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File Name: tissuetherapies_com_VG_MSDS_05.asp

                                                                 Title:     VitroGro MSDS
Code: F-020
Version: 001



Material Safety Data Sheet


VitroGro庐
Tissue Therapies Limited



1. Product Information

Product Name: VitroGro庐 kit 鈥? cell culture coating kit and/or medium additive.

Stock Number: VGK01

Manufacturer: Tissue Therapies Ltd
GPO Box 1596,
Brisbane, Queensland, 4001, Australia

Product Use: This product is for laboratory research use or further evaluation and is not
intended for animal or human diagnostic, therapeutic, or other clinical use,
unless otherwise indicated.


2. Composition, Information on Ingredients

Reagent A: Vitronectin in PBS containing 175 mM Ammonium Sulfate.
Reagent B: Insulin-like Growth Factor Binding Protein-3 (IGFBP-3) in 10 mM Acetic acid.
Reagent C: Insulin-like Growth Factor-1 (IGF-1) in 10 mM Hydrochloric acid.
Reagent D: Epidermal Growth Factor (EGF) in 10 mM Hydrochloric acid.

Human Vitronectin is purified from human plasma that has been tested by the American Red
Cross and found to be non-reactive for HIV-1 and Human T-cell leukaemia virus type-1
(HTLV-1) antibody and antigen, Hepatitis B surface antigen (HBsAg) and antibodies to
Hepatitis C.

Caution: These results are subject to the limitations of the virus detection assays. No known
test methods offer complete assurance that products derived from human tissue will not
transmit infectious agents. Observe universal precautions when working with this product.

IGFBP-3, IGF-1 and EGF are recombinant human proteins produced in E.coli.


3. Hazards Identification

EMERGENCY OVERVEIW
Occupational exposure presents little or no health hazard. Human Vitronectin is purified from
screened human blood donors indicating due care should be taken to prevent direct human
contact.

Potential Health Effects:

Eye: May cause eye irritation.
Skin: May cause skin irritation.
Inhalation: No toxicity expected from inhalation.
Ingestion: May cause irritation to mouth, throat and stomach.
Cancer: No data on cancer exists.




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Title: VitroGro MSDS
Code: F-020
Version: 001



VitroGro Material Safety Data Sheet Continued鈥︹??..


4. First Aid Measures

Eye: Flush with water for at least 15 minutes. Remove contact lenses.
Skin: Wash with soapy water. Remove contaminated clothes and wash.
Ingestion: Give plenty of water. Be prepared to induce vomiting upon Physicians advice.
Inhalation: If symptomatic remove person to fresh air.

Seek medical attention if symptoms develop (redness, itching, discomfort etc.).


5. Fire Fighting Measures

Flash-point: Not available
Auto-ignition temperature: Not available

Extinguishing Media: Use appropriate means for surrounding area

Hazardous combustion products: None known to exist


6. Accidental Release Measures

Absorb spills using common absorbent material and deposit in appropriate containers for
disposal.


7. Handling and Storage

Keep closed or covered when not in use. Observe aseptic technique when open or in use.

Store at -70oC.


8. Exposure Controls, Personal Protection

Exposure limits: No hazardous components under normal operating conditions

Eye: Safety glasses,
Skin: Gloves, as minimum hand protection, and laboratory coat,
Respiratory: No respiratory protection required under normal usage and operating
conditions,


9. Physical and Chemical Properties

Appearance: Clear to mildly turbid liquid,
Odour: No odour,
Volatiles: Not established, none expected.


10. Stability and Reactivity

Stability: Stable under ordinary conditions of use and storage,
Hazardous products: No hazardous decomposition products known or expected,
Hazardous polymerisation: Not expected to occur.




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Title: VitroGro MSDS
Code: F-020
Version: 001


VitroGro Material Safety Data Sheet Continued鈥︹??..


11. Toxicological Information

Not determined. No data for carcinogenicity or organ studies or acute toxicity.


12. Ecological Information

No eco-toxicological information available. Bio-concentration is not expected to occur for
disposal or storage.


13. Disposal Considerations

Dispose of in accordance with relevant regulations and institutional policy.


14. Transport Information

Proper Shipping Name: Not regulated
Conditions: Transport in dry ice


15. Regulatory Information

This product is for laboratory research use or further evaluation and is not intended for animal
or human diagnostic, therapeutic, or other clinical use, unless otherwise indicated. It should
be handled by technically qualified individuals.

No hazardous components are identified.



END OF DOCUMENT




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