SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 14/JUN/2005
Date Updated: 14/MAR/2004
Version 1.6
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name 2,4-DINITROPHENYLHYDRAZINE, REAGENT
GRADE, 97%
Product Number D199303
Company Sigma-Aldrich Pty. Ltd.
12 Anella Avenue
Castle Hill NSW 2154
Australia
Technical Phone # +61 2 9841 0555 (1800 800 097)
Fax +61 2 9841 0500 (1800 800 096)
Emergency Phone # +44 8701906777 (1800 448 465)
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
2,4-DINITROPHENYLHYDRAZINE, 119-26-6 204-309-3 None
MOISTENED
Formula C6H6N4O4
Molecular Weight 198.14 AMU
Synonyms 2,4-Dinitrofenylhydrazin (Czech) *
2,4-Dinitrophenylhydrazine * 2,4-Dnph
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Explosive when dry. Highly flammable. Harmful if swallowed.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
EXPLOSION DATA
Sensitivity to Mechanical Impact: May be shock-sensitive if dry.
Dust Potential: This material, like most materials in powder
form, is capable of creating a dust explosion.
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Flammable solid. Emits toxic fumes under
fire conditions.
Explosion Hazards: Dry material is an explosive.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area. Shut off all sources of ignition. Use nonsparking
tools.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Avoid raising dust. Sweep up, place in a bag and hold for waste
disposal. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Avoid contact with eyes, skin, and
clothing. Avoid breathing dust. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep container closed. Keep away from
heat, sparks, and open flame.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Use nonsparking tools. Mechanical
exhaust required.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
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9 - Physical and Chemical Properties
Appearance Physical State: Solid
Color: Red
Form: Powder
Property Value At Temperature or Pressure
pH N/A
BP/BP Range N/A
MP/MP Range 200 - 202 癈
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density N/A
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility Solvent: 10 mg/ml H2SO4 50% complete and
clear
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Conditions to Avoid: May be shock-sensitive if dry.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Nitrogen oxides.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: MV3325000
ACUTE TOXICITY
LD50
Oral
Rat
500 mg/kg
LD50
Intraperitoneal
Mouse
450 MG/KG
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IRRITATION DATA
Eyes
Rabbit
500 mg
24H
Remarks: Mild irritation effect
SIGNS AND SYMPTOMS OF EXPOSURE
Absorption into the body leads to the formation of methemoglobin
which in sufficient concentration causes cyanosis. Onset may be
delayed 2 to 4 hours or longer.
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: Material may be irritating to mucous membranes and
upper respiratory tract. May be harmful if inhaled.
Ingestion: Harmful if swallowed.
TARGET ORGAN INFORMATION
Blood.
CHRONIC EXPOSURE - MUTAGEN
Rat
50 MG/L
Cell Type: liver
Unscheduled DNA synthesis
Mouse
1900 UMOL/KG
Intraperitoneal
DNA damage
ZPOS
Histidine reversion (Ames)
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Burn in a chemical incinerator equipped with an
afterburner and scrubber but exert extra care in igniting as this
material is highly flammable. Observe all federal, state, and
local environmental regulations.
14 - Transport Information
RID/ADR
UN#: 1325
Class: 4.1
PG: II
Proper Shipping Name: Flammable solid, organic, n.o.s.
IMDG
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UN#: 1325
Class: 4.1
PG: II
Proper Shipping Name: FLAMMABLE SOLID, ORGANIC, N.O.S.
Marine Pollutant: No
Severe Marine Pollutant: No
Technical Name: Required
IATA
UN#: 1325
Class: 4.1
PG: II
Proper Shipping Name: Flammable solid, organic, n.o.s.
Inhalation Packing Group I: No
Technical Name: Required
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
INDICATION OF DANGER: Xn F
Harmful. Highly Flammable.
R-PHRASES: 1 11 22
Explosive when dry. Highly flammable. Harmful if swallowed.
S-PHRASES: 35
This material and its container must be disposed of in a safe
way.
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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