MATERIAL SAFETY DATA SHEET
SECTION 1 - IDENTIFICATION OF PRODUCT AND COMPANY
1-866-531-8896
Pfizer Inc Emergency telephone
24 Hours
Pfizer Animal Health Hours of operation
1-800-366-5288
235 East 42nd Street Telephone
New York, NY 10017
Trade names ALBON ?SUSPENSION 5%
Product name ALBON ?(sulfadimethoxine) SUSPENSION 5%
Synonyms Sulfadimethoxine Suspension 5%
Sulfonamide
Chemical family
Antibiotic agent
Therapeutic use
Smooth, uniform yellow suspension with a sweet odor
Description
SECTION 2 - COMPOSITION
Ingredient CAS Number Amount
Sulfadimethoxine* 122-11-2 5.0%
Carbomer 9003-01-4 Proprietary
Citric acid monohydrate* 5949-29-1 Proprietary
FD & C Yellow No. 5 1934-21-0 Proprietary
FD&C yellow No. 6 2783-94-0 Proprietary
Invert sugar 8013-17-0 Proprietary
Flavor Not assigned Proprietary
Methylcellulose 9004-67-5 Proprietary
Pluronic F-68 9003-11-6 Proprietary
Sodium benzoate 532-32-1 Proprietary
Sodium citrate, dihydrate* 6132-04-3 Proprietary
Sodium hydroxide NF* 1310-73-2 Proprietary
Sucrose* 57-50-1 Proprietary
*Hazardous
Note: Ingredient(s) indicated as hazardous have been assessed under US OSHA
Hazard Communication Standard for workplace safety (29 CFR
1910.1200).
SECTION 3 - HAZARDS IDENTIFICATION
Signal word CAUTION!
Statements of hazard MAY CAUSE ALLERGIC REACTION IN INDIVIDUALS
SENSITIVE TO SULFONAMIDES.
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SECTION 3 - HAZARDS IDENTIFICATION ... continued
None known
Eye effects
Skin effects Contact with sulfonamides may cause dermatitis. Allergic skin reaction
may occur based on effects of other sulfonamides.
An Occupational Exposure Limit has been established for one or more of
Inhalation effects
the ingredients (see Section 8). See 'Statements of hazard' and/or 'Other
potential health effects' in this section.
Accidental ingestion may cause effects similar to those seen in clinical use.
Ingestion effects
See 'Statements of hazard' and/or 'Other potential health effects' in this
section.
Individuals sensitive to this material or other materials in its chemical class
Other potential health
effects may develop allergic reactions. As in all sulfonamide therapy, the
following reactions may occur including nausea, vomiting, diarrhea,
inflammation of the liver and pancreas, blood disorder, drug fever, skin
rash, infection of the conjunctiva and sclera, blood in the urine and
crystalluria.
This document has been prepared in accordance with the US OSHA
NOTE:
Hazard Communication Standard, which requires the inclusion of all
known hazards of the product or its ingredients regardless of the potential
risk. The precautionary statements and warnings included may not apply in
all cases. Your needs may vary depending upon the potential for exposure
in your workplace. If your workplace is regulated by OSHA, this
document must be used as a part of a complete hazard-training program.
SECTION 4 - FIRST AID MEASURES
Skin Remove contaminated clothing and shoes. Wash skin with soap and water.
Wash clothing and thoroughly clean shoes before reuse. If irritation occurs
or persists, get medical attention.
Eyes Immediately flush eyes with water for at least 15 minutes. If irritation
occurs or persists, get medical attention.
Inhalation Remove to fresh air. If not breathing, give artificial respiration. Get
medical attention.
Ingestion Get medical attention. Do not induce vomiting unless directed by medical
personnel. Never give anything by mouth to an unconscious person.
SECTION 5 - FIRE FIGHTING MEASURES
Wear approved positive pressure, self-contained breathing apparatus and
Fire fighting instructions
full protective turn out gear. Evacuate area and fight fire from a safe
distance.
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SECTION 5 - FIRE FIGHTING MEASURES ... continued
Water, dry powder or foam extinguishers are recommended.
Extinguishing media
No data available
Flash point
Not known
Hazardous combustion
products
SECTION 6 - ACCIDENTAL RELEASE MEASURES
Review Sections 3, 8 and 12 before proceeding with clean up.
General
Use non-combustible absorbent material to wipe up spill and place in a
Small spill
sealed container for disposal. Clean spill area thoroughly.
Dike, pump, or use non-combustible material to absorb spill; then place in
Large spill
a suitable, labeled recovery container. Close container and move it to a
secure holding area.
SECTION 7 - HANDLING AND STORAGE
General handling Use only in a well-ventilated area. Avoid breathing vapor or mist. Avoid
contact with eyes, skin and clothing.
Store in a cool, dry place.
Storage conditions
Store as directed by product packaging.
Temperature range
for storage
SECTION 8 - EXPOSURE CONTROLS/PERSONAL PROTECTION
Exposure limits
Compound Issuer Type OEL
Sucrose OSHA TWA-8 Hr 5 mg/m?(respirable fraction)
OSHA TWA-8 Hr 15 mg/m?(total dust)
ACGIH TWA-8 Hr 10 mg/m?br>
The exposure limit(s) listed for solid components are only relevant if dust
Exposure information
may be generated.
General room ventilation is adequate unless the process generates dust,
Ventilation
mist or fumes.
Respiratory protection is not expected to be necessary under normal
Respiratory protection
handling conditions; required only if mist is generated.
Wear safety glasses with sideshields if eye contact is possible.
Eye protection
Wear protective clothing with long sleeves to avoid skin contact. Wash
Skin protection
hands and arms thoroughly after handling this mixture.
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SECTION 8 - EXPOSURE CONTROLS/PERSONAL PROTECTION ... continued
Wear protective gloves to avoid routine skin contact.
Hand protection
SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical form Smooth, uniform suspension
Yellow
Color
Sweet
Odor
Mixture
Molecular weight
Mixture
Molecular formula
4.4-4.8
pH
No data available
Boiling point
Not applicable
Melting point
No data available
Density
No data available
Vapor pressure
No data available
Water solubility
No data available
Solvent solubility
1.26-1.28 @ 25癈
Specific gravity
SECTION 10 - STABILITY AND REACTIVITY
Stable
Reactivity
Direct sunlight, conditions that might generate heat and dispersion as a
Conditions to avoid
dust cloud
Strong oxidizers
Incompatibilities
No data available
Hazardous
decomposition
products
Will not occur
Hazardous
polymerization
SECTION 11 - TOXICOLOGY INFORMATION
Toxicology summary There are no data for this formulation. The information included in this
section describes the potential hazards of the active ingredient, except
where noted.
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SECTION 11 - TOXICOLOGY INFORMATION ... continued
Acute toxicity
Compound Type Route Species Dosage
Sulfadimethoxine LD50 Oral Rat >10 g/kg
Sodium benzoate LD50 Oral Mouse 1600 mg/kg
No data available
Eye
Dermatitis may occur from contact of sulfonamides with the skin.
Skin
No data available
Inhalation
See Acute toxicity table
Ingestion
Other sulfonamide drugs which have been evaluated are not mutagenic.
Mutagenicity
Hypersensitivity reactions to sulfonamides have been reported.
Sensitization
In rats, oral dosing of 9,100 mg/kg sulfadimethoxine for 13 weeks caused
Subchronic effects
changes in thyroid weight (goitrogenic effect) and decreased weight gain.
Sulfonamides are known to be goitrogenic, but not in primates or humans.
Dogs given daily oral doses of 160 mg/kg sulfadimethoxine for 13 weeks
showed no signs of toxicity.
Studies to evaluate the carcinogenic potential of sulfadimethoxine were
Chronic effects/
carcinogenicity not available. Other sulfonamide drugs which have been evaluated are not
carcinogenic.
None of the components of this formulation is listed as a carcinogen by
Carcinogen status
IARC, NTP or OSHA.
Not determined
Reproductive effects
In humans, sulfonamides administered prior to delivery can cause jaundice
Teratogenicity
and hemolytic anemia in the offspring. Studies in pregnant laboratory
animals administered sulfadimethoxine have shown developmental effects,
but retrospective studies in humans with other sulfonamides have not been
conclusive.
Like other sulfonamides, this material might produce hypersensitivity
At increased risk from
reactions in some individuals.
exposure
SECTION 12 - ECOLOGICAL INFORMATION
The environmental characteristics of this material have not been fully
Environmental overview
evaluated. Releases to the environment should be avoided.
SECTION 13 - DISPOSAL INFORMATION
Incineration is the recommended method of disposal for this material.
Disposal procedure
Observe all local and national regulations when disposing of this material.
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SECTION 14 - TRANSPORTATION INFORMATION
Not regulated for transport under USDOT, EUADR, IATA, or IMDG
General shipping
regulations.
instructions
SECTION 15 - REGULATORY INFORMATION
Irritant
EU Classification
EU Labelling Xi
EU Label Pictogram(s)
R43 - May cause sensitization by skin contact.
Risk phrases
S37 - Wear suitable gloves.
Safety phrases
Not listed
TSCA status
No
SARA section 302
No
SARA section 313
Not listed
California Proposition 65
Class D, Division 2, Subdivision B
Canadian WHMIS
SECTION 16 - OTHER
Disclaimer Pfizer Inc believes that the information contained in this Material
Safety Data Sheet is accurate, and while it is provided in good faith, it
is without a warranty of any kind, expressed or implied.
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