BIO BASIC INC.
160 TORBAY ROAD MARKHAM ONTARIO L3R 1G6 CANADA
TEL: (905) 474 4493, (800) 313 7224 FAX: (905) 474 5794
MATERIAL SAFETY DATA SHEET
REQUIRED UNDER SAFETY AND HEALTH REGULATION FOR SHIP REPAIRING
MANUFACTURER鈥橲 NAME: BIO BASIC INC.
TEL: (905) 474 4493
FAX: (905) 474 5794
FOR CHEMICAL EMERGENCY (416) 995 9730
ADDRESS 160 TORBAY ROAD MARKHAM
ONTARIO L3R 1G6 CANADA
DATE PREPARED: 05-31-2007
SECTION 1. - - - - - - - - - CHEMICAL IDENTIFICATION- - - - - - - - - -
CODE #: BS380, BS381, BS382, BS384, BS386, BS387
NAME: PROTEINASE INHIBITOR COCKTAIL FOR PROTEIN EXTRACTION
SECTION 2. - - - - - COMPOSITION/INFORMATION ON INGREDIENTS - - - - - -
Ingredient Name EC Number CAS No. R-Phrases% Symbol
Dimethyl Sulfoxide (DMSO) 67-68-5 45-65 200-664-3 Xn R36/37/38, R42
SECTION 3. - - - - - - - - - - HAZARDS IDENTIFICATION - - - - - - - - -
United States
Review the most current and approved institutional guideline, protocol, standard operating procedure(s) and
MSDS(s)
for the proper handling of institutional materials/equipment associated with the use of this product.
Emergency Overview
WARNING!
CONTAINS MATERIAL WHICH CAUSES DAMAGE TO THE FOLLOWING
ORGANS:
LUNGS, GASTROINTESTINAL TRACT, SKIN, EYES, EYE, LENS OR CORNEA.
MAY CAUSE RESPIRATORY TRACT, EYE AND SKIN IRRITATION.
MAY CAUSE ALLERGIC RESPIRATORY REACTION.
COMBUSTIBLE LIQUID AND VAPOR.VAPOR MAY CAUSE FIRE.
Keep away from heat, sparks and flame. Avoid contact with eyes, skin and clothing. Do not breathe vapor or mist.
Keep container closed. Use only with adequate ventilation. Wash thoroughly after handling.
Routes of Entry Absorbed through skin. Eye contact. Inhalation. Ingestion.
Potential Acute Health Effects Hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of
inhalation (lung irritant, lung sensitizer).
Carcinogenic Effects Data CARCINOGENIC EFFECTS: Classified None., 4 (No evidence.) by NTP, None. by
NIOSH [Dimethyl Sulfoxide (DMSO)].MUTAGENIC EFFECTS: Not available.TERATOGENIC EFFECTS: Not
available.
SECTION 4. - - - - - - - - - - FIRST-AID MEASURES- - - - - - - - - - -
Inhalation
Hazardous in case of inhalation (lung irritant, lung sensitizer).
Ingestion
Hazardous in case of ingestion
Skin Contact. Sensitization of the product: Not available.
Hazardous in case of skin contact (irritant). Skin inflammation is characterized by itching, scaling, reddening, or,
occasionally, blistering.
Eye Contact Hazardous in case of eye contact (irritant).
Aggravating conditions Repeated or prolonged exposure is not known to aggravate medical condition.
First-Aid Measures
Inhalation
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention.
Ingestion
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if
symptoms appear.
Skin Contact
In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove
contaminated clothing and shoes. Wash clothing before reuse.
Thoroughly clean shoes before reuse. Get medicalattention. Check for and remove any contact lenses.
Eye Contact In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical
attention.
SECTION 5. - - - - - - - - - FIRE FIGHTING MEASURES - - - - - - - - - -
Flammability of the Product Combustible.
Flash PointsThe lowest known value is CLOSED CUP: 89掳 (192.2掳 ). OPEN CUP: 94.9掳 (202.8掳 (Dimethyl
C F C F).
Sulfoxide (DMSO))
Fire Fighting Media
and InstructionsSMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use
water jet.
Protective Clothing (Fire) Be sure to use an approved/certified respirator or equivalent.
Special Remarks on Fire Hazards
Combustible when exposed to heat or flame. Upon heating above 100C (212 F), sulfur dioxide is emitted.
When DMSO undergoes hazardous thermo-oxidative degradation it may produce formaldehyde, methyl mercaptan,
and sulfur dioxide. (Dimethyl Sulfoxide (DMSO))
Hazardous thermal (de)composition
Products These products are carbon oxides (CO, CO2), sulfur oxides (SO2, SO3...).
SECTION 6. - - - - - - - - ACCIDENTAL RELEASE MEASURES- - - - - - - - -
Combustible material.
Environmental Precautions and
Personal precautions Splash goggles. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator
or equivalent. Gloves.
Clean-up Methods
Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. Finish cleaning by spreading
water on the contaminated surface and allow to evacuate through the sanitary system. Be careful that the product
is not present at a concentration level above TLV. Check TLV on the MSDS and with local authorities.
Small Spill and Leak Absorb with an inert material and put the spilled material in an appropriate waste disposal.
SECTION 7. - - - - - - - - - - HANDLING AND STORAGE- - - - - - - - - - -
Handling
Keep away from heat, sparks and flame. Keep container closed. Use only with adequate ventilation. To avoid fire,
minimize ignition sources.
Storage
Keep container in a cool, well-ventilated area. Keep container tightly closed and sealed until ready for use. Avoid
all possible sources of ignition (spark or flame).
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific
applications.
SECTION 8. - - - - - - EXPOSURE CONTROLS/PERSONAL PROTECTION- - - - - -
CHEMICAL SAFETY GOGGLES.
COMPATIBLE CHEMICAL-RESISTANT GLOVES.
NIOSH/MSHA-APPROVED RESPIRATOR.
SAFETY SHOWER AND EYE BATH.
MECHANICAL EXHAUST REQUIRED.
DO NOT BREATHE VAPOR.
AVOID CONTACT WITH EYES, SKIN AND CLOTHING.
WASH THOROUGHLY AFTER HANDLING.
KEEP TIGHTLY CLOSED.
STORE IN A COOL DRY PLACE.
SECTION 9. - - - - - - - PHYSICAL AND CHEMICAL PROPERTIES - - - - - - -
Physical State and Odor
Liquid. Odorless.
Boiling/Condensation Point
Color The lowest known value is 189掳 (372.2掳 (Dimethy l Sulfoxide (DMSO)). Cloudy.
C F)
Melting/Freezing Point
May start to solidify at 18.5掳 (65.3掳 based on d ata for: Dimethyl Sulfoxide (DMSO).
C F)
Specific Gravity The only known value is 1.1 (Water = 1) (Dimethyl Sulfoxide (DMSO)).
Vapor Pressure The highest known value is 0.1 kPa (@ 20掳 (Dimeth yl Sulfoxide (DMSO)).
C)
Vapor Density The highest known value is 2.7 (Air = 1) (Dimethyl Sulfoxide (DMSO)).
SECTION 10. - - - - - - - - -STABILITY AND REACTIVITY - - - - - - - - -
Stability and Reactivity
The product is stable.
SECTION 11. - - - - - - - - - TOXICOLOGICAL INFORMATION - - - - - - - -
Toxicity to Animals
Acute oral toxicity (LD50): 200 mg/kg (wild bird species) (Calculated value for the mixture).
Chronic Effects on Humans
CARCINOGENIC EFFECTS: Classified None., 4 (No evidence.) by NTP, None. by NIOSH [Dimethyl Sulfoxide
(DMSO)].
Other Toxic Effects on Humans
Hazardous in case of eye contact (irritant), of ingestion, of inhalation (lung irritant, lung sensitizer).
SECTION 12. - - - - - - - - - ECOLOGICAL INFORMATION - - - - - - - - - -
DATA NOT YET AVAILABLE.
SECTION 13. - - - - - - - - - DISPOSAL CONSIDERATIONS - - - - - - - - -
Waste Information
Waste must be disposed of in accordance with federal, state and local environmental control regulations.
SECTION 14. - - - - - - - - - - TRANSPORT INFORMATION - - - - - - - - -
NOT REGULATED
SECTION 15. - - - - - - - - - REGULATORY INFORMATION - - - - - - - - -
Irritating substance. HCS Classification
Label Requirements
(Europe) R36/37/38- Irritating to eyes, respiratory system and skin.
R42- May cause sensitization by inhalation.
S2- Keep out of the reach of children.
S23- Do not breathe gas/fumes/vapour/spray [***]
S46- If swallowed, seek medical advice immediately and show this container or label.
HCS Classification Irritating substance.
U.S. Federal Regulations
TSCA 8(b) inventory: Dimethyl Sulfoxide (DMSO)
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean air act (CAA) 112 accidental release prevention: No products were found.
Clean air act (CAA) 112 regulated flammable substances: No products were found.
Clean air act (CAA) 112 regulated toxic substances: No products were found.
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: Dimethyl Sulfoxide (DMSO)
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: Dimethyl Sulfoxide
(DMSO): immediate health hazard, delayed
health hazard
SARA 313 toxic chemical notification and release reporting: No products were found.
WHMIS (Canada) CLASS B-3: Combustible liquid with a flash point between 37.8掳 (100掳F) and
C
93.3掳 (200掳F).
C
CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC).
CLASS D-2A: Material causing other toxic effects (VERY TOXIC).
SECTION 16. - - - - - - - - - - OTHER INFORMATION- - - - - - - - - - - -
THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO
BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. BIO BASIC INC.SHALL NOT
BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING OR FROM CONTACT
WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR PACKING SLIP FOR
ADDITIONAL TERMS AND CONDITIONS OF SALE.
-
|