TriLink BioTechnologies, Inc. Phone: (858) 546-0004
9955 Mesa Rim Road (800) 863-6801
San Diego, California 92121 Fax: (858) 546-0020
MATERIAL SAFETY DATA SHEET
1. CHEMICAL IDENTIFICATION
Custom Synthesized CleanAmpTM Primer
CATALOG NUMBER:
CHEMICAL NAME: Oligonucleotide
CHEMICAL FAMILY: Nucleic Acids
2. COMPOSITION/INGREDIENTS
CAS NUMBER: None
MOLECULAR FORMULA: Sequence Specific
COMPONENTS: Sequence Specific
3. HAZARDS IDENTIFICATION
MEDICAL CONDITIONS AGGRAVATED: Unknown, Custom Compound, Sequence Specific
PRIMARY ROUTES OF ENTRY: Ingestion
PEL: Unknown, Custom Compound, Sequence Specific
TLV: Unknown, Custom Compound, Sequence Specific
LD50: Unknown, Custom Compound, Sequence Specific
CARCINOGENICITY: Unknown, Custom Compound, Sequence Specific
TOXICITY: Unknown, Custom Compound, Sequence Specific
RTECS #: Unknown, Custom Compound, Sequence Specific
ACUTE EFFECTS: Unknown, Custom Compound, Sequence Specific
CHRONIC EFFECTS: Unknown, Custom Compound, Sequence Specific
4. FIRST AID MEASURES
EYES: Immediately flush eyes with copious amounts of water for at least 15 minutes.
SKIN: Immediately wash skin with soap and copious amounts of water.
INHALATION: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult,
give oxygen.
INGESTION: If swallowed, wash out mouth with water provided person is conscious. Call a physician.
OTHER: Wash contaminated clothing before re-use.
5. FIRE FIGHTING MEASURES
UPPER FLAMMABLE LIMIT: Unknown, Custom Compound, Sequence Specific
LOWER FLAMMABLE LIMIT: Unknown, Custom Compound, Sequence Specific
UPPER EXPLOSION LIMIT: Unknown, Custom Compound, Sequence Specific
LOWER EXPLOSION LIMIT: Unknown, Custom Compound, Sequence Specific
FLASHPOINT: Unknown, Custom Compound, Sequence Specific
AUTOIGNITION TEMPERATURE: Unknown, Custom Compound, Sequence Specific
FIRE EXTINGUISHING MEDIA: Water spray, carbon dioxide, dry chemical powder, or
appropriate foam.
UNUSUAL FIRE/EXPLOSION DATA: None Known
6. ACCIDENTAL RELEASE MEASURES
Wear respirator, chemical safety goggles, rubber boots, and heavy rubber gloves. Clean up contaminated area
with a moistened towel, place in a bag, and hold for waste disposal. Ventilate area and wash spill site after
material pickup is complete.
7. HANDLING AND STORAGE
Recommended storage at -20掳C or less. Product should left at room temperature for short intervals only.
8. EXPOSURE CONTROLS/EMPLOYEE PROTECTION
Wear appropriate NIOSH/MSHA-approved respirator, chemical-resistant gloves, safety goggles, and other
protective clothing. Safety shower and eye bath. Mechanical exhaust required. Wash thoroughly after
handling.
9. PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE: Clear Liquid
BOILING POINT: Custom Compound, Sequence Specific
MELTING POINT: Custom Compound, Sequence Specific
FREEZING POINT: Custom Compound, Sequence Specific
pH: Custom Compound, Sequence Specific
SOLUBILITY: Any aqueous solution
VAPOR DENSITY: Custom Compound, Sequence Specific
VAPOR PRESSURE: Custom Compound, Sequence Specific
10. STABILITY & REACTIVITY
STABILITY: Stable Material, hazardous polymerization will not occur.
INCOMPATIBILITY: Strong oxidizing agents
HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS:
Toxic fumes of carbon monoxide, carbon dioxide, nitrogen oxides, and phosphorus oxides
11. TOXICOLOGICAL INFORMATION
May be fatal if swallowed. Harmful if inhaled. May be harmful if absorbed through the skin. Causes eye and
skin irritation. Material is irritating to mucous membranes and upper respiratory tract. Exposure can cause:
CNS depression, gastrointestinal disturbances, narcotic effect, damage to the eyes, damage to the liver,
damage to the heart, damage to the kidneys. May cause convulsions. Target organs: eyes, nerves, liver,
kidneys.
12. ECOLOGICAL INFORMATION
Unknown
13. WASTE DISPOSAL
Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local environmental regulations.
TriLink BioTechnologies, Inc. believes the above information to be accurate, but not necessarily all-inclusive, and thus should only be used as a
guide in the handling and use of this material. The data in this MSDS relates only to the specific material designated herein and does not relate to
use in combination with any other material or in any process. TriLink BioTechnologies, Inc. shall not take responsibility for any damage
resulting from handling or from contact with the above product. The information in this material safety data sheet meets the requirements of the
United States Occupational Safety and Health Act and regulations promulgated thereunder 29 CFR 搂 1910.1200.
TriLink BioTechnologies, Inc. Phone: (858) 546-0004
9955 Mesa Rim Road (800) 863-6801
San Diego, California 92121 Fax: (858) 546-0020
MATERIAL SAFETY DATA SHEET
1. CHEMICAL IDENTIFICATION
CATALOG NUMBER: DMSO
CHEMICAL NAME: Dimethyl Sulfoxide
CHEMICAL FAMILY: Nucleic Acids
2. COMPOSITION/INGREDIENTS
CAS NUMBER: 67-68-5
MOLECULAR FORMULA: C2H6OS
COMPONENTS: Dimethyl Sulfoxide
3. HAZARDS IDENTIFICATION
MEDICAL CONDITIONS AGGRAVATED: Preexisting skin disease
PRIMARY ROUTES OF ENTRY: Ingestion, skin absorption, skin contact, eye contact,
inhalation
PEL: N/A
TLV: N/A
LD50/LC50: Draize test, rabbit, eye: 100 mg;
Draize test, rabbit, eye: 500 mg/24H Mild;
Draize test, rabbit, skin: 500 mg/24H Mild;
Oral, mouse: LD50 = 7920 mg/kg;
Oral, rat: LD50 = 14500 mg/kg;
Skin, rat: LD50 = 40 gm/kg;
CARCINOGENICITY: Not listed by ACGIH, IARC, NTP or CA Prop 65
TOXICITY: May be fatal if swallowed. Harmful if inhaled. May
be harmful if absorbed through the skin
RTECS #: N/A
ACUTE EFFECTS: Harmful if inhaled. Causes respiratory tract irritation,
headache, nausea, dizziness and drowsiness. Harmful
if swallowed. Can cause dizziness, drowsiness,
nausea, vomiting, cramps, and chills
CHRONIC EFFECTS: Long-term skin application of 80-90% DMSO has
produced CNS effects (such as fatigue, nausea,
vomiting, sedation, dizziness and headache), and
dermatitis (such as redness, dryness and scaling) in
volunteers. A garlic-like breath odor has been noted
4. FIRST AID MEASURES
EYES: Immediately flush eyes with copious amounts of water for at least 15 minutes.
SKIN: Immediately wash skin with soap and copious amounts of water.
INHALATION: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult,
give oxygen.
INGESTION: If swallowed, wash out mouth with water provided person is conscious. Call a physician.
OTHER: Wash contaminated clothing before re-use.
5. FIRE FIGHTING MEASURES
UPPER FLAMMABLE LIMIT: N/A
LOWER FLAMMABLE LIMIT: N/A
UPPER EXPLOSION LIMIT: 42%
LOWER EXPLOSION LIMIT: 3.5%
FLASHPOINT: 188.6掳F, 87掳C; Method: Closed Cup
AUTOIGNITION TEMPERATURE: 301掳C
FIRE EXTINGUISHING MEDIA: Water spray, carbon dioxide, dry chemical powder, or
appropriate foam.
UNUSUAL FIRE/EXPLOSION DATA: N/A
6. ACCIDENTAL RELEASE MEASURES
Wear respirator, chemical safety goggles, rubber boots, and heavy rubber gloves. Clean up contaminated area
with dry lime, sand, or soda ash. Place in covered containers using non-sparking tools and transport outdoors.
Ventilate area and wash spill site after material pickup is complete. In case of leak or spill evacuate area.
Avoid contaminating water supply. Avoid contaminating sewers and waterways.
7. HANDLING AND STORAGE
HANDLING: Avoid prolonged or repeated exposure. Avoid inhalation. Avoid contact with DMSO
solutions containing toxic materials or material with unknown toxicological properties. DMSO is readily
absorbed through skin and may carry such materials into the body.
STORAGE: Store under inert gas. Keep tightly closed. Keep away from sparks and open flame. Store in a
dry cool place. Hygroscropic.
8. EXPOSURE CONTROLS/EMPLOYEE PROTECTION
Wear appropriate NIOSH/MSHA-approved respirator, chemical-resistant gloves, safety goggles, and other
protective clothing. Safety shower and eye bath. Mechanical exhaust required. Wash thoroughly after
handling. Wash contaminated clothing before use.
9. PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE: Clear Liquid
BOILING POINT: 189掳C
MELTING POINT: 18.4掳C
FREEZING POINT: N/A
pH: N/A
SOLUBILITY: Soluble
VAPOR DENSITY: 2.7 g/l
VAPOR PRESSURE: 0.42 mmHg @ 20掳C
10. STABILITY & REACTIVITY
STABILITY: Stable material, hazardous polymerization will not occur.
INCOMPATIBILITY: Acid chlorides, phosphorus halides, strong oxidizing agents, strong acids, strong
reducing agents
HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS:
Carbon monoxide, Carbon dioxide, Sulfur Dioxide
11. TOXICOLOGICAL INFORMATION
Causes eye and skin irritation. Material is irritating to mucous membranes and upper respiratory tract.
Exposure can cause: CNS depression, gastrointestinal disturbances, narcotic effect, damage to the eyes,
damage to the liver, damage to the heart, damage to the kidneys. May cause convulsions. Target organs: eyes,
nerves, liver, kidneys.
12. ECOLOGICAL INFORMATION
ECOTOXICITY: N/A
ENVIRONMENTAL: Terrestrial: Expected to be mobile in soil, due to its high water solubility. Some
volatilization from dry soil and surfaces may be expected. Aquatic: DMSO disproportionates in water to
dimethyl sulfide and dimethyl sulfone, a reaction catalyzed by light. Atmospheric: Exists primarily in the
vapor phase and can be removed by both wet and dry deposition. It will react with photochemically-produced
hydroxyl radicals with a half-life of about 7 hr. DMSO is very difficult to biodegrade.
PHYSICAL: N/A
OTHER: Bacterial decomposition of DMSO during wastewater treatment can result in the release of
dimethyl sulfide, a volatile substance with a strong, disagreeable odor.
13. WASTE DISPOSAL
Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the
material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and
scrubber. Observe all federal, state, and local environmental regulations.
TriLink BioTechnologies, Inc. believes the above information to be accurate, but not necessarily all-inclusive, and thus should only be used as a
guide in the handling and use of this material. The data in this MSDS relates only to the specific material designated herein and does not relate to
use in combination with any other material or in any process. TriLink BioTechnologies, Inc. shall not take responsibility for any damage
resulting from handling or from contact with the above product. The information in this material safety data sheet meets the requirements of the
United States Occupational Safety and Health Act and regulations promulgated thereunder 29 CFR 搂 1910.1200.
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