SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 19/OCT/2004
Date Updated: 12/MAR/2004
Version 1.3
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name A-AMYLASE FROM BACILLUS SPECIES
Product Number A6814
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
ALPHA-AMYLASE 9000-90-2 232-565-6 647-015-00-4
Synonyms alpha-Amylase * Amylase AD * Amylase THC 250 *
Amylogal CS * Amylolisin 5 * Amylopsin *
Bactosol TK * BAM 240 * BAN 120L * Biotex GT *
Biozyme F * Buclamase * Canalpha 600L * Clarase
* Denazyme SA 7 * Endoamylase * EC 3.2 1.1 *
Fortizyme * Fungamyl 300 L * G 995 * G6-Amylase
* G-zyme G 995 * Hitempase * Kleistase KD *
Kleistase L 1 * Kleistase T 5 * Kokugen K *
Maltogenase 4000L * Maxamyl * Maxamyl HT 3000 *
Maxamyl WL 15,000 * Maxilase * Pivozin *
Plurafact oxam * Ptyalin * Speedase HS *
Speedase M * Speedase XP 404 * Spitase CP 1 *
Sumizyme L * Taka-amylase * Taka-amylase A *
Taka-diastase * Takalite L 340 * Takatherm *
Tanase * Termamyl * Termamyl 60L * Termamyl 120L
* Termamyl 60T * Thermolase * Takalite * WC 8
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
May cause sensitization by inhalation.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If breathing becomes difficult,
call a physician.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Use extinguishing media appropriate to surrounding
fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Avoid contact with eyes, skin, and
clothing. Avoid inhalation. Avoid prolonged or repeated exposure.
STORAGE
Conditions of Storage: Keep tightly closed.
Store at -20掳C
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Color: Beige
Form: Powder
Property Value At Temperature or Pressure
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pH N/A
BP/BP Range N/A
MP/MP Range N/A
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density N/A
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Nature of decomposition products
not known.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: BU7432500
ACUTE TOXICITY
LD50
Oral
Rat
> 7500 mg/kg
LD50
Oral
Mouse
> 15000 mg/kg
SENSITIZATION
Respiratory: May cause allergic respiratory reaction.
SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
ROUTE OF EXPOSURE
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Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: May be harmful if inhaled. Material may be
irritating to mucous membranes and upper respiratory tract.
Ingestion: May be harmful if swallowed.
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
Non-hazardous for road transport.
IMDG
Non-hazardous for sea transport.
IATA
Non-hazardous for air transport.
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 647-015-00-4
INDICATION OF DANGER: Xn
Harmful.
R-PHRASES: 42
May cause sensitization by inhalation.
S-PHRASES: 22 24 36/37
Do not breathe dust. Avoid contact with skin. Wear suitable
protective clothing and gloves.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 1
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2004 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
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DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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