SILVER FERN CHEMICAL
Material Safety Data Sheet
GLYCOL ETHER DB
SECTION 1: IDENTIFICATION
Product Name: GLYCOL ETHER DB
Chemical Family: Glycol Ethers
CAS Number: 112-34-5
Chemical Name: 2-(2-Butoxyethoxy) ethanol
Synonyms: diethylene glycol monobutyl ether; butoxyethoxy ethanol; butyl carbitol
Company Business Contact
Silver Fern Chemical, Inc. Customer Service: 206-282-3376
2226 Queen Anne Avenue North info@silverfernchemical.com
Suite #C
Seattle WA 98109, USA
24 Hour Emergency Contact
Infotrac 800-535-5053
Outside USA & Canada 352-323-3500
SECTION 2: HAZARD IDENTIFICATION
Emergency Overview
This material is HAZARDOUS by OSHA Hazard Communication definition.
Signal Word
WARNING.
Hazards
May cause irritation to skin, eyes, and respiratory tract. May cause liver and/or kidney damage. Inhalation of vapors may
cause central nervous system depression. May cause blood abnormalities.
HMIS (U.S.A.):
Health Hazard: 1
Fire Hazard: 1
Reactivity: 0
Personal Protection: E
National Fire Protection Association (U.S.A.):
Health: 1
Flammability: 1
Reactivity: 0
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SILVER FERN CHEMICAL
Material Safety Data Sheet
GLYCOL ETHER DB
Physical State
Liquid.
Color
Clear
Odor
Faint butyl odor
Odor Threshold
No value available.
Potential Health Effects
Routes of Exposure
Eye. Inhalation. Skin. Ingestion.
Signs and Symptoms of Acute Exposure
See component summary.
Diethylene glycol monobutyl ether 112-34-5
Moderate eye irritant. Effects of eye irritation are reversible. Contact may cause mild skin irritation. Not expected to be
a sensitizer. Not a skin absorption hazard.
2-Butoxyethanol 111-76-2
May be irritating to the eyes, skin, and respiratory system. Exposure could cause central nervous system depression
and liver and kidney damage. Severe over-exposure may cause red blood cell damage.
Skin
May cause slight irritation if left in contact with skin.
Inhalation
Vapors or mists from this material can irritate the nose, throat and lungs, and cause signs and symptoms of central
nervous system (CNS) depression, depending on the concentration and duration of exposure.
Eye
Causes noticeable pain, severe irriation and transient corneal injury.
Ingestion
May cause CNS depression, gastrointestinal tract, liver and kidney damage.
Chronic Health Effects
See component summary.
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SILVER FERN CHEMICAL
Material Safety Data Sheet
GLYCOL ETHER DB
Diethylene glycol monobutyl ether 112-34-5
May cause dermatitis by defatting the skin from prolonged or repeated contact.
2-Butoxyethanol 111-76-2
May cause dermatitis by defatting the skin from prolonged or repeated contact. This substance may have effects on
the haematopoietic system, resulting in blood disorders. Animal carcinogen.
Conditions Aggravated by Exposure
Any pre-existing disorders or diseases of the: central nervous system (CNS) skin eyes liver kidney and/or blood
SECTION 3: COMPOSITION / INFORMATION ON INGREDIENTS
Component Name CAS # EU Inventory Concentration Wt.%
Diethylene glycol monobutyl ether 112-34-5 203-961-6 98.0 - 99.5
2-Butoxyethanol 111-76-2 203-905-0 <= 1.0
Compositions given are typical values not specifications.
SECTION 4: FIRST AID MEASURES
General
Take proper precautions to ensure your own health and safety before attempting rescue and providing first aid. For
specific information refer to the Emergency Overview in Section 2 of this MSDS.
Skin
Immediately remove excess chemical and contaminated clothing; thoroughly wash contaminated skin with mild soap
and
water. If irritation persists after washing, seek medical attention. Thoroughly clean contaminated clothing before reuse;
discard contaminated leather goods (gloves, shoes, belts, wallets, etc.).
Inhalation
If symptoms are experienced, move victim to fresh air. Seek medical attention if discomfort persists.
Eye
Thoroughly flush the eyes with large amounts of clean low-pressure water for at least 15 minutes, occasionally lifting
the
upper and lower eyelids. If irritation persists, seek medical attention.
Ingestion
If product is ingested, do not induce vomiting and contact a physican or Poison Control Center.
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SILVER FERN CHEMICAL
Material Safety Data Sheet
GLYCOL ETHER DB
SECTION 5: FIRE FIGHTING MEASURES
Flammable Properties
Classification
OSHA/NFPA Class IIIB combustible liquid.
Flash Point
106 ?(222.8 ?closed cup
C F)
Auto-Ignition Temperature
228 ?(442.4 ?br>
C F)
Lower Flammable Limit
0.85 vol%
Upper Flammable Limit
24.6 vol%
Extinguishing Media
Suitable:
SMALL FIRE: Use dry chemicals, CO2, water spray or alcohol-resistant foam LARGE FIRE: Use water spray, water
fog or alcohol-resistant foam
Protection of Firefighters
Protective Equipment/Clothing:
Wear an approved positive pressure self-contained breathing apparatus and firefighter turnout gear.
Fire Fighting Guidance:
Fight fire from maximum distance or use unmanned hose holders or monitor nozzles. Do not get water inside
containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of
rising sound from venting safety devices or discoloration of tank. Always stay away from tanks engulfed in fire.
Hazardous Combustion Products:
Carbon oxides (CO, CO2)
SECTION 6: ACCIDENTAL RELEASE MEASURES
Release Response
Contain spill with dike to prevent entry into sewers or waterways. For large spills, dike and pump into properly labeled
containers for reclamation or disposal. For small spills, soak up with absorbent material and place in properly labeled
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SILVER FERN CHEMICAL
Material Safety Data Sheet
GLYCOL ETHER DB
containers for disposal. All recovered material should be packaged, labeled, transported and disposed of or reclaimed
in conformance with applicable laws and regulations and in conformance with good engineering practices. Reclaim
where possible.
SECTION 7: HANDLING AND STORAGE
Handling
Do not handle near heat, sparks, or flame. Avoid contact with incompatible agents. Use only with adequate
ventilation/personal protection. Avoid contact with eyes, skin and clothing. Do not enter storage area unless
adequately ventilated. Metal containers involved in the transfer of this material should be grounded and bonded. It is
recommended that any liquid product exposed to air not be highly concentrated by evaporation without first assuring
that no peroxide is present. Alternately, positive steps should be taken to reduce any accumulated peroxides to a safe
level before concentrating the liquid.
Storage
Store containers in a cool, dry, ventilated, fire resistant area away from sources of ignition and incompatible materials.
Keep container tightly closed and properly labeled.
SECTION 8: EXPOSURE CONTROLS AND PERSONAL PROTECTION
Engineering Controls
Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. Emergency shower and eyewash facility should be in close proximity (ANSI Z358.1)
Personal Protection
Inhalation
A respiratory protection program that meets OSHA's 29 CFR 1910.134 or ANSI Z88.2 requirements must be followed
whenever workplace conditions warrant respirator use.
Skin
Wear chemical resistant gloves such as: Rubber PVC
Eye
Wear safety glasses as minimum eye protection. Conditions may warrant the use of chemical goggles and possibly a
face shield. Consult your standard operating procedure or safety professional for advice. Use protective eye and face
devices that comply with ANSI Z87.1-1987.
Additional Remarks
Selection of appropriate personal protective equipment should be based on an evaluation of the performance
characteristics of the protective equipment relative to the task(s) to be performed, conditions present, duration of use,
and the hazards and/or potential hazards that may be encountered during use.
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Material Safety Data Sheet
GLYCOL ETHER DB
Occupational Exposure Limits:
Component Name Source Type Value Notation
2-Butoxyethanol US (ACGIH) TWA 20 ppm None.
US (OSHA) TWA 50 ppm Skin.
240 mg/m3
SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES
Appearance: Liquid. Clear
Odor: Faint butyl odor
Odor Threshold: No value available.
pH: 6 - 7.5
Boiling Point/Boiling Range: 230 ?(446 ?@ 760 mm Hg
C F)
Freezing Point/Melting Point: -68 ?(-90.4 ?br>
C F)
Flash Point: 106 ?(222.8 ?closed cup
C F)
Auto-ignition: 228 ?(442.4 ?br>
C F)
Flammability: OSHA/NFPA Class IIIB combustible liquid.
Lower Flammable Limit: 0.85 vol%
Upper Flammable Limit: 24.6 vol%
Explosive Properties: No Data Available.
Oxidizing Properties: No Data Available.
Vapor Pressure: 0.06 mm Hg @ 20 ?(68 ?br>
C F)
Evaporation Rate: 0.01 (butyl acetate = 1)
Relative Density: 0.95 @ 20 ?(68 ?br>
C F)
Relative Vapor Density: 5.6 (Air = 1.0)
Viscosity: 6.5 mPa.s
Solubility (Water): Complete
Partition Coefficient (Kow): Log Kow = 0.5 Estimated
Additional Physical and Chemical Properties: No additional information available.
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Material Safety Data Sheet
GLYCOL ETHER DB
SECTION 10: STABILITY AND REACTIVITY
Chemical Stability
The product is stable.
Conditions to Avoid
Avoid contact with strong oxidizers, excessive heat, sparks or open flame.
Substances to Avoid
Oxidizers, Acids, Alkalis
Decomposition Products
Carbon Monoxide and Carbon dioxide.
Hazardous Polymerization
Will not occur.
Reactions with Air and Water
Does not react with water or common materials. May form peroxides in the presence of air.
SECTION 11: TOXICOLOGICAL INFORMATION
PRODUCT INFORMATION
Product Summary
See component summary.
COMPONENT INFORMATION
Diethylene glycol monobutyl ether 112-34-5
Acute Toxicity - Lethal Doses
LD50 (Oral) Rat 5080 MG/KG Mouse 2406 MG/KG
LD50 (Skin) Rabbit 2764 MG/KG
Irritation
Skin
This substance is a mild skin irritant.
Eye
Moderate eye irritant.
Target Organ Effects
Eye.
Reproductive Effects
In vivo animal studies show no adverse reproductive efects.
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Material Safety Data Sheet
GLYCOL ETHER DB
Developmental Effects
Results from animal studies demonstrate that this material is not a teratogen or toxic to the developing embyro or
fetus.
Genetic Toxicity
Negative for genotoxicity both in vitro and in vivo tests.
Carcinogenicity
Not listed by IARC, NTP, OSHA or EPA.
2-Butoxyethanol 111-76-2
Acute Toxicity - Lethal Doses
LC50 (Inhl) Rat ~ 450 PPM 4 HOURS
LD50 (Oral) Rat 530 - 3000 MG/KG BWT Rabbit. 320 - 370 MG/KG BWT
LD50 (Skin) Rabbit. 612 MG/KG BWT
Acute Toxicity - Effects
Inhalation
Exposure to vapor may cause irritation of the eyes, nose, and respiratory tract. May cause nausea. May cause
headaches. Severe over-exposure or prolonged contact may cause red blood cell damage with weakness, confusion,
anxiety, decreased blood pressure, and CNS depression with collapse and coma. Causes rapid damage to red blood
cells and subsequent anemia. Repeated exposure may cause liver and kidney damage.
Ingestion
Ingestion may cause weakness, confusion, anxiety, decreased blood pressure, and CNS depression with collapse and
coma. Causes rapid damage to red blood cells and subsequent anemia. Repeated exposure may cause liver and
kidney damage.
Skin Contact
Moderate hazard by skin contact with liquid or vapor. May be absorbed through the skin and produce toxic effects such
as CNS depression. High dermal doses (most likely achieved from exposure to undiluted liquid) may cause red blood
cell damage with weakness, headache and nausea. Severe over-exposure or prolonged contact may cause red blood
cell damage with weakness, confusion, anxiety, decreased blood pressure, and CNS depression with collapse and
coma. Causes rapid damage to red blood cells and subsequent anemia. Repeated exposure may cause liver and
kidney damage.
Irritation
Skin
Repeated or prolonged contact may cause skin irritation.
Eye
Moderate to severe eye irritant.
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SILVER FERN CHEMICAL
Material Safety Data Sheet
GLYCOL ETHER DB
Sensitization
Not expected to cause sensitization by skin contact.
Target Organ Effects
Damages blood. Damages the lung. Damages the liver. Damages the kidney. Skin irritant. Eye irritant.
Repeated Dose Toxicity
Repeated exposure to EGBE at 125 ppm by inhalation caused injury to red blood cells with subsequent anemia and
changes to the spleen, liver, and kidney. Inhalation exposure to EGBE at or above 32 ppm caused degeneration of the
nasal epithelium. Repeated oral administration of EGBE at doses of 222 mg/kg bwt, caused injury to red blood cells
with subsequent anemia and changes to the spleen, liver, and kidney. Repeated dermal exposure to EGBE at 180
mg/kg bwt caused injury to red blood cells. Moderate risk to health after prolonged exposure.
Reproductive Effects
No adverse effect on reproductive performance was observed in male and female mice exposed to EGBE in drinking
water at a 700 mg/kg bwt/day over two generations. A slight reduction in pup body weights and decreased maternal
water consumption was observed in mice exposed to 700 mg/kg bwt/day EGBE. Dose levels of 1300 mg/kg/day and
higher caused significant parental toxicity (including mortality) and a decreased number of litters.
Developmental Effects
EGBE is not teratogenic in rats or rabbits exposed by inhalation during organogenesis at concentrations up to 200
ppm. Maternal toxicity and minimal fetotoxicity occurred at or above 100 ppm. No maternal or developmental toxicity
was observed in rabbits that received approximately 2100 mg/kg bwt/day EGBE by the dermal route of exposure
during organogenesis.
Genetic Toxicity
No evidence of mutagenic activity in standard bacterial and mammalian test systems in vitro. No increase in
micronuclei in rodents after in vivo exposure.
Carcinogenicity
Long-term exposure via inhalation at concentrations up to 125 ppm caused an increase in the incidence of liver tumors
in male mice and forestomach tumors in female mice. A slight increase in adrenal tumors was observed in female rats.
The NTP has determined that EGBE displays some evidence of carcinogenicity in mice, and equivocal evidence of
carcinogenicity in female rats. The International Agency for Research on Cancer (IARC) has evaluated this material as
an IARC Group 3 not classifiable as to carcinogenicity in humans, based on limited data in animals and inadequate
data in humans.
SECTION 12: ECOLOGICAL INFORMATION
PRODUCT INFORMATION
Ecotoxicity
There is very limited information available on this material. This material, and structurally similar materials, have
exhibited low toxicity in aquatic organisms. The odor and flavor of this material may attract some wildlife and cause
them to consume spilled material.
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SILVER FERN CHEMICAL
Material Safety Data Sheet
GLYCOL ETHER DB
Environmental Fate and Pathway
This material should biodegrade after an acclimation period, and it is is not expected to be environmentally persistant.
Due care should be taken to avoid accidental releases to aquatic or terrestrial systems.
Persistance and Degradability
Bioaccumulation: This material is highly soluble in water and should not bioaccumulate in aquatic or terrestrial
organisms.
COMPONENT INFORMATION
Diethylene glycol monobutyl ether 112-34-5
Ecotoxicity
Acute toxicity to fish
LC50 / 96 HOUR silverside minnow. 2,000 mg/l
LC50 / 96 HOUR bluegill. 1,300 mg/l
Summary: This material is not harmful or toxic to fish.
Acute toxicity to aquatic invertebrates
Summary: No Data Available.
Toxicity to aquatic plants
Summary: No Data Available.
Environmental Fate and Pathway
Expected to have high mobility in soils. It is water soluble and is expected to have low volatility. This material is
expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase is degraded in the atmosphere by
reaction with photochemically produced hydroxyl radicals. Hydrolysis is not expected to be an important factor in the
environmental fate process for this material.
Persistance and Degradability
Stability in Soil: The Koc value suggests that this compound would be highly mobile if released onto soil and would not
adsorb to suspended solids or sediments.
Biodegradation: This material is expected to be readily biodegradable.
Bioaccumulation: 2.0 BCF < 5 This material is not expected to bioaccumulate.
2-Butoxyethanol 111-76-2
Ecotoxicity
Acute toxicity to fish
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Material Safety Data Sheet
GLYCOL ETHER DB
LC50 / 96 HOURS bluegill. 1,490 mg/l
LC50 / 96 HOURS fathead minnow 2,137 mg/l
LC50 / 24 HOURS goldfish 1,650 mg/l
Summary: This material is not harmful or toxic to fish.
Acute toxicity to aquatic invertebrates
LC50 / 48 HOURS Brown shrimp 775 mg/l
LC50 / 48 HOURS waterflea. 835 mg/l
Summary: This material is not harmful or toxic to aquatic invertebrates.
Toxicity to aquatic plants
EC0 / 192 HOURS blue green algae. 35 mg/l
LOEC / 168 HOURS green algae. 900 mg/l
LOEC / 168 HOURS green algae (Selenastrum). 250 mg/l
Summary: This material is harmful to algae or higher aquatic plants.
Toxicity to microorganisms
EC0 / 16 HOURS bacteria. 700 mg/l
Summary: This material is not toxic or harmful to bacteria.
Chronic toxicity to fish
LC50 / 7 d guppy. 983 mg/l
Chronic toxicity to aquatic invertebrates
Summary: No Data Available.
Environmental Fate and Pathway
In air, the estimated photodegradation half-life of EGBE ranges from 16 to 27.5 hours. Does not undergo hydrolysis.
Mobility
Transport between environmental compartments: Highly mobile in soil and likely to volatilize from moist or dry soil
surfaces. Expected to volatilize from surface waters and not likely to adsorb to suspended solids and sediment in
water.
Persistance and Degradability
Stability in Water: In water, the volatilization half-life of EGBE from a model river and lake is estimated to be 25 days
and 185 days, respectively. The estimated half-life in groundwater ranging from 14 days to 8 weeks.
Stability in Soil: In soil, the estimated half-life of EGBE ranges from 7 days to 4 weeks.
Biodegradation: This material is expected to be readily biodegradable.
Bioaccumulation: Low potential for bioaccumulation. BCF = 3.0 (estimated).
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Material Safety Data Sheet
GLYCOL ETHER DB
SECTION 13: DISPOSAL CONSIDERATIONS
Dispose of all waste and contaminated equipment in accordance with all applicable federal, state and local health and
environmental regulations. Recovery and reuse, rather than disposal, should be the ultimate goal of handling efforts.
The materials resulting from clean-up operations may be hazardous wastes and therefore, subject to specific
regulations.
SECTION 14: TRANSPORT INFORMATION
Special Requirements
If you reformulate or further process this material, you should consider re-evaluation of the regulatory status of the
components listed in the composition section of this sheet, based on final composition of your product.
Proper Shipping Name GLYCOL ETHERS, NOT ELSEWHERE CLASSIFIED, NOT REGULATED (DIETHYLENE
GLYCOL MONOBUTYL ETHER)
This information is not intended to convey all specific regulatory or operational requirements/information relating to this
product. It is the responsibility of the transporting organization to follow all applicable laws, regulations and rules relating
to the transportation of the material.
SECTION 15: REGULATORY INFORMATION
Regulatory Status:
Country Inventory
Australia AICS
Canada DSL
China IECS
European Union EINECS
Japan ENCS
Korea ECL
Philippines PICCS
United States TSCA
If identified components of this product are listed under the TSCA 12(b) Export Notification rule, they will be listed
below.
SARA 302/304
This product contains no known chemicals regulated under SARA 302/304.
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Material Safety Data Sheet
GLYCOL ETHER DB
SARA 311/312
Based upon available information, this material is classified as the following health and/or physical hazards according
to Section 311 & 312:
Immediate (Acute) Health Hazard.
Delayed (Chronic) Health Hazard.
SARA 313
This product contains no known chemicals regulated under SARA 313.
State Reporting
This product contains no known chemicals regulated by California's Proposition 65.
This product contains the following chemicals regulated by New Jersey's Worker and Community Right to Know Act:
2-Butoxyethanol 111-76-2
This product contains the following chemicals regulated by Massachusetts' Right to Know Law:
2-Butoxyethanol 111-76-2
This product contains the following chemicals regulated by Pennsylania's Right to Know Act:
2-Butoxyethanol 111-76-2
SECTION 16: OTHER INFORMATION
Date Created: 2/29/2008
Date Last Updated: 2/29/2008
DISCLAIMER OF RESPONSIBILITY
The information on this MSDS was obtained from sources which we believe are reliable. However, the information is
provided without any warranty, expressed or implied, regarding its correctness. Some information presented and
conclusions drawn herein are from sources other than direct test data on the substance itself. The conditions or
methods of handling, storage, use and disposal of the product are beyond our control and may be beyond our
knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss,
damage, or expense arising out of or in any way connected with handling, storage, use, or disposal of this product. If
the product is used as a component in another product, this MSDS information may not be applicable.
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