SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 16/JUN/2005
Date Updated: 16/MAR/2004
Version 1.2
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name 4-CHLOROPHENYLMAGNESIUM BROMIDE, 1.0M
SOLUTION IN DIETHYL ETHER
Product Number 262188
Company Sigma-Aldrich Pty. Ltd.
12 Anella Avenue
Castle Hill NSW 2154
Australia
Technical Phone # +61 2 9841 0555 (1800 800 097)
Fax +61 2 9841 0500 (1800 800 096)
Emergency Phone # +44 8701906777 (1800 448 465)
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
4-CHLOROPHENYLMAGNESIUM BROMIDE, None None None
1.0M SOLUTION IN DIETHYL ETHER
Ingredient Name Percent CAS # EC no Annex I
Index Number
4-CHLOROPHENYLMAGNESIUM 24.326 873-77-8 212-853-8 None
BROMIDE
DIETHYL ETHER, INHIBITOR 75.674 60-29-7 200-467-2 603-022-00-4
FREE
Symbols: F+ Xn
R-Phrases: 12 19 22 66 67
Extremely flammable. May form explosive peroxides. Harmful if
swallowed. Repeated exposure may cause skin dryness or cracking.
Vapors may cause drowsiness and dizziness.
Formula C6H4BrClMg
Molecular Weight 215.77 AMU
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Extremely flammable. May form explosive peroxides. Harmful if
swallowed. Causes burns. Vapors may cause drowsiness and dizziness.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact, immediately flush eyes with copious amounts
of water for at least 15 minutes.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician. Do not induce vomiting.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Carbon dioxide, dry chemical powder, or appropriate
foam.
Unsuitable: Do not use water.
SPECIAL RISKS
Specific Hazard(s): Extremely flammable. Vapor may travel
considerable distance to source of ignition and flash back.
Explosion Hazards: Vapor may travel considerable distance to
source of ignition and flash back. Container explosion may occur
under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
SPECIFIC METHOD(S) OF FIRE FIGHTING
Use water spray to cool fire-exposed containers.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area. Shut off all sources of ignition.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Cover with dry-lime, sand, or soda ash. Place in covered
containers using non-sparking tools and transport outdoors.
Ventilate area and wash spill site after material pickup is
complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Do not get
in eyes, on skin, on clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed. Keep away from heat,
sparks, and open flame.
Unsuitable: Forms explosive peroxides on prolonged storage
Incompatible Materials: Do not allow contact with water
SPECIAL REQUIREMENTS: Light sensitive. Air sensitive. Reacts
ALDRICH - 262188 www.sigma-aldrich.com Page 2
violently with water. Heat sensitive.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Use nonsparking tools. Use only in a
chemical fume hood.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Discard contaminated
shoes. Wash thoroughly after handling.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
Special Protective Measures: Faceshield (8-inch minimum).
9 - Physical and Chemical Properties
Appearance Physical State: Liquid
Property Value At Temperature or Pressure
pH N/A
BP/BP Range N/A
MP/MP Range N/A
Flash Point -40 掳C Method: closed cup
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density 0.887 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Conditions of Instability: May form peroxides of unknown stability.
Conditions to Avoid: Do not allow water to enter container because
of violent reaction. Light. Heat. Air.
Materials to Avoid: Strong acids, Oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Hydrogen chloride gas, Hydrogen bromide gas.
ALDRICH - 262188 www.sigma-aldrich.com Page 3
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
SIGNS AND SYMPTOMS OF EXPOSURE
Material is extremely destructive to tissue of the mucous
membranes and upper respiratory tract, eyes, and skin.
Inhalation may result in spasm, inflammation and edema of the
larynxand bronchi, chemical pneumonitis, and pulmonary edema.
Symptoms of exposure may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea, and
vomiting. To the best of our knowledge, the chemical, physical,
and toxicological properties have not been thoroughly
investigated.
ROUTE OF EXPOSURE
Skin Contact: Causes burns.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: Causes burns.
Inhalation: May be harmful if inhaled. Material is extremely
destructive to the tissue of the mucous membranes and upper
respiratory tract. Material is irritating to mucous membranes
and upper respiratory tract.
Ingestion: Harmful if swallowed.
TARGET ORGAN INFORMATION
Central nervous system. Kidneys. Liver. G.I. System. Skeletal
muscle.
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Burn in a chemical incinerator equipped with an
afterburner and scrubber but exert extra care in igniting as this
material is highly flammable. Observe all federal, state, and
local environmental regulations.
14 - Transport Information
RID/ADR
UN#: 3399
Class: 4.3
PG: I
Proper Shipping Name: Organometallic substance,
liquid, water-reactive, flammable
IMDG
UN#: 3399
Class: 4.3
PG: I
Subrisk: 3
Proper Shipping Name: Organometallic substance,
liquid, water-reactive, flammable
Marine Pollutant: No
Severe Marine Pollutant: No
Technical Name: Required
ALDRICH - 262188 www.sigma-aldrich.com Page 4
IATA
UN#: 3399
Class: 4.3
PG: I
Subrisk: 3
Proper Shipping Name: Organometallic substance,
liquid, water-reactive, flammable
Inhalation Packing Group I: No
Technical Name: Required
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
INDICATION OF DANGER: F+ C
Extremely Flammable. Corrosive.
R-PHRASES: 12 19 22 34 67
Extremely flammable. May form explosive peroxides. Harmful if
swallowed. Causes burns. Vapors may cause drowsiness and
dizziness.
S-PHRASES: 9 16 29 33 26 36/37/39 45
Keep container in a well-ventilated place. Keep away from
sources of ignition - no smoking. Do not empty into drains.
Take precautionary measures against static discharges. In case
of contact with eyes, rinse immediately with plenty of water
and seek medical advice. Wear suitable protective clothing,
gloves, and eye/face protection. In case of accident or if you
feel unwell, seek medical advice immediately (show the label
where possible).
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
ALDRICH - 262188 www.sigma-aldrich.com Page 5
|