SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 18/AUG/2005
Date Updated: 17/JUN/2004
Version 1.3
According to 91/155/EEC
1 - Product and Company Information
Product Name DEUTERIUM OXIDE, STANDARD, 99.98 +/-
0.0 1 ATOM % D
Product Number 364312
Company Sigma-Aldrich Pty. Ltd.
12 Anella Avenue
Castle Hill NSW 2154
Australia
Technical Phone # +61 2 9841 0555 (1800 800 097)
Fax +61 2 9841 0500 (1800 800 096)
Emergency Phone # +44 8701906777 (1800 448 465)
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
DEUTERIUM OXIDE 7789-20-0 232-148-9 None
Formula D2O
Molecular Weight 20.03 AMU
Synonyms Deuterium oxide * Dideuterium oxide * Heavy
water * Heavy water-d2 * Water-d2 (9CI) *
Water(sup 2)-H2
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Not hazardous according to Directive 67/548/EEC.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If breathing becomes difficult,
call a physician.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Noncombustible. Use extinguishing media appropriate to
surrounding fire conditions.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
METHODS FOR CLEANING UP
Absorb on sand or vermiculite and place in closed containers for
disposal.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Avoid inhalation. Avoid contact
with eyes, skin, and clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed. Store under nitrogen.
SPECIAL REQUIREMENTS: Store under inert gas. Hygroscopic.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaust required.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
PERSONAL PROTECTIVE EQUIPMENT
Hand Protection: Protective gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Clear liquid
Color: Colorless
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 101.4 掳C 760 mmHg
MP/MP Range 3.8 掳C
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density 1.12 g/cm3
Partition Coefficient N/A
Viscosity N/A
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Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Conditions to Avoid: Moisture.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Oxides.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: ZC0230000
SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: May be harmful if inhaled. Material may be
irritating to mucous membranes and upper respiratory tract.
Ingestion: May be harmful if swallowed.
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Mouse
Dose: 840 GM/KG
Route of Application: Oral
Exposure Time: (14D MALE)
Result: Effects on Fertility: Male fertility index (e.g., #
males impregnating females per # males exposed to fertile
nonpregnant females).
Species: Mouse
Dose: 3360 GM/KG
Route of Application: Oral
Exposure Time: (56D PRE)
Result: Effects on Fertility: Female fertility index (e.g., #
females pregnant per # sperm positive females; # females
pregnant per # females mated ).
Species: Mouse
Dose: 2940 GM/KG
Route of Application: Oral
Exposure Time: (49D MALE)
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Result: Paternal Effects: Spermatogenesis (including genetic
material, sperm morphology,motility, and count).
Species: Mouse
Dose: 1680 GM/KG
Route of Application: Oral
Exposure Time: (28D MALE)
Result: Effects on Fertility: Male fertility index (e.g., #
males impregnating females per # males exposed to fertile
nonpregnant females). Effects on Fertility: Litter size (e.g.; #
fetuses per litter; measured before birth).
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
Non-hazardous for road transport.
IMDG
Non-hazardous for sea transport.
IATA
Non-hazardous for air transport.
15 - Regulatory Information
Not hazardous according to Directive 67/548/EEC.
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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