SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 10/FEB/2005
Date Updated: 12/MAR/2004
Version 1.4
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name BROMINE, 99.99+%
Product Number 328138
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
BROMINE 7726-95-6 231-778-1 035-001-00-5
Formula Br2
Molecular Weight 159.82 AMU
Synonyms Brom (German) * Brome (French) * Bromine
(ACGIH:OSHA) * Bromo (Italian) * Broom (Dutch) *
Dibromine
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Very toxic by inhalation. Causes severe burns. Very toxic to
aquatic organisms.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If breathing becomes difficult,
call a physician.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
CONDITIONS OF FLAMMABILITY
Vigorously supports combustion.
EXTINGUISHING MEDIA
Suitable: Noncombustible. Use water spray to cool fire-exposed
containers.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
Contact with other material may cause fire. May accelerate
combustion.
Explosion Hazards: Container explosion may occur under fire
conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area and keep personnel upwind.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Cover with dry-lime, sand, or soda ash. Place in covered
containers using non-sparking tools and transport outdoors.
Ventilate area and wash spill site after material pickup is
complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Do not get
in eyes, on skin, on clothing. Avoid prolonged or repeated
exposure. Handle bromine only with equipment made of Kynar,
Teflon, monel, Pyrex glass, and lead-lined steel.
STORAGE
Conditions of Storage: Keep tightly closed. Keep away from
combustible materials, heat, sparks, and open flame. Store in a
cool dry place.
Unsuitable: Do not store in polyethylene containers.
SPECIAL REQUIREMENTS: May develop pressure. Open carefully.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Use only in a chemical fume hood. Safety shower and eye bath.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling. Remove and wash contaminated
clothing promptly.
EXPOSURE LIMITS
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Country Source Type Value
Poland NDS 0.7 MG/M3
Poland NDSCh 2 MG/M3
Poland NDSP -
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 0.7 mg/m3
0.1 ppm
EXPOSURE LIMITS - GERMANY
Source Type Value
TRGS 900 OEL 0.7 mg/m3
0.1 ppm
Remarks: =1=
EXPOSURE LIMITS - NORWAY
Source Type Value
OEL 0.7 mg/m3
0.1 ppm
EXPOSURE LIMITS - SWEDEN
Source Type Value
LLV (Level0.7 mg/m3
0.1 ppm
EXPOSURE LIMITS - SWITZERLAND
Source Type Value
OEL OEL 0.7 mg/m3
0.1 ppm
Remarks: K
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL OEL 0.66 mg/m3
0.1 ppm
OEL STEL 2 mg/m3
0.3 ppm
Remarks: Indicative limit value
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Self-contained breathing apparatus should
be worn
Eye Protection: Use safety shield.
Special Protective Measures: Impervious protective clothing.
9 - Physical and Chemical Properties
Appearance Physical State: Liquid
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 58 - 59 藲C
MP/MP Range -7.2 藲C
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure 175 mmHg 20 藲C
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SG/Density 3.11 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density 7.14 g/l
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Reducing agents, Alkali metals, Finely
powdered metals, Aluminum, Stainless steel Corrodes steel.,
Galvanized iron Copper, Copper alloys, Organic materials Bromine
will attack some types of plastics, rubber, and coatings
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Hydrogen bromide gas.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: EF9100000
ACUTE TOXICITY
LDLO
Oral
Human
14 mg/kg
LCLO
Inhalation
Human
1,000 ppm
LD50
Oral
Rat
2600 mg/kg
LC50
Inhalation
Rat
2,700 mg/m3
Remarks: Lungs, Thorax, or Respiration:Other changes.
LD50
Oral
Mouse
3100 mg/kg
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LC50
Inhalation
Mouse
750 ppm
9M
LD50
Oral
Rabbit
4160 mg/kg
LD50
Oral
Guinea pig
5500 mg/kg
LD50
Oral
Mammal
440 mg/kg
IRRITATION DATA
Eyes
Remarks: Severe irritation effect
Skin
Remarks: Severe irritation effect
SIGNS AND SYMPTOMS OF EXPOSURE
Material is extremely destructive to tissue of the mucous
membranes and upper respiratory tract, eyes, and skin.
Inhalation may result in spasm, inflammation and edema of the
larynxand bronchi, chemical pneumonitis, and pulmonary edema.
Symptoms of exposure may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea, and
vomiting. Exposure can cause: Cyanosis. Cardiovascular effects.
Respiratory depression.
ROUTE OF EXPOSURE
Skin Contact: Causes severe burns.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: Causes severe burns.
Inhalation: May be fatal if inhaled. Material is extremely
destructive to the tissue of the mucous membranes and upper
respiratory tract.
Ingestion: May be harmful if swallowed.
TARGET ORGAN INFORMATION
Nerves. Lungs.
12 - Ecological Information
ECOTOXICOLOGICAL EFFECTS
Test Type: EC50 Daphnia
Species: Daphnia magna
Time: 24 h
Value: 1.07 mg/l
Test Type: LC50 Fish
Species: Lepomis macrochirus (Bluegill)
Time: 24 h
Value: 0.52 mg/l
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Test Type: LC50 Fish
Species: Lepomis macrochirus (Bluegill)
Time: 24 h
Value: 0.31 mg/l
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
UN#: 1744
Class: 8
PG: I
Proper Shipping Name: Bromine
IMDG
UN#: 1744
Class: 8
PG: I
Subrisk: 6.1
Proper Shipping Name: Bromine
Marine Pollutant: No
Severe Marine Pollutant: No
IATA
UN#: 1744
Class: 8
PG: I
Subrisk: 6.1
Proper Shipping Name: Bromine
Inhalation Packing Group I: No
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 035-001-00-5
INDICATION OF DANGER: T+ C N
Very toxic. Corrosive. Dangerous for the environment.
R-PHRASES: 26 35 50
Very toxic by inhalation. Causes severe burns. Very toxic to
aquatic organisms.
S-PHRASES: 7/9 26 45 61
Keep container tightly closed and in well-ventilated place. In
case of contact with eyes, rinse immediately with plenty of
water and seek medical advice. In case of accident or if you
feel unwell, seek medical advice immediately (show the label
where possible). Avoid release to the environment. Refer to
special instructions/safety data sheets.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 2
SWITZERLAND
SWISS POISON CLASS: 2
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16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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