanol (Isopropyl alcohol) 67-63-0
Methanol (Methyl alcohol) 67-56-1
Section 3 - Hazards Identification
Emergency overview
Highly Toxic
Causes severe eye irritation, moderate skin irritation
Suspected Carcinogen
Target organs: Eye, Blood, Nerves, Liver, Heart, Kidneys, and Teeth
Section 4- First Aid Measures
Ingestion
Get medical attention immediately
Inhalation
Remove to fresh air. If breathing is impaired give oxygen. If breathing has
stopped, give artificial respiration and contact emergency medical personnel.
Skin Contact
Wash with copious amounts of water. Remove contaminated clothing and
contact a physician.
Eye contact
Flush with water for 15 minutes and contact a physician.
Wash contaminated clothing before reuse.
Section 5- Fire Fighting Measures
Extinguishing Media
Carbon dioxide, Dry Chemical Powder, or appropriate foam
Firefighting
Protective Equipment
Wear self-contained breathing apparatus and protective clothing to prevent
contact with skin and eyes
Special Procedures
Use water spray to cool fire-exposed containers
Specific Hazards
Vapor may travel a considerable distance to source of ignition and flashback
Section 6 ?Accidental Release Measures
Procedures in case of accidental leak or spill
Evacuate area
Shut off all sources of ignition
Personal Precaution Equipment
Wear self-contained breathing apparatus, rubber boots, and heavy rubber
gloves
Clean-up procedures
Cover with dry-lime, sand or soda ash. Place in covered containers, using non-
sparking tools. Transport outdoors. Ventilate area and wash spill site after
material pick-up is complete.
Section 7 ?Handling and Storage
Handling
Wear appropriate safety equipment. Especially chemical resistant gloves, safety
goggles, and other protective clothing. In very special cases, NIOSH/MSHA-
approved respirator may be required. Avoid contact with eyes, skin and
clothing. Avoid prolonged or repeated exposure. Do not breathe vapor.
Storage
Place at 4癈 for storage under 1 month. Place at -20癈 for long-term storage.
Keep tightly closed. Keep away from heat, sparks, and open flame.
Section 8 ?Exposure controls/Personal Protection
Personal Protective Equipment
Respiratory
NIOSH-approved respirator
Hand
Compatible chemical-resistant gloves
Eye
Chemical safety goggles
General hygiene measures
Wash hands thoroughly after handling
Section 9 ?Physical and Chemical Properties
Appearance
Physical State: liquid
Color: colorless
Form: N/A
Characteristics
Molecular weight:
BP/BP range:
MP/MP range:
Freezing point:
Vapor Pressure: 42mm Hg
Vapor Density: 1.6
Saturated vapor conc.:
SG/Density:
Bulk density:
Odor Threshold:
Volatile%:
V O C Content:
Water Content:
Solvent Content:
Evaporation Rate:
Viscosity: N/A
Partition Coefficient:
Decomposition Temp.:
Flash Point F: 41F
Flash Point C: 5C
Explosion limits:4 ?20 vol %
Flammability: Highly Flammable
Autoignition Temp: 752F (400C)
Section 10 ?Stability and Reactivity
Stability
Stable
Incompatible agents
Oxidizing agents, peroxides, acids, acid chlorides, acid anhydrides, alkali metals,
ammonia
Hazardous decomposition products
Carbon monoxide, carbon dioxide.
Hazardous polymerization
Will not occur.
Section 11 ?Toxicological Information
RETCS
Component Number
Ethanol KQ6300000
Isopropanol NT8050000
Methanol PC1400000
Routes of exposure
May be harmful by inhalation, ingestion, or skin absorption
Possible effects
Irritation of the skin, eyes, mucous membranes, and upper respiratory tract.
CNS depression. Nausea, headache and vomiting. Narcotic effects. Damage
to the heart.
Target organs
Nerves, Liver, Heart, Kidneys, CNS, and Teeth.
Section 12 ?Ecological Information
Data not available.
Section 13 ?Disposal Considerations
General Instructions
Burn in a chemical incinerator equipped with an afterburner and scrubber but
exert extra care in igniting, as this material is highly flammable.
Observe all Federal, State, and Local environmental regulations.
Section 14 ?Transport Information
UN number: UN1993
Proper shipping name: flammable liquid, n.o.s
Hazard Class: 3
Hazard subclass: N/A
Packing group: II
Section 15 ?Regulatory Information
EU Directives Classification
Risk Statements
R: 10 26/27/28 34 45
Flammable. Very toxic by Inhalation, contact with skin and ingestion. Causes
Burns. May cause cancer.
Safety Statements
S: 15 36/37/38
Wear suitable protective clothing, gloves, and eye/face protection. Keep away
from heat.
Section 16 ?Other Information
Disclaimer
For R&D use only. Not for drug, household, or other uses.
Warranty
The factual information contained in this material safety data sheet is believed
to be accurate and reflects, to the best of our knowledge, the currently
available data pertaining to the chemicals. This information may be incomplete
and is used only as a guide. Users are encouraged to investigate the suitability
of the information with respect to their application. AutoGen, Inc. assumes no
responsibility resulting from the use or handling of this compound.
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