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Du Pont Chemicals
I
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ed
2044FR Printed 29-Oct-91
"FREON" TMS Cleaning Agent ~z b3~
MATERIAL
IDENTIFICATION
Corporate Number DU001082
"FREON" a registered trademarkof DuPont.
is
Man
ufacturer/Di'stributor Du Pont
1007 Market Street
Wilmington, DE 19898
Product Information 1-800-441-9450
Phone Numbers .;
Transport Emergency CHEMTREC: 1-800-424-9300
i
Medical Emergency 1-800-441-3637
Chemical Family HALOGENATED HYDROCARBON
Du Pont Registry Number DP10-35-9
Formula CCI2FCCIF2/CH3OH/CH3NO2
Reported/Included
TSCA
Inventory Status
1 -- ~FPA
NPCA-HMIS
Ratings Health:
Flammability: 0 }'1 FR
Reactivity: 1 ~--
PersonalProtection rating to be suppliedby-~e'ser
depending use
on
conditions.
COMPONENTS
Material CAS Number Percent
J
76-13-1 94.10
*ETHANE,1,1,2-TRICHLORO-1,2,2-TRIFLUORO-
("FREON"TF) _t,1/
*METHANOL 67-56-1 5.70
NITROMETHANE 75-52-5 0.20 ;J
/
" Regulated a Toxic
as Chemical Section of Title III of theSuperfund
under 313 Amendments
andReauthodzation 1986
Actof and
40CFR 372.
part
(continued)
Printed Recycled
on Paper
I I II
PHYSICALDATA
Boiling Point 39.6? (104.0癋)
336 mm at 20癈 (68癋)
Hg
Vapor Pressure
2.8 (Air = 1.0) at 25 degC (77 deg
Vapor Density
100 WT %
%Volatiles
Evaporation Rate- Not available
WaterSolubility <0.21 WT %
pH Neutral
Odor Slight ethereal
Form Clearliquid
Color Colorless
Density 1.478- Liquid
i I I
ii
EAC'g'vn'
HAZAmX)US
Instability .~ Material is stable. However,
avoid openflames and high
temperatures.
Incompatibility Incompatible
with alkali or alkaline earth metals-powdered Zn,
AI,
Be, etc.
Polymerization Polymerization
will not occur.
Decomposition : Decompositionproducts are hazardous.
"FREON" TMS can be decomposed by high
temperatures (open flames, glowin metal
9
surfaces,,etc. ) forming hydrochloricand
hydrofluoric acids and possibly carbonyl
halides.
Jl. J
AND EXPLOSION DATA
Flash Point Will not burn
Flammable
Limits in Air, %by VolumeLELNot applicable
UELNot applicalbe
Autoignition Will not burn
Autodecomposition Not determined
Drums mayrupture under fire conditions. Decomposition
may
Fire and Explosion Hazards
occur.
As appropriate for combustibles area.
in
Extinguishing Media
Special Fire Fighting Instructions Usewater spray or fog to cool containers. Self-contained
breathing apparatus(SCBA) required if drumsrupture and
is
contentsare spilled underfire conditions.
(continued)
Page2
2044FR
HEALTH HAZARD OmaA ON
PRINCIPAL HEALTH HAZARDS (Including Significant Routes,
Effects, Symptoms of Overexposure, and Medical Conditions
Aggravated by Exposure)
May be fatal or cause blindness if swallowed. Cannot be
mdd~oTsonDlrs. ~ti-ou of h~gh--concentrat~on~ uf
vapor is harmful and may cause heart irregularities,
unconsciousness, or death. Intentional misuse or deliberate
inhalation may cause death without warning. Vapor reduces
oxygen available for breathing and is heavier than air.
Product causes eye and skin irritation.
ANIMAL DATA:
"FREON" TF
Inhalation 4-hour LC50: 52,500 ppm in rats
43,000 mg/kg in rats
0ral LD50
Skin Absorption ALD : >Ii,000 mg/kg in rabbits
The compound is a mild skin and eye irritant and has
produced weak allergic skin reactions in tests with
laboratory animals. Single, high inhalation exposures to
animals caused anesthetic effects such as tremors,
dizziness, incoordination and loss of consciousness.
I)
Irregular heartbeat (cardiac arrhythmias) due to cardiac
sensitization to adrenalin may occur following high
inhalation overexposure. Repeated inhalation exposures
produced central nervous system effects. 0ral
administration of the liquid near lethal doses produced
lethargy.
There is no evidence of carcinogenicity or teratogenicity in
animal testing. In a reproductive toxicity study in rats,
no adverse effects were seen at concentrations of 500 ppm,
and only minimal effects were observed at 12,500 ppm. This
compound does not produce genetic damage in bacterial or
mammalian cell cultures. It does not produce heritable
genetic damage in male animals.
Methanol
Tnhalation i-hour LC50: 145,000 ppm in rats
0ral LD50 9100 mg/kg in rats
Skin Absorption LD50 : 15,840 mg/kg in rabbits
The compound is a skin and eye irritant. Skin absorption of
significant amounts resulted in death in several animal
species. Toxic effects described in animals from exposures
by ingestion include anesthetic effects, ocular damage,
kidney effects, liver effects and acidosis. Toxic effects
described in animals from exposures by inhalation include
eye irritation and blindness. Tests in bacterial or
mammalian cell cultures demonstrate no mutagenic activity.
Behavorial abnormalities were observed in the offspring of
rats given drinking water containing 2% methyl alcohol.
Developmental effects were observed in the offspring of rats
exposed by inhalation during pregnancy to levels which would
cause maternal effects in humans. It was concluded,
(~nUnu~)
2044FR Page 3
however, that methanol is not a unique hazard for the
conceptus.
Nitromethane
l~h~a~l~t-ion 4~hour ALC: bU~0 ppm in rats
Oral LD50 1210 mg/kg in rats
The compound is not a skin irritant or an eye irritant in
animals. Exposure to vapors causes centralnervous system
effects, eye and respiratory irritation, anesthetic effects,
and nonspecific effects, such as weight loss and irritation.
Ingestion caused liver effects and nonspecific effects such
as weight loss, and irritation. Tests in bacterial or
mammalian cell cultures demonstrate no mutagenic activity.
HUMAN HEALTH EFFECTS:
Human health effects of overexposure to the product by skin
contact may cause skin irritation with discomfort or rash.
Methanol can be absorbed through the skin in toxic amounts.
Eye contact may cause eye irritation with discomfort,
tearing, or blurring of vision. Prolonged contact may cause
drying of skin, a tingling sensation, and numbness.
Overexposure by inhalation or ingestion to the product may
cause temporary nervous system depression with anesthetic
effects such as dizziness, headache, confusion and loss of
consciousness. Higher inhalation exposures may cause
temporary alterations of the heart's electrical activity
with irregular pulse, palpitations or inadequate
circulation. Other effects from inhalation overexposure may
include irritation of the upper respiratory tract, nausea
and weakness. Fatality from gross overexposure to the
product may occur.
The major ingestion hazard from "FREON" ll3 is aspiration
(liquid entering the lung during ingestion or vomiting)
which may result in "chemical pneumonia". Symptoms may
include coughing, gasping, choking, shortness of breath,
bluish discoloration of the skin, rapid respiration and
heart rate, and fever. Pulmonary edema or bleeding,
drowsiness, confusion, coma and seizures may occur in severe
cases. Symptoms may develop immediately or as late as 24
hours after exposure depending on the amount of chemical
aspirated into the lung.
has been
Methanol overexposure associated with abnormal
liver or kidney function as detected by laboratory tests and
acidosis. Inhalation, ingestion or skin absorption of
methanol has also been associated with visual disturbances,
including blindness. A fatal dose of methanol by ingestion
is from 60-250 mL. For "FREON" I13, one report cites two
cases of workers repeatedly exposed and alleging liver
damage. Additional studies of workers exposed for over two
years to concentrations of up to 4700 ppm reported no
adverse effects other than dry skin.
(continued)
2044FR Page 4
?br>
HAZARD INFORMATION (cent~u~
14v-~.LTH
Individuals with preexisting diseases of the cardiovascular
system, central nervous system, retina, liver or kidneys may
have increased susceptibility to the toxicity of excessive
exposures.
C.,arcinogenicity None-of~(he-compon
en ts-inffhis-material-is4isted-by-tARC,
,'/F-P,
OSHA, ACGIH a carcinogen.
or as
# Exposure Limits
"FREON" TMSCleaning Agent
TLV (ACGIH) NoneEstablished
PEL (OSHA) NoneEstablished
Other *SEE ADDITIONAL INFORMATION AND
REFERENCES SECTION FOR A DEFINITION OF
THE "SKIN" NOTATION.
Other Applicable Exposure Limits
ETHANE, 1,1,2-TRICH LORO-1,2,2-TRIFLUORO-
AEL* (Du Pont) NoneEstablished
1,000 ppm, 7,670 rag/m3 - 8 Hr TWA
TLV (ACGIH)
d- STEL1,250ppm, 9,590 mg/m3
1,000 ppm, 7,600 mg/m3 8 Hr TWA
-
PEL (OSHA)
STEL1,250 ppm, 9,500 m~m3
METHANOL
AEL* (0t~ Pont) 200 ppm- 8 & 12 Hr. TWA Skin
-
200 ppm, 262 mg/m3 8 Hr TWA
-
TLV (ACGIH)
STEL 250 ppm,328 rag/m3 - Skin
200 ppm, 260 mg/m3- 8 Hr TWA
PEL (OSHA)
STEL250 ppm, 325 mg/m3- Skin
NITROMETHANE
AEL* (Du Pont) NoneEstablished
100 ppm, 250 mg/m3- 8 Hr TWA
TLV (ACGIH)
SeeNotice of Intended Changes
(1991-92)
20 ppm, 50 mg/m3 8 Hr. TWA
-
PEL (OSHA) 100 ppm, 250 mg/m3- 8 Hr TWA
?AEL DuPont's
is Acceptable
Exposure Where
Umit. governmentally oocupational
imposed exposure
limits which lowerthan
are
theAEL in effect,such
are limitsshalltakeprecedence.
Safety Precautions Donot take internally. Avoidcontact with eyes, skin and
clothing. Wash thoroughly after handling. Usewith
sufficient ventilation tokeepemployee exposurebelow
recommended limits.
FIRST AID
INHALATION
If high concentrations are inhaled, immediately remove to
fresh air. Keep persons calm. If not breathing, give
artificial respiration. If breathing is difficult, give
oxygen. Call a physician.
SKIN CONTACT
In case of skin contact, flush with water after excessive
contact. Get medical attention if irritation is present.
(continued)
2044FR Page5
AID(continued).
EYE CONTACT
In case of eye contact, immediately flush with plenty of
water for 15 minutes. Call a physician.
INGESTION
T~a~lowed, may be~fatal or cause blindness.
Immediately give two glasses of water and induce
vomiting. Call a physician. Never give anything by
mouth to an unconscious person.
Notesto Physician Because possible disturbancesof cardiac rhythm,
of
catecholamine drugs, such as epinephrine, should be
consideredonly as a last resort in life-threatening
emergencies.
For ingestion, dilute 100mLof 100-proofethyl alcohol
(grain alcohol) in 2000mLwater and give 1.5mL/kg of
bodyweight, 100 mLfor an average
or adult, as an antidote.
PROTECTION INF(~RMATION
Generally Applica~le Con~'o{Measuresand Precautions
Good ventilation should be provided to keep concentrations
.; belowthe exposure limit. Mechanical ventilation should be
' usedin low or enclosed places.
Personal Protective Equipment Imperviousgloves and chemical splash gogglesshould be used
whenhandling liquid. Self-containedbreathing apparatus
(SCBA) requiredif a large spill occurs.
is
DISPOSAL INFORMATION
AquaticToxicity "FREON" : 96-hour LC50, fathead minnows: 1250 ppm
TF
96-hour LC50, rainbowtrout : 7.4 mg/L
Methanol : 96-hour LC50, fathead minnows:28.1 g/L
Nitromethane: 96-hour LC50, fathead minnows:<659.2 mg/L
The 48-hour LC50in carp is >40 mg/L
Spill, Leak, or Release NOTE: Review FIRE AND EXPLOSION HAZARDS and SAFETY
PRECAUTIONSbefore proceeding with clean up. Useappropriate
PERSONAL PROTECTIVE EQUIPMENT during clean up.
Ventilate area. Donot flush into sewers.Dikespill.
Collect on absorbent material andtransfer to steel drums
for recoveryor disposal. Comply with Federal, State and
local regulationson reporting releases.
Waste Disposal Complywith Federal, State and local regulations. Remove
to
a permitted wastedisposal facility. EPA Hazardous Waste
Nos. F001and F002mayapply to wastematerials.
(continued)
Page 6
2044FR
SH~P~G ~FORMA~ON
Shipping Containers Tank Car
Tank Truck
Drums
"FREON" TMS CLEANINGAGENTIS NOT REGULATED A
AS
HAZARDOUS
MAT-ERIAEBY-D@T IMO_
OR
STORAGE CONDITIONS
Store in clean, dry area. Donot heat above deg F.
125
TITLE III HAZARD CLASSIFICATIONS
Acute Yes
Chronic No
Fire _- No
Reactivity No
~
Pressure No
LISTS~
Extremely Hazardous Substance -No
CERCLA Hazardous Substance -(Yes)*
Toxic Chemicals -(Yes)**
*Methanol component only
**Methanol and Ethane, l,l,2-Trichloro-l,2,2-Trifluoro-
components only
ADDF~ONAL nqFORMA~ON AND REFERENCES
*NOTE CONTINUED FROM THE EXPOSURE LIMITS SECTION
The "Skin" notation indicates that methanol can penetrate
skin. Therefore, control of inhalation alone may not be
sufficient to prevent an excessive dose; skin contact should
be avoided.
For further information, see Du Pont bulletin S-34, The
"FREON" Compounds and Safety.
Thedata in this Material Safety DataSheet relates only to the specific material designated
herein and
doesnot relate to use in combinationwith anyother material or in any process.
Responsibility for MSDS: W.J. Brock
Du Pont Chemicals
P. O. Box 80709, ChestnutRun
Wilmington, DE19880-0709
(continued)
2044FR Page7
?",
302-999-5072
# Indicates
updated
section.
End of MSDS
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2044FR Page 8
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