Page 1/5
MATERIAL SAFETY DATA SHEET
Prepared in accordance with EU directive 91/155/EEC
Printed: 23.12.2006 Revised: 06.12.2006
1 Identification of the substance/preparation and of the company/undertaking
路 Product details
路 Trade name: 5-Fluoroorotic Acid
路 Application of the substance / the preparation: Laboratory chemicals
路 Manufacturer/Supplier:
Fermentas UAB
V.Graiciuno 8
LT-02241 Vilnius
Lithuania
Tel.: +370 5 2602131
Fax.: +370 5 2602142
路 Further information obtainable from:
Please visit our site: http://www.fermentas.com/
Contact us: info@fermentas.com
Or contact Fermentas distributor in your country.
路 Information in case of emergency:
Poison Information Centre, Mainz, Germany,
Tel.: +49 (0)6131 19240 / 24h
2 Composition/information on ingredients
路 Chemical characterization:
路 CAS No. Description
703-95-7 5-fluorouracil-4-carboxylic acid
路 Identification number(s)
路 EINECS Number: 211-876-0
3 Hazards identification
路 Hazard description:
Xn Harmful
路 Information concerning particular hazards for human and environment:
R 22 Harmful if swallowed.
R 36/37/38 Irritating to eyes, respiratory system and skin.
4 First aid measures
路 General information:
Symptoms of poisoning may even occur after several hours; therefore medical observation for at
least 48 hours after the accident.
路 After inhalation: In case of unconsciousness place patient stably in side position for transportation.
(Contd. on page 2)
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Page 2/5
MATERIAL SAFETY DATA SHEET
Prepared in accordance with EU directive 91/155/EEC
Printed: 23.12.2006 Revised: 06.12.2006
Trade name: 5-Fluoroorotic Acid
(Contd. of page 1)
路 After skin contact: Immediately wash with water and soap and rinse thoroughly.
路 After eye contact:
Rinse opened eye for several minutes under running water. If symptoms persist, consult a doctor.
路 After swallowing: Call for a doctor immediately.
5 Fire-fighting measures
路 Suitable extinguishing agents:
CO2, powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
路 Protective equipment: No special measures required.
6 Accidental release measures
路 Person-related safety precautions: Not required.
路 Measures for environmental protection: Do not allow to enter sewers/ surface or ground water.
路 Measures for cleaning/collecting:
Dispose contaminated material as waste according to item 13.
Ensure adequate ventilation.
7 Handling and storage
路 Handling:
路 Information for safe handling: Ensure good ventilation/exhaustion at the workplace.
路 Information about fire - and explosion protection: No special measures required.
路 Storage:
路 Requirements to be met by storerooms and receptacles: No special requirements.
路 Information about storage in one common storage facility: Not required.
路 Further information about storage conditions: Keep container tightly sealed.
8 Exposure controls/personal protection
路 Additional information about design of technical facilities: No further data; see item 7.
路 Ingredients with limit values that require monitoring at the workplace: Not required.
路 Additional information: The lists valid during the making were used as basis.
路 Personal protective equipment:
路 General protective and hygienic measures:
Keep away from foodstuffs, beverages and feed.
Immediately remove all soiled and contaminated clothing
Wash hands before breaks and at the end of work.
Avoid contact with the eyes and skin.
路 Respiratory protection:
In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer
exposure use self-contained respiratory protective device.
(Contd. on page 3)
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MATERIAL SAFETY DATA SHEET
Prepared in accordance with EU directive 91/155/EEC
Printed: 23.12.2006 Revised: 06.12.2006
Trade name: 5-Fluoroorotic Acid
(Contd. of page 2)
路 Protection of hands:
Protective gloves
The glove material has to be impermeable and resistant to the product/ the substance/ the
preparation.
Due to missing tests no recommendation to the glove material can be given for the product/ the
preparation/ the chemical mixture.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the
degradation
路 Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks
of quality and varies from manufacturer to manufacturer.
路 Penetration time of glove material
The exact break trough time has to be found out by the manufacturer of the protective gloves and has
to be observed.
路 Eye protection:
Tightly sealed goggles
9 Physical and chemical properties
路 General Information
Solid
Form:
White
Colour:
Odourless
Odour:
路 Change in condition
Melting point/Melting range: 268-269掳C
Boiling point/Boiling range: Undetermined.
Not applicable.
路 Flash point:
路 Flammability (solid, gaseous): Product is not flammable.
Product does not present an explosion hazard.
路 Danger of explosion:
Not determined.
路 Density:
路 Solubility in / Miscibility with
Slightly soluble.
water:
10 Stability and reactivity
路 Thermal decomposition / conditions to be avoided:
No decomposition if used according to specifications.
路 Dangerous reactions No dangerous reactions known.
(Contd. on page 4)
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MATERIAL SAFETY DATA SHEET
Prepared in accordance with EU directive 91/155/EEC
Printed: 23.12.2006 Revised: 06.12.2006
Trade name: 5-Fluoroorotic Acid
(Contd. of page 3)
路 Dangerous decomposition products: No dangerous decomposition products known.
11 Toxicological information
路 Acute toxicity:
路 LD/LC50 values relevant for classification:
703-95-7 5-fluorouracil-4-carboxylic acid
Oral LD50 981 mg/kg (mouse)
路 Primary irritant effect:
路 on the skin: Irritant to skin and mucous membranes.
路 on the eye: Irritating effect.
路 Sensitization: No sensitizing effects known.
12 Ecological information
路 General notes:
Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for water
Do not allow undiluted product or large quantities of it to reach ground water, water course or
sewage system.
13 Disposal considerations
路 Product:
路 Recommendation:
Must not be disposed together with household garbage. Do not allow product to reach sewage
system.
路 Uncleaned packaging:
路 Recommendation: Disposal must be made according to official regulations.
14 Transport information
路 Land transport ADR/RID (cross-border)
路 ADR/RID class: -
路 Maritime transport IMDG:
-
路 IMDG Class:
路 Marine pollutant: No
路 Air transport ICAO-TI and IATA-DGR:
路 ICAO/IATA Class: -
15 Regulatory information
路 Labelling according to EU guidelines:
The product has been classified and marked in accordance with EU Directives / Ordinance on
Hazardous Materials.
(Contd. on page 5)
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Page 5/5
MATERIAL SAFETY DATA SHEET
Prepared in accordance with EU directive 91/155/EEC
Printed: 23.12.2006 Revised: 06.12.2006
Trade name: 5-Fluoroorotic Acid
(Contd. of page 4)
路 Code letter and hazard designation of product:
Xn Harmful
路 Risk phrases:
22 Harmful if swallowed.
36/37/38 Irritating to eyes, respiratory system and skin.
路 Safety phrases:
23 Do not breathe gas/fumes/vapour/spray.
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
36/37 Wear suitable protective clothing and gloves.
60 This material and its container must be disposed of as hazardous waste.
16 Other information
This information is based on our present knowledge and shall be used only as a guide. However,
this shall not constitute a guarantee for any specific product features and shall not establish a
legally valid contractual relationship. Fermentas is not held liable for any damage resulting from
handling or from contact with the above mentioned products.
MSDS has been prepared in accordance with EU directives 67/548/EEC, 91/155/EEC and other
European Union legislation in force.
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