MATERIAL SAFETY DATA SHEET 1,1,2,2-TETRACHLOROETHANE
PRODUCT CODE NUMBER(S): 9000-1
PRODUCT IDENTIFICATION vents and carbon monoxide) may be released by decompo-
sition.
Chemical Name and Synonyms:
1,1,2,2-Tetrachloroethane; Acetylene tetrachloride FIRE AND EXPLOSION DATA
Chemical Family: Halogenated aliphatic hydrocarbon
Flammability: Will not burn, but can decompose at ele-
Chemical Formula: CHCl2CHCl2
vated temperatures to form toxic hydrogen chloride and
Product Use: Laboratory solvent phosgene gases. Vapours are heavier than air and can col-
Manufacturer's Name and Address: lect in low-lying areas, creating a toxicity hazard.
Caledon Laboratories Ltd. Extinguishing Media: Use extinguishing media suitable for
surrounding fire. Use water spray or fog to cool containers,
40 Armstrong Avenue
disperse vapours, and flush spills away from fire area. Fight
Georgetown, Ontario L7G 4R9
fire from upwind, from a safe distance. Firefighters must
Telephone No: (905) 877-0101
wear NIOSH approved full-body encapsulating chemical re-
Fax No: (905) 877-6666 sistant suit and full face-piece, positive-pressure
self-contained breathing apparatus. Closed containers may
Emergency Telephone No: CANUTEC (613) 996-6666
explode in heat of fire; withdraw immediately in case of ris-
HAZARDOUS INGREDIENTS OF MATERIALS ing sound from venting device, or discolouration in container.
Flash Point (Method Used): Not applicable
Ingredients % TLV Units CAS No. Autoignition Temperature: Not applicable
Upper Flammable Limit (% by volume): Not applicable
1,1,2,2-Tetra- >98 1 ppm 79-34-5
chloroethane Lower Flammable Limit (% by volume): Not applicable
Hazardous Combustion Products: COx, hydrogen chlo-
PHYSICAL DATA ride gas, phosgene
Sensitivity to Impact: None identified
Physical State: Liquid
Sensitivity to Static discharge: None identified
Odour and Appearance: Clear, colourless to pale yellow
liquid with a chloroform-like suffocating odour
TOXICOLOGICAL PROPERTIES AND HEALTH DATA
Odour Threshold (ppm): 3 ppm (poor warning properties,
detectable level higher than TLV)
Toxicological Data:
Vapour Pressure (mm Hg): 5 mm Hg at 20癈
LD50 (oral, rat) 250 mg/kg; (dermal, rabbit) 6,380 mg/kg
Vapour Density (Air = 1): 5.79
LC50: (mouse) 4,500 mg/m3/2h
Evaporation Rate (Butyl acetate=1): 0.65
Boiling Point (癈): 146癈
Effects of Acute Exposure to Product:
Freezing Point (癈): -36癈
Very toxic by all routes of exposure. May be fatal by inhala-
pH: Not applicable
tion, skin absorption or ingestion.
Specific Gravity: 1.596
Inhaled: Very toxic. Can cause headache, dizziness,
Coefficient of Water/Oil distribution: LogP (oct)= 2.39
coughing, wheezing, nausea, vomiting, weight loss, abdomi-
nal pain, liver damage, peripheral neuritis with loss of feeling
SHIPPING DESCRIPTION in the extremities, tremors, muscle weakness, narcosis,
CNS depression with convulsions, coma and death. Inhala-
UN: 1702
tion can also cause pulmonary edema which may be fatal.
T.D.G. Class: 6.1
Symptoms (shortness of breath, cyanosis) may not appear
Pkg. Group: II until several hours after exposure.
In contact with skin: Causes irritation and inflammation.
REACTIVITY DATA Readily absorbed by skin with systemic effects as in
"Inhaled".
Chemical Stability: Stable; breaks down slowly in the
In contact with eyes: Lacrymator; will cause irritation,
presence of moisture, air or sunlight.
tearing and inflammation. No reported eye injuries due to in-
Incompatibility with other substances: Reacts explo-
dustrial exposure. Animal testing showed irritation but no
sively with strong oxidizing agents, strong bases. Reacts
corneal injury from high vapour exposure.
violently or explosively with chemically active metals (Na, K)
Ingested: May cause excess salivation, nausea, vomiting,
or strong caustics, nitrates, 2,4-dinitrophenyl disulphide. In
diarrhea, headache, dizziness, abdominal pain, liver dam-
presence of steam, contact with hot iron, aluminum or zinc
age with jaundice, narcosis, convulsions, coma and death.
may cause formation of toxic vapours. Hydrolizes on con-
Doses as small as 5 mL can cause death.
tact with water resulting in highly toxic fumes. In the
presence of moisture, may be corrosive to non-ferrous met-
Effects of Chronic Exposure to Product:
als, and mild steel.
Reactivity: Avoid high temperatures, incompatible materi- Causes damage to liver, kidneys, heart and lungs. Jaundice
als, generatian of mist, exposure to moisture, light and air. may occur. May cause blood effects (increased number of
Hazardous Decomposition Products: Toxic vapours or white cells) and peripheral neurological disturbances, with
gases (phosgenes, hydrogen chloride gas, chlorinated sol-
MSDS 1,1,2,2-TETRACHLOROETHANE
CODE: 9000-1
loss of feeling and tingling or pain in the extremities, muscle material to the original containers. Treat empty containers with
caution as they contain hazardous residues.
weakness and difficulty in walking.
Storage Requirements: Solvents should not be stored in base-
Carcinogenicity: Test results inconclusive. Inadequate evi-
ment premises (risk of accumulation of heavy solvent vapour).
dence for classification as human carcinogen. IARC - not
Do not use containers of aluminum or its alloys for storage. Store
classifiable as human carcinogen (Group 3); Not listed in
in suitable, labelled containers, in a cool, dry, well-ventilated
NTP report on carcinogens. ACGIH - A3, confirmed animal
place, out of direct sunlight, and away from ignition sources and
carcinogen, relevance to humans unknown (RTECS No. KI
incompatible materials. Keep air out of container. Keep con-
8575000).
tainer tightly closed when not in use and when empty. Protect
Teratogenicity: Caused teratogenic effects in some animal
from damage, and inspect frequently for signs of leaking. Stor-
testing. No human information available.
age facilities should have raised sills or ramps, with trenching to a
Reproductive Effects: No human information available.
safe area.
Some effects in tests with rats.
Mutagenicity: Negative in tests with animals and isolated
FIRST AID MEASURES
mammalian cells; slightly mutagenic in bacterial tests.
Synergistic Products: Alcohol or other substances capa- Specific Measures:
ble of stimulating liver enzyme activity may increase the
Eyes: IMMEDIATELY flush eyes with gently running water for
toxicity of TCE.
ten to fifteen (10-15) minutes holding eyelids open while flushing.
PREVENTIVE MEASURES Take care not to flush contaminated water into unaffected eye.
Wear protective gloves to avoid contact. Get medical attention
Engineering Controls: Non-sparking, grounded exhaust immediately.
ventilation, separate from other ventilation systems. Skin: Remove contaminated clothing (including rings, watches,
Respiratory Protection: Dust/mist mask. Fumehood. For belts, and shoes) under running water. Wear protective clothing
concentrations above the TLV, any detectable or unknown and gloves to avoid contact during first aid procedures. IMMEDI-
concentrations, for tank or confined space entry, for fire or ATELY flush exposed area with large amounts of warm running
spill conditions, NIOSH approved full face-piece, posi- water for at least twenty (20) minutes. GET MEDICAL ATTEN-
tive-pressure self-contained breathing apparatus, or TION IMMEDIATELY. If breathing is difficult or absent, follow
positive-pressure full face-piece supplied-air respirator with measures in "Inhalation". Decontaminate clothing before reuse,
auxillairy positive-pressure self-contained breathing appara- or discard.
tus. Inhalation: Remove to fresh air (caution must be used by rescu-
Eye Protection: Chemical safety goggles and/or face ers to avoid exposure to contaminating fumes). Give oxygen for
shield. breathing difficulty. Give artificial respiration if breathing has
stopped; use mouth guard to avoid possible contact with
Skin Protection: PolyVinyl alcohol, Viton?
chemical. If breathing AND pulse are absent give CPR. GET
Tychem訠R/LV, Tychem訲K gloves. Impermeable cover-
MEDICAL ATTENTION IMMEDIATELY. Stay with casualty until
all, boots or other protective clothing sufficient to prevent
medical assistance is reached.
contact.
Ingestion: DO NOT INDUCE VOMITING. DANGER OF ASPI-
Other Personal Protective Equipment: Safety shower
RATION WITH VOMITING. If casualty is alert and not
and eye wash in work area.
convulsing, rinse out mouth with water. Give 2 to 4 glasses of
Leak and Spill Procedure: Restrict access to area of spill.
water to dilute material. GET MEDICAL ATTENTION IMMEDI-
Ventilate area. Eliminate all sources of ignition. Cleanup
ATELY. If spontaneous vomiting occurs, have casualty lean
personnel must be thoroughly trained in the hazards of the
forward with head down to avoid breathing in of vomitus. If
product and must wear protective equipment and clothing
breathing is difficult or absent, follow measures in "Inhalation".
sufficient to prevent inhalation of mists or vapours and con-
tact with skin and eyes. DO NOT TOUCH SPILLED
REFERENCES USED
MATERIAL. Dike spills. Prevent from entering sewers or
waterways. Collect on inert absorbent material and transfer CCINFO disc: Cheminfo
to suitable, labelled, covered containers for recovery or dis-
Budavari: The Merck Index, 12th ed., 1997
posal. Contaminated material may pose the same hazards
Royal Society of Chemistry: Chemcial Safety Data Sheets, Vol. 1,
as the chemical; treat with caution. Flush area of spill with
1992
copious amounts of running water.
Waste Disposal: Follow all federal, provincial and local Sax, Lewis: Hawley's Condensed Chemical Dictionary, 11th ed.,
regulations for disposal. 1987
Handling Procedures and Equipment: VERY TOXIC. Suppliers' Material Safety Data Sheets
SKIN/EYE IRRITANT, POSSIBLE MUTAGEN, REPRODUC-
TIVE HAZARD, AND CARCINOGEN. Workers handling this
ADDITIONAL INFORMATION
material must be thoroughly trained in its hazards and its
safe use. Do not work alone with this chemical. The user is Date Issued: April 14, 1989
responsible for wearing appropriate protective equipment Revision: February 2008
and clothing depending on the application. Avoid all con-
MSDS: 9000-1
tact with skin and eyes and any inhalation of vapours.
Proposed WHMIS Designation: D1B; D2A
Keep away from heat and ignition sources. Avoid generat-
ing mists or vapours. Concentrated vapours are heavier
than air and will collect in low areas such as pits and other Prepared by: Caledon Laboratories Ltd. (905) 877-0101
confined areas. Do not enter these areas where vapour of Caledon Laboratories Ltd. believes the information contained
this product is suspected unless special breathing apparatus herein is reliable and accurate. Caledon makes no warranty with re-
is used. Use the smallest amount possible for the purpose
spect thereto and expressly disclaims all liability for reliance
in a designated area with adequate ventilation. Stand up-
thereon. Such information is solely for your consideration, investi-
wind of operations. Keep work area free of incompatible
gation, and verification.
and extraneous substances. Do not return contaminated
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