Eng
Material Safety Data Sheet
Conforms to 93/112/EC and ISO 11014-1
Responsible Name Pierce Administration
Section 1. Chemical Product and Company Identification
Reacti-Bind鈩? DNA Coating Solution
Product name
Product No. 0017250
Supplier In USA:In Europe: Manufacturer Pierce Biotechnology
Pierce Perbio Science P.O. Box 117
P.O. Box 117
Industriezone III Rockford, IL 61105
Rockford, IL 61105
Industrielaan 27 USA
USA 9320 Erembodegem-Aalst 815.968.0747 or
815.968.0747 or
Belgium 1.800.874.3723
1.800.874.3723
Tel:+32 53 83 44 04
Fax:+32 53 83 76 38
In Case of Emergency CALL CHEMTREC: Print Date 11/7/2002
800.424.9300 Validation Date 11/4/2002
OUTSIDE US:
MSDS# 2288
202.483.7616
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
Section 2. Composition, Information on Ingredients
Substance/Preparation : Preparation
CAS No. EC Number Symbol R-Phrases
Ingredient Name %
1) Reacti-Bind DNA Coating Solution Ingredient 1 65-80 231-984-1 Xi R36/37/38
Section 3. Hazards Identification
United States Review the most current and approved institutional guideline, protocol, standard operating procedure(s) and MSDS(s)
for the proper handling of institutional materials/equipment associated with the use of this product.
Emergency Overview WARNING!
CAUSES SEVERE RESPIRATORY TRACT AND SKIN IRRITATION.
MAY CAUSE EYE IRRITATION.
CONTAINS MATERIAL WHICH MAY CAUSE DAMAGE TO THE FOLLOWING ORGANS: LUNGS,
GASTROINTESTINAL TRACT.
Avoid contact with eyes, skin and clothing. Avoid breathing vapor or mist. Keep container closed. Use only with adequate
ventilation. Wash thoroughly after handling.
Routes of Entry Absorbed through skin. Eye contact. Inhalation. Ingestion.
Potential Acute Health Effects Very hazardous in case of skin contact (irritant), of inhalation (lung irritant). Hazardous in case of eye contact (irritant), of
ingestion, .
Carcinogenic Effects Data CARCINOGENIC EFFECTS: Classified None. by NIOSH [Reacti-Bind DNA Coating Solution Ingredient 1].
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
Medical Conditions Aggravated by Repeated or prolonged exposure is not known to aggravate medical condition.
Overexposure:
Overexposure /Signs/Symptoms Not available.
Europe
Classification R36/37/38
Physical/chemical hazards Not applicable.
Human health hazards Irritating to eyes, respiratory system and skin.
Environmental hazards Not applicable.
See Toxicological Information (section 11)
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Reacti-Bind鈩? DNA Coating Solution
Section 4. First Aid Measures
Notice to Reader Get immediate medical attention.
Effects and symptoms
Inhalation Very hazardous in case of inhalation (lung irritant).
Ingestion Hazardous in case of ingestion.
Skin Contact Sensitization of the product: Not available.
Very hazardous in case of skin contact (irritant). Skin inflammation is characterized by itching, scaling, reddening, or,
occasionally, blistering.
Eye Contact Hazardous in case of eye contact (irritant).
Aggravating conditions Repeated or prolonged exposure is not known to aggravate medical condition.
First-Aid Measures
Inhalation If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical
attention immediately.
Ingestion Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious
person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear.
Skin Contact In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing
and shoes. Cover the irritated skin with an emollient. Cold water may be used.Wash clothing before reuse. Thoroughly
clean shoes before reuse. Get medical attention immediately.
Eye Contact Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Cold water may be used. Get medical attention.
Notes to Physician Not available.
Protection of first-aiders Not available.
Section 5. Fire Fighting Measures
Flammability of the Product Non-flammable.
Flash Points Not applicable.
Fire Hazards in Presence of Various Not applicable.
Substances
Fire Fighting Media Not applicable.
and Instructions
Protective Clothing (Fire) Not applicable.
Hazardous thermal (de)composition Not applicable.
products
Section 6. Accidental Release Measures
Personal precautions Splash goggles. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Environmental Precautions and Absorb with an inert material and put the spilled material in an appropriate waste disposal. Finish cleaning by spreading
Clean-up Methods water on the contaminated surface and allow to evacuate through the sanitary system.
Small Spill and Leak Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal container.
Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority
requirements.
Section 7. Handling and Storage
Handling Avoid contact with eyes, skin, and clothing. Avoid breathing vapors or spray mists. Keep container closed. Use only
with adequate ventilation. Wash thoroughly after handling.
Storage Keep container tightly closed. Keep container in a cool, well-ventilated area.
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
Packaging materials
Suitable / Not suitable Use original container.
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Reacti-Bind鈩? DNA Coating Solution
Section 8. Exposure Controls/Personal Protection
Engineering Controls Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their
respective threshold limit value.
Exposure Limit Values
Ingredient Name Occupational Exposure Limits
United States
1) Reacti-Bind DNA Coating Solution Ingredient 1 Not available.
Sweden
1) Reacti-Bind DNA Coating Solution Ingredient 1 Not available.
Denmark
1) Reacti-Bind DNA Coating Solution Ingredient 1 Not available.
Norway
1) Reacti-Bind DNA Coating Solution Ingredient 1 Not available.
France
1) Reacti-Bind DNA Coating Solution Ingredient 1 Not available.
Netherlands
1) Reacti-Bind DNA Coating Solution Ingredient 1 Not available.
Germany
1) Reacti-Bind DNA Coating Solution Ingredient 1 Not available.
Personal Protection
Splash goggles.
Eyes
Lab coat.
Body
Gloves.
Hands
Respirator is not needed under normal and intended conditions of use, if exposures are kept below established limits.
Respiratory
Protective Clothing
(Pictograms)
Section 9. Physical and Chemical Properties
Physical State and Liquid. Odor Not available.
Appearance
Taste Not available.
Molecular Weight Not applicable.
Color Not available.
pH (1% Soln/Water) 6.1 [Acidic.]
Specific Gravity The only known value is 1.769 (Water = 1) (Reacti-Bind DNA Coating Solution Ingredient 1).
Dispersion Properties See solubility in water.
Solubility Partially soluble in cold water, hot water.
Insoluble in acetone.
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Reacti-Bind鈩? DNA Coating Solution
Section 10. Stability and Reactivity
Stability and Reactivity The product is stable.
Conditions to avoid Not available.
Materials to avoid Not available.
Hazardous Polymerization Will not occur.
Hazardous Decomposition Not applicable.
Products
Section 11. Toxicological Information
Toxicity to Animals Acute oral toxicity (LD50): 914 mg/kg (Mouse) (Calculated value for the mixture).
Chronic Effects on Humans CARCINOGENIC EFFECTS: Classified None. by NIOSH [Reacti-Bind DNA Coating Solution Ingredient 1].
Contains material which may cause damage to the following organs: lungs, gastrointestinal tract.
Other Toxic Effects on Humans Hazardous in case of eye contact (irritant), of ingestion, .
Special Remarks on Toxicity to Not available.
Animals
Special Remarks on Chronic Not available.
Effects on Humans
Special Remarks on Other Toxic Not available.
Effects on Humans
Section 12. Ecological Information
Mobility Not available.
Persistence/degradability Not available.
Bioaccumulative potential Not available.
Ecotoxicity Not available.
Germany water class VCI WGK: No products were found.
Section 13. Disposal Considerations
Waste Information Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Waste Stream Not available.
Consult your local or regional authorities.
Section 14. Transport Information
Contact the supplier for all information regarding the proper transportation method for this material.
1
Section 15. Regulatory Information
Label Requirements
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Reacti-Bind鈩? DNA Coating Solution
R36/37/38- Irritating to eyes, respiratory system and skin.
(Europe)
S24/25- Avoid contact with skin and eyes.
S36/37/39- Wear suitable protective clothing, gloves and eye/face protection.
Irritant
HCS Classification Irritating substance.
U.S. Federal Regulations TSCA 8(b) inventory: Reacti-Bind DNA Coating Solution Ingredient 1
TSCA 8(d) H and S data reporting: Reacti-Bind DNA Coating Solution Ingredient 1
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: Reacti-Bind DNA Coating Solution Ingredient 1
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: Reacti-Bind DNA Coating Solution Ingredient 1: immediate health
hazard
SARA 313 toxic chemical notification and release reporting: Reacti-Bind DNA Coating Solution Ingredient 1 70%
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean air act (CAA) 112 accidental release prevention: No products were found.
Clean air act (CAA) 112 regulated flammable substances: No products were found.
Clean air act (CAA) 112 regulated toxic substances: No products were found.
WHMIS (Canada) CLASS D-2A: Material causing other toxic effects (VERY TOXIC).
CEPA DSL: Reacti-Bind DNA Coating Solution Ingredient 1
International Regulations
EINECS Not available.
DSCL (EEC) R36/37/38- Irritating to eyes, respiratory system and skin.
International Lists Australia (NICNAS): Reacti-Bind DNA Coating Solution Ingredient 1
Germany water class: Reacti-Bind DNA Coating Solution Ingredient 1
Korea (TCCL): Reacti-Bind DNA Coating Solution Ingredient 1
Philippines (RA6969): Reacti-Bind DNA Coating Solution Ingredient 1
State Regulations Pennsylvania RTK: Reacti-Bind DNA Coating Solution Ingredient 1: (environmental hazard, generic environmental hazard)
Massachusetts RTK: Reacti-Bind DNA Coating Solution Ingredient 1
New Jersey: Reacti-Bind DNA Coating Solution Ingredient 1
California prop. 65: No products were found.
Section 16. Other Information
Hazardous Material National Fire Protection
* 1
Health
Fire Hazard
0
Information System Association (U.S.A.)
0
Fire Hazard
(U.S.A.)
1 0
Health Reactivity
0
Reactivity
Specific Hazard
h
Personal Protection
References Not available.
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Reacti-Bind鈩? DNA Coating Solution
History of Document Changes Any information changes since last document version are marked with a triangle symbol.
Full text of R-Phrases Irritating to eyes, respiratory system and skin.
referenced under headings 2 and 3:
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
Date of Previous Issue No Previous
Validated by Pierce Administration on 11/4/2002. Verified by Pierce Administration.
Validation
Printed 11/7/2002. Version 0.01
Notice to Reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its subsidiaries assumes any
liability whatsoever for the accuracy or completeness of the information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution.
Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.
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